Keratan sulfotransferase: Difference between revisions
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{{Short description|Class of enzymes}} |
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{{infobox enzyme |
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| EC_number = 2.8.2.21 |
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| CAS_number = 62168-79-0 |
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| GO_code = 0045130 |
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In [[enzymology]], a '''keratan sulfotransferase''' ({{EC number|2.8.2.21}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]] |
In [[enzymology]], a '''keratan sulfotransferase''' ({{EC number|2.8.2.21}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]] |
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Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and [[keratan]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[keratan 6'-sulfate]]. |
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and [[keratan]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[keratan 6'-sulfate]]. |
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This enzyme belongs to the family of [[transferase]]s, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is '''3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase'''. Other names in common use include '''3'-phosphoadenylyl keratan sulfotransferase''', '''keratan sulfate sulfotransferase''', and '''3'-phosphoadenylylsulfate:keratan sulfotransferase'''. |
This enzyme belongs to the family of [[transferase]]s, specifically the sulfotransferases, which transfer sulfur-containing groups. The [[List of enzymes|systematic name]] of this enzyme class is '''3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase'''. Other names in common use include '''3'-phosphoadenylyl keratan sulfotransferase''', '''keratan sulfate sulfotransferase''', and '''3'-phosphoadenylylsulfate:keratan sulfotransferase'''. |
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==References== |
==References== |
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{{reflist|1}} |
{{reflist|1}} |
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{{Enzyme references|EC_number=2.8.2.21|IUBMB_EC_number=2/8/2/21}} |
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{{Sulfur-containing group transferases}} |
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==External links== |
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{{Enzymes}} |
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::''The [[CAS registry number]] for this enzyme class is {{CAS registry|62168-79-0}}.'' |
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{{Portal bar|Biology|border=no}} |
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{{Enzyme links|EC_number=2.8.2.21|IUBMB_EC_number=2/8/2/21}} |
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===Gene Ontology (GO) codes=== |
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[[Category:EC 2.8.2]] |
[[Category:EC 2.8.2]] |
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[[Category:Enzymes of unknown structure]] |
[[Category:Enzymes of unknown structure]] |
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Latest revision as of 18:36, 23 January 2024
| keratan sulfotransferase | |||||||||
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| Identifiers | |||||||||
| EC no. | 2.8.2.21 | ||||||||
| CAS no. | 62168-79-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a keratan sulfotransferase (EC 2.8.2.21) is an enzyme that catalyzes the chemical reaction
- 3'-phosphoadenylyl sulfate + keratan adenosine 3',5'-bisphosphate + keratan 6'-sulfate
Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and keratan, whereas its two products are adenosine 3',5'-bisphosphate and keratan 6'-sulfate.
This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase. Other names in common use include 3'-phosphoadenylyl keratan sulfotransferase, keratan sulfate sulfotransferase, and 3'-phosphoadenylylsulfate:keratan sulfotransferase.
References
[edit]- Ruter ER, Kresse H (1984). "Partial purification and characterization of 3'-phosphoadenylylsulfate:keratan sulfate sulfotransferases". J. Biol. Chem. 259 (19): 11771–6. PMID 6592165.
