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{{short description|Absence of urine}}
{{Infobox symptom |
{{Infobox medical condition (new)
Name = Anuria |
Image = |
| name = Anuria
Caption = |
| image =
DiseasesDB = 23641 |
| caption =
ICD10 = {{ICD10|R|33||r|30}} |
| pronounce =
ICD9 = {{ICD9|788.5}} |
| field = [[Nephrology]]
ICDO = |
| synonyms = Anuresis
OMIM = |
| symptoms =
MedlinePlus = |
| complications =
| onset =
eMedicineSubj = |
| duration =
eMedicineTopic = |
MeshID = D001002 |
| types =
| causes =
| risks =
| diagnosis =
| differential =
| prevention =
| treatment =
| medication =
| prognosis =
| frequency =
| deaths =
}}
}}


'''Anuria''' means nonpassage of [[urine]],<ref>{{DorlandsDict|one/000006492|anuria}}</ref> in practice is defined as passage of less than 100 [[milliliter]]s of urine in a day.<ref name="urlSUNY Stony Brook Pathology Department HBP310 Inflammation">{{cite web |url=http://www.path.sunysb.edu/coursemat/hbp310urinarymg.htm |title=SUNY Stony Brook Pathology Department HBP310 Inflammation |work= |accessdate=2009-06-15}}</ref> Anuria is often caused by failure in the function of [[kidney]]s. It may also occur because of some severe obstruction like [[kidney stone]]s or [[tumour]]s. It may occur with [[Chronic kidney disease#Stage 5 CKD|end stage renal disease]]. It is a more extreme reduction than [[oliguria]], sometimes called anuresis.
'''Anuria''' is nonpassage of [[urine]],<ref>{{DorlandsDict|one/000006492|anuria}}</ref> in practice is defined as passage of less than 100<ref>Harrison's Principles of Internal Medicine, 19E PAGE 292</ref> [[milliliter]]s of urine in a day.<ref name="urlSUNY Stony Brook Pathology Department HBP310 Inflammation">{{cite web|url=http://www.path.sunysb.edu/coursemat/hbp310urinarymg.htm |title=SUNY Stony Brook Pathology Department HBP310 Inflammation |access-date=2009-06-15 |url-status=dead |archive-url=https://web.archive.org/web/20090427153521/http://www.path.sunysb.edu/coursemat/hbp310urinarymg.htm |archive-date=2009-04-27 }}</ref> Anuria is often caused by [[Kidney failure|failure]] in the function of [[kidney]]s. It may also occur because of some severe obstruction like [[kidney stone]]s or [[tumour]]s. It may occur with [[Chronic kidney disease#Stage 5 CKD|end stage kidney disease]]. It is a more extreme reduction than [[oliguria]] (hypouresis), with 100 mL/day being the conventional (albeit slightly arbitrary) cutoff point between the two.

==Signs and symptoms==
Anuria itself is a symptom, not a disease. It is often associated with other symptoms of [[kidney failure]], such as lack of appetite, weakness, [[nausea]] and [[vomiting]]. These are mostly the result of buildup of [[Toxin|toxins]] in the blood which would normally be removed by healthy kidneys.


==Causes==
==Causes==
Failure of kidney function, which can have multiple causes including medications or toxins (e.g., antifreeze); [[diabetes]]; high blood pressure. Stones or tumours in the urinary tract can also cause it by creating an obstruction to urinary flow. High blood calcium, oxalate, or uric acid, can contribute to the risk of stone formation. In males, an enlarged [[prostate gland]] is a common cause of obstructive anuria.
Failure of kidney function, which can have multiple causes including medications or toxins (e.g., antifreeze, [[cephalosporin]]s, ACEIs); [[diabetes]]; high blood pressure. Stones or tumours in the urinary tract can also cause it by creating an obstruction to urinary flow. High blood calcium, oxalate, or uric acid, can contribute to the risk of stone formation. In males, an enlarged [[prostate gland]] is a common cause of obstructive anuria.


Acute anuria, where the decline in urine production occurs quickly, is usually a sign of obstruction or [[acute renal failure]]. Acute renal failure can be caused by factors not related to the kidney, such as [[heart failure]], [[mercury poisoning]], infection, and other conditions that cause the kidney to be deprived of blood flow.
Acute anuria, where the decline in urine production occurs quickly, is usually a sign of obstruction or [[acute kidney failure]]. Acute kidney failure can be caused by factors not related to the kidney, such as [[heart failure]], [[mercury poisoning]], infection, and other conditions that cause the kidney to be deprived of blood flow.

==Symptoms==
Anuria itself is a symptom, not a disease. It is often associated with other symptoms of kidney failure, such as lack of appetite, weakness, nausea and vomiting. These are mostly the result of buildup of toxins in the blood which would normally be removed by healthy kidneys.


==Treatment==
==Treatment==
Treatment is dependent on the underlying cause of this symptom. The most easily treatable cause is obstruction of urine flow, which is often solved by insertion of a [[urinary catheterization|urinary catheter]] into the [[urinary bladder]].
Treatment is dependent on the underlying cause of this symptom. The most easily treatable cause is obstruction of urine flow, which is often solved by insertion of a [[urinary catheterization|urinary catheter]] into the [[urinary bladder]].


[[Mannitol]] is a medicine that is used to increase the amount of water removed from the blood and thus improve the blood flow to the kidneys. However, mannitol is contraindicated in anuria secondary to renal disease, severe dehydration, intracranial bleeding (except during [[craniotomy]]), severe pulmonary congestion, or pulmonary edema.
[[Mannitol]] is a medicine that is used to increase the amount of water removed from the blood and thus improve the blood flow to the kidneys. However, mannitol is contraindicated in anuria secondary to renal disease, severe dehydration, intracranial bleeding (except during [[craniotomy]]), severe pulmonary congestion, or [[pulmonary edema]].


[[Dextrose]] and [[Dobutamine]] are both used to increase blood flow to the kidney and act within 30 to 60 minutes.
[[Dextrose]] and [[dobutamine]] are both used to increase blood flow to the kidney and act within 30 to 60 minutes.


==References==
==References==
{{reflist}}
{{Reflist}}


== External links ==
{{Medical resources
| DiseasesDB = 23641
| ICD10 = {{ICD10|R|34||r|30}}
| ICD9 = {{ICD9|788.5}}
| ICDO =
| OMIM =
| MedlinePlus =
| eMedicineSubj =
| eMedicineTopic =
| MeshID = D001002
}}
{{Urinary system symptoms and signs}}
{{Urinary system symptoms and signs}}
{{Authority control}}


[[Category:Symptoms and signs: Urinary system]]
[[Category:Symptoms and signs: Urinary system]]

Latest revision as of 21:14, 26 August 2024

Anuria
Other namesAnuresis
SpecialtyNephrology

Anuria is nonpassage of urine,[1] in practice is defined as passage of less than 100[2] milliliters of urine in a day.[3] Anuria is often caused by failure in the function of kidneys. It may also occur because of some severe obstruction like kidney stones or tumours. It may occur with end stage kidney disease. It is a more extreme reduction than oliguria (hypouresis), with 100 mL/day being the conventional (albeit slightly arbitrary) cutoff point between the two.

Signs and symptoms

[edit]

Anuria itself is a symptom, not a disease. It is often associated with other symptoms of kidney failure, such as lack of appetite, weakness, nausea and vomiting. These are mostly the result of buildup of toxins in the blood which would normally be removed by healthy kidneys.

Causes

[edit]

Failure of kidney function, which can have multiple causes including medications or toxins (e.g., antifreeze, cephalosporins, ACEIs); diabetes; high blood pressure. Stones or tumours in the urinary tract can also cause it by creating an obstruction to urinary flow. High blood calcium, oxalate, or uric acid, can contribute to the risk of stone formation. In males, an enlarged prostate gland is a common cause of obstructive anuria.

Acute anuria, where the decline in urine production occurs quickly, is usually a sign of obstruction or acute kidney failure. Acute kidney failure can be caused by factors not related to the kidney, such as heart failure, mercury poisoning, infection, and other conditions that cause the kidney to be deprived of blood flow.

Treatment

[edit]

Treatment is dependent on the underlying cause of this symptom. The most easily treatable cause is obstruction of urine flow, which is often solved by insertion of a urinary catheter into the urinary bladder.

Mannitol is a medicine that is used to increase the amount of water removed from the blood and thus improve the blood flow to the kidneys. However, mannitol is contraindicated in anuria secondary to renal disease, severe dehydration, intracranial bleeding (except during craniotomy), severe pulmonary congestion, or pulmonary edema.

Dextrose and dobutamine are both used to increase blood flow to the kidney and act within 30 to 60 minutes.

References

[edit]
  1. ^ "anuria" at Dorland's Medical Dictionary
  2. ^ Harrison's Principles of Internal Medicine, 19E PAGE 292
  3. ^ "SUNY Stony Brook Pathology Department HBP310 Inflammation". Archived from the original on 2009-04-27. Retrieved 2009-06-15.
[edit]