Nuclear atypia: Difference between revisions
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[[File:Glioblastoma with extreme nuclear enlargement - very high mag.jpg|thumb|[[Micrograph]] showing extreme nuclear atypia in [[cancer]] ([[glioblastoma]]). [[Brain biopsy]]. [[HPS stain]].]] |
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[[File:Cytopathology of reactive urothelial changes.png|thumb|Cytopathology of reactive urothelial changes, [[Pap stain]], showing [[urothelial cell]]s with enlarged nuclei but a [[nucleus-cytoplasm ratio]] of less than 0.5. There are bacteria, as well as an inflammatory response of [[neutrophil]]s, providing a cause for the changes.]] |
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'''Nuclear atypia''' refers to abnormal appearance of [[cell nucleus|cell nuclei]]. It is a term used in [[cytopathology]] and [[histopathology]]. Atypical nuclei are often [[pleomorphism (cytology)|pleomorphic]]. |
'''Nuclear atypia''' refers to abnormal appearance of [[cell nucleus|cell nuclei]]. It is a term used in [[cytopathology]] and [[histopathology]]. Atypical nuclei are often [[pleomorphism (cytology)|pleomorphic]]. |
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Nuclear atypia can be seen in reactive changes, [[Precancerous condition|pre-neoplastic changes]] and [[malignancy]]. Severe nuclear atypia is, in most cases, considered an indicator of [[malignancy]]. |
Nuclear atypia can be seen in reactive changes, [[Precancerous condition|pre-neoplastic changes]] and [[malignancy]]. Severe nuclear atypia is, in most cases, considered an indicator of [[malignancy]]. |
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==See also== |
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*[[Arias-Stella reaction]] |
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*[[NC ratio]] |
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*[[Nuclear pleomorphism]] |
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Latest revision as of 18:32, 16 September 2022
Nuclear atypia refers to abnormal appearance of cell nuclei. It is a term used in cytopathology and histopathology. Atypical nuclei are often pleomorphic.
Nuclear atypia can be seen in reactive changes, pre-neoplastic changes and malignancy. Severe nuclear atypia is, in most cases, considered an indicator of malignancy.
See also
[edit]_histopatholgy.jpg){kind=small} | This article related to pathology is a stub. You can help Wikipedia by expanding it. |