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{{Short description|RNA Family}}
{{Rfam_box|acc=RF00077| description=SraB RNA |abbreviation=SraB |avg_length=160.00 |avg_identity=87.00 |type=Gene; sRNA; |se=Bateman A |ss=Predicted; PFOLD |release=10.0}}
{{Infobox rfam
| Name = SraB RNA
| image = RF00077.jpg
| width =
| caption = Predicted [[secondary structure]] and [[sequence conservation]] of SraB
| Symbol = SraB
| AltSymbols = sraB
| Rfam = RF00077
| miRBase =
| miRBase_family =
| RNA_type = [[Gene]]; [[Bacterial small RNA|sRNA]]
| Tax_domain = [[Bacteria]]
| GO =
| SO = {{SO|0000655}}
| CAS_number =
| EntrezGene =
| HGNCid =
| OMIM =
| PDB =
| RefSeq =
| Chromosome =
| Arm =
| Band =
| LocusSupplementaryData =
}}


The '''SraB RNA''' is a small [[non-coding RNA]] discovered in ''[[E. coli]]'' during a large scale experimental screen<ref name=ref1>{{cite journal | last = Argaman | first = L | coauthors = Hershberg R, Vogel J, Bejerano G, Wagner EG, Margalit H, Altuvia S | year = 2001 | title = Novel small RNA-encoding genes in the intergenic regions of Escherichia coli | journal = Curr Biol | volume = 11 | pages = 941&ndash;950 | pmid = 11448770 | doi = 10.1016/S0960-9822(01)00270-6 | issue = 12}}</ref>. The 14 novel RNAs discovered were named sra (A, B, etc) for '''s'''mall '''R'''N'''A'''. This ncRNA was found to be expressed only in [[stationary phase]]<ref name=ref1 />. The exact function of this RNA is unknown but it has been shown to affect survival of ''[[Salmonella enterica]]'' to antibiotic administration in [[egg albumin]].<ref name="pmid21268901">{{cite journal |author=Jiang H, Cao M, Cao X, Gu H, Zeng K |title=[sRNA (sraB) regulate the resistant ability of Salmonella enterica serovar enteritidis to egg albumen] |language=Chinese |journal=Wei Sheng Wu Xue Bao |volume=50 |issue=11 |pages=1537–44 |year=2010 |month=November |pmid=21268901 |doi= |url=}}</ref> The authors suggest this may be due to SraB regulating a response to components in albumin.
The '''SraB RNA''' is a small [[non-coding RNA]] discovered in ''[[E. coli]]'' during a large scale experimental screen.<ref name="ref1">{{cite journal | last = Argaman | first = L |author2=Hershberg R |author3=Vogel J |author4=Bejerano G |author5=Wagner EG |author6=Margalit H |author7=Altuvia S | year = 2001 | title = Novel small RNA-encoding genes in the intergenic regions of Escherichia coli | journal = Curr Biol | volume = 11 | pages = 941–950 | pmid = 11448770 | doi = 10.1016/S0960-9822(01)00270-6 | issue = 12| s2cid = 18532334 | doi-access = free }}</ref> The 14 novel RNAs discovered were named 'sra' for '''s'''mall '''R'''N'''A''', examples include [[SraC/RyeA RNA|SraC]], [[SraD RNA|SraD]] and [[SraG RNA|SraG]].<ref name="ref1" /> This ncRNA was found to be expressed only in [[stationary phase (biology)|stationary phase]].<ref name="ref1" /> The exact function of this RNA is unknown but it has been shown to affect survival of ''[[Salmonella enterica]]'' to antibiotic administration in [[egg albumin]].<ref name="pmid21268901">{{cite journal |vauthors=Jiang H, Cao M, Cao X, Gu H, Zeng K |title=[sRNA (sraB) regulate the resistant ability of Salmonella enterica serovar enteritidis to egg albumen] |language=zh |journal=Wei Sheng Wu Xue Bao |volume=50 |issue=11 |pages=1537–1544 |date=November 2010 |pmid=21268901 }}</ref> The authors suggest this may be due to SraB regulating a response to components in albumin.


==See Also==
==See also==
* [[Escherichia coli sRNA]]
* [[Escherichia coli sRNA]]


==References==
==References==
⚫
{{reflist}}

⚫
{{reflist|1}}


==External links==
==External links==

* {{Rfam|id=RF00077|name=SraB RNA}}
* {{Rfam|id=RF00077|name=SraB RNA}}


Latest revision as of 17:33, 9 February 2023

SraB RNA
Predicted secondary structure and sequence conservation of SraB
Identifiers
SymbolSraB
Alt. SymbolssraB
RfamRF00077
Other data
RNA typeGene; sRNA
Domain(s)Bacteria
SOSO:0000655
PDB structuresPDBe

The SraB RNA is a small non-coding RNA discovered in E. coli during a large scale experimental screen.[1] The 14 novel RNAs discovered were named 'sra' for small RNA, examples include SraC, SraD and SraG.[1] This ncRNA was found to be expressed only in stationary phase.[1] The exact function of this RNA is unknown but it has been shown to affect survival of Salmonella enterica to antibiotic administration in egg albumin.[2] The authors suggest this may be due to SraB regulating a response to components in albumin.

See also

[edit]

References

[edit]
  1. ^ a b c Argaman, L; Hershberg R; Vogel J; Bejerano G; Wagner EG; Margalit H; Altuvia S (2001). "Novel small RNA-encoding genes in the intergenic regions of Escherichia coli". Curr Biol. 11 (12): 941–950. doi:10.1016/S0960-9822(01)00270-6. PMID 11448770. S2CID 18532334.
  2. ^ Jiang H, Cao M, Cao X, Gu H, Zeng K (November 2010). "[sRNA (sraB) regulate the resistant ability of Salmonella enterica serovar enteritidis to egg albumen]". Wei Sheng Wu Xue Bao (in Chinese). 50 (11): 1537–1544. PMID 21268901.
[edit]
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