View source for Talk:Interneuron

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== Acetylcholine ==

Why has the term neuromodulator been used to describe acetylcholine in the sentence "...releasing neuromodulators like acetylcholine"? In interneurons, it clearly functions as a neurotransmitter.  <span style="font-size: smaller;" class="autosigned">—Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/212.149.175.249|212.149.175.249]] ([[User talk:212.149.175.249|talk]]) 07:56, 3 August 2010 (UTC)</span><!-- Template:UnsignedIP --> <!--Autosigned by SineBot-->

== Illustration ==

I can't read it. Higher res?  <span style="font-size: smaller;" class="autosigned">—Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/131.215.17.231|131.215.17.231]] ([[User talk:131.215.17.231|talk]]) 20:30, 22 September 2008 (UTC)</span><!-- Template:UnsignedIP --> <!--Autosigned by SineBot-->

== Separate brain and spinal cord sections? ==
I wondered if this is a bit confusing.  The text about the various meanings of this term is mixed together while the only diagram is of a reflex arc (i.e. in the spinal cord).  I'd quite like to have two headings, one for spinal cord interneurons and one for cortical inhibitory interneurons.  Anyone have any opinions?  I'll have a think about it and get back to it when I get a chance.  I have a feeling this could get very complicated...  [[User:HilJackson|HilJackson]] 09:51, 4 July 2006 (UTC) <small>[[User talk:HilJackson|Talk to me‼]]</small>

== Example paragraph ==
I'm pretty sure the CNS example ("An example of interneurons is inhibitory interneurons in the neocortex which selectively inhibit sections of the thalamus...") and reference to SICI are inaccurate. The paragraph should probably be scrapped entirely but I thought I'd check first to see if anyone wants to do some research and clean it up.[[User:PhineasG|PhineasG]] ([[User talk:PhineasG|talk]]) 14:16, 12 February 2008 (UTC)

Definitely incorrect.  I'm currently writing a thesis on the topic.  Upon defending in a few weeks, I'll try to expand and clean up this page. [[Special:Contributions/68.46.183.96|68.46.183.96]] ([[User talk:68.46.183.96|talk]]) 21:03, 8 July 2008 (UTC)

== Bipolar neuron ==

"Interneuron" is not synonymous with "bipolar neuron". An interneuron is defined as a neuron that connects afferent and efferent neurons, whereas "bipolar neuron" refers to a specific structural class of neuron (notably found in the [[retina]]). Bipolar neurons are interneurons, but not all interneurons are bipolar neurons. Hence, the terms cannot be used interchangeably. [[User:Fuzzform|Fuzzform]] ([[User talk:Fuzzform|talk]]) 18:46, 9 September 2008 (UTC)

== Definitions ==

I've just rewritten the lede from {{quotation|An '''interneuron''' (also called '''relay neuron''', '''association neuron''', '''connector neuron''' or '''local circuit neuron''') is a multipolar neuron which connects [[afferent neuron]]s and [[efferent neuron]]s in [[neural pathway]]s found within the [[central nervous system]] and the [[enteric nervous system]].}}
to {{quotation|An '''interneuron''' (also called '''relay neuron''', '''association neuron''', '''connector neuron''' or '''local circuit neuron''') is a [[neuron]] that forms a connection between other neurons. Interneurons are neither [[motor neuron|motor]] nor [[sensory neuron|sensory]]. The term is also applied to brain and spinal cord neurons whose [[axon]]s connect only with nearby neurons, to distinguish them from "projection" neurons, whose axons project to more distant regions of the brain or spinal cord.}}
I relied on the following sources:

*{{cite book|last=Purpura|first=DP|editor=MAB Brazier|title=The Interneuron|url=http://books.google.com/books?id=_Dxgrm7dV0kC&pg=PA528|accessdate=16 February 2012|publisher=University of California Press|page=528|chapter=Summation|year=1969}}<br>{{xt|An interneuron is a neuron that connects neurons with neurons.}}
*{{cite book|author1=Rod Plotnik|author2=Haig Kouyoumdjian|title=Introduction to Psychology|url=http://books.google.com/books?id=iSUSoasu8LkC&pg=PA56|accessdate=16 February 2012|date=19 March 2010|publisher=Cengage Learning|isbn=978-0-495-90344-4|pages=56–}}<br>{{xt|An interneuron is a relatively short neuron whose primary task is making connections between other neurons.}}
*{{cite book|author=Max Rechtman|title=CliffsStudySolver Biology|url=http://books.google.com/books?id=fHxcHt5mXm8C&pg=PA137|accessdate=16 February 2012|date=25 June 2004|publisher=John Wiley & Sons|isbn=978-0-7645-5842-9|pages=137–}}<br>{{xt|An interneuron is a neuron located in the spinal cord that receives the nerve impulse from the sensory neuron and relays the impulse to the motor neuron. (In a section addressing the reflex arc.)}}
*{{cite book|author=Michael J. Zigmond|title=Fundamental neuroscience|url=http://books.google.com/books?id=X8NpAAAAMAAJ|accessdate=16 February 2012|year=1999|publisher=Academic Press|isbn=978-0-12-780870-3|page=890}}<br>{{xt|An interneuron is a nerve cell whose cell body and axon reside entirely within the central nervous system.}}
*{{cite book|author=Per Brodal|title=The central nervous system: structure and function|url=http://books.google.com/books?id=iJjI6yDNmr8C&pg=PA9|accessdate=16 February 2012|date=29 March 2010|publisher=Oxford University Press|isbn=978-0-19-538115-3|pages=9–}}<br>{{xt|Its name implies that an interneuron is intercalated between two other neurons ( Fig. 1.12). Even though, strictly speaking, all neurons with axons that do not leave the CNS are thus interneurons, the term is usually restricted to neurons with short axons that do not leave one particular neuronal group. }}
*{{cite book|author=Michael J. Padilla|title=Human biology and health|url=http://books.google.com/books?id=M6LZAAAAMAAJ|accessdate=16 February 2012|year=2002|publisher=Prentice Hall|isbn=978-0-13-054069-0|page=192}}<br>{{xt|An interneuron is a neuron that carries nerve impulses from one neuron to another. Some interneurons pass impulses from sensory neurons to motor neurons.}}
*[http://www.nlm.nih.gov/cgi/mesh/2011/MB_cgi?mode=&term=Interneurons MeSH descriptor data] Retrieved 16 February 2012.<br>{{xt|Most generally any neurons which are not motor or sensory. Interneurons may also refer to neurons whose axons remain within a particular brain region as contrasted with projection neurons which have axons projecting to other brain regions.}}

My main motivation was to remove the implication that interneurons only connect afferent with efferent neurons, and - though I'm not certain on this point - allow for the possibility of PNS interneurons. I have a vague memory that an interneuron stands between the ventral root and its motoneurons. --[[User:Anthonyhcole|Anthonyhcole]] ([[User talk:Anthonyhcole|talk]]) 07:10, 16 February 2012 (UTC)

--[[User:Anthonyhcole|Anthonyhcole]] ([[User talk:Anthonyhcole|talk]]) 06:59, 16 February 2012 (UTC)

:I think that's a good change.  The new definition may not be perfect, but it's surely a big improvement. [[User:Looie496|Looie496]] ([[User talk:Looie496|talk]]) 00:08, 17 February 2012 (UTC)

== Myofibrils ==

In the section "The withdrawal reflex", myofibrils are not the same as muscle fibres. The muscle fibre is the whole muscle cell or myocyte, and the miofibrils are inside the cell. The neuromodulator acetylcholine depolarize the cell, not the miofibrils. It interacts with the plasma membrane (sarcolemma) in the neuromuscular junction.--[[User:Miguelferig|Miguelferig]] ([[User talk:Miguelferig|talk]]) 19:55, 5 August 2015 (UTC)
:As a matter of fact, virtually everything in that section was wrong.  After thinking about it, I decided the best thing to do was to remove the whole section.  It would certainly be good to have a section on the role of spinal interneurons in reflexes, but I think it would be easier to write something from scratch than to fix all the errors there.  (It has the look of a student class assignment, one of the most common sources of junk in Wikipedia.) [[User:Looie496|Looie496]] ([[User talk:Looie496|talk]]) 22:01, 5 August 2015 (UTC)

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