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Molecular Biology: MCB

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What does constitutively dimerizes mean?

I saw it used in a few papers and I'm new to biology. — Preceding unsigned comment added by 68.126.190.60 (talk) 15:20, 29 November 2011 (UTC)[reply]

What probably is meant by "constitutively dimerization" is a protein that dimerizes in the absence of a ligand such as a drug, hormone, peptide, etc. Many proteins such a GPCRs exist as monomers in an inactive state when not bound to a ligand. When a ligand binds to the protein, the protein then dimerizes and the dimer in turn induces some down stream changes in cell function. This type of protein is referred to as "inducible". In contrast, proteins that dimerize and exerts down stream changes in cell function in the absence of ligand is referred to as "constitutive". Boghog (talk) 20:47, 29 November 2011 (UTC)[reply]

Dangling pronoun

are there disulfite bonds in reverse transcriptase, or not? it is not clear what is it example of. — Preceding unsigned comment added by 109.121.83.245 (talk) 19:48, 15 August 2012 (UTC)[reply]

Fixed Thanks for pointing out the ambiguity which I have removed. HIV reverse transcriptase is a heterodimer that is not disulfide link. I add another example (the protein NEMO) that is disulfide linked. Boghog (talk) 21:04, 15 August 2012 (UTC)[reply]

What are the functions of chromosomes

I'm not so sure. 41.114.43.220 (talk) 11:31, 21 July 2022 (UTC)[reply]

Wiki Education assignment: CHEM 378 - Biochemistry Lab - spring 2023

This article was the subject of a Wiki Education Foundation-supported course assignment, between 30 January 2023 and 20 May 2023. Further details are available on the course page. Student editor(s): Ranita12318 (article contribs).

— Assignment last updated by Bubbstar (talk) 20:11, 15 May 2023 (UTC)[reply]

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 == What does constitutively dimerizes mean? ==
 I saw it used in a few papers and I'm new to biology.  <span style="font-size: smaller;" class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/68.126.190.60|68.126.190.60]] ([[User talk:68.126.190.60|talk]]) 15:20, 29 November 2011 (UTC)</span><!-- Template:Unsigned IP --> <!--Autosigned by SineBot-->
+: What probably is meant by "constitutively dimerization" is a protein that dimerizes in the absence of a [[ligand (biochemistry)|ligand]] such as a drug, hormone, peptide, etc.  Many proteins such a [[G protein-coupled receptor|GPCRs]] exist as monomers in an inactive state when not bound to a ligand.  When a ligand binds to the protein, the protein then dimerizes and the dimer in turn induces some down stream changes in cell function.  This type of protein is referred to as "''inducible''".  In contrast, proteins that dimerize and exerts down stream changes in cell function in the absence of ligand is referred to as "''[[constitutive]]''". [[User:Boghog|Boghog]] ([[User talk:Boghog|talk]]) 20:47, 29 November 2011 (UTC)
+==Dangling pronoun==
+are there disulfite bonds in reverse transcriptase, or not? it is not clear what is it example of.  <span style="font-size: smaller;" class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/109.121.83.245|109.121.83.245]] ([[User talk:109.121.83.245|talk]]) 19:48, 15 August 2012 (UTC)</span><!-- Template:Unsigned IP --> <!--Autosigned by SineBot-->
+: {{fixed}} Thanks for pointing out the ambiguity which I have [http://en.wikipedia.org/enwiki/w/index.php?title=Protein_dimer&diff=507589780&oldid=507581331 removed].  HIV reverse transcriptase is a heterodimer that is not disulfide link.  I add another example (the protein [[IKBKG|NEMO]]) that is disulfide linked. [[User:Boghog|Boghog]] ([[User talk:Boghog|talk]]) 21:04, 15 August 2012 (UTC)
+== What are the functions of chromosomes ==
+I'm not so sure. [[Special:Contributions/41.114.43.220|41.114.43.220]] ([[User talk:41.114.43.220|talk]]) 11:31, 21 July 2022 (UTC)
+==Wiki Education assignment: CHEM 378 - Biochemistry Lab - spring 2023==
+{{dashboard.wikiedu.org assignment | course = Wikipedia:Wiki_Ed/Hunter_College,_CUNY/CHEM_378_-_Biochemistry_Lab_-_spring_2023_(Spring_2023) | assignments = [[User:Ranita12318|Ranita12318]] | start_date = 2023-01-30 | end_date = 2023-05-20 }}
+<span class="wikied-assignment" style="font-size:85%;">— Assignment last updated by [[User:Bubbstar|Bubbstar]] ([[User talk:Bubbstar|talk]]) 20:11, 15 May 2023 (UTC)</span>