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'''Bunaftine''' (or '''bunaphtine'''<ref name="pmid7436628">{{cite journal |author=Tamargo J |title=Electrophysiological effects of bunaphtine in guinea-pig ventricular fibers |journal=Arch Int Pharmacodyn Ther |volume=246 |issue=2 |pages=224–36 |date=August 1980 |pmid=7436628 }}</ref>) is an [[antiarrhythmic agent]].<ref name="pmid6876382">{{cite journal |vauthors=Ferro G, Chiariello M, Tari MG, Vigorito C, Ungaro B, Condorelli M |title=Intropic effects of several antiarrhythmic drugs |journal=Jpn Heart J |volume=24 |issue=3 |pages=377–90 |date=May 1983 |pmid=6876382 |doi= 10.1536/ihj.24.377}}</ref> It is classified in [[class III antiarrhythmic|class III]].<ref name="pmid328029">{{cite journal |vauthors=Fenici R, Marchei M, Bellocci F, Zecchi P |title=Effect of bunaphtine on right atrial repolarisation in man |journal=Br Heart J |volume=39 |issue=7 |pages=787–94 |date=July 1977 |pmid=328029 |pmc=483317 |doi= 10.1136/hrt.39.7.787|url=}}</ref>
'''Bunaftine''' (or '''bunaphtine'''<ref name="pmid7436628">{{cite journal |author=Tamargo J |title=Electrophysiological effects of bunaphtine in guinea-pig ventricular fibers |journal=Arch Int Pharmacodyn Ther |volume=246 |issue=2 |pages=224–36 |date=August 1980 |pmid=7436628 }}</ref>) is an [[antiarrhythmic agent]].<ref name="pmid6876382">{{cite journal |vauthors=Ferro G, Chiariello M, Tari MG, Vigorito C, Ungaro B, Condorelli M |title=Intropic effects of several antiarrhythmic drugs |journal=Jpn Heart J |volume=24 |issue=3 |pages=377–90 |date=May 1983 |pmid=6876382 |doi= 10.1536/ihj.24.377|doi-access=free }}</ref> It is classified in [[class III antiarrhythmic|class III]].<ref name="pmid328029">{{cite journal |vauthors=Fenici R, Marchei M, Bellocci F, Zecchi P |title=Effect of bunaphtine on right atrial repolarisation in man |journal=Br Heart J |volume=39 |issue=7 |pages=787–94 |date=July 1977 |pmid=328029 |pmc=483317 |doi= 10.1136/hrt.39.7.787|url=}}</ref>


==References==
==References==

Latest revision as of 01:56, 29 January 2023

Bunaftine
Clinical data
ATC code
Identifiers
  • N-[2-(Diethylamino)ethyl]-N-propylnaphthalene-1-carboxamide
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.046.373 Edit this at Wikidata
Chemical and physical data
FormulaC21H30N2O
Molar mass326.484 g·mol−1
3D model (JSmol)
  • O=C(N(CCCC)CCN(CC)CC)c2cccc1ccccc12
  • InChI=1S/C21H30N2O/c1-4-7-15-23(17-16-22(5-2)6-3)21(24)20-14-10-12-18-11-8-9-13-19(18)20/h8-14H,4-7,15-17H2,1-3H3 checkY
  • Key:WWGZXRYELYWJBD-UHFFFAOYSA-N checkY
  (verify)

Bunaftine (or bunaphtine[1]) is an antiarrhythmic agent.[2] It is classified in class III.[3]

References

[edit]
  1. ^ Tamargo J (August 1980). "Electrophysiological effects of bunaphtine in guinea-pig ventricular fibers". Arch Int Pharmacodyn Ther. 246 (2): 224–36. PMID 7436628.
  2. ^ Ferro G, Chiariello M, Tari MG, Vigorito C, Ungaro B, Condorelli M (May 1983). "Intropic effects of several antiarrhythmic drugs". Jpn Heart J. 24 (3): 377–90. doi:10.1536/ihj.24.377. PMID 6876382.
  3. ^ Fenici R, Marchei M, Bellocci F, Zecchi P (July 1977). "Effect of bunaphtine on right atrial repolarisation in man". Br Heart J. 39 (7): 787–94. doi:10.1136/hrt.39.7.787. PMC 483317. PMID 328029.