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{{Short description|American geneticist}}
Shirleen Roeder is a Geneticist and was Eugene Higgins Professor of Genetics and HHMI investigator<ref>{{Cite web|url=https://www.hhmi.org/scientists/g-shirleen-roeder|title="G. Shirleen Roeder, PhD"|last=|first=|date=|website=Howard Hughes Medical Institute|archive-url=|archive-date=|dead-url=|access-date=November 14, 2018}}</ref> in the Molecular, Cellular, and Developmental Biology Department at Yale University before her retirement in 2012; in 2018 she is Professor Emeritus there.<ref>{{Cite web|url=https://mcdb.yale.edu/people/g-shirleen-roeder|title="G. Shirleen Roeder, PhD"|last=|first=|date=|website=Yale University|archive-url=|archive-date=|dead-url=|access-date=November 14, 2018}}</ref> She is noted for identifying and characterizing the yeast genes that regulate the process of meiosis with particular emphasis on synpapsis.<ref name=":0">{{Cite web|url=https://www.asm.org/index.php/aam-fellows/aam-fellows/fellows-elected-in-2010/item/5046-g-shirleen-roeder|title="AAM Fellows G. Shirleen Roeder"|last=|first=|date=|website=American Academy of Microbiology|archive-url=|archive-date=|dead-url=|access-date=November 14, 2018}}</ref> She discovered two distinct processes that regulate the recombination between chromosomes in meiosis and also a process inhibiting recombination.<ref name=":1">{{Cite web|url=http://www.nasonline.org/member-directory/members/20020185.html|title="G Shirleen Roeder, Yale University"|last=|first=|date=|website=National Academy of Sciences|archive-url=|archive-date=|dead-url=|access-date=November 14, 2018}}</ref> Shirleen Roeder was elected to the National Academy of Sciences in 2009.<ref name=":1" />  She was chosen as a Fellow of the American Association for the Advancement of Science<ref>{{Cite web|url=http://www.yalescientific.org/2010/09/yale-scientists-awarded-aaas-fellowship/|title="Yale Scientists Awarded AAAS Fellowship"|last=Luna|first=Regina|date=September 1, 2010|website=Yale Scientific|archive-url=|archive-date=|dead-url=|access-date=November 14, 2018}}</ref> and elected to the American Academy of Microbiology in 2010.<ref name=":0" />
{{Infobox scientist
| name = G. Shirleen Roeder
| image = <!--(filename only, i.e. without "File:" prefix)-->
| caption =
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| death_date = <!--{{death date and age |YYYY|MM|DD |YYYY|MM|DD}} (death date then birth date)-->
| workplaces =
| education =
| alma_mater = University of Toronto
| thesis_title = Recombination, maturation and packaging of the bacteriophage T7 chromosome
| thesis_url = https://www.worldcat.org/oclc/{{{224693462}}}
| thesis_year = 1978
| doctoral_advisor =
| academic_advisors =
| doctoral_students =
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}}

'''Glenna Shirleen Roeder''' is a [[geneticist]] known for identifying and characterizing the [[yeast]] genes that regulate the process of [[meiosis]] with particular emphasis on [[synapsis]].

== Education and career ==
Roeder has a B.Sc. from [[Dalhousie University]] (1973)<ref name=":2">{{Cite web|date=2012|title=Faculty retirement tribute to G. Shirleen Roeder|url=https://fas.yale.edu/book/faculty-retirement-tributes-2012/g-shirleen-roeder|url-status=live|archive-url=https://web.archive.org/web/20211230145442/https://fas.yale.edu/book/faculty-retirement-tributes-2012/g-shirleen-roeder|archive-date=December 30, 2021|access-date=December 30, 2021|website=Yale University}}</ref><ref>{{Cite web|title=science.ca : Shirleen Roeder|url=https://www.science.ca/scientists/scientistprofile.php?pID=437|access-date=2021-12-30|website=www.science.ca}}</ref> and earned her Ph.D. in 1978 from the [[University of Toronto]].<ref>{{Cite thesis|title=Recombination, maturation and packaging of the bacteriophage T7 chromosome|url=https://www.worldcat.org/title/recombination-maturation-and-packaging-of-the-bacteriophage-t7-chromosome/oclc/%7B%7B%7B224693462%7D%7D%7D|publisher=[publisher not identified]|date=1978|place=Toronto|language=English|first=Glenna Shirleen|last=Roeder}}</ref> Following her Ph.D. she was a postdoctoral fellow at [[Cornell University]] before moving to the faculty at [[Yale University]] in 1981.<ref name=":3">{{Cite web|date=June 15, 2001|title=Geneticist Shirleen Roeder named Eugene Higgins Professor|url=http://archives.news.yale.edu/v29.n32/story6.html|access-date=2021-12-30|website=Yale Bulletin and Calendar}}</ref> In 2001 she was named the Eugene Higgins Professor of Genetics in the Molecular, Cellular, and Developmental Biology Department at Yale University.<ref name=":3" /> Roeder retired in 2012<ref name=":2"/> and, as of 2021, she is Professor Emeritus at Yale University.<ref>{{Cite web|title=G Shirleen Roeder, Ph.D. {{!}} Molecular, Cellular and Developmental Biology|url=https://mcdb.yale.edu/people/g-shirleen-roeder|access-date=2021-12-30|website=mcdb.yale.edu|language=en}}</ref>

== Research ==
Roeder used budding yeast as a model system to examine meiosis. She discovered the Zip1 protein,<ref>{{cite journal |last1=Sym |first1=Mary |last2=Engebrecht |first2=JoAnne |last3=Roeder |first3=G. Shirleen |title=ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis |journal=Cell |date=12 February 1993 |volume=72 |issue=3 |pages=365–378 |doi=10.1016/0092-8674(93)90114-6 |pmid=7916652 |s2cid=6174855 |language=English |issn=0092-8674|doi-access=free }}</ref> and discovered two distinct processes that regulate the [[Homologous recombination|recombination]] between [[chromosome]]s in meiosis and also a process inhibiting recombination.<ref name=":1">{{Cite web|title="G Shirleen Roeder, Yale University"|url=http://www.nasonline.org/member-directory/members/20020185.html|access-date=November 14, 2018|website=National Academy of Sciences}}</ref>

==Selected publications==
*{{cite journal |last1=Roeder |first1=G. Shirleen |title=Meiotic chromosomes: it takes two to tango |journal=Genes & Development |date=15 October 1997 |volume=11 |issue=20 |pages=2600–2621 |doi=10.1101/gad.11.20.2600 |pmid=9334324 |url=http://genesdev.cshlp.org/content/11/20/2600.short |language=en |issn=0890-9369|doi-access=free }}
*{{cite journal |last1=Sym |first1=Mary |last2=Engebrecht |first2=JoAnne |last3=Roeder |first3=G. Shirleen |title=ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis |journal=Cell |date=12 February 1993 |volume=72 |issue=3 |pages=365–378 |doi=10.1016/0092-8674(93)90114-6 |pmid=7916652 |s2cid=6174855 |language=English |issn=0092-8674|doi-access=free }}
*{{cite journal |last1=Roeder |first1=G. Shirleen |last2=Bailis |first2=Julie M. |title=The pachytene checkpoint |journal=Trends in Genetics |date=1 September 2000 |volume=16 |issue=9 |pages=395–403 |doi=10.1016/S0168-9525(00)02080-1 |pmid=10973068 |url=https://doi.org/10.1016/S0168-9525(00)02080-1 |language=English |issn=0168-9525}}
*{{cite journal |last1=Ross-Macdonald |first1=Petra |last2=Roeder |first2=G. Shirleen |title=Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction |journal=Cell |date=16 December 1994 |volume=79 |issue=6 |pages=1069–1080 |doi=10.1016/0092-8674(94)90037-X |pmid=8001134 |s2cid=28539509 |url=https://doi.org/10.1016/0092-8674(94)90037-X |language=English |issn=0092-8674}}

==Awards and honors==
In 1984, Roeder received a Young Investigator award from the [[National Science Foundation]].<ref>{{Cite web|title=NSF Award Search: Award # 8351607 - Presidential Young Investigator Award|url=https://www.nsf.gov/awardsearch/showAward?AWD_ID=8351607|access-date=2021-12-30|website=www.nsf.gov}}</ref> She was named an [[Howard Hughes Medical Institute|HHMI]] investigator in 1997,<ref>{{Cite web|title="G. Shirleen Roeder, PhD"|url=https://www.hhmi.org/scientists/g-shirleen-roeder|access-date=November 14, 2018|website=Howard Hughes Medical Institute}}</ref> and was elected to the [[National Academy of Sciences]] in 2009.<ref name=":1" /> In 2010, she was chosen as a Fellow of the [[American Association for the Advancement of Science]]<ref>{{Cite web|last=Luna|first=Regina|date=September 1, 2010|title="Yale Scientists Awarded AAAS Fellowship"|url=http://www.yalescientific.org/2010/09/yale-scientists-awarded-aaas-fellowship/|access-date=November 14, 2018|website=Yale Scientific}}</ref> and elected to the [[American Academy of Microbiology]].<ref name=":0">{{Cite web|title="AAM Fellows G. Shirleen Roeder"|url=https://myasm.asm.org/eweb/DynamicPage.aspx?Site=ASM&WebKey=abbcf18d-3f11-46a6-95d7-956eed2a9cf3&type=acfellows&FromSearchControl=Yes|access-date=November 14, 2018|website=American Academy of Microbiology}}</ref><ref>{{Cite web|title=78 scientists elected to the American Academy of Microbiology|url=https://www.eurekalert.org/news-releases/794013|access-date=2021-12-30|website=EurekAlert!|language=en}}</ref>


==References==
==References==
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{{reflist}}


{{Authority control}}

{{DEFAULTSORT:Roeder, Shirleen}}
[[Category:Meiosis]]
[[Category:American women geneticists]]
[[Category:Yale University faculty]]
[[Category:Living people]]
[[Category:Year of birth missing (living people)]]
[[Category:American geneticists]]
[[Category:American geneticists]]
[[Category:Fellows of the American Association for the Advancement of Science]]


{{geneticist-stub}}

Latest revision as of 16:50, 27 September 2023

G. Shirleen Roeder
Alma materUniversity of Toronto
Scientific career
ThesisRecombination, maturation and packaging of the bacteriophage T7 chromosome (1978)

Glenna Shirleen Roeder is a geneticist known for identifying and characterizing the yeast genes that regulate the process of meiosis with particular emphasis on synapsis.

Education and career

[edit]

Roeder has a B.Sc. from Dalhousie University (1973)[1][2] and earned her Ph.D. in 1978 from the University of Toronto.[3] Following her Ph.D. she was a postdoctoral fellow at Cornell University before moving to the faculty at Yale University in 1981.[4] In 2001 she was named the Eugene Higgins Professor of Genetics in the Molecular, Cellular, and Developmental Biology Department at Yale University.[4] Roeder retired in 2012[1] and, as of 2021, she is Professor Emeritus at Yale University.[5]

Research

[edit]

Roeder used budding yeast as a model system to examine meiosis. She discovered the Zip1 protein,[6] and discovered two distinct processes that regulate the recombination between chromosomes in meiosis and also a process inhibiting recombination.[7]

Selected publications

[edit]
  • Roeder, G. Shirleen (15 October 1997). "Meiotic chromosomes: it takes two to tango". Genes & Development. 11 (20): 2600–2621. doi:10.1101/gad.11.20.2600. ISSN 0890-9369. PMID 9334324.
  • Sym, Mary; Engebrecht, JoAnne; Roeder, G. Shirleen (12 February 1993). "ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis". Cell. 72 (3): 365–378. doi:10.1016/0092-8674(93)90114-6. ISSN 0092-8674. PMID 7916652. S2CID 6174855.
  • Roeder, G. Shirleen; Bailis, Julie M. (1 September 2000). "The pachytene checkpoint". Trends in Genetics. 16 (9): 395–403. doi:10.1016/S0168-9525(00)02080-1. ISSN 0168-9525. PMID 10973068.
  • Ross-Macdonald, Petra; Roeder, G. Shirleen (16 December 1994). "Mutation of a meiosis-specific MutS homolog decreases crossing over but not mismatch correction". Cell. 79 (6): 1069–1080. doi:10.1016/0092-8674(94)90037-X. ISSN 0092-8674. PMID 8001134. S2CID 28539509.

Awards and honors

[edit]

In 1984, Roeder received a Young Investigator award from the National Science Foundation.[8] She was named an HHMI investigator in 1997,[9] and was elected to the National Academy of Sciences in 2009.[7] In 2010, she was chosen as a Fellow of the American Association for the Advancement of Science[10] and elected to the American Academy of Microbiology.[11][12]

References

[edit]
  1. ^ a b "Faculty retirement tribute to G. Shirleen Roeder". Yale University. 2012. Archived from the original on December 30, 2021. Retrieved December 30, 2021.
  2. ^ "science.ca : Shirleen Roeder". www.science.ca. Retrieved 2021-12-30.
  3. ^ Roeder, Glenna Shirleen (1978). Recombination, maturation and packaging of the bacteriophage T7 chromosome (Thesis). Toronto: [publisher not identified].
  4. ^ a b "Geneticist Shirleen Roeder named Eugene Higgins Professor". Yale Bulletin and Calendar. June 15, 2001. Retrieved 2021-12-30.
  5. ^ "G Shirleen Roeder, Ph.D. | Molecular, Cellular and Developmental Biology". mcdb.yale.edu. Retrieved 2021-12-30.
  6. ^ Sym, Mary; Engebrecht, JoAnne; Roeder, G. Shirleen (12 February 1993). "ZIP1 is a synaptonemal complex protein required for meiotic chromosome synapsis". Cell. 72 (3): 365–378. doi:10.1016/0092-8674(93)90114-6. ISSN 0092-8674. PMID 7916652. S2CID 6174855.
  7. ^ a b ""G Shirleen Roeder, Yale University"". National Academy of Sciences. Retrieved November 14, 2018.
  8. ^ "NSF Award Search: Award # 8351607 - Presidential Young Investigator Award". www.nsf.gov. Retrieved 2021-12-30.
  9. ^ ""G. Shirleen Roeder, PhD"". Howard Hughes Medical Institute. Retrieved November 14, 2018.
  10. ^ Luna, Regina (September 1, 2010). ""Yale Scientists Awarded AAAS Fellowship"". Yale Scientific. Retrieved November 14, 2018.
  11. ^ ""AAM Fellows G. Shirleen Roeder"". American Academy of Microbiology. Retrieved November 14, 2018.
  12. ^ "78 scientists elected to the American Academy of Microbiology". EurekAlert!. Retrieved 2021-12-30.


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