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{{Short description|Biophysicist, professor}}
{{Infobox person
{{Infobox scientist
| name = Eva Nogales
| name = Eva Nogales
| image = <!-- just the filename, without the File: or Image: prefix or enclosing [[brackets]] -->
| alt =
| image = Eva Nogales in 2023 06.jpg
| caption =
| alt =
| caption = Nogales in 2023
| birth_name =
| birth_name =
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| birth_date = <!-- {{Birth date and age|YYYY|MM|DD}} or {{Birth-date and age|Month DD, YYYY}} -->
| birth_date = {{Birth-date and age|May 16, 1965}}
| birth_place = [[Madrid, Spain]]
| birth_place = [[Colmenar Viejo]], [[Madrid]], Spain
| death_date = <!-- {{Death date and age|YYYY|MM|DD|YYYY|MM|DD}} or {{Death-date and age|Month DD, YYYY|Month DD, YYYY}} (death date then birth date) -->
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| death_date = <!-- {{Death date and age|YYYY|MM|DD|YYYY|MM|DD}} or {{Death-date and age|Month DD, YYYY|Month DD, YYYY}} (death date then birth date) -->
| death_place =
| nationality =
| death_place =
| other_names =
| nationality =
| ethnicity = <!-- Ethnicity should be supported with a citation from a reliable source -->
| other_names =
| ethnicity = <!-- Ethnicity should be supported with a citation from a reliable source -->
| citizenship =
| citizenship =
| education =
| education =
| alma_mater = [[Bachelor of Science|B.S.]], physics, [[Autonomous University of Madrid]] in 1988, [[Doctor of Philosophy|Ph.D.]], [[University of Keele]], 1992
| alma_mater = [[Bachelor of Science|B.S.]], physics, [[Autonomous University of Madrid]] in 1988, PhD, [[University of Keele]], 1992
| years_active =
| thesis_title =
| thesis_url = https://www.worldcat.org/oclc/{{{OCLC}}}
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| employer = [[University of California, Berkeley]], [[Howard Hughes Medical Institute]], [[Synchrotron Radiation Source]]
| organization =
| thesis_year =
| doctoral_advisor =
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| occupation = [[Biophysicist]], [[professor]]
| years_active =
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| known_for = The first to determine the atomic structure of [[tubulin]] by [[electron crystallography]]
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| workplaces = [[University of California, Berkeley]], [[Howard Hughes Medical Institute]], [[Synchrotron Radiation Source]]
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| spouse = Howard Padmore
| organization =
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| children = Two children
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| occupation = [[Biophysicist]], professor
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| awards = [[Early Career Award]], [[American Society for Cell Biology]] <small>(2005)</small><br>Chabot Science Award for Excellence <small>(2006)</small>
⚫
| known_for = The first to determine the atomic structure of [[tubulin]] by [[electron crystallography]]
⚫
| spouse = Howard Padmore
⚫
| children = 2
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| awards = [[Early Career Award]], [[American Society for Cell Biology]] <small>(2005)</small><br>Chabot Science Award for Excellence <small>(2006)</small><br>[[Shaw Prize]] <small>(2023)</small>
}}
}}


'''Eva Nogales''' (born in Madrid, Spain) is a [[biophysicist]] at the [[Lawrence Berkeley National Laboratory]]. She is head of the Division of Biochemistry, Biophysics and Structural Biology of the Department of Molecular and Cell Biology at the [[University of California, Berkeley]] and a [[Howard Hughes Medical Institute]] investigator.
'''Eva Nogales''' (born in [[Colmenar Viejo]], [[Madrid]], Spain) is a Spanish-American [[biophysicist]] at the [[Lawrence Berkeley National Laboratory]] and a professor at the [[University of California, Berkeley]], where she served as head of the Division of Biochemistry, Biophysics and Structural Biology of the Department of Molecular and Cell Biology (2015–2020). She is a [[Howard Hughes Medical Institute]] investigator.


Nogales is a pioneer in using [[Electron microscope|electron microscopy]] for the structural and functional characterization of macromolecular complexes. She used [[electron crystallography]] to obtain the first structure of [[tubulin]] and identify the binding site of the important anti-cancer drug [[Paclitaxel|taxol]]. She is a leader in combining [[Transmission electron cryomicroscopy|cryo-EM]], computational image analysis and [[Assay|biochemical assays]] to gain insights into function and regulation of biological complexes and [[molecular machine]]s.<ref>{{Cite news|url=https://www.mdtmag.com/news/2016/12/how-see-living-machines|title=How to See Living Machines|date=2016-12-07|work=Medical Design Technology|access-date=2018-02-03}}</ref> Her work has uncovered aspects of cellular function that are relevant to the treatment of cancer and other diseases.<ref>{{Cite web|url=https://www.hhmi.org/scientists/eva-nogales|title=Eva Nogales|website=HHMI.org|language=en|access-date=2019-03-23}}</ref>
Nogales is a pioneer in using [[Electron microscope|electron microscopy]] for the structural and functional characterization of macromolecular complexes. She used [[electron crystallography]] to obtain the first structure of [[tubulin]] and identify the binding site of the important anti-cancer drug [[Paclitaxel|taxol]]. She is a leader in combining [[Transmission electron cryomicroscopy|cryo-EM]], computational image analysis and [[Assay|biochemical assays]] to gain insights into function and regulation of biological complexes and [[molecular machine]]s.<ref>{{Cite news|url=https://www.mdtmag.com/news/2016/12/how-see-living-machines|title=How to See Living Machines|date=2016-12-07|work=Medical Design Technology|access-date=2018-02-03}}</ref> Her work has uncovered aspects of cellular function that are relevant to the treatment of cancer and other diseases.<ref>{{Cite web|url=https://www.hhmi.org/scientists/eva-nogales|title=Eva Nogales|website=HHMI.org|language=en|access-date=2019-03-23}}</ref>


==Early life and education==
==Early life and education==
Eva Nogales obtained her [[Bachelor of Science|B.S.]] degree in physics from the [[Autonomous University of Madrid]] in 1988. She later earned her [[Doctor of Philosophy|Ph.D.]] from the [[University of Keele]] in 1992 while working at the [[Synchrotron Radiation Source]] under the supervision of [[Joan Bordas]].
Eva Nogales obtained her BS degree in physics from the [[Autonomous University of Madrid]] in 1988.<ref name=":0">{{Cite web |title=Nogales Lab – CryoEM – Publications |url=http://cryoem.berkeley.edu/eva.html |access-date=2022-03-16 |website=cryoem.berkeley.edu |archive-date=2021-12-25 |archive-url=https://web.archive.org/web/20211225201816/http://cryoem.berkeley.edu/eva.html |url-status=dead }}</ref> She later earned her PhD from the [[University of Keele]] in 1992 while working at the [[Synchrotron Radiation Source]] under the supervision of [[Joan Bordas]].<ref name=":0" />


==Career==
==Career==
During her post-doctoral work in the laboratory of Ken Downing at [[Keele University]], Eva Nogales was the first to determine the atomic structure of [[tubulin]] and the location of the taxol-binding site by [[electron crystallography]].<ref>{{Cite journal|last=Nogales|first=E.|last2=Wolf|first2=S. G.|last3=Khan|first3=I. A.|last4=Ludueña|first4=R. F.|last5=Downing|first5=K. H.|date=1995-06-01|title=Structure of tubulin at 6.5 A and location of the taxol-binding site|journal=Nature|volume=375|issue=6530|pages=424–427|doi=10.1038/375424a0|issn=0028-0836|pmid=7760939|bibcode=1995Natur.375..424N}}</ref><ref>Nogales, E., Wolf, S. G. and Downing, K. H. (1998.) Structure of the ab tubulin dimer by electron crystallography. ''Nature'', 391, 199-203.</ref><ref>{{Cite journal|last=Nogales|first=E.|last2=Whittaker|first2=M.|last3=Milligan|first3=R. A.|last4=Downing|first4=K. H.|date=1999-01-08|title=High-resolution model of the microtubule|journal=Cell|volume=96|issue=1|pages=79–88|issn=0092-8674|pmid=9989499|doi=10.1016/s0092-8674(00)80961-7}}</ref> She joined [[Lawrence Berkeley National Laboratory]] as a staff scientist in 1995 and became an assistant professor in the Department of Molecular and Cell Biology at the [[University of California, Berkeley]] in 1998. In 2000 she became an investigator in the [[Howard Hughes Medical Institute]]. As [[Transmission electron cryomicroscopy|cryo-EM]] techniques became more powerful,<ref>{{Cite journal|last=Callaway|first=Ewen|date=2015-09-10|title=The revolution will not be crystallized: a new method sweeps through structural biology|journal=Nature|volume=525|issue=7568|pages=172–174|doi=10.1038/525172a|issn=1476-4687|pmid=26354465|bibcode=2015Natur.525..172C|doi-access=free}}</ref> she became a leader in applying cryo-EM to the study of microtubule structure and function<ref>{{Cite journal|last=Downing|first=Kenneth H.|last2=Nogales|first2=Eva|date=2010|title=Cryoelectron microscopy applications in the study of tubulin structure, microtubule architecture, dynamics and assemblies, and interaction of microtubules with motors|journal=Methods in Enzymology|volume=483|pages=121–142|doi=10.1016/S0076-6879(10)83006-X|issn=1557-7988|pmc=4165512|pmid=20888472|isbn=9780123849939}}</ref> and other large [[macromolecular assemblies]] such as [[eukaryotic transcription]] and translation initiation complexes<ref>Michael A. Cianfrocco, George A. Kassavetis, Patricia Grob, Jie Fang, Tamar Juven-Gershon, James T. Kadonaga, Eva Nogales (2013.) Human TFIID Binds to Core Promoter DNA in a Reorganized Structural State. ''Cell'', 152(1):120-131.</ref><ref>{{Cite web|url=https://www.genengnews.com/news/stop-motion-view-of-dna-binding-complex-may-animate-drug-discovery/|title=Stop-Motion View of DNA-Binding Complex May Animate Drug Discovery|date=2018-11-20|website=GEN - Genetic Engineering and Biotechnology News|language=en-US|access-date=2019-03-23}}</ref> and [[telomerase]].<ref>{{Cite web|url=https://www.technologynetworks.com/drug-discovery/articles/the-3d-structure-of-telomerase-uncovering-its-role-in-human-disease-300278|title=The 3D Structure of Telomerase: Uncovering Its Role in Human Disease|website=Drug Discovery from Technology Networks|language=en|access-date=2019-03-23}}</ref>
During her post-doctoral work in the laboratory of Ken Downing at the [[Lawrence Berkeley National Laboratory]], Eva Nogales was the first to determine the atomic structure of [[tubulin]] and the location of the taxol-binding site by [[electron crystallography]].<ref>{{Cite journal|last1=Nogales|first1=E.|last2=Wolf|first2=S. G.|last3=Khan|first3=I. A.|last4=Ludueña|first4=R. F.|last5=Downing|first5=K. H.|date=1995-06-01|title=Structure of tubulin at 6.5 A and location of the taxol-binding site|journal=Nature|volume=375|issue=6530|pages=424–427|doi=10.1038/375424a0|issn=0028-0836|pmid=7760939|bibcode=1995Natur.375..424N|s2cid=4338992}}</ref><ref>Nogales, E., Wolf, S. G. and Downing, K. H. (1998.) Structure of the ab tubulin dimer by electron crystallography. ''Nature'', 391, 199-203.</ref><ref>{{Cite journal|last1=Nogales|first1=E.|last2=Whittaker|first2=M.|last3=Milligan|first3=R. A.|last4=Downing|first4=K. H.|date=1999-01-08|title=High-resolution model of the microtubule|journal=Cell|volume=96|issue=1|pages=79–88|issn=0092-8674|pmid=9989499|doi=10.1016/s0092-8674(00)80961-7|s2cid=18422680|doi-access=free}}</ref> She became an assistant professor in the Department of Molecular and Cell Biology at the [[University of California, Berkeley]] in 1998. In 2000 she became an investigator in the [[Howard Hughes Medical Institute]]. As [[Transmission electron cryomicroscopy|cryo-EM]] techniques became more powerful,<ref>{{Cite journal|last=Callaway|first=Ewen|date=2015-09-10|title=The revolution will not be crystallized: a new method sweeps through structural biology|journal=Nature|volume=525|issue=7568|pages=172–174|doi=10.1038/525172a|issn=1476-4687|pmid=26354465|bibcode=2015Natur.525..172C|doi-access=free}}</ref> she became a leader in applying cryo-EM to the study of microtubule structure and function<ref>{{Cite book|last1=Downing|first1=Kenneth H.|last2=Nogales|first2=Eva|chapter=Cryoelectron Microscopy Applications in the Study of Tubulin Structure, Microtubule Architecture, Dynamics and Assemblies, and Interaction of Microtubules with Motors |date=2010|title=Cryo-EM, Part C: Analyses, Interpretation, and Case studies|series=Methods in Enzymology|volume=483|pages=121–142|doi=10.1016/S0076-6879(10)83006-X|issn=1557-7988|pmc=4165512|pmid=20888472|isbn=9780123849939}}</ref> and other large [[macromolecular assemblies]] such as [[eukaryotic transcription]] and translation initiation complexes,<ref>Michael A. Cianfrocco, George A. Kassavetis, Patricia Grob, Jie Fang, Tamar Juven-Gershon, James T. Kadonaga, Eva Nogales (2013.) Human TFIID Binds to Core Promoter DNA in a Reorganized Structural State. ''Cell'', 152(1):120–131.</ref><ref>{{Cite web|url=https://www.genengnews.com/news/stop-motion-view-of-dna-binding-complex-may-animate-drug-discovery/|title=Stop-Motion View of DNA-Binding Complex May Animate Drug Discovery|date=2018-11-20|website=GEN – Genetic Engineering and Biotechnology News|language=en-US|access-date=2019-03-23}}</ref> the polycomb complex PRC2, and [[telomerase]].<ref>{{Cite web|url=https://www.technologynetworks.com/drug-discovery/articles/the-3d-structure-of-telomerase-uncovering-its-role-in-human-disease-300278|title=The 3D Structure of Telomerase: Uncovering Its Role in Human Disease|website=Drug Discovery from Technology Networks|language=en|access-date=2019-03-23}}</ref>

==Selected publications==
*{{cite journal |last1=Nogales |first1=Eva |last2=Whittaker |first2=Michael |last3=Milligan |first3=Ronald A. |last4=Downing |first4=Kenneth H. |title=High-Resolution Model of the Microtubule |journal=Cell |date=January 1999 |volume=96 |issue=1 |pages=79–88 |doi=10.1016/s0092-8674(00)80961-7 |pmid=9989499 |issn=0092-8674|doi-access=free }}
*{{cite journal |last1=Löwe |first1=J |last2=Li |first2=H |last3=Downing |first3=K. H |last4=Nogales |first4=E |title=Refined structure of αβ-tubulin at 3.5 Å resolution11Edited by I. A. Wilson |journal=Journal of Molecular Biology |date=9 November 2001 |volume=313 |issue=5 |pages=1045–1057 |doi=10.1006/jmbi.2001.5077 |pmid=11700061 |url=https://doi.org/10.1006/jmbi.2001.5077 |language=en |issn=0022-2836}}
*{{cite journal |last1=Nogales |first1=Eva |title=Structural Insights into Microtubule Function |journal=Annual Review of Biophysics and Biomolecular Structure |date=1 June 2001 |volume=30 |issue=1 |pages=397–420 |doi=10.1146/annurev.biophys.30.1.397 |pmid=11441808 |url=https://doi.org/10.1146/annurev.biophys.30.1.397 |issn=1056-8700}}


==Awards==
==Awards==
* 2000: investigator, [[Howard Hughes Medical Institute]]
* 2000: investigator, [[Howard Hughes Medical Institute]]
*2005: Early Career Life Scientist Award, [[American Society for Cell Biology]]<ref>{{Cite web|url=https://www.ascb.org/award/early-career-life-scientist-award/|title=Early Career Life Scientist Award|website=ASCB|language=en-US|access-date=2019-03-23}}</ref>
* 2005: Early Career Life Scientist Award, [[American Society for Cell Biology]]<ref>{{Cite web|url=https://www.ascb.org/award/early-career-life-scientist-award/|title=Early Career Life Scientist Award|website=ASCB|language=en-US|access-date=2019-03-23}}</ref>
* 2006: Chabot Science Award for Excellence
* 2006: Chabot Science Award for Excellence
*2015: Dorothy Crowfoot Hodgkin Award, [[Protein Society]]<ref>{{Cite web|url=http://www.eurekalert.org/pub_releases/2015-02/tps-atw020415.php|title=Announcing the winners of the 2015 Protein Society Awards|website=EurekAlert!|language=en|access-date=2019-03-23}}</ref>
* 2015: Dorothy Crowfoot Hodgkin Award, [[Protein Society]]<ref>{{Cite web|url=http://www.eurekalert.org/pub_releases/2015-02/tps-atw020415.php|title=Announcing the winners of the 2015 Protein Society Awards|website=EurekAlert!|language=en|access-date=2019-03-23}}</ref>
* 2015: Elected as a member of the US [[National Academy of Sciences]]
* 2015: Elected as a member of the US [[National Academy of Sciences]]<ref name="nasonline.org 2021 r165">{{cite web | title=Eva Nogales | website=nasonline.org | date=16 April 2021 | url=https://www.nasonline.org/member-directory/members/20035992.html | access-date=29 December 2023}}</ref>
*2016: Elected to the [[American Academy of Arts and Sciences]]<ref>{{Cite news|url=http://www.dailycal.org/2016/04/22/9-campus-faculty-selected-membership-american-academy-arts-sciences/|title=9 campus faculty selected for membership in American Academy of Arts and Sciences {{!}} The Daily Californian|date=2016-04-22|work=The Daily Californian|access-date=2018-02-03|language=en-US}}</ref>
* 2016: Elected to the [[American Academy of Arts and Sciences]]<ref>{{Cite news|url=http://www.dailycal.org/2016/04/22/9-campus-faculty-selected-membership-american-academy-arts-sciences/|title=9 campus faculty selected for membership in American Academy of Arts and Sciences {{!}} The Daily Californian|date=2016-04-22|work=The Daily Californian|access-date=2018-02-03|language=en-US}}</ref>
*2018: [[WICB Junior and Senior Awards|Women in Cell Biology Award (Senior)]], [[American Society for Cell Biology]]<ref>{{Cite web|url=https://www.ascb.org/award/women-in-cell-biology-awards/|title=Women in Cell Biology Awards|website=ASCB|language=en-US|access-date=2019-03-23}}</ref>
* 2018: [[WICB Junior and Senior Awards|Women in Cell Biology Award (Senior)]], [[American Society for Cell Biology]]<ref>{{Cite web|url=https://www.ascb.org/award/women-in-cell-biology-awards/|title=Women in Cell Biology Awards|website=ASCB|language=en-US|access-date=2019-03-23}}</ref>
* 2019: Grimwade Medal for Biochemistry.<ref>{{Cite web|url=http://biosciences.lbl.gov/2019/03/07/nogales-receives-2019-grimwade-medal/|title=Nogales Receives 2019 Grimwade Medal|date=2019-03-07|website=Biosciences Area|language=en-US|access-date=2019-03-23}}</ref>
* 2019: Grimwade Medal for Biochemistry.<ref>{{Cite web|url=http://biosciences.lbl.gov/2019/03/07/nogales-receives-2019-grimwade-medal/|title=Nogales Receives 2019 Grimwade Medal|date=2019-03-07|website=Biosciences Area|language=en-US|access-date=2019-03-23}}</ref>
* 2021: [[AAAS Fellow]]s Award.<ref>{{Cite web |title=AAAS Honors Outstanding Scientific Contributors as 2021 AAAS Fellows {{!}} American Association for the Advancement of Science |url=https://www.aaas.org/news/aaas-honors-outstanding-scientific-contributors-2021-aaas-fellows |access-date=2022-03-16 |website=www.aaas.org |language=en}}</ref>
* 2023: [[Shaw Prize]] in Life Sciences.<ref>[https://www.shawprize.org/news/announcement-press-conference-2023-press-release Shaw Prize 2023]</ref>


==Personal life==
==Personal life==
Nogales is married to Howard Padmore and they have two children.
Nogales is married to Howard Padmore and they have two children.<ref name="Phelan 2014 q953">{{cite web | last=Phelan | first=Laura | title=Eva Nogales | website=The [[Biophysical Society]] | date=1 December 2014 | url=https://www.biophysics.org/profiles/eva-nogales | access-date=29 December 2023}}</ref>


==References==
==References==
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* [http://cryoem.berkeley.edu/ Nogales lab]
* [http://cryoem.berkeley.edu/ Nogales lab]


{{Shaw Prize laureates}}
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[[Category:Molecular biologists]]
[[Category:Spanish biophysicists]]
[[Category:Spanish biophysicists]]
[[Category:Women biophysicists]]
[[Category:Biophysicists]]
[[Category:Spanish emigrants to the United States]]
[[Category:Spanish emigrants to the United States]]
[[Category:University of California, Berkeley faculty]]
[[Category:University of California, Berkeley faculty]]
[[Category:Women biologists]]
[[Category:American women biologists]]
[[Category:Year of birth missing (living people)]]
[[Category:American women scientists]]
[[Category:21st-century American women scientists]]
[[Category:21st-century American women scientists]]
[[Category:Members of the United States National Academy of Sciences]]
[[Category:Members of the United States National Academy of Sciences]]
[[Category:Alumni of Keele University]]

[[Category:Autonomous University of Madrid alumni]]

[[Category:Structural biologists]]
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{{Biologist-stub}}

Latest revision as of 01:31, 22 June 2024

Eva Nogales
Nogales in 2023
BornMay 16, 1965 (1965-05-16) (age 59)
Colmenar Viejo, Madrid, Spain
Alma materB.S., physics, Autonomous University of Madrid in 1988, PhD, University of Keele, 1992
Occupation(s)Biophysicist, professor
Known forThe first to determine the atomic structure of tubulin by electron crystallography
SpouseHoward Padmore
Children2
AwardsEarly Career Award, American Society for Cell Biology (2005)
Chabot Science Award for Excellence (2006)
Shaw Prize (2023)
Scientific career
InstitutionsUniversity of California, Berkeley, Howard Hughes Medical Institute, Synchrotron Radiation Source

Eva Nogales (born in Colmenar Viejo, Madrid, Spain) is a Spanish-American biophysicist at the Lawrence Berkeley National Laboratory and a professor at the University of California, Berkeley, where she served as head of the Division of Biochemistry, Biophysics and Structural Biology of the Department of Molecular and Cell Biology (2015–2020). She is a Howard Hughes Medical Institute investigator.

Nogales is a pioneer in using electron microscopy for the structural and functional characterization of macromolecular complexes. She used electron crystallography to obtain the first structure of tubulin and identify the binding site of the important anti-cancer drug taxol. She is a leader in combining cryo-EM, computational image analysis and biochemical assays to gain insights into function and regulation of biological complexes and molecular machines.[1] Her work has uncovered aspects of cellular function that are relevant to the treatment of cancer and other diseases.[2]

Early life and education

[edit]

Eva Nogales obtained her BS degree in physics from the Autonomous University of Madrid in 1988.[3] She later earned her PhD from the University of Keele in 1992 while working at the Synchrotron Radiation Source under the supervision of Joan Bordas.[3]

Career

[edit]

During her post-doctoral work in the laboratory of Ken Downing at the Lawrence Berkeley National Laboratory, Eva Nogales was the first to determine the atomic structure of tubulin and the location of the taxol-binding site by electron crystallography.[4][5][6] She became an assistant professor in the Department of Molecular and Cell Biology at the University of California, Berkeley in 1998. In 2000 she became an investigator in the Howard Hughes Medical Institute. As cryo-EM techniques became more powerful,[7] she became a leader in applying cryo-EM to the study of microtubule structure and function[8] and other large macromolecular assemblies such as eukaryotic transcription and translation initiation complexes,[9][10] the polycomb complex PRC2, and telomerase.[11]

Selected publications

[edit]
  • Nogales, Eva; Whittaker, Michael; Milligan, Ronald A.; Downing, Kenneth H. (January 1999). "High-Resolution Model of the Microtubule". Cell. 96 (1): 79–88. doi:10.1016/s0092-8674(00)80961-7. ISSN 0092-8674. PMID 9989499.
  • Löwe, J; Li, H; Downing, K. H; Nogales, E (9 November 2001). "Refined structure of αβ-tubulin at 3.5 Å resolution11Edited by I. A. Wilson". Journal of Molecular Biology. 313 (5): 1045–1057. doi:10.1006/jmbi.2001.5077. ISSN 0022-2836. PMID 11700061.
  • Nogales, Eva (1 June 2001). "Structural Insights into Microtubule Function". Annual Review of Biophysics and Biomolecular Structure. 30 (1): 397–420. doi:10.1146/annurev.biophys.30.1.397. ISSN 1056-8700. PMID 11441808.

Awards

[edit]

Personal life

[edit]

Nogales is married to Howard Padmore and they have two children.[20]

References

[edit]
  1. ^ "How to See Living Machines". Medical Design Technology. 2016-12-07. Retrieved 2018-02-03.
  2. ^ "Eva Nogales". HHMI.org. Retrieved 2019-03-23.
  3. ^ a b "Nogales Lab – CryoEM – Publications". cryoem.berkeley.edu. Archived from the original on 2021-12-25. Retrieved 2022-03-16.
  4. ^ Nogales, E.; Wolf, S. G.; Khan, I. A.; Ludueña, R. F.; Downing, K. H. (1995-06-01). "Structure of tubulin at 6.5 A and location of the taxol-binding site". Nature. 375 (6530): 424–427. Bibcode:1995Natur.375..424N. doi:10.1038/375424a0. ISSN 0028-0836. PMID 7760939. S2CID 4338992.
  5. ^ Nogales, E., Wolf, S. G. and Downing, K. H. (1998.) Structure of the ab tubulin dimer by electron crystallography. Nature, 391, 199-203.
  6. ^ Nogales, E.; Whittaker, M.; Milligan, R. A.; Downing, K. H. (1999-01-08). "High-resolution model of the microtubule". Cell. 96 (1): 79–88. doi:10.1016/s0092-8674(00)80961-7. ISSN 0092-8674. PMID 9989499. S2CID 18422680.
  7. ^ Callaway, Ewen (2015-09-10). "The revolution will not be crystallized: a new method sweeps through structural biology". Nature. 525 (7568): 172–174. Bibcode:2015Natur.525..172C. doi:10.1038/525172a. ISSN 1476-4687. PMID 26354465.
  8. ^ Downing, Kenneth H.; Nogales, Eva (2010). "Cryoelectron Microscopy Applications in the Study of Tubulin Structure, Microtubule Architecture, Dynamics and Assemblies, and Interaction of Microtubules with Motors". Cryo-EM, Part C: Analyses, Interpretation, and Case studies. Methods in Enzymology. Vol. 483. pp. 121–142. doi:10.1016/S0076-6879(10)83006-X. ISBN 9780123849939. ISSN 1557-7988. PMC 4165512. PMID 20888472.
  9. ^ Michael A. Cianfrocco, George A. Kassavetis, Patricia Grob, Jie Fang, Tamar Juven-Gershon, James T. Kadonaga, Eva Nogales (2013.) Human TFIID Binds to Core Promoter DNA in a Reorganized Structural State. Cell, 152(1):120–131.
  10. ^ "Stop-Motion View of DNA-Binding Complex May Animate Drug Discovery". GEN – Genetic Engineering and Biotechnology News. 2018-11-20. Retrieved 2019-03-23.
  11. ^ "The 3D Structure of Telomerase: Uncovering Its Role in Human Disease". Drug Discovery from Technology Networks. Retrieved 2019-03-23.
  12. ^ "Early Career Life Scientist Award". ASCB. Retrieved 2019-03-23.
  13. ^ "Announcing the winners of the 2015 Protein Society Awards". EurekAlert!. Retrieved 2019-03-23.
  14. ^ "Eva Nogales". nasonline.org. 16 April 2021. Retrieved 29 December 2023.
  15. ^ "9 campus faculty selected for membership in American Academy of Arts and Sciences | The Daily Californian". The Daily Californian. 2016-04-22. Retrieved 2018-02-03.
  16. ^ "Women in Cell Biology Awards". ASCB. Retrieved 2019-03-23.
  17. ^ "Nogales Receives 2019 Grimwade Medal". Biosciences Area. 2019-03-07. Retrieved 2019-03-23.
  18. ^ "AAAS Honors Outstanding Scientific Contributors as 2021 AAAS Fellows | American Association for the Advancement of Science". www.aaas.org. Retrieved 2022-03-16.
  19. ^ Shaw Prize 2023
  20. ^ Phelan, Laura (1 December 2014). "Eva Nogales". The Biophysical Society. Retrieved 29 December 2023.
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