Vesicular transport protein: Difference between revisions

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Crystal structure of the vesicular transport protein

A vesicular transport protein, or vesicular transporter, is a membrane protein that regulates or facilitates the movement of specific molecules across a vesicle's membrane.^[1] As a result, vesicular transporters govern the concentration of molecules within a vesicle.

Types

Examples include:

Archain
ARFs
Clathrin
Caveolin
Dynamin and related proteins, such as the EHD protein family
Rab proteins
SNAREs
Vesicular transport adaptor proteins e.g. Sorting nexins
Synaptotagmin
TRAPP complex
Synaptophysin
Auxilin

Pathways

There are multiple pathways, each using its own coat and GTPase.^[2]

COP 1 (Cytosolic coat protein complex ) : retrograde transport; Golgi ----> Endoplasmic reticulum
COP 2 (Cytosolic coat protein complex ) : anterograde transport; RER -----> cis-Golgi
Clathrin : trans-Golgi ----> Lysosomes, Plasma membrane ----> Endosomes (receptor-mediated endocytosis)

References

^ Vesicular+Transport+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
^ Yasushi Sako (1 October 2010). Cell Signaling Reactions: Single-Molecular Kinetic Analysis. Springer. pp. 168–. ISBN 978-90-481-9863-4. Retrieved 15 December 2010.

This membrane protein–related article is a stub. You can help Wikipedia by expanding it.

[1] Vesicular+Transport+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

[Sako2010-2] Yasushi Sako (1 October 2010). Cell Signaling Reactions: Single-Molecular Kinetic Analysis. Springer. pp. 168–. ISBN 978-90-481-9863-4. Retrieved 15 December 2010.

[1]

[2]

@@ Line 1: / Line 1: @@
+[[File:Crystal Structure of the Vesicular Transport Protein Sec17.jpg|thumb|280px|[[Crystal structure]] of the vesicular [[transport protein]]]]
-A '''vesicular transport protein''' is a [[membrane protein|transmembrane or membrane associated protein]]. It regulates or facilitates the movement by [[vesicle (biology)|vesicles]] of the contents of the cell.<ref>{{MeshName|Vesicular+Transport+Proteins}}</ref>
+A '''vesicular transport protein''', or '''vesicular transporter''', is a [[membrane protein]] that regulates or facilitates the movement of specific molecules across a [[vesicle (biology and chemistry)|vesicle's]] [[biological membrane|membrane]].<ref>{{MeshName|Vesicular+Transport+Proteins}}</ref> As a result, vesicular transporters govern the concentration of molecules within a vesicle.
 ==Types==
@@ Line 10: / Line 11: @@
 * [[Rab (G-protein)|Rab proteins]]
 * [[SNARE (protein)|SNAREs]]
-* [[Sorting nexins]]
+* [[Vesicular transport adaptor proteins]] e.g. [[Sorting nexins]]
 * [[Synaptotagmin]]
+* [[TRAPP complex]]
+* [[Synaptophysin]]
+* [[Auxilin]]
 ==Pathways==
-There are multiple pathways, each using its own coat and [[GTPase]].<ref name="Sako2010">{{cite book|author=Yasushi Sako|title=Cell Signaling Reactions: Single-Molecular Kinetic Analysis|url=http://books.google.com/books?id=eM_fySpFdLkC&pg=PA168|accessdate=15 December 2010|date=1 October 2010|publisher=Springer|isbn=9789048198634|pages=168–}}</ref>
+There are multiple pathways, each using its own coat and [[GTPase]].<ref name="Sako2010">{{cite book|author=Yasushi Sako|title=Cell Signaling Reactions: Single-Molecular Kinetic Analysis|url=https://books.google.com/books?id=eM_fySpFdLkC&pg=PA168|access-date=15 December 2010|date=1 October 2010|publisher=Springer|isbn=978-90-481-9863-4|pages=168–}}</ref>
-* [[COP 1]] (Cytosolic coat protein complex ) : retrograde transport ; [[Golgi apparatus|Golgi]] ----> [[Endoplasmic reticulum]]
+* [[COP 1]] (Cytosolic coat protein complex ) : retrograde transport; [[Golgi apparatus|Golgi]] ----> [[Endoplasmic reticulum]]
-* [[COP 2]] (Cytosolic coat protein complex ) : anterograde transport ; [[RER]] -----> [[cis-Golgi]]
+* [[COP 2]] (Cytosolic coat protein complex ) : anterograde transport; [[Réseau Express Régional|RER]] -----> [[Golgi apparatus#Structure|cis-Golgi]]
-* [[Clathrin]] : trans-Golgi  ----> [[Lysosome]]s , [[Plasma membrane]] ----> [[Endosome]]s ([[receptor-mediated endocytosis]])
+* [[Clathrin]] : trans-Golgi  ----> [[Lysosome]]s, [[Plasma membrane]] ----> [[Endosome]]s ([[receptor-mediated endocytosis]])
 ==See also==
 * [[Membrane transport protein]]
-* [[Wikipedia:MeSH_D12.776#MeSH_D12.776.543.990_---_vesicular_transport_proteins]]
+* [[Wikipedia:MeSH D12.776#MeSH D12.776.543.990 --- vesicular transport proteins]]
 ==References==
 {{reflist}}
-{{membrane-protein-stub}}
 {{Vesicular transport proteins}}
-[[Category:Transport proteins]]
+[[Category:Vesicular transport proteins]]
 [[Category:Peripheral membrane proteins]]
-[[ru:Белки везикулярного транспорта]]
+{{membrane-protein-stub}}