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{{More citations needed|date=November 2019}}
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'''Northfield Laboratories Inc.''' ({{nasdaq|NFLD}}) was the maker of [[PolyHeme]], a [[hemoglobin]]-based oxygen carrier (HBOC). The company is based in [[Evanston, Illinois]], with Dr. Steven A. Gould as its [[Chief Executive Officer]]. As of [[May 31]], [[2005]], the company had 68 employees.
{{Infobox company
It was founded in [[1985]] and has since been a mainly [[Research and Development]] company. Northfield's only product was [[PolyHeme]], an oxygen-carrying [[blood substitute]], which failed to receive [[Food and Drug Administration|FDA]] regulatory approval. On May 9, 2009, after being informed by the [[Food and Drug Administration|FDA]] the product's risks outweighed the benefits, the company shut down operations. During their operations, they incurred losses of about 220 million dollars.<ref>http://www.chicagotribune.com/business/chi-sat-northfield-0509-may09,0,1111961.story, retrieved May 9, 2009</ref>
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'''Northfield Laboratories Inc.''' (former NASDAQ: '''NFLD''') was the maker of [[PolyHeme]], a [[Hemoglobin-based oxygen carriers|hemoglobin-based oxygen carrier]] (HBOC). The company was based in [[Evanston, Illinois]], with Dr. Steven A. Gould as its [[chief executive officer]]. As of May 31, 2005, the company had 68 employees.

It was founded in 1985 and has since been a mainly [[research and development]] company. Northfield's only product was PolyHeme, an oxygen-carrying [[blood substitute]], which failed to receive [[Food and Drug Administration]] (FDA) regulatory approval. On May 9, 2009, after being informed by the FDA the product's risks outweighed the benefits, the company shut down operations. During their operations, they incurred losses of about 220 million dollars.<ref>{{cite web |url=http://www.chicagotribune.com/business/chi-sat-northfield-0509-may09,0,1111961.story |title=Northfield Labs shuts operations |website=www.chicagotribune.com |access-date=May 9, 2009 |archive-date=May 12, 2009 |archive-url=https://web.archive.org/web/20090512103530/http://www.chicagotribune.com/business/chi-sat-northfield-0509-may09,0,1111961.story |url-status=live }}</ref> The corporation was also criticized for some design elements of its clinical trials related to the need to perform critical care and resuscitation while patients were in grave clinical conditions due to the mechanisms of injury incurred and the consequent inability of patients to provide informed consent for treatment.<ref>{{cite web |last1=Rhee |first1=Joseph |title=Test of Controversial Artificial Blood Product a Failure |url=http://blogs.abcnews.com/theblotter/2007/05/test_of_controv.html |website=ABCNews |archive-url=https://web.archive.org/web/20071218222258/http://blogs.abcnews.com/theblotter/2007/05/test_of_controv.html |archive-date=December 18, 2007 |date=May 23, 2007 |url-status=dead}}</ref>


==See also==
==See also==
* [[PolyHeme]]
* [[Blood substitutes]]
* [[Clinical trial]]
* [[Clinical trial]]
* [[Urgent care]]
* [[Urgent care]]
* [[Unethical Human Experimentation in the United States]]


==External links==
==References==
{{Reflist}}


==External links==
* [http://www.northfieldlabs.com/ Official website of the maker of PolyHeme, Northfield Laboratories.]
* [http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=6914127&OS=6914127&RS=6914127 PolyHeme's patent.]
* [http://patft.uspto.gov/netacgi/nph-Parser?Sect1=PTO2&Sect2=HITOFF&p=1&u=%2Fnetahtml%2FPTO%2Fsearch-bool.html&r=1&f=G&l=50&co1=AND&d=PTXT&s1=6914127&OS=6914127&RS=6914127 PolyHeme's patent.]


{{Authority control}}
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[[Category:Chemical companies]]

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[[Category:Chemical companies of the United States]]
[[Category:Transfusion medicine]]
[[Category:Transfusion medicine]]
[[Category:Evanston, Illinois]]
[[Category:Companies formerly listed on the Nasdaq]]
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[[Category:Companies based in Evanston, Illinois]]




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{{chemical-company-stub}}
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[[Category:Companies in the NASDAQ Biotechnology Index]]

Latest revision as of 21:50, 11 July 2024

Northfield Laboratories Inc.
Founded1985
DefunctMay 9, 2009 (2009-05-09)
Headquarters
Evanston, Illinois
ProductsPolyHeme

Northfield Laboratories Inc. (former NASDAQ: NFLD) was the maker of PolyHeme, a hemoglobin-based oxygen carrier (HBOC). The company was based in Evanston, Illinois, with Dr. Steven A. Gould as its chief executive officer. As of May 31, 2005, the company had 68 employees.

It was founded in 1985 and has since been a mainly research and development company. Northfield's only product was PolyHeme, an oxygen-carrying blood substitute, which failed to receive Food and Drug Administration (FDA) regulatory approval. On May 9, 2009, after being informed by the FDA the product's risks outweighed the benefits, the company shut down operations. During their operations, they incurred losses of about 220 million dollars.[1] The corporation was also criticized for some design elements of its clinical trials related to the need to perform critical care and resuscitation while patients were in grave clinical conditions due to the mechanisms of injury incurred and the consequent inability of patients to provide informed consent for treatment.[2]

See also

[edit]

References

[edit]
  1. ^ "Northfield Labs shuts operations". www.chicagotribune.com. Archived from the original on May 12, 2009. Retrieved May 9, 2009.
  2. ^ Rhee, Joseph (May 23, 2007). "Test of Controversial Artificial Blood Product a Failure". ABCNews. Archived from the original on December 18, 2007.
[edit]


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