Pseudopolyps: Difference between revisions
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{{Infobox medical condition (new) |
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{{infobox disease |
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| name = Pseudopolyps |
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| image = Chronic Ulcerative Colitis 1.jpg |
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| caption = Colonic pseudopolyps of a patient with intractable [[ulcerative colitis]]. Colectomy specimen. |
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| pronounce = |
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| field = [[Gastroenterology]], [[Pathology]] |
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| symptoms = |
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| complications = Bowel obstruction |
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| differential = [[Familial adenomatous polyposis]] |
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'''Pseudopolyps''' are projecting masses of [[scar|scar tissue]] that develop from [[granulation tissue]] during the [[healing]] phase in repeated cycle of [[ulceration]] (especially in [[inflammatory bowel disease]]). [[Inflammation|Inflammatory]] [[Tissue (biology)|tissue]] without [[malignant]] potential,<ref>Ulcerative Colitis: Pseudopolyps; http://www.endoatlas.com/ib_uc_03.html</ref> pseudopolyps may |
'''Pseudopolyps''' are projecting masses of [[scar|scar tissue]] that develop from [[granulation tissue]] during the [[healing]] phase in repeated cycle of [[ulceration]] (especially in [[inflammatory bowel disease]]). [[Inflammation|Inflammatory]] [[Tissue (biology)|tissue]] without [[malignant]] potential,<ref>Ulcerative Colitis: Pseudopolyps; http://www.endoatlas.com/ib_uc_03.html</ref> pseudopolyps may represent either regenerating mucosal islands between areas of ulceration, edematous polypoid tags or granulation tissue covered by epithelium.<ref>{{cite journal |last1=Joffe |first1=N |title=Localised giant pseudopolyposis secondary to ulcerative or granulomatous colitis. |journal=Clinical Radiology |date=November 1977 |volume=28 |issue=6 |pages=609–16 |doi=10.1016/s0009-9260(77)80038-x |pmid=589915}}</ref> There are reported cases when localized giant pseudopolyposis resulted in intestinal obstruction.<ref>{{Cite journal |doi = 10.1259/0007-1285-51-610-782|title = Pseudopolyposis in Crohn's disease|year = 1978|last1 = Freeman|first1 = A. H.|last2 = Berridge|first2 = F. R.|last3 = Dick|first3 = A. P.|last4 = Gleeson|first4 = J. A.|last5 = Zeegen|first5 = R.|journal = The British Journal of Radiology|volume = 51|issue = 610|pages = 782–787|pmid = 709018}}</ref> |
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Residual mucosal islands between ulcerated and denuded areas of mucosa may have a polypoid appearance and are referred to as pseudopolyps.<ref>Utility of High-Resolution MR Imaging in Demonstrating Transmural Pathologic Changes in Crohn Disease |
Residual mucosal islands between ulcerated and denuded areas of mucosa may have a polypoid appearance and are referred to as pseudopolyps.<ref>{{Cite journal |doi = 10.1148/rg.296095503|title = Utility of High-Resolution MR Imaging in Demonstrating Transmural Pathologic Changes in Crohn Disease|year = 2009|last1 = Sinha|first1 = Rakesh|last2 = Rajiah|first2 = Prabhakar|last3 = Murphy|first3 = Paul|last4 = Hawker|first4 = Peter|last5 = Sanders|first5 = Scott|journal = Radiographics|volume = 29|issue = 6|pages = 1847–1867|pmid = 19959525}}</ref> Polyposis syndromes, such as [[familial adenomatous polyposis]], could give rise to a similar appearance on [[Medical imaging|imaging]], although the [[clinical presentation]] would differ from that of inflammatory pseudopolyposis.<ref>{{cite journal |last1=Arluk |first1=GM |last2=Pickhardt |first2=PJ |title=Images in clinical medicine. Inflammatory pseudopolyposis in Crohn's disease. |journal=The New England Journal of Medicine |date=26 February 2004 |volume=350 |issue=9 |pages=923 |doi=10.1056/NEJMicm020629 |pmid=14985490}}</ref> |
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Numerous, confluent ulcerations with bulging of the edematous residual mucosa determine a [[cobblestone]] appearance at endoscopy.<ref>Atlas of Gastroenterological Endoscopy, Crohn´s disease. http://www.endoskopischer-atlas.de/k43e.htm</ref><ref> |
Numerous, confluent ulcerations with bulging of the edematous residual mucosa determine a [[cobblestone]] appearance at endoscopy.<ref>Atlas of Gastroenterological Endoscopy, Crohn´s disease. http://www.endoskopischer-atlas.de/k43e.htm</ref><ref>{{Cite web|url=https://medical-dictionary.thefreedictionary.com/cobblestone+appearance|title=cobblestone appearance|website=TheFreeDictionary.com}}</ref> |
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== References == |
== References == |
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[[Category:Anatomical pathology]] |
[[Category:Anatomical pathology]] |
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[[Category:Gastroenterology]] |
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{{Gastroenterology-stub|}} |
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Latest revision as of 02:49, 5 November 2023
| Pseudopolyps | |
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| Colonic pseudopolyps of a patient with intractable ulcerative colitis. Colectomy specimen. | |
| Specialty | Gastroenterology, Pathology |
| Complications | Bowel obstruction |
| Differential diagnosis | Familial adenomatous polyposis |
Pseudopolyps are projecting masses of scar tissue that develop from granulation tissue during the healing phase in repeated cycle of ulceration (especially in inflammatory bowel disease). Inflammatory tissue without malignant potential,[1] pseudopolyps may represent either regenerating mucosal islands between areas of ulceration, edematous polypoid tags or granulation tissue covered by epithelium.[2] There are reported cases when localized giant pseudopolyposis resulted in intestinal obstruction.[3]
Residual mucosal islands between ulcerated and denuded areas of mucosa may have a polypoid appearance and are referred to as pseudopolyps.[4] Polyposis syndromes, such as familial adenomatous polyposis, could give rise to a similar appearance on imaging, although the clinical presentation would differ from that of inflammatory pseudopolyposis.[5]
Numerous, confluent ulcerations with bulging of the edematous residual mucosa determine a cobblestone appearance at endoscopy.[6][7]
References
[edit]- ^ Ulcerative Colitis: Pseudopolyps; http://www.endoatlas.com/ib_uc_03.html
- ^ Joffe, N (November 1977). "Localised giant pseudopolyposis secondary to ulcerative or granulomatous colitis". Clinical Radiology. 28 (6): 609–16. doi:10.1016/s0009-9260(77)80038-x. PMID 589915.
- ^ Freeman, A. H.; Berridge, F. R.; Dick, A. P.; Gleeson, J. A.; Zeegen, R. (1978). "Pseudopolyposis in Crohn's disease". The British Journal of Radiology. 51 (610): 782–787. doi:10.1259/0007-1285-51-610-782. PMID 709018.
- ^ Sinha, Rakesh; Rajiah, Prabhakar; Murphy, Paul; Hawker, Peter; Sanders, Scott (2009). "Utility of High-Resolution MR Imaging in Demonstrating Transmural Pathologic Changes in Crohn Disease". Radiographics. 29 (6): 1847–1867. doi:10.1148/rg.296095503. PMID 19959525.
- ^ Arluk, GM; Pickhardt, PJ (26 February 2004). "Images in clinical medicine. Inflammatory pseudopolyposis in Crohn's disease". The New England Journal of Medicine. 350 (9): 923. doi:10.1056/NEJMicm020629. PMID 14985490.
- ^ Atlas of Gastroenterological Endoscopy, Crohn´s disease. http://www.endoskopischer-atlas.de/k43e.htm
- ^ "cobblestone appearance". TheFreeDictionary.com.
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