Hypertrophy: Difference between revisions
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{{short description|Increase in the volume of an organ or tissue due to the enlargement of its component cells}} |
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{{Infobox medical condition (new) |
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| name = Hypertrophy |
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| caption = Hypertrophy results from an increase in cell size, whereas [[hyperplasia]] stems from an increase in cell number.| |
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[[Image:Ipertrofia miocardica.jpg|thumb|left|200px|Forensic post-mortem examination of a case of [[hypertrophic cardiomyopathy]], showing thickening of the [[cardiac muscle]].]] |
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'''Hypertrophy''' |
'''Hypertrophy''' is the increase in the volume of an organ or tissue due to the enlargement of its component [[Cell (biology)|cells]].<ref name="Muscle Hypertrophy">{{cite web|last1=Hernandez|first1=Richard|last2=Kravitz|first2=Len|title=Skeletal muscle hypertrophy|url=https://www.unm.edu/~lkravitz/Article%20folder/hypertrophy.html|website=www.unm.edu}}</ref> It is distinguished from [[hyperplasia]], in which the cells remain approximately the same size but increase in number.<ref>{{Cite web|title=Hyperplasia: MedlinePlus Medical Encyclopedia|url=https://medlineplus.gov/ency/article/003441.htm|access-date=2023-02-19|website=medlineplus.gov|language=en}}</ref> Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the [[hormone|hormonally]] induced proliferation and enlargement of the cells of the [[uterus]] during [[pregnancy]]. |
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'''Eccentric hypertrophy''' is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the [[left ventricle]] of heart.<ref name=Kusumoto2004 >{{citation | last=Kusumoto | first=F. M. | year=2004 | title=Cardiovascular Pathophysiology | publisher=Hayes Barton Press | isbn=978-1-59377-189-8 | url=https://books.google.com/books?id=FHT_w_gUeK4C& |
'''Eccentric hypertrophy''' is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the [[left ventricle]] of heart.<ref name=Kusumoto2004 >{{citation | last=Kusumoto | first=F. M. | year=2004 | title=Cardiovascular Pathophysiology | publisher=Hayes Barton Press | isbn=978-1-59377-189-8 | url=https://books.google.com/books?id=FHT_w_gUeK4C&q=Eccentric+hypertrophy&pg=PA22 | pages=20–22 }}{{Dead link|date=August 2024 |bot=InternetArchiveBot |fix-attempted=yes }}</ref> [[Sarcomere]]s are added in series, as for example in [[dilated cardiomyopathy]] (in contrast to [[hypertrophic cardiomyopathy]], a type of [[concentric hypertrophy]], where sarcomeres are added in parallel). |
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==Gallery== |
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<gallery> |
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Gould Pyle 234.jpg|[[Breast hypertrophy|Breasts]] |
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Hypertrophied clitoris.jpg|[[Clitoromegaly|Clitoris]] |
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Head of a boy with hypertrophy of the ear Wellcome L0062496.jpg|[[Ear]] |
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Gould Pyle 127.jpg|[[Fingers]] |
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Feet from a case of partial hypertrophy of the foot Wellcome L0061374.jpg|[[Foot]] (partial) |
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Hypertrophy of the gums Wellcome L0062728.jpg|[[Gingival enlargement|Gums]] |
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Hypertrophy from Carswell, 1838. Wellcome L0000931.jpg|[[Hypertrophic cardiomyopathy|Heart]] |
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Kidney hypertrophy Wellcome L0005308.jpg|[[Kidneys]] |
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Face of man with hypertrophy of the temporal muscles Wellcome L0062508.jpg|[[Temporal muscles]] |
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Tibia affected by chronic inflammatory hypertrophy Wellcome L0061256.jpg|[[Tibia]] (inflammatory) |
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Inflammatory hypertrophy of the tongue Wellcome L0061277.jpg|[[Macroglossia|Tongue]] (inflammatory) |
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Gould Pyle 100.jpg|[[Upper lip]] |
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Operative gynecology - (1906) (14780430391).jpg|[[Urethral meatus]] |
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</gallery> |
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==See also== |
==See also== |
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== External links == |
== External links == |
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{{Medical resources |
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| MeshID = D006984 |
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| SNOMED CT = 56246009 |
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{{Pathology}} |
{{Pathology}} |
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{{Authority control}} |
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[[Category:Muscular system]] |
[[Category:Muscular system]] |
Latest revision as of 16:15, 27 August 2024
This article needs more reliable medical references for verification or relies too heavily on primary sources. (May 2017) |
Hypertrophy | |
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Hypertrophy results from an increase in cell size, whereas hyperplasia stems from an increase in cell number. |
Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its component cells.[1] It is distinguished from hyperplasia, in which the cells remain approximately the same size but increase in number.[2] Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the hormonally induced proliferation and enlargement of the cells of the uterus during pregnancy.
Eccentric hypertrophy is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the left ventricle of heart.[3] Sarcomeres are added in series, as for example in dilated cardiomyopathy (in contrast to hypertrophic cardiomyopathy, a type of concentric hypertrophy, where sarcomeres are added in parallel).
Gallery
[edit]-plasia and -trophy |
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See also
[edit]- Athlete's heart
- Ventricular hypertrophy (including left ventricular hypertrophy and right ventricular hypertrophy)
- Muscle hypertrophy
- List of biological development disorders
References
[edit]- ^ Hernandez, Richard; Kravitz, Len. "Skeletal muscle hypertrophy". www.unm.edu.
- ^ "Hyperplasia: MedlinePlus Medical Encyclopedia". medlineplus.gov. Retrieved 2023-02-19.
- ^ Kusumoto, F. M. (2004), Cardiovascular Pathophysiology, Hayes Barton Press, pp. 20–22, ISBN 978-1-59377-189-8[permanent dead link ]