Odotope theory: Difference between revisions
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{{Short description|Neuropsychological theory}} |
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'''Odotope Theory''', also known as Weak-Shape Theory, is a leading [[neurophysiology|neurophysiological]] theory of how the sense of [[smell]] functions. The model is analogous to a molecular [[Braille]]: it is propsed that any number of the roughly 1000 different [[protein]]-based smell receptors in the nose binds to only certain parts of a smellable [[molecule]], and thus a few hundreds of different receptors can, through [[combinatorial explosion]], theoretically recognize an infinite number of distinct smells. |
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'''Odotope theory''', also known as '''weak shape theory''',<ref>{{cite journal |pmc=1905909 |title=The scent of life. The exquisite complexity of the sense of smell in animals and humans | pmid=17603536 |doi=10.1038/sj.embor.7401029 |volume=8 |issue=7 |date=July 2007 |journal=EMBO Rep. |pages=629–33}}</ref> is a theory of how [[olfactory receptor]]s bind to [[odor]] molecules. The theory proposes that a combination of shape factors determine the coupling. The word itself is an analogy to [[epitope]]s. |
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== See also == |
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Odotope theory sidesteps the issue of how a limited number of shape detectors could identify more than 10,000 smells (and counting) in the human alone. |
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*[[Docking theory of olfaction]] |
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*[[Vibration theory of olfaction]] |
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== References == |
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For more information see: |
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{{Reflist}} |
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* Mori, K. and Shepherd, GM. (1994). Emerging principles of molecular signal processing by mitral/tufted cells in the olfactory bulb. Semin Cell Biol 5-1:65-74. |
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* Burr, Chandler. The Emperor of Scent: A true story of perfume and obsession. Random House, New York: 2002. |
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[[Category:Olfaction]] |
[[Category:Olfaction]] |
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[[Category:Theories]] |
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{{receptor-stub}} |
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Latest revision as of 06:57, 11 December 2023
Odotope theory, also known as weak shape theory,[1] is a theory of how olfactory receptors bind to odor molecules. The theory proposes that a combination of shape factors determine the coupling. The word itself is an analogy to epitopes.
See also
[edit]References
[edit]- ^ "The scent of life. The exquisite complexity of the sense of smell in animals and humans". EMBO Rep. 8 (7): 629–33. July 2007. doi:10.1038/sj.embor.7401029. PMC 1905909. PMID 17603536.
- Mori, K. and Shepherd, GM. (1994). Emerging principles of molecular signal processing by mitral/tufted cells in the olfactory bulb. Semin Cell Biol 5-1:65-74.
- Burr, Chandler. The Emperor of Scent: A true story of perfume and obsession. Random House, New York: 2002.
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