Talk:Melatonin: Difference between revisions

Content deleted Content added

Inline

Latest revision as of 07:34, 29 September 2024

This is the talk page for discussing improvements to the Melatonin article.
This is not a forum for general discussion of the article's subject.

Put new text under old text. Click here to start a new topic.
New to Wikipedia? Welcome! Learn to edit; get help.

Article policies

Find sources: Google (books · news · scholar · free images · WP refs) · FENS · JSTOR · TWL

Archives: Index, 1, 2, 3: 3 months

Pharmacology High‑importance

	This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PharmacologyWikipedia:WikiProject PharmacologyTemplate:WikiProject Pharmacologypharmacology
High	This article has been rated as High-importance on the project's importance scale.

Chemicals: Core Mid‑importance

	This article is within the scope of WikiProject Chemicals, a daughter project of WikiProject Chemistry, which aims to improve Wikipedia's coverage of chemicals. To participate, help improve this article or visit the project page for details on the project.ChemicalsWikipedia:WikiProject ChemicalsTemplate:WikiProject Chemicalschemicals
Mid	This article has been rated as Mid-importance on the project's importance scale.
	This is a core article in the WikiProject Chemicals worklist.

Molecular Biology: MCB

	This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology
???	This article has not yet received a rating on the importance scale.
	This article is supported by the Molecular and Cell Biology task force (assessed as High-importance).

Neuroscience Mid‑importance

	This article is within the scope of WikiProject Neuroscience, a collaborative effort to improve the coverage of Neuroscience on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.NeuroscienceWikipedia:WikiProject NeuroscienceTemplate:WikiProject Neuroscienceneuroscience
Mid	This article has been rated as Mid-importance on the project's importance scale.

Physiology Mid‑importance

	This article is within the scope of WikiProject Physiology, a collaborative effort to improve the coverage of Physiology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PhysiologyWikipedia:WikiProject PhysiologyTemplate:WikiProject PhysiologyPhysiology
Mid	This article has been rated as Mid-importance on the importance scale.
	This article has not yet been associated with a particular area.

Autism Low‑importance

	This article is within the scope of WikiProject Autism, a collaborative effort to improve the coverage of all aspects of autism and autistic culture on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.AutismWikipedia:WikiProject AutismTemplate:WikiProject AutismAutism
Low	This article has been rated as Low-importance on the project's importance scale.

Epilepsy Low‑importance

	This article is within the scope of WikiProject Epilepsy, a collaborative effort to improve the coverage of epilepsy and epileptic seizures on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.EpilepsyWikipedia:WikiProject EpilepsyTemplate:WikiProject EpilepsyEpilepsy
Low	This article has been rated as Low-importance on the project's importance scale.

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Melatonin.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Melatonin and the liver

"Its use is not recommended during pregnancy or breastfeeding or for those with liver disease.[7][13]"

New studies suggest that melatonin supplementation may be a promising adjunct for liver disease.

https://www.mdpi.com/2072-6643/10/9/1135 — Preceding unsigned comment added by Dreizweins (talk • contribs) 23:57, 8 September 2020 (UTC)[reply]

Orcid IDs

@Invasive Spices: Why are you adding Orcid IDs to citations? It polutes the meta data. You are also hyping the authors. Focus on the conclusions of the study, not who wrote it. Thanks. Boghog (talk) 19:06, 24 September 2021 (UTC)[reply]

That's pretty funny coming from someone who removes and damages as much author data as you can. As for hyping the authors, I normally don't and would agree that is inappropriate, however I do so if working from a rev and the rev thinks that paper is so singular as to be worth promoting. (Also I don't see any such on this article. But I've done that elsewhere.) Invasive Spices (talk) 19:20, 24 September 2021 (UTC)[reply]
- Again, I am trying to have a serious discussion, and you refuse to directly respond. Why does every single author deserve an external link to their other publications? Boghog (talk) 19:26, 24 September 2021 (UTC)[reply]

Abbriviations

In image of head, what go SCN, RHT, MCRGC denote? Use hormonal, not humoral, reminiscent of Ancient Greek 5 humors. 98.144.238.191 (talk) 14:17, 12 June 2022 (UTC)[reply]

To add to article

Basic information to add to this article: the etymology of the word "melatonin." According to Wiktionary, it is a blend of melanin +‎ serotonin. If that's true, why not add this information to this article, in order to help make it properly encyclopedic? 173.88.246.138 (talk) 01:11, 9 March 2023 (UTC)[reply]

Useful suggestion, and done. Chhandama (talk) 09:09, 10 March 2023 (UTC)[reply]

On skin lightening in frogs

The head says that the hormone elicits skin lightening in the common frog, with a wikilink to skin whitening, where it is described as "the practice of using chemical substances in an attempt to lighten the skin or provide an even skin color by reducing the melanin concentration in the skin." That specific human practice doesn't seem to be a relevant link unless I'm missing something. Understandable mistake, but remove? Moonjail (talk) 04:13, 8 April 2023 (UTC)[reply]

I was reading this too and thinking was this someone's idea of having a wind-up? (joke). How do they make the jump from the 'brain of cows' to 'lightening skins of frogs'? Was it a lab experiment? Did a cow trip and fall on a frog and the brain splat out and made the frog lighter. So many questions with that statement that seem questionable and more like April 1. (???) CaribDigita (talk) 03:27, 14 June 2024 (UTC)[reply]

Source of melatonin not stated

this article does not state the source of melatonin used in either Rx or OTC products. If it has a synthetic source that should be under scrutiny because in the past impurities from synthetic tryptophan had caused abnormal blood cell production. Both melatonin and tryptophan have in common an indole ring . 2603:6011:F7F0:1C30:3957:B73:DB53:46D9 (talk) 03:25, 13 October 2023 (UTC)[reply]

@@ Line 1: / Line 1: @@
 {{Talk header}}
+{{WikiProject banner shell|class=B|vital=yes|1=
-{{WikiProjectBannerShell|1=
-{{WikiProject Pharmacology|class=B|importance=high}}
+{{WikiProject Pharmacology|importance=high}}
-{{WikiProject Chemicals|core|class=B|importance=Mid}}
+{{WikiProject Chemicals|core|importance=Mid}}
-{{WikiProject Molecular and Cellular Biology|class=B|importance=High}}
+{{WikiProject Molecular Biology|MCB=yes|MCB-importance=High}}
-{{WikiProject Medicine|class=B|importance=Mid}}
+{{WikiProject Neuroscience|importance=mid}}
-{{WPNEURO|class=B|importance=mid}}
+{{WikiProject Physiology|importance=mid|field=}}
-{{WikiProject Dietary Supplements | class=B | importance=high }}
+{{WikiProject Autism|importance=Low}}
-{{WikiProject Physiology|class=B|importance=mid|field=}}
+{{WikiProject Epilepsy|importance=Low}}
-{{WikiProject Autism|class=B|importance=Low}}
-{{WikiProject Epilepsy|class=B|importance=Low}}
 }}
 {{Reliable sources for medical articles}}
@@ Line 23: / Line 21: @@
 }}
+== Melatonin and the liver ==
-{{RxCOTWprev}}
-{{Archive box|
-[[/Archive 1]]<br />
-[[/Archive 2]]<br />
-[[/Archive 3]]}}
+"Its use is not recommended during pregnancy or breastfeeding or for those with liver disease.[7][13]"
-== Reference 56 is invalid ==
+New studies suggest that melatonin supplementation may be a promising adjunct for liver disease.
-http://www.nlm.nih.gov/medlineplus/druginfo/natural/940.html#DrugInteractions - link returns 404. <<==  unsigned edit by IP  63.87.61.109
+https://www.mdpi.com/2072-6643/10/9/1135  <!-- Template:Unsigned --><small class="autosigned">—&nbsp;Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[User:Dreizweins|Dreizweins]] ([[User talk:Dreizweins#top|talk]] • [[Special:Contributions/Dreizweins|contribs]]) 23:57, 8 September 2020 (UTC)</small> <!--Autosigned by SineBot-->
-::I've replaced the deadlink with a ref from Univ. of Maryland.  --[[User:Hordaland|Hordaland]] ([[User talk:Hordaland|talk]]) 02:29, 27 January 2016 (UTC)
+== Orcid IDs ==
-== Availability in Eastern Europe ==
-Although I cannot quote any reliable sources, Melatonin tablets are freely sold across most of Eastern Europe. There is also an sublingual composition marketed as Somni-X. It is a fast onset spray, applied under the tongue.  --[[User:Lasombra bg|lasombra bg]] ([[User talk:Lasombra bg|talk]]) 21:45, 16 September 2016 (UTC)
+{{ping|Invasive Spices}} Why are you adding [https://en.wikipedia.org/enwiki/w/index.php?title=Melatonin&type=revision&diff=1046080980&oldid=1046039043 Orcid IDs] to citations?  It polutes the meta data. You are also hyping the authors. Focus on the conclusions of the study, not who wrote it. Thanks. [[User:Boghog|Boghog]] ([[User talk:Boghog|talk]]) 19:06, 24 September 2021 (UTC)
+* That's pretty funny coming from someone who removes and damages as much author data as you can. As for hyping the authors, I normally don't and would agree that is inappropriate, however I do so if working from a rev and the rev thinks that paper is so singular as to be worth promoting. (Also I don't see any such on this article. But I've done that elsewhere.) [[User:Invasive Spices|Invasive Spices]] ([[User talk:Invasive Spices|talk]]) 19:20, 24 September 2021 (UTC)
+** Again, I am trying to have a serious discussion, and you refuse to directly respond.  Why does every single author deserve an external link to their other publications?  [[User:Boghog|Boghog]] ([[User talk:Boghog|talk]]) 19:26, 24 September 2021 (UTC)
+== Abbriviations ==
-== Melatonin should be described as a neurotransmitter ==
+In image of head, what go SCN, RHT, MCRGC denote? Use hormonal, not humoral, reminiscent of Ancient Greek 5 humors. [[Special:Contributions/98.144.238.191|98.144.238.191]] ([[User talk:98.144.238.191|talk]]) 14:17, 12 June 2022 (UTC)
-That Melatonin acts as a neurotransmitter is implicit on this page in that it's part of the "neurotransmitters" series, and also that the *effects* of Melatonin receptors being engaged is described in the "Functions" section, however it is never clearly stated. See: Serotonin page functions section.
---[[User:Whilom|Whilom Chime]] ([[User talk:Whilom|talk]]) 17:09, 4 December 2016 (UTC)
+== To add to article ==
-: It is actually a [[hormone]], not a [[neurotransmitter]] that has effects on more distant cells, not just adjacent cells connected by synapses.  I have edited the lead so that it now stated that it is a hormone in the lead sentence. [[User:Boghog|Boghog]] ([[User talk:Boghog|talk]]) 18:54, 4 December 2016 (UTC)
+Basic information to add to this article: the etymology of the word "melatonin." According to Wiktionary, it is a blend of [[melanin]] +‎ [[serotonin]]. If that's true, why not add this information to this article, in order to help make it properly encyclopedic? [[Special:Contributions/173.88.246.138|173.88.246.138]] ([[User talk:173.88.246.138|talk]]) 01:11, 9 March 2023 (UTC)
-:: Apologies, I certainly didn't mean to imply that it isn't a hormone, but that like [[norepinephrine]] it is both.  I'm definitely not an expert, but I'm assuming its activity with Melatonin receptors in the suprachiasmatic nuclei of the hypothalamus means that it is also a neurotransmitter.  I'm quite willing to be educated that it is not, but if that's the case it should be removed from the [[neurotransmitter]] page and the neurotransmitter list.--[[User:Whilom|Whilom Chime]] ([[User talk:Whilom|talk]]) 20:14, 4 December 2016 (UTC)
+:Useful suggestion, and done. [[User:Chhandama|Chhandama]] ([[User talk:Chhandama|talk]]) 09:09, 10 March 2023 (UTC)
-::: No problem.  I am not an expert either. The sources that I have read invariably describe melatonin as a (neuro)hormone that is synthesized in the pineal gland.  For melatonin to be classified as a neurotransmitter, it would also need to be released from presynaptic neurons and I can find no support for that in the literature. Hence as you suggest, I think melatonin should be removed from the {{tl|Neurotransmitters}} navbox and [[neurotransmitter]] article. [[User:Boghog|Boghog]] ([[User talk:Boghog|talk]]) 06:12, 5 December 2016 (UTC)
+== On skin lightening in frogs ==
-== Review article saying that melatonin is effective for treating primary insomnia ==
+The head says that the hormone elicits skin lightening in the common frog, with a wikilink to [[skin whitening]], where it is described as "the practice of using chemical substances in an attempt to lighten the skin or provide an even skin color by reducing the melanin concentration in the skin." That specific human practice doesn't seem to be a relevant link unless I'm missing something. Understandable mistake, but remove? [[User:Moonjail|Moonjail]] ([[User talk:Moonjail|talk]]) 04:13, 8 April 2023 (UTC)
-Here's the article: https://www.ncbi.nlm.nih.gov/pubmed/28648359
-I don't want to edit the part of the article which says that there's not enough evidence for this myself owing to my very limited knowledge of such subjects, but perhaps that should be done if that review article is right. [[User:Dakane2|Dakane2]] ([[User talk:Dakane2|talk]]) 19:37, 23 January 2018 (UTC)
+:I was reading this too and thinking was this someone's idea of having a wind-up? (joke). How do they make the jump from the 'brain of cows' to 'lightening skins of frogs'? Was it a lab experiment? Did a cow trip and fall on a frog and the brain splat out and made the frog lighter.  So many questions with that statement that seem questionable and more like April 1. (???) [[User:CaribDigita|CaribDigita]] ([[User talk:CaribDigita|talk]]) 03:27, 14 June 2024 (UTC)
-== medical uses and side effects categories overlap ==
+== Source of melatonin not stated ==
-There are quite a few side effects listed under medical uses. Perhaps these categories should simoly be combined into "Medical uses and side effects". <span style="background:#F0F0FF; padding:3px 9px 4px">'''[[User:Dig deeper|<font color="Green">Dig</font>&nbsp;<sub><big><font color="Brown">deeper</font></big></sub>]]''' </span> <sup>[[User talk:Dig deeper|'''talk''']]</sup> 04:11, 1 March 2018 (UTC)
+this article does not state the source of melatonin used in either Rx or OTC products. If it has a synthetic source that should be under scrutiny because in the past impurities from synthetic tryptophan had caused abnormal blood cell production. Both melatonin and tryptophan have in common an indole ring  . [[Special:Contributions/2603:6011:F7F0:1C30:3957:B73:DB53:46D9|2603:6011:F7F0:1C30:3957:B73:DB53:46D9]] ([[User talk:2603:6011:F7F0:1C30:3957:B73:DB53:46D9|talk]]) 03:25, 13 October 2023 (UTC)