Flavonol 3-sulfotransferase: Difference between revisions
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{{Short description|Class of enzymes}} |
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{{enzyme |
{{infobox enzyme |
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| Name = flavonol 3-sulfotransferase |
| Name = flavonol 3-sulfotransferase |
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| EC_number = 2.8.2.25 |
| EC_number = 2.8.2.25 |
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| CAS_number = 121855-10-5 |
| CAS_number = 121855-10-5 |
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| GO_code = 0047894 |
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| IUBMB_EC_number = 2/8/2/25 |
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In [[enzymology]], a '''flavonol 3-sulfotransferase''' ({{EC number|2.8.2.25}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]] |
In [[enzymology]], a '''flavonol 3-sulfotransferase''' ({{EC number|2.8.2.25}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]] |
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Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and a [[flavonol]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[flavonol 3-sulfate]]. A specific examples of a flavonol that can act as a substrate is [[quercetin]].<ref>{{cite journal | vauthors = Varin L, Ibrahim RK | title = Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from Flaveria chloraefolia | journal = Plant Physiology | volume = 90 | issue = 3 | pages = 977–81 | date = July 1989 | pmid = 16666908 | pmc = 1061831 | doi = 10.1104/pp.90.3.977 }}</ref> |
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and a [[flavonol]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[flavonol 3-sulfate]]. A specific examples of a flavonol that can act as a substrate is [[quercetin]].<ref>{{cite journal | vauthors = Varin L, Ibrahim RK | title = Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from Flaveria chloraefolia | journal = Plant Physiology | volume = 90 | issue = 3 | pages = 977–81 | date = July 1989 | pmid = 16666908 | pmc = 1061831 | doi = 10.1104/pp.90.3.977 }}</ref> |
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This enzyme belongs to the family of [[transferase]]s termed the [[sulfotransferase]]s, which transfer sulfate groups. The [[List of enzymes|systematic name]] of this enzyme class is '''3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase'''. |
This enzyme belongs to the family of [[transferase]]s termed the [[sulfotransferase]]s, which transfer sulfate groups. The [[List of enzymes|systematic name]] of this enzyme class is '''3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase'''. |
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== References == |
== References == |
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{{Sulfur-containing group transferases}} |
{{Sulfur-containing group transferases}} |
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{{Enzymes}} |
{{Enzymes}} |
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{{Portal bar|Biology|border=no}} |
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[[Category:EC 2.8.2]] |
[[Category:EC 2.8.2]] |
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[[Category:Enzymes of unknown structure]] |
[[Category:Enzymes of unknown structure]] |
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Latest revision as of 18:35, 23 January 2024
| flavonol 3-sulfotransferase | |||||||||
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| Identifiers | |||||||||
| EC no. | 2.8.2.25 | ||||||||
| CAS no. | 121855-10-5 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a flavonol 3-sulfotransferase (EC 2.8.2.25) is an enzyme that catalyzes the chemical reaction
- 3'-phosphoadenylyl sulfate + flavonol adenosine 3',5'-bisphosphate + flavonol 3-sulfate
Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and a flavonol, whereas its two products are adenosine 3',5'-bisphosphate and flavonol 3-sulfate. A specific examples of a flavonol that can act as a substrate is quercetin.[1]
This enzyme belongs to the family of transferases termed the sulfotransferases, which transfer sulfate groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:flavonol 3-sulfotransferase.
References
[edit]- ^ Varin L, Ibrahim RK (July 1989). "Partial Purification and Characterization of Three Flavonol-Specific Sulfotransferases from Flaveria chloraefolia". Plant Physiology. 90 (3): 977–81. doi:10.1104/pp.90.3.977. PMC 1061831. PMID 16666908.
