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{{Infobox rfam
{{Rfam_box|acc=RF00451|description=mir-395 microRNA precursor family|abbreviation=mir-395|type=Gene; miRNA;|avg_length=99.7|avg_identity=64|ss=Predicted; PFOLD|se=Moxon SJ|type=Gene; miRNA;}}
| Name = mir-395 microRNA precursor family
| image = RF00451.jpg
| width =
| caption = Predicted [[secondary structure]] and [[sequence conservation]] of mir-395
| Symbol = mir-395
| AltSymbols =
| Rfam = RF00451
| miRBase = MI0001007
| miRBase_family = MIPF0000016
| RNA_type = [[Gene]]; [[MicroRNA|miRNA]]
| Tax_domain = [[Eukaryota]]
| GO = {{GO|0035195}} {{GO|0035068}}
| SO = {{SO|0001244}}
| CAS_number =
| EntrezGene =
| HGNCid =
| OMIM =
| PDB =
| RefSeq =
| Chromosome =
| Arm =
| Band =
| LocusSupplementaryData =
}}


'''mir-395''' is a [[non-coding RNA]] called a [[microRNA]] that was identified in both ''[[Arabidopsis thaliana]]'' and ''[[Oryza sativa]]'' computationally and was later experimentally verified. mir-395 is thought to target [[mRNA]]s coding for [[ATP sulphurylase]]s.<ref>{{cite journal | last = Jones-Rhoades | first = MW | coauthors = Bartel DP | year = 2004 | title = Computational Identification of Plant MicroRNAs and Their Targets, Including a Stress-Induced miRNA | journal = Mol Cell | volume = 14 | pages = 787&ndash;799 | id = PMID 15200956}}</ref> The mature sequence is excised from the 3' arm of the [[Stem-loop|hairpin]].
'''mir-395''' is a [[non-coding RNA]] called a [[microRNA]] that was identified in both ''[[Arabidopsis thaliana]]'' and ''[[Oryza sativa]]'' computationally and was later experimentally verified. mir-395 is thought to target [[mRNA]]s coding for [[ATP sulphurylase]]s.<ref>{{cite journal | vauthors = Jones-Rhoades MW, Bartel DP | title = Computational identification of plant microRNAs and their targets, including a stress-induced miRNA | journal = Molecular Cell | volume = 14 | issue = 6 | pages = 787–99 | date = June 2004 | pmid = 15200956 | doi = 10.1016/j.molcel.2004.05.027 | doi-access = free }}</ref> The mature sequence is excised from the 3' arm of the [[Stem-loop|hairpin]].


miR-395 is upregulated in ''Arabidopsis'' during [[sulphate]]-limited conditions, when the mature miRNA then regulates sulphur transporters and ATP sulphurylases.<ref>{{cite journal | vauthors = Liang G, Yang F, Yu D | title = MicroRNA395 mediates regulation of sulfate accumulation and allocation in Arabidopsis thaliana | journal = The Plant Journal | volume = 62 | issue = 6 | pages = 1046–57 | date = June 2010 | pmid = 20374528 | doi = 10.1111/j.1365-313X.2010.04216.x | doi-access = free }}</ref><ref>{{cite journal | vauthors = Liang G, Yu D | title = Reciprocal regulation among miR395, APS and SULTR2;1 in Arabidopsis thaliana | journal = Plant Signaling & Behavior | volume = 5 | issue = 10 | pages = 1257–9 | date = October 2010 | pmid = 20935495 | pmc = 3115361 | doi = 10.4161/psb.5.10.12608 }}</ref>
==Reference==


== References ==
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{{reflist|1}}


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{{reflist}}
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==External links==


⚫
== External links ==
* {{Rfam|id=RF00451|name=mir-395 microRNA precursor family}}
* {{Rfam|id=RF00451|name=mir-395 microRNA precursor family}}
* http://microrna.sanger.ac.uk/cgi-bin/sequences/mirna_summary.pl?fam=MIPF0000016 miRBase family entry for mir-395]
* [https://archive.today/20121223110717/http://microrna.sanger.ac.uk/cgi-bin/sequences/mirna_summary.pl?fam=MIPF0000016 miRBase family entry for mir-395]


{{miRNA precursor families}}
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{{molecular-cell-biology-stub}}


[[Category:microRNA]]
[[Category:MicroRNA]]
[[Category:MicroRNA precursor families]]

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{{molecular-cell-biology-stub}}

Latest revision as of 17:52, 12 August 2023

mir-395 microRNA precursor family
Predicted secondary structure and sequence conservation of mir-395
Identifiers
Symbolmir-395
RfamRF00451
miRBaseMI0001007
miRBase familyMIPF0000016
Other data
RNA typeGene; miRNA
Domain(s)Eukaryota
GOGO:0035195 GO:0035068
SOSO:0001244
PDB structuresPDBe

mir-395 is a non-coding RNA called a microRNA that was identified in both Arabidopsis thaliana and Oryza sativa computationally and was later experimentally verified. mir-395 is thought to target mRNAs coding for ATP sulphurylases.[1] The mature sequence is excised from the 3' arm of the hairpin.

miR-395 is upregulated in Arabidopsis during sulphate-limited conditions, when the mature miRNA then regulates sulphur transporters and ATP sulphurylases.[2][3]

References

[edit]
  1. ^ Jones-Rhoades MW, Bartel DP (June 2004). "Computational identification of plant microRNAs and their targets, including a stress-induced miRNA". Molecular Cell. 14 (6): 787–99. doi:10.1016/j.molcel.2004.05.027. PMID 15200956.
  2. ^ Liang G, Yang F, Yu D (June 2010). "MicroRNA395 mediates regulation of sulfate accumulation and allocation in Arabidopsis thaliana". The Plant Journal. 62 (6): 1046–57. doi:10.1111/j.1365-313X.2010.04216.x. PMID 20374528.
  3. ^ Liang G, Yu D (October 2010). "Reciprocal regulation among miR395, APS and SULTR2;1 in Arabidopsis thaliana". Plant Signaling & Behavior. 5 (10): 1257–9. doi:10.4161/psb.5.10.12608. PMC 3115361. PMID 20935495.
[edit]


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