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{{short description|French molecular biologist}}
{{BLP sources|date=February 2013}}
{{Infobox scientist
{{Infobox scientist
|name = Pierre Chambon
|name = Pierre Chambon
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|residence =
|residence =
|citizenship =
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|nationality = [[France]]
|nationality = French
|ethnicity =
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|field =
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|influences =
|influences =
|influenced =
|influenced =
|prizes = [[Richard Lounsbery Award]] {{small|(1982)}}<br>[[Harvey Prize]] {{small|(1987)}}<br>[[Louis-Jeantet Prize for Medicine]] (1991)<ref>[https://www.jeantet.ch/en/prix-louis-jeantet/laureats/1990-en/professeur-pierre-chambon/ Louis-Jeantet Prize]</ref><br>[[Sir Hans Krebs Medal]] {{small|(1990)}}<br>[[Welch Award in Chemistry]] {{small|(1998)}}<br>[[Louisa Gross Horwitz Prize]] {{small|(1999)}}<br>[[Albert Lasker Award for Basic Medical Research]]<br>[[Alfred P. Sloan, Jr. Prize]] <small>(2003)</small><br>[[Gairdner Foundation International Award]] <small>(2010)</small>
|prizes = [[Richard Lounsbery Award]] {{small|(1982)}}<br>[[Harvey Prize]] {{small|(1987)}}<br>[[Sir Hans Krebs Medal]] {{small|(1990)}}<br>[[Louis-Jeantet Prize for Medicine]] {{small|(1991)}}<ref>{{Cite web |date=2017-10-01 |title=Professor Pierre CHAMBON {{!}} Jeantet |url=https://www.jeantet.ch/en/prix-louis-jeantet/laureats/1991-en/professeur-pierre-chambon/ |access-date=2023-08-11 |language=en-US}}</ref><br>[[Welch Award in Chemistry]] {{small|(1998)}}<br>[[Louisa Gross Horwitz Prize]] {{small|(1999)}}<br>[[Albert Lasker Award for Basic Medical Research]] {{small|(2004)}}<br>[[Alfred P. Sloan, Jr. Prize]] <small>(2003)</small><br>[[Gairdner Foundation International Award]] <small>(2010)</small>
<br>[[Louisa Gross Horwitz Prize]] <small>(2018)</small>
|religion =
|religion =
|signature =
|signature =
}}
}}
'''Pierre Chambon''' (born 7 February 1931 in [[Mulhouse, France]]) was the founder of the {{Interlanguage link multi|Institute for Genetics and Cellular and Molecular Biology|fr|3=Institut de génétique et de biologie moléculaire et cellulaire}} in [[Strasbourg]], [[France]].<ref>{{Cite web|url=http://www.usias.fr/en/chairs/pierre-chambon/|title=Pierre Chambon - USIAS - University of Strasbourg|website=www.usias.fr|language=fr-FR|access-date=2018-04-30}}</ref> He was one of the leading molecular biologists who utilized gene cloning and sequencing technology to first decipher the structure of eukaryotic genes and their modes of regulation. His major contributions to science include the identification of RNA polymerase II(B){{ref|a}}, the identification of transcriptional control elements, the cloning and dissection of [[nuclear hormone receptor]]s, revealing their structure and showing how they contribute to human [[physiology]]. He accomplished much of his work in the 1970-90s.
'''Pierre Chambon''' ({{IPA|fr|pjɛʁ ʃɑ̃bɔ̃}}; born 7 February 1931 in [[Mulhouse, France]]) was the founder of the {{Interlanguage link multi|Institute for Genetics and Cellular and Molecular Biology|fr|3=Institut de génétique et de biologie moléculaire et cellulaire}} in [[Strasbourg]], [[France]].<ref>{{Cite web|url=http://www.usias.fr/en/chairs/pierre-chambon/|title=Pierre Chambon - USIAS - University of Strasbourg|website=www.usias.fr|language=fr-FR|access-date=2018-04-30}}</ref> He was one of the leading molecular biologists who utilized gene cloning and sequencing technology to first decipher the structure of eukaryotic genes and their modes of regulation. His major contributions to science include the identification of RNA polymerase II (B){{refn|group=nb|Chambon named his three polymerases A, B, C. The now-more-common designations I, II, III were the nomenclature used by [[Robert G. Roeder]] and [[William J. Rutter]].}}, the identification of transcriptional control elements, the cloning and dissection of [[nuclear hormone receptor]]s, revealing their structure and showing how they contribute to human [[physiology]]. His group was also one of the first to demonstrate, biochemically and electron-microscopically, that the nucleosome is the smallest unit of chromatin (Cell, Vol. 4, 281–300, 1975). He accomplished much of his work in the 1970s – 1990s.


Chambon was elected a Foreign Associate of the US [[National Academy of Sciences]] and to the French [[Académie des Sciences]] in 1985, a foreign member of the [[Royal Swedish Academy of Sciences]] in 1987.<ref>[https://web.archive.org/web/20171110005416/http://www.kva.se/en/Members/Ledamoter-page/?personId=629 Royal Swedish Academy of Sciences: Pierre Chambon]</ref> He was awarded the [[Louisa Gross Horwitz Prize]] from [[Columbia University]] in 1999. In 2003 he was awarded the [[March of Dimes Prize in Developmental Biology]]. He received the [[Albert Lasker Award for Basic Medical Research]] in 2004 for his work in the field. In 2010, Chambon was awarded the [[Gairdner Foundation International Award]] "for the elucidation of fundamental mechanisms of transcription in animal cells and to the discovery of the nuclear receptor superfamily".<ref>[http://www.gairdner.org/awards/2010canadagairdnerawardrecipients/pierrechambon Pierre Chambon, M.D. - The Gairdner Foundation] {{webarchive |url=https://web.archive.org/web/20100611170836/http://www.gairdner.org/awards/2010canadagairdnerawardrecipients/pierrechambon |date=June 11, 2010 }}</ref> In 2018 he received the [[Louisa Gross Horwitz Prize]] for a second time.<ref>[http://www.cumc.columbia.edu/research/horwitz-prize/ Louisa Gross Horwitz Prize 2018]</ref>
Chambon was elected a Foreign Associate of the US [[National Academy of Sciences]] and to the French [[Académie des Sciences]] in 1985, a foreign member of the [[Royal Swedish Academy of Sciences]] in 1987.<ref>{{Cite web |date=2017-11-10 |title=Kungl. Vetenskapsakademien |url=http://www.kva.se/en/Members/Ledamoter-page/?personId=629 |access-date=2023-08-11 |archive-url=https://web.archive.org/web/20171110005416/http://www.kva.se/en/Members/Ledamoter-page/?personId=629 |archive-date=2017-11-10 }}</ref> He was awarded the [[Louisa Gross Horwitz Prize]] from [[Columbia University]] in 1999 and a second time in 2018. In 2003 he was awarded the [[March of Dimes Prize in Developmental Biology]]. He received the [[Albert Lasker Award for Basic Medical Research]] in 2004 for his work in the field. In 2010, Chambon was awarded the [[Gairdner Foundation International Award]] "for the elucidation of fundamental mechanisms of transcription in animal cells and to the discovery of the nuclear receptor superfamily".<ref>[http://www.gairdner.org/awards/2010canadagairdnerawardrecipients/pierrechambon Pierre Chambon, M.D. - The Gairdner Foundation] {{webarchive |url=https://web.archive.org/web/20100611170836/http://www.gairdner.org/awards/2010canadagairdnerawardrecipients/pierrechambon |date=June 11, 2010 }}</ref> In 2018 he received the [[Louisa Gross Horwitz Prize]] for a second time.<ref>{{Cite web |date=2022-11-11 |title=The Louisa Gross Horwitz Prize |url=https://www.cuimc.columbia.edu/research/louisa-gross-horwitz-prize |access-date=2023-08-11 |website=Columbia University Irving Medical Center |language=en}}</ref>
==Notes==
{{reflist|group=nb}}


==References==
==References==
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{{DEFAULTSORT:Chambon, Pierre}}
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[[Category:Members of the United States National Academy of Sciences]]
[[Category:Academic staff of the Collège de France]]
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[[Category:Foreign associates of the National Academy of Sciences]]
[[Category:Members of the French Academy of Sciences]]
[[Category:Members of the French Academy of Sciences]]
[[Category:Members of the Royal Swedish Academy of Sciences]]
[[Category:Members of the Royal Swedish Academy of Sciences]]
[[Category:French molecular biologists]]
[[Category:French molecular biologists]]
[[Category:French geneticists]]
[[Category:French geneticists]]
[[Category:Endocrinologists]]
[[Category:French endocrinologists]]
[[Category:People from Mulhouse]]
[[Category:French people of Jewish descent]]
[[Category:Living people]]
[[Category:Scientists from Mulhouse]]
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[[Category:1931 births]]
[[Category:University of Strasbourg alumni]]
[[Category:University of Strasbourg alumni]]
[[Category:Recipients of the Albert Lasker Award for Basic Medical Research]]
[[Category:Recipients of the Albert Lasker Award for Basic Medical Research]]
[[Category:Fellows of the AACR Academy]]
[[Category:Fellows of the AACR Academy]]
[[Category:Commandeurs of the Légion d'honneur]]
[[Category:Commanders of the Legion of Honour]]
[[Category:Grand Officers of the National Order of Merit (France)]]
[[Category:Grand Officers of the Ordre national du Mérite]]
[[Category:Richard-Lounsbery Award laureates]]




Latest revision as of 10:09, 21 August 2024

Pierre Chambon
Born (1931-02-07) 7 February 1931 (age 93)
Mulhouse, France
NationalityFrench
Known fornuclear hormone receptors
AwardsRichard Lounsbery Award (1982)
Harvey Prize (1987)
Sir Hans Krebs Medal (1990)
Louis-Jeantet Prize for Medicine (1991)[1]
Welch Award in Chemistry (1998)
Louisa Gross Horwitz Prize (1999)
Albert Lasker Award for Basic Medical Research (2004)
Alfred P. Sloan, Jr. Prize (2003)
Gairdner Foundation International Award (2010)
Louisa Gross Horwitz Prize (2018)
Scientific career
InstitutionsInstitute for Genetics and Cellular and Molecular Biology [fr]

Pierre Chambon (French pronunciation: [pjɛʁ ʃɑ̃bɔ̃]; born 7 February 1931 in Mulhouse, France) was the founder of the Institute for Genetics and Cellular and Molecular Biology [fr] in Strasbourg, France.[2] He was one of the leading molecular biologists who utilized gene cloning and sequencing technology to first decipher the structure of eukaryotic genes and their modes of regulation. His major contributions to science include the identification of RNA polymerase II (B)[nb 1], the identification of transcriptional control elements, the cloning and dissection of nuclear hormone receptors, revealing their structure and showing how they contribute to human physiology. His group was also one of the first to demonstrate, biochemically and electron-microscopically, that the nucleosome is the smallest unit of chromatin (Cell, Vol. 4, 281–300, 1975). He accomplished much of his work in the 1970s – 1990s.

Chambon was elected a Foreign Associate of the US National Academy of Sciences and to the French Académie des Sciences in 1985, a foreign member of the Royal Swedish Academy of Sciences in 1987.[3] He was awarded the Louisa Gross Horwitz Prize from Columbia University in 1999 and a second time in 2018. In 2003 he was awarded the March of Dimes Prize in Developmental Biology. He received the Albert Lasker Award for Basic Medical Research in 2004 for his work in the field. In 2010, Chambon was awarded the Gairdner Foundation International Award "for the elucidation of fundamental mechanisms of transcription in animal cells and to the discovery of the nuclear receptor superfamily".[4] In 2018 he received the Louisa Gross Horwitz Prize for a second time.[5]

Notes

[edit]
  1. ^ Chambon named his three polymerases A, B, C. The now-more-common designations I, II, III were the nomenclature used by Robert G. Roeder and William J. Rutter.

References

[edit]
  1. ^ "Professor Pierre CHAMBON | Jeantet". 2017-10-01. Retrieved 2023-08-11.
  2. ^ "Pierre Chambon - USIAS - University of Strasbourg". www.usias.fr (in French). Retrieved 2018-04-30.
  3. ^ "Kungl. Vetenskapsakademien". 2017-11-10. Archived from the original on 2017-11-10. Retrieved 2023-08-11.
  4. ^ Pierre Chambon, M.D. - The Gairdner Foundation Archived June 11, 2010, at the Wayback Machine
  5. ^ "The Louisa Gross Horwitz Prize". Columbia University Irving Medical Center. 2022-11-11. Retrieved 2023-08-11.
[edit]


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