KIAA0409: Difference between revisions

RRP8
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	2ZFU
Identifiers
Aliases	RRP8, KIAA0409, NML, ribosomal RNA processing 8, methyltransferase, homolog (yeast), ribosomal RNA processing 8
External IDs	OMIM: 615818; MGI: 1914251; HomoloGene: 5621; GeneCards: RRP8; OMA:RRP8 - orthologs
Gene location (Human)
Chr.	Chromosome 11 (human)
End	6,603,616 bp
Gene location (Mouse)
Chr.	Chromosome 7 (mouse)
End	105,386,592 bp
RNA expression pattern
	Top expressed in
	muscle layer of sigmoid colon; ; right lobe of liver; ; gonad; ; mucosa of transverse colon; ; popliteal artery; ; tibial arteries; ; ventricular zone; ; granulocyte; ; body of uterus; ; right auricle;
	Top expressed in
	zygote; ; genital tubercle; ; tail of embryo; ; primitive streak; ; epiblast; ; ureter; ; embryo; ; primary oocyte; ; embryo; ; secondary oocyte;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	methyltransferase activity; transferase activity; S-adenosylmethionine-dependent methyltransferase activity; methylated histone binding; protein binding; RNA binding;
Cellular component	plasma membrane; nucleoplasm; rDNA heterochromatin; chromatin silencing complex; nucleolus; nucleus; cytosol;
Biological process	cellular response to glucose starvation; regulation of transcription, DNA-templated; regulation of transcription by glucose; transcription, DNA-templated; methylation; rDNA heterochromatin assembly; intrinsic apoptotic signaling pathway by p53 class mediator; rRNA processing; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	23378
	101867
	ENSG00000132275
	ENSMUSG00000030888
	O43159
	Q9DB85
	NM_015324
	NM_025897; NM_133951
	NP_056139
	NP_080173; NP_598712
	Wikidata
View/Edit Human	View/Edit Mouse

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Latest revision as of 13:31, 3 April 2024

Ribosomal RNA-processing protein 8 is a protein that in humans is encoded by the RRP8 gene.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000132275 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000030888 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477.
^ "Entrez Gene: KIAA0409 KIAA0409".

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Ribosomal RNA-processing protein 8 (KIAA0409)

This article on a gene on human chromosome 11 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000132275 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000030888 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9455477-5] Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Feb 1998). "Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 4 (5): 307–13. doi:10.1093/dnares/4.5.307. PMID 9455477.

[entrez-6] "Entrez Gene: KIAA0409 KIAA0409".

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[6]

@@ Line 1: / Line 1: @@
+{{Short description|Protein-coding gene in the species Homo sapiens}}
-<!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. -->
+{{cs1 config|name-list-style=vanc}}
-{{PBB_Controls
+{{Lead too short|date=March 2024}}{{Infobox_gene}}
-| update_page = yes
+'''Ribosomal RNA-processing protein 8''' is a [[protein]] that in humans is encoded by the ''RRP8'' [[gene]].<ref name="pmid9455477">{{cite journal |vauthors=Ishikawa K, Nagase T, Nakajima D, Seki N, Ohira M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O | title = Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro | journal = DNA Res | volume = 4 | issue = 5 | pages = 307–13 |date=Feb 1998 | pmid = 9455477 | doi =10.1093/dnares/4.5.307  | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: KIAA0409 KIAA0409| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23378}}</ref>
-| require_manual_inspection = no
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-| update_summary = yes
-| update_citations = yes
-}}
-<!-- The GNF_Protein_box is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{GNF_Protein_box
- | image =
- | image_source =
- | PDB =
- | Name = KIAA0409
- | HGNCid = 29030
- | Symbol = KIAA0409
- | AltSymbols =; RRP8
- | OMIM =
- | ECnumber =
- | Homologene = 5621
- | MGIid = 1914251
- | GeneAtlas_image1 = PBB_GE_KIAA0409_203170_at_tn.png
- | GeneAtlas_image2 = PBB_GE_KIAA0409_203171_s_at_tn.png
- | Function =
- | Component = {{GNF_GO|id=GO:0005634 |text = nucleus}}
- | Process =
- | Orthologs = {{GNF_Ortholog_box
-    | Hs_EntrezGene = 23378
-    | Hs_Ensembl = ENSG00000132275
-    | Hs_RefseqProtein = NP_056139
-    | Hs_RefseqmRNA = NM_015324
-    | Hs_GenLoc_db =
-    | Hs_GenLoc_chr = 11
-    | Hs_GenLoc_start = 6572881
-    | Hs_GenLoc_end = 6581332
-    | Hs_Uniprot = O43159
-    | Mm_EntrezGene = 101867
-    | Mm_Ensembl = ENSMUSG00000030888
-    | Mm_RefseqmRNA = NM_025897
-    | Mm_RefseqProtein = NP_080173
-    | Mm_GenLoc_db =
-    | Mm_GenLoc_chr = 7
-    | Mm_GenLoc_start = 105605835
-    | Mm_GenLoc_end = 105611122
-    | Mm_Uniprot = Q3T9X9
-  }}
-}}
-'''KIAA0409''', also known as '''KIAA0409''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: KIAA0409 KIAA0409| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=23378| accessdate = }}</ref>
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{PBB_Summary
-| section_title =
-| summary_text =
-}}
 ==References==
 {{reflist}}
 ==Further reading==
 {{refbegin | 2}}
+*{{cite journal   |vauthors=Olsen JV, Blagoev B, Gnad F, etal |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |s2cid=7827573 |doi-access=free }}
-{{PBB_Further_reading
+*{{cite journal   |vauthors=Beausoleil SA, Villén J, Gerber SA, etal |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |s2cid=14294292 }}
-| citations =
-*{{cite journal  | author=Olsen JV, Blagoev B, Gnad F, ''et al.'' |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. |journal=Cell |volume=127 |issue= 3 |pages= 635-48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 }}
+*{{cite journal   |vauthors=Nousiainen M, Silljé HH, Sauer G, etal |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391–6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103  | pmc=1459365 |bibcode=2006PNAS..103.5391N |doi-access=free }}
-*{{cite journal  | author=Beausoleil SA, Villén J, Gerber SA, ''et al.'' |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization. |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285-92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 }}
+*{{cite journal   |vauthors=Gerhard DS, Wagner L, Feingold EA, etal |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 }}
-*{{cite journal  | author=Nousiainen M, Silljé HH, Sauer G, ''et al.'' |title=Phosphoproteome analysis of the human mitotic spindle. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=103 |issue= 14 |pages= 5391-6 |year= 2006 |pmid= 16565220 |doi= 10.1073/pnas.0507066103 }}
+*{{cite journal   |vauthors=Strausberg RL, Feingold EA, Grouse LH, etal |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |bibcode=2002PNAS...9916899M |doi-access=free }}
-*{{cite journal  | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
+*{{cite journal   |vauthors=Scherl A, Couté Y, Déon C, etal |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100–9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271  | pmc=133617 }}
-*{{cite journal  | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
+*{{cite journal   |vauthors=Andersen JS, Lyon CE, Fox AH, etal |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1–11 |year= 2002 |pmid= 11790298 |doi=10.1016/S0960-9822(01)00650-9  |s2cid=14132033 |doi-access=free |bibcode=2002CBio...12....1A }}
-*{{cite journal  | author=Scherl A, Couté Y, Déon C, ''et al.'' |title=Functional proteomic analysis of human nucleolus. |journal=Mol. Biol. Cell |volume=13 |issue= 11 |pages= 4100-9 |year= 2003 |pmid= 12429849 |doi= 10.1091/mbc.E02-05-0271 }}
-*{{cite journal  | author=Andersen JS, Lyon CE, Fox AH, ''et al.'' |title=Directed proteomic analysis of the human nucleolus. |journal=Curr. Biol. |volume=12 |issue= 1 |pages= 1-11 |year= 2002 |pmid= 11790298 |doi=  }}
-*{{cite journal  | author=Ishikawa K, Nagase T, Nakajima D, ''et al.'' |title=Prediction of the coding sequences of unidentified human genes. VIII. 78 new cDNA clones from brain which code for large proteins in vitro. |journal=DNA Res. |volume=4 |issue= 5 |pages= 307-13 |year= 1998 |pmid= 9455477 |doi=  }}
-}}
 {{refend}}
+== External links ==
+* [https://www.ebi.ac.uk/pdbe/pdbe-kb/proteins/O43159 PDBe-KB] provides an overview of all the structure information available in the PDB for Human Ribosomal RNA-processing protein 8 (KIAA0409)
+{{KIAA human genes}}
 {{gene-11-stub}}