Zinc transporter ZIP10: Difference between revisions

SLC39A10
Identifiers
Aliases	SLC39A10, LZT-Hs2, solute carrier family 39 member 10
External IDs	OMIM: 608733; MGI: 1914515; HomoloGene: 34076; GeneCards: SLC39A10; OMA:SLC39A10 - orthologs
Gene location (Human)
Chr.	Chromosome 2 (human)
End	195,737,702 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	46,932,012 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; secondary oocyte; ; Brodmann area 46; ; superior frontal gyrus; ; Brodmann area 23; ; germinal epithelium; ; postcentral gyrus; ; right lobe of thyroid gland; ; dorsolateral prefrontal cortex; ; Brodmann area 9;
	Top expressed in
	hand; ; hair follicle; ; otolith organ; ; utricle; ; secondary oocyte; ; primitive streak; ; primary motor cortex; ; cingulate gyrus; ; piriform cortex; ; primary oocyte;
	More reference expression data
	n/a
Gene ontology
Molecular function	metal ion transmembrane transporter activity; zinc ion transmembrane transporter activity;
Cellular component	integral component of membrane; plasma membrane; membrane; integral component of plasma membrane;
Biological process	metal ion transport; negative regulation of B cell apoptotic process; positive regulation of protein tyrosine phosphatase activity; zinc ion transport; ion transport; positive regulation of B cell proliferation; transmembrane transport; cellular zinc ion homeostasis; positive regulation of B cell receptor signaling pathway; zinc ion import across plasma membrane;
	Sources:Amigo / QuickGO
Orthologs
	57181
	227059
	ENSG00000196950
	ENSMUSG00000025986
	Q9ULF5
	Q6P5F6
	NM_001127257; NM_020342
	NM_172653; NM_001356416; NM_001356417
	NP_001120729; NP_065075
	NP_766241; NP_001343345; NP_001343346
	Wikidata
View/Edit Human	View/Edit Mouse

Browse history interactively

← Previous edit

Content deleted Content added

VisualWikitext

Inline

Latest revision as of 20:40, 1 May 2024

Zinc transporter ZIP10, also known as solute carrier family 39 member 10, is a protein that in humans is encoded by the SLC39A10 gene.^[5] ZIP10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters, and have 14 members in the human genome: ZIP1, ZIP2, ZIP3, ZIP4, ZIP5, ZIP6, ZIP7, ZIP8, ZIP9, ZIP10, ZIP11, ZIP12, ZIP13 and ZIP14.^[5]^[6]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000196950 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000025986 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Taylor KM, Morgan HE, Smart K, Zahari NM, Pumford S, Ellis IO, Robertson JF, Nicholson RI (Jul–Aug 2007). "The emerging role of the LIV-1 subfamily of zinc transporters in breast cancer". Mol Med. 13 (7–8): 396–406. doi:10.2119/2007-00040.Taylor. PMC 1936980. PMID 17673939.
^ Eide DJ (February 2004). "The SLC39 family of metal ion transporters". Pflügers Arch. 447 (5): 796–800. doi:10.1007/s00424-003-1074-3. PMID 12748861. S2CID 11765308.

@@ Line 1: / Line 1: @@
+{{Short description|Protein found in humans}}
-{{PBB|geneid=57181}}
+{{Infobox_gene}}
-'''Zinc transporter ZIP10''' is a [[protein]] that in humans is encoded by the ''SLC39A10'' [[gene]].<ref name="pmid17673939">{{cite journal | author = Taylor KM, Morgan HE, Smart K, Zahari NM, Pumford S, Ellis IO, Robertson JF, Nicholson RI | title = The emerging role of the LIV-1 subfamily of zinc transporters in breast cancer | journal = Mol Med | volume = 13 | issue = 7-8 | pages = 396-406 | year = 2007 | month = Jul-Aug | pmid = 17673939 | pmc =  | doi =  }}</ref>
+'''Zinc transporter ZIP10''', also known as '''solute carrier family 39 member 10''', is a [[protein]] that in humans is encoded by the ''SLC39A10'' [[gene]].<ref name="pmid17673939">{{cite journal | vauthors = Taylor KM, Morgan HE, Smart K, Zahari NM, Pumford S, Ellis IO, Robertson JF, Nicholson RI | title = The emerging role of the LIV-1 subfamily of zinc transporters in breast cancer | journal = Mol Med | volume = 13 | issue = 7–8 | pages = 396–406 |date=Jul–Aug 2007 | pmid = 17673939 | pmc =  1936980| doi =  10.2119/2007-00040.Taylor}}</ref> ZIP10 belongs to a subfamily of proteins that show structural characteristics of [[Zinc transporter protein|zinc transporters]], and have 14 members in the human genome: [[SLC39A1|ZIP1]], ZIP2, ZIP3, ZIP4, ZIP5, ZIP6, [[ZIP7]], ZIP8, [[ZIP9]], [[ZIP10]], ZIP11, ZIP12, ZIP13 and ZIP14.<ref name="pmid17673939"/><ref name="pmid12748861">{{cite journal | author = Eide DJ | title = The SLC39 family of metal ion transporters | journal = Pflügers Arch. | volume = 447 | issue = 5 | pages = 796–800 |date=February 2004 | pmid = 12748861 | doi = 10.1007/s00424-003-1074-3 | s2cid = 11765308 }}</ref>
 == References ==
@@ Line 8: / Line 8: @@
 ==Further reading==
 {{refbegin | 2}}
-*{{cite journal  |author=Taylor KM, Nicholson RI |title=The LZT proteins; the LIV-1 subfamily of zinc transporters. |journal=Biochim. Biophys. Acta |volume=1611 |issue= 1-2 |pages= 16-30 |year= 2003 |pmid= 12659941 |doi=  }}
+*{{cite journal   |vauthors=Wang L, McDonnell SK, Hebbring SJ, etal |title=Polymorphisms in mitochondrial genes and prostate cancer risk. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=17 |issue= 12 |pages= 3558–66 |year= 2008 |pmid= 19064571 |doi= 10.1158/1055-9965.EPI-08-0434 |pmc=2750891}}
-*{{cite journal  |author=Wang L, McDonnell SK, Hebbring SJ, ''et al.'' |title=Polymorphisms in mitochondrial genes and prostate cancer risk. |journal=Cancer Epidemiol. Biomarkers Prev. |volume=17 |issue= 12 |pages= 3558-66 |year= 2008 |pmid= 19064571 |doi= 10.1158/1055-9965.EPI-08-0434 }}
 {{refend}}
+{{Membrane transport proteins}}
+[[Category:Solute carrier family]]
+{{gene-2-stub}}
-<!--- Categories --->
-[[Category:Articles created via the Article Wizard]]