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{{Short description|Class of enzymes}}
{{Infobox enzyme
{{Infobox enzyme
| Name = (+)-Larreatricin hydroxylase
| Name = (+)-Larreatricin hydroxylase
| EC_number = 1.14.99.47
| EC_number = 1.14.99.47
| CAS_number =
| CAS_number =
| GO_code =
| IUBMB_EC_number = 1/14/99/47
| GO_code =
| image =
| image =
| width =
| width =
| caption =
| caption =
}}
}}
'''(+)-Larreatricin hydroxylase''' ({{EC number|1.14.99.47}}) is an [[enzyme]] with system name ''(+)-larreatricin:oxygen 3'-hydroxylase''.<ref>{{cite journal | title = (+)-Larreatricin hydroxylase, an enantio-specific polyphenol oxidase from the creosote bush (<em>Larrea tridentata</em>) |author = Cho, M.H., Moinuddin, S.G., Helms, G.L., Hishiyama, S., Eichinger, D., Davin, L.B. and Lewis, N.G. |journal = Proc. Natl. Acad. Sci. USA |year = 2003 |volume = 100 |pages = 10641–10646 |pmid = 12960376}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]
'''(+)-Larreatricin hydroxylase''' ({{EC number|1.14.99.47}}) is an [[enzyme]] with [[List of enzymes|systematic name]] ''(+)-larreatricin:oxygen 3'-hydroxylase''.<ref>{{cite journal | vauthors = Cho MH, Moinuddin SG, Helms GL, Hishiyama S, Eichinger D, Davin LB, Lewis NG | title = (+)-Larreatricin hydroxylase, an enantio-specific polyphenol oxidase from the creosote bush (Larrea tridentata) | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 19 | pages = 10641–6 | date = September 2003 | pmid = 12960376 | pmc = 196857 | doi = 10.1073/pnas.1934562100 | bibcode = 2003PNAS..10010641C | doi-access = free }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]


: (+)-larreatricin + O<sub>2</sub> + AH<sub>2</sub> <math>\rightleftharpoons</math> (+)-3'-hydroxylarreatricin + A + H<sub>2</sub>O
: (+)-larreatricin + O<sub>2</sub> + AH<sub>2</sub> <math>\rightleftharpoons</math> (+)-3'-hydroxylarreatricin + A + H<sub>2</sub>O


This enzyme is isolated from the plant ''[[Larrea tridentata]]'' (creosote bush) and can be produced recombinantly.<ref>{{cite journal | vauthors = Martin HJ, Kampatsikas I, Oost R, Pretzler M, Al-Sayed E, Roller A, Giester G, Rompel A, Maulide N | display-authors = 6 | title = Total Synthesis, Stereochemical Assignment, and Divergent Enantioselective Enzymatic Recognition of Larreatricin | journal = Chemistry: A European Journal | volume = 24 | issue = 59 | pages = 15756–15760 | date = October 2018 | pmid = 30113748 | pmc = 6220842 | doi = 10.1002/chem.201803785 }}</ref>
This enzyme is isolated from the plant ''[[Larrea tridentata]]'' (creosote bush).


== References ==
== References ==
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== External links ==
== External links ==
* {{MeshName|(+)-larreatricin+hydroxylase}}
* {{MeshName|(+)-larreatricin+hydroxylase}}

{{Dioxygenases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}


[[Category:EC 1.14.99]]
[[Category:EC 1.14.99]]

Latest revision as of 12:15, 26 August 2023

(+)-Larreatricin hydroxylase
Identifiers
EC no.1.14.99.47
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
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NCBIproteins

(+)-Larreatricin hydroxylase (EC 1.14.99.47) is an enzyme with systematic name (+)-larreatricin:oxygen 3'-hydroxylase.[1] This enzyme catalyses the following chemical reaction

(+)-larreatricin + O2 + AH2 (+)-3'-hydroxylarreatricin + A + H2O

This enzyme is isolated from the plant Larrea tridentata (creosote bush) and can be produced recombinantly.[2]

References

[edit]
  1. ^ Cho MH, Moinuddin SG, Helms GL, Hishiyama S, Eichinger D, Davin LB, Lewis NG (September 2003). "(+)-Larreatricin hydroxylase, an enantio-specific polyphenol oxidase from the creosote bush (Larrea tridentata)". Proceedings of the National Academy of Sciences of the United States of America. 100 (19): 10641–6. Bibcode:2003PNAS..10010641C. doi:10.1073/pnas.1934562100. PMC 196857. PMID 12960376.
  2. ^ Martin HJ, Kampatsikas I, Oost R, Pretzler M, Al-Sayed E, Roller A, et al. (October 2018). "Total Synthesis, Stereochemical Assignment, and Divergent Enantioselective Enzymatic Recognition of Larreatricin". Chemistry: A European Journal. 24 (59): 15756–15760. doi:10.1002/chem.201803785. PMC 6220842. PMID 30113748.
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