OR52R1: Difference between revisions

OR52R1
Identifiers
Aliases	OR52R1, OR11-22, olfactory receptor family 52 subfamily R member 1 (gene/pseudogene), olfactory receptor family 52 subfamily R member 1
External IDs	MGI: 3030403; HomoloGene: 17500; GeneCards: OR52R1; OMA:OR52R1 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	4,804,380 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	102,540,089 bp
RNA expression pattern
	Top expressed in
	prostate;
	Top expressed in
	respiratory epithelium; ; nasal epithelium; ; olfactory epithelium;
	More reference expression data
	n/a
Gene ontology
Molecular function	G protein-coupled receptor activity; olfactory receptor activity; signal transducer activity;
Cellular component	integral component of membrane; plasma membrane; membrane;
Biological process	sensory perception of smell; signal transduction; response to stimulus; detection of chemical stimulus involved in sensory perception of smell; G protein-coupled receptor signaling pathway;
	Sources:Amigo / QuickGO
Orthologs
	119695
	259092
	ENSG00000279270
	ENSMUSG00000062142
	Q8NGF1
	Q8VGZ2
	NM_001005177
	NM_147088
	NP_001005177
	NP_667299
	Wikidata
View/Edit Human	View/Edit Mouse

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Latest revision as of 00:43, 4 March 2023

Olfactory receptor 52R1 is a protein that in humans is encoded by the OR52R1 gene.^[5]

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000279270 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000062142 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b "Entrez Gene: OR52R1 olfactory receptor, family 52, subfamily R, member 1".

External links

OR52R1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This transmembrane receptor-related article is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000279270 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000062142 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: OR52R1 olfactory receptor, family 52, subfamily R, member 1".

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@@ Line 1: / Line 1: @@
+{{Short description|Protein-coding gene in the species Homo sapiens}}
 {{Infobox_gene}}
-'''Olfactory receptor 52R1''' is a [[protein]] that in humans is encoded by the ''OR52R1'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR52R1 olfactory receptor, family 52, subfamily R, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=119695| accessdate = }}</ref>
+'''Olfactory receptor 52R1''' is a [[protein]] that in humans is encoded by the ''OR52R1'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR52R1 olfactory receptor, family 52, subfamily R, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=119695}}</ref>
-Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR52R1 olfactory receptor, family 52, subfamily R, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=119695| accessdate = }}</ref>
+Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR52R1 olfactory receptor, family 52, subfamily R, member 1| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=119695}}</ref>
 ==See also==
@@ Line 12: / Line 13: @@
 ==Further reading==
 {{refbegin | 2}}
-*{{cite journal  | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100  | pmc=356993  }}
+*{{cite journal  | vauthors=Malnic B, Godfrey PA, Buck LB |title=The human olfactory receptor gene family. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 8 |pages= 2584–9 |year= 2004 |pmid= 14983052 |doi=10.1073/pnas.0307882100  | pmc=356993  |bibcode=2004PNAS..101.2584M |doi-access=free }}
 {{refend}}