Jump to content

HRX: Difference between revisions

From Wikipedia, the free encyclopedia
Content deleted Content added
SmackBot (talk | contribs)
m Date/fix the maintenance tags or gen fixes using AWB
No edit summary
Tags: Visual edit Mobile edit Mobile web edit Advanced mobile edit
 
(9 intermediate revisions by 8 users not shown)
Line 1: Line 1:
'''HRX''' may refer to:
{{Merge|MLL1|date=November 2007}}


* HRX, a brand by Indian actor [[Hrithik Roshan]], including casual wear and film and television production
<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
* [[Zinc finger protein HRX]], or simply HRX, an enzyme
{{PBB_Controls
* [[Hypo Real Estate]] (stock ticker symbol: HRX), a German company
| update_page = yes
* hrx, the ISO 639 language code of the [[Hunsrik]] language.
| require_manual_inspection = no
| update_protein_box = yes
| update_summary = yes
| update_citations = yes
}}


{{Disambiguation}}
<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{GNF_Protein_box
| image = PBB_Protein_MLL_image.jpg
| image_source = [[Protein_Data_Bank|PDB]] rendering based on 2j2s.
| PDB = {{PDB2|2j2s}}
| Name = Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)
| HGNCid = 7132
| Symbol = MLL
| AltSymbols =; ALL-1; CXXC7; HRX; HTRX1; MLL/GAS7; MLL1A; TRX1
| OMIM = 159555
| ECnumber =
| Homologene = 4338
| MGIid = 96995
| GeneAtlas_image1 = PBB_GE_MLL_212080_at_tn.png
| GeneAtlas_image2 = PBB_GE_MLL_212076_at_tn.png
| GeneAtlas_image3 = PBB_GE_MLL_212078_s_at_tn.png
| Function = {{GNF_GO|id=GO:0003677 |text = DNA binding}} {{GNF_GO|id=GO:0003700 |text = transcription factor activity}} {{GNF_GO|id=GO:0003702 |text = RNA polymerase II transcription factor activity}} {{GNF_GO|id=GO:0004672 |text = protein kinase activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} {{GNF_GO|id=GO:0008270 |text = zinc ion binding}} {{GNF_GO|id=GO:0042803 |text = protein homodimerization activity}} {{GNF_GO|id=GO:0046872 |text = metal ion binding}}
| Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
| Process = {{GNF_GO|id=GO:0006350 |text = transcription}} {{GNF_GO|id=GO:0006355 |text = regulation of transcription, DNA-dependent}} {{GNF_GO|id=GO:0006366 |text = transcription from RNA polymerase II promoter}} {{GNF_GO|id=GO:0006461 |text = protein complex assembly}} {{GNF_GO|id=GO:0006468 |text = protein amino acid phosphorylation}} {{GNF_GO|id=GO:0035162 |text = embryonic hemopoiesis}}
| Orthologs = {{GNF_Ortholog_box
| Hs_EntrezGene = 4297
| Hs_Ensembl = ENSG00000118058
| Hs_RefseqProtein = NP_005924
| Hs_RefseqmRNA = NM_005933
| Hs_GenLoc_db =
| Hs_GenLoc_chr = 11
| Hs_GenLoc_start = 117812415
| Hs_GenLoc_end = 117901146
| Hs_Uniprot = Q03164
| Mm_EntrezGene = 214162
| Mm_Ensembl = ENSMUSG00000002028
| Mm_RefseqmRNA = XM_110671
| Mm_RefseqProtein = XP_110671
| Mm_GenLoc_db =
| Mm_GenLoc_chr = 9
| Mm_GenLoc_start = 44554359
| Mm_GenLoc_end = 44631971
| Mm_Uniprot = Q5DTR3
}}
}}
'''Myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila)''', also known as '''MLL''', is a human [[gene]].

<!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
{{PBB_Summary
| section_title =
| summary_text =
}}

==Further reading==
{{refbegin | 2}}
{{PBB_Further_reading
| citations =
*{{cite journal | author=Marschalek R, Nilson I, Löchner K, ''et al.'' |title=The structure of the human ALL-1/MLL/HRX gene. |journal=Leuk. Lymphoma |volume=27 |issue= 5-6 |pages= 417-28 |year= 1998 |pmid= 9477123 |doi= }}
*{{cite journal | author=Eguchi M, Eguchi-Ishimae M, Greaves M |title=The role of the MLL gene in infant leukemia. |journal=Int. J. Hematol. |volume=78 |issue= 5 |pages= 390-401 |year= 2004 |pmid= 14704031 |doi= }}
*{{cite journal | author=Daser A, Rabbitts TH |title=Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis. |journal=Genes Dev. |volume=18 |issue= 9 |pages= 965-74 |year= 2004 |pmid= 15132992 |doi= 10.1101/gad.1195504 }}
*{{cite journal | author=Li ZY, Liu DP, Liang CC |title=New insight into the molecular mechanisms of MLL-associated leukemia. |journal=Leukemia |volume=19 |issue= 2 |pages= 183-90 |year= 2005 |pmid= 15618964 |doi= 10.1038/sj.leu.2403602 }}
*{{cite journal | author=Douet-Guilbert N, Morel F, Le Bris MJ, ''et al.'' |title=Rearrangement of MLL in a patient with congenital acute monoblastic leukemia and granulocytic sarcoma associated with a t(1;11)(p36;q23) translocation. |journal=Leuk. Lymphoma |volume=46 |issue= 1 |pages= 143-6 |year= 2005 |pmid= 15621793 |doi= 10.1080/104281904000010783 }}
}}
{{refend}}

{{protein-stub}}

Latest revision as of 11:03, 17 November 2023

HRX may refer to: