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{{Short description|Class of enzymes}}
{{enzyme
{{infobox enzyme
| Name = keratan sulfotransferase
| Name = keratan sulfotransferase
| EC_number = 2.8.2.21
| EC_number = 2.8.2.21
| CAS_number = 62168-79-0
| CAS_number = 62168-79-0
| GO_code = 0045130
| IUBMB_EC_number = 2/8/2/21
| GO_code = 0045130
| image =
| image =
| width =
| width =
| caption =
| caption =
}}
}}
In [[enzymology]], a '''keratan sulfotransferase''' ({{EC number|2.8.2.21}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
In [[enzymology]], a '''keratan sulfotransferase''' ({{EC number|2.8.2.21}}) is an [[enzyme]] that [[catalysis|catalyzes]] the [[chemical reaction]]
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Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and [[keratan]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[keratan 6'-sulfate]].
Thus, the two [[substrate (biochemistry)|substrates]] of this enzyme are [[3'-phosphoadenylyl sulfate]] and [[keratan]], whereas its two [[product (chemistry)|products]] are [[adenosine 3',5'-bisphosphate]] and [[keratan 6'-sulfate]].


This enzyme belongs to the family of [[transferase]]s, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is '''3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase'''. Other names in common use include '''3'-phosphoadenylyl keratan sulfotransferase''', '''keratan sulfate sulfotransferase''', and '''3'-phosphoadenylylsulfate:keratan sulfotransferase'''.
This enzyme belongs to the family of [[transferase]]s, specifically the sulfotransferases, which transfer sulfur-containing groups. The [[List of enzymes|systematic name]] of this enzyme class is '''3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase'''. Other names in common use include '''3'-phosphoadenylyl keratan sulfotransferase''', '''keratan sulfate sulfotransferase''', and '''3'-phosphoadenylylsulfate:keratan sulfotransferase'''.


==References==
==References==
{{reflist|1}}
{{reflist|1}}
* {{cite journal | author = Ruter ER, Kresse H | date = 1984 | title = Partial purification and characterization of 3'-phosphoadenylylsulfate:keratan sulfate sulfotransferases | journal = J. Biol. Chem. | volume = 259 | pages = 11771–6 | pmid = 6592165 }}
* {{cite journal |vauthors=Ruter ER, Kresse H | date = 1984 | title = Partial purification and characterization of 3'-phosphoadenylylsulfate:keratan sulfate sulfotransferases | journal = J. Biol. Chem. | volume = 259 | pages = 11771–6 | pmid = 6592165 | issue = 19 }}


{{Sulfur-containing group transferases}}
{{transferase-stub}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}


[[Category:EC 2.8.2]]
[[Category:EC 2.8.2]]
[[Category:Enzymes of unknown structure]]
[[Category:Enzymes of unknown structure]]


{{2.8-enzyme-stub}}

Latest revision as of 18:36, 23 January 2024

keratan sulfotransferase
Identifiers
EC no.2.8.2.21
CAS no.62168-79-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
Search
PMCarticles
PubMedarticles
NCBIproteins

In enzymology, a keratan sulfotransferase (EC 2.8.2.21) is an enzyme that catalyzes the chemical reaction

3'-phosphoadenylyl sulfate + keratan adenosine 3',5'-bisphosphate + keratan 6'-sulfate

Thus, the two substrates of this enzyme are 3'-phosphoadenylyl sulfate and keratan, whereas its two products are adenosine 3',5'-bisphosphate and keratan 6'-sulfate.

This enzyme belongs to the family of transferases, specifically the sulfotransferases, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:keratan 6'-sulfotransferase. Other names in common use include 3'-phosphoadenylyl keratan sulfotransferase, keratan sulfate sulfotransferase, and 3'-phosphoadenylylsulfate:keratan sulfotransferase.

References

[edit]
  • Ruter ER, Kresse H (1984). "Partial purification and characterization of 3'-phosphoadenylylsulfate:keratan sulfate sulfotransferases". J. Biol. Chem. 259 (19): 11771–6. PMID 6592165.