Talk:Schizophrenia and tobacco smoking: Difference between revisions
the Glial xCT antiporter, glutathione and psychosis |
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==Other approaches== |
==Other approaches== |
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{{cite journal |author=Allen MH, Debanné M, Lazignac C, Adam E, Dickinson LM, Damsa C |title=Effect of Nicotine Replacement Therapy on Agitation in Smokers With Schizophrenia: A Double-Blind, Randomized, Placebo-Controlled Study |journal=Am J Psychiatry |volume= |issue= |pages= |year=2011 |month=January |pmid=21245085 |doi=10.1176/appi.ajp.2010.10040569 |url=}} [[User:Jmh649|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Jmh649|talk]] · [[Special:Contributions/Jmh649|contribs]] · [[Special:EmailUser/Jmh649|email]]) 21:41, 5 March 2011 (UTC) |
{{cite journal |author=Allen MH, Debanné M, Lazignac C, Adam E, Dickinson LM, Damsa C |title=Effect of Nicotine Replacement Therapy on Agitation in Smokers With Schizophrenia: A Double-Blind, Randomized, Placebo-Controlled Study |journal=Am J Psychiatry |volume= |issue= |pages= |year=2011 |month=January |pmid=21245085 |doi=10.1176/appi.ajp.2010.10040569 |url=}} [[User:Jmh649|<span style="color:#0000f1">'''Doc James'''</span>]] ([[User talk:Jmh649|talk]] · [[Special:Contributions/Jmh649|contribs]] · [[Special:EmailUser/Jmh649|email]]) 21:41, 5 March 2011 (UTC) |
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== Causes, what causes? == |
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In its current form ([https://en.wikipedia.org/enwiki/w/index.php?title=Schizophrenia_and_tobacco_smoking&oldid=1019985063 permalink]), I believe the ==Causes== section is problematic, not least because of the highly particular way it's been structured ever since the page was created in 2009 ([https://en.wikipedia.org/enwiki/w/index.php?title=Schizophrenia_and_tobacco_smoking&oldid=332920374 permalink]). Surely it should follow [[WP:MEDRS]] (including [[WP:MEDDATE]]) by presenting current knowledge, rather than a long list of assorted "theories"? There also appears to be an editorial mismatch between title ("Causes") and content (posited explanations for the disproportionate smoking habits). [[Special:Contributions/86.186.120.156|86.186.120.156]] ([[User talk:86.186.120.156|talk]]) 17:54, 26 April 2021 (UTC) |
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Ive wanted to include a mention of a study done in melbourne australia, |
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N-acetylcysteine in psychiatry: current therapeutic |
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evidence and potential mechanisms of action |
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Olivia Dean, BSc, PhD; Frank Giorlando, MBBS, BMedSc; |
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Michael Berk, MBBCh, MMed(Psych), PhD |
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J Psychiatry Neurosci 2011;36(2) |
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== Rather a STRIDENT claim - not sure this should be so. == |
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This well constructed review article looks at 17 or so studies on the use of N-acetyl-cysteine on Schizophrenia, Bipolar disorder, trichotillomania and some other psychiatric diseases including addiction. Importantly the involvement of the glial xCT cysteine glutamate antiporter on the neurotransmitter modulation and the metabotropic glutamate receptor and dopamine release. There is also much evidence that schizophrenics show a marked impairment in methylation which is another role that cysteine plays in the body, as part of the cysteine->SAMe->homocysteine cycle. Perhaps we should study the effects of regularly eating pine/brazil nuts, and beetroot, on mental illness. (betaine, or trimethylglycine is a methyldonor) |
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This is a robust claim - but there are many academic articles that do not use such AFFIRMATIVE language. Chose to soften the language. [[User:BeingObjective|BeingObjective]] ([[User talk:BeingObjective|talk]]) 23:55, 2 November 2023 (UTC) |
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now the fact that smoking and the deposit and accumulation of tar in the lungs obviously puts an enormous strain on the glutathione antioxidant system logically implicates the act of smoking itself, with or without nicotine, might _cause_ schizophrenia. |
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A case of causality - I think this article could mislead - a bunch of theories. |
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i understand that the risks most likely go both ways. that schizophrenia causes smoking as well as smoking causes schizophrenia, and we ought to study the issue to determine both risks. |
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there are many parties that would not like to admit or investigate the significance of this connection but all the same, it must be recognised that faced with the choice between living with schizophrenia and possible remission could ultimately come down to the choice between choosing to give up smoking and to continue. |
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When we look at the other ways in which many societies strongly force patients to undergo therapy and also to prohibit acts/behaviours which are merely believed to increase the risk of developing schizophrenia, possibly only in a predisposed subpopulation, then we must ultimately consider if schizophrenics should be allowed to smoke. I realise there would be significant practical issues with preventing certain individuals from smoking whilst allowing others to continue, but still the significance and impact of such a policy should be investigated, perhaps if only as a voluntary and strongly encouraged treatment. |
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Courts prohibit certain individuals from drinking because of the risk of committing crime, |
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then the same should apply if it can be determined that the risk of committing crime as a result of psychosis caused by the continued depletion of glutathione. But if the governments and NWO really cared about these issues they would ban paracetamol instead of allowing doctors, pharmacies, and advertising to repeatedly tell people how "Safe" paracetamol is, when it in fact is highly dangerous as it causes a serious depletion of glutathione, likely exacerbating virtually any disease. |
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Latest revision as of 06:50, 7 February 2024
 | A fact from Schizophrenia and tobacco smoking appeared on Wikipedia's Main Page in the Did you know column on 28 December 2009 (check views). The text of the entry was as follows:
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Other approaches
[edit]When the main page led me to this article, my immediate first question was whether schizophrenics have similarly high rates of addiction to other addictive substances, and how rates of addiction compared across classes of addictive substances. I see no such research cited here, just a direct focus on possible reasons. Does any such research exist? Is the approach of the article a limitation of the article or of the current research? - Tenebris —Preceding unsigned comment added by 216.254.156.208 (talk) 12:21, 28 December 2009 (UTC)
Interesting study
[edit]Allen MH, Debanné M, Lazignac C, Adam E, Dickinson LM, Damsa C (2011). "Effect of Nicotine Replacement Therapy on Agitation in Smokers With Schizophrenia: A Double-Blind, Randomized, Placebo-Controlled Study". Am J Psychiatry. doi:10.1176/appi.ajp.2010.10040569. PMID 21245085. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link) Doc James (talk · contribs · email) 21:41, 5 March 2011 (UTC)
Causes, what causes?
[edit]In its current form (permalink), I believe the ==Causes== section is problematic, not least because of the highly particular way it's been structured ever since the page was created in 2009 (permalink). Surely it should follow WP:MEDRS (including WP:MEDDATE) by presenting current knowledge, rather than a long list of assorted "theories"? There also appears to be an editorial mismatch between title ("Causes") and content (posited explanations for the disproportionate smoking habits). 86.186.120.156 (talk) 17:54, 26 April 2021 (UTC)
Rather a STRIDENT claim - not sure this should be so.
[edit]This is a robust claim - but there are many academic articles that do not use such AFFIRMATIVE language. Chose to soften the language. BeingObjective (talk) 23:55, 2 November 2023 (UTC)
A case of causality - I think this article could mislead - a bunch of theories.