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{{short description|Australian academic}}
{{cleanup-reorganize|date=August 2014}}
{{Use dmy dates|date=April 2022}}
[[File:Jane Visvader.jpg|thumb|Jane Visvader]]


{{Infobox scientist
Professor '''Jane Visvader''' is a [[scientist]] specialising in [[breast cancer]] research who works for the [[Walter and Eliza Hall Institute]] in [[Melbourne]], [[Australia]]. She is the joint head of the Breast Cancer Laboratory with Professor Geoff Lindeman.<ref>{{cite web|url=http://www.wehi.edu.au/faculty_members/professor_jane_visvader |title=Professor Jane Visvader |publisher= |date= |accessdate=2014-08-14}}</ref> In 2008, Jane Visvader was a joint recipient of the GlaxoSmithKline Award for Research Excellence <ref>{{cite web|url=http://www.wehi.edu.au/site/latest_news/drs_lindeman_and_visvader_recognised_for_outstanding_breast_cancer_research |title=Latest News - Walter and Eliza Hall Institute of Medical Research |publisher= |date= |accessdate=2014-08-14}}</ref> for outstanding contribution to Breast Cancer research. Professor Visvader was made a Fellow of the [[Australian Academy of Science]] in 2012.<ref>{{cite web|url=http://www.science.org.au/fellowship-list?name=visvader&field_d_year_of_election_value%5Bmin%5D%5Byear%5D=1954&field_d_year_of_election_value%5Bmax%5D%5Byear%5D=2014 |title=Fellowship list - Australian Academy of Science |publisher=Science.org.au |date= |accessdate=2014-08-14}}</ref> Professor Visvader's most recent award is the 2014 Royal Society of Victoria Research Medal for Scientific Excellence in Biomedical & Health Sciences.<ref>{{cite web|url=http://www.royalsocietyvictoria.org.au/news/ |title=News &#124; Royal Society of Victoria &#124; Promoting Science and Science Education |publisher=Royalsocietyvictoria.org.au |date= |accessdate=2014-08-14}}</ref>
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'''Jane Visvader''' is a [[scientist]] specialising in [[breast cancer]] research who works for the [[Walter and Eliza Hall Institute]] in [[Melbourne]], [[Australia]]. She is the joint head of the Breast Cancer Laboratory with Geoff Lindeman.<ref>{{cite web|url=http://www.wehi.edu.au/faculty_members/professor_jane_visvader |title=Professor Jane Visvader |publisher= |date= |accessdate=2014-08-14}}</ref>


==Education and career==
==Education ==
Visvader holds a PhD in [[Biochemistry]] from the [[University of Adelaide]] having studied structure and function of citrus exocortis viroid<ref>{{cite web|url=http://trove.nla.gov.au/work/3750664?q=+Visvader&c=book&versionId=21400027+49704861 |title=Structure and function of citrus exocortis viroid / by Jane Ellen Visvader. - Version details - Trove |publisher=Trove.nla.gov.au |date= 2006-12-28|accessdate=2014-08-14}}</ref>


==Career and research==
Professor Visvader holds a PhD in [[Biochemistry]] from the [[University of Adelaide]] having studied structure and function of citrus exocortis viroid<ref>{{cite web|url=http://trove.nla.gov.au/work/3750664?q=+Visvader&c=book&versionId=21400027+49704861 |title=Structure and function of citrus exocortis viroid / by Jane Ellen Visvader. - Version details - Trove |publisher=Trove.nla.gov.au |date= |accessdate=2014-08-14}}</ref> and has undertaken postdoctoral studies in the Verma Laboratory ([[Salk Institute]], San Diego) and Adams Laboratory (Walter and Eliza Hall Institute (WEHI)). She has also worked at the Children's Hospital/[[Harvard Medical School]] in [[Boston]] before returning to Victoria in 1997 to establish a Breast Cancer Laboratory at WEHI.<ref>{{cite web|url=http://www.royalsocietyvictoria.org.au/news/ |title=News &#124; Royal Society of Victoria &#124; Promoting Science and Science Education |publisher=Royalsocietyvictoria.org.au |date= |accessdate=2014-08-14}}</ref>
After her PhD <ref>{{cite web | url=https://www.centenary.org.au/people/professor-jane-visvader/ | title=Professor Jane Visvader }}</ref> in the Department of Biochemistry at the University of Adelaide , she was a [[postdoctoral researcher]] with [[Inder Verma]] ([[Salk Institute]], San Diego) and [[Jerry Adams]] (Walter and Eliza Hall Institute (WEHI)).<ref name="auto">{{cite web|url=http://www.royalsocietyvictoria.org.au/news/ |title=News &#124; Royal Society of Victoria &#124; Promoting Science and Science Education |publisher=Royalsocietyvictoria.org.au |date= |accessdate=2014-08-14}}</ref> She worked at the Children's Hospital/[[Harvard Medical School]] in [[Boston]] before returning to Victoria in 1997 to establish a Breast Cancer Laboratory at WEHI.<ref name="auto"/>


Visvader has published work investigating the role of cells of origin in cancer<ref>{{Cite journal | doi=10.1038/nature09781| pmid=21248838| title=Cells of origin in cancer| journal=Nature| volume=469| issue=7330| pages=314–322| year=2011| last1=Visvader| first1=Jane E.| bibcode=2011Natur.469..314V| s2cid=4418009}}</ref> and in particular focuses on the role of stem cells,<ref>{{Cite journal | doi=10.1038/nature12948|pmid = 24463516| title=In situ identification of bipotent stem cells in the mammary gland| journal=Nature| volume=506| issue=7488| pages=322–327| year=2014| last1=Rios| first1=Anne C.| last2=Fu| first2=Nai Yang| last3=Lindeman| first3=Geoffrey J.| last4=Visvader| first4=Jane E.|bibcode = 2014Natur.506..322R|s2cid = 205237171}}</ref><ref>{{Cite journal | doi=10.1016/j.stem.2012.05.007| pmid=22704512| title=Cancer Stem Cells: Current Status and Evolving Complexities| journal=Cell Stem Cell| volume=10| issue=6| pages=717–728| year=2012| last1=Visvader| first1=Jane E.| last2=Lindeman| first2=Geoffrey J.| doi-access=free}}</ref> which she believes may be a key to understanding breast cancer.<ref>{{Cite journal|author= Giovanni Valenti |url=http://www.eurostemcell.org/commentanalysis/interview-jane-visvader-stem-cells-breast |title=Interview with Jane Visvader: stem cells in the breast &#124; Europe's stem cell hub |journal=Nature |volume=439 |issue=7072 |pages=84–88 |doi=10.1038/nature04372 |pmid=16397499 |date=2012-01-11 |s2cid=2662840 |accessdate=2014-08-14}}</ref>
==Research==
Professor Visvader has published work considering the role of Cells of Origin in Cancer <ref>http://www.nature.com/nature/journal/v469/n7330/full/nature09781.html</ref> and in particular focuses on the role of stem cells <ref>http://www.nature.com/nature/journal/v506/n7488/full/nature12948.html</ref><ref>http://www.cell.com/cell-stem-cell/abstract/S1934-5909%2812%2900240-8</ref> which she believes may be a key to understanding breast cancer.<ref>{{cite web|author= Giovanni Valenti |url=http://www.eurostemcell.org/commentanalysis/interview-jane-visvader-stem-cells-breast |title=Interview with Jane Visvader: stem cells in the breast &#124; Europe's stem cell hub |doi=10.1038/nature04372 |publisher=EuroStemCell |date=2012-01-11 |accessdate=2014-08-14}}</ref>


Visvader is a board member of the Cancer Council Victoria, Medical & Scientific Committee.<ref>{{Cite web|url=https://www.cancervic.org.au/about/governance/executive-committee|title=Board of Directors - Cancer Council Victoria}}</ref>
==Patents==
Prof. Visvader is a named inventor on five [[patent]]s relating to cancer research focused on [[stem cell]] isolation and diagnostics.<ref>{{cite web|url=http://patents.justia.com/inventor/jane-visvader |title=Patents by Inventor Jane Visvader - Justia Patents Database |publisher=Patents.justia.com |date= |accessdate=2014-08-14}}</ref>


===Patents===
*Method Of Cell Isolation, Application number: 20080038230
Visvader is a named inventor on five [[patent]]s relating to cancer research focused on [[stem cell]] isolation and diagnostics.<ref>{{cite web|url=http://patents.justia.com/inventor/jane-visvader |title=Patents by Inventor Jane Visvader - Justia Patents Database |publisher=Patents.justia.com |date= |accessdate=2014-08-14}}</ref>
*Differentiation and/or proliferation modulating agents and uses therefor, Application number: 20060166917

*Novel phosphoprotein, Application number: 20060148032
*Method of diagnosis and treatment and agents useful for same, Application number: 20050048528
*Method Of Cell Isolation, Application number: 20080038230
*Differentiation and/or proliferation modulating agents and uses therefor, Application number: 20060166917
*Novel phosphoprotein, Application number: 20060148032
*Method of diagnosis and treatment and agents useful for same, Application number: 20050048528
*Differentiation and/or proliferation modulating agents and uses therefor, Application number: 20030175971
*Differentiation and/or proliferation modulating agents and uses therefor, Application number: 20030175971

==Awards and recognition==
*2008 GlaxoSmithKline Award for Research Excellence (Joint with Geoff Lindeman)<ref>{{cite web|url=https://au.gsk.com/en-au/research/supporting-research/gsk-award-for-research-excellence/alumni-members-1/ |title=GSK Alumni Members|accessdate=2021-02-09}}</ref>
* 2012 [[list of Fellows of the Australian Academy of Science|Fellow of the Australian Academy of Science]]<ref>{{cite web|url=http://www.science.org.au/fellowship-list?name=visvader&field_d_year_of_election_value%5Bmin%5D%5Byear%5D=1954&field_d_year_of_election_value%5Bmax%5D%5Byear%5D=2014 |title=Fellowship list - Australian Academy of Science |publisher=Science.org.au |date= |accessdate=2014-08-14}}</ref>
*2014 Royal Society of Victoria Research Medal for Scientific Excellence in Biomedical & Health Sciences.<ref name="auto"/>
*2016 [[National Health and Medical Research Council]] Elizabeth Blackburn Fellowship <ref>{{cite web|url=https://medicine.unimelb.edu.au/archive-news/top-nhmrc-research-recognised |title=Top NHMRC research recognised|accessdate=2021-02-09}}</ref>
*2016 [[Lemberg Medal]], Australian Society for Biochemistry and Molecular Biology <ref>{{cite web|url=https://www.asbmb.org.au/awards/jane_visvader-html/|title=THE 2016 LEMBERG MEDAL: JANE VISVADER |accessdate=9 February 2021}}</ref>
*2016 Fellowship of the Australian Academy of Health and Medical Sciences <ref name="aahms oct 2016">{{cite web|url=http://www.aahms.org/wp-content/uploads/2016/10/AAHMS-Press-Release_6-Oct-2016.pdf|title=AAHMS announces its second scientific meeting and induction of new fellows|publisher=Australian Academy of Health and Medical Sciences |accessdate=14 October 2016}}</ref>
*2017 Victoria Prize for Science & Innovation (Joint with Geoff Lindeman) <ref>{{cite web|url=https://www.veski.org.au/JaneVisvader_GeoffreyLindeman#:~:text=2017%20Victoria%20Prize%20for%20Science,basic%20discoveries%20to%20the%20clinic.|title=Professor Jane Visvader&Professor Geoffrey Lindeman 2017 Victoria Prize for Science & Innovation|accessdate=2021-02-09}}</ref>
*2020 [[Fellow of the Royal Society]] (FRS).<ref>{{cite web|url=https://royalsociety.org/people/Jane-Visvader-25404/|title=Jane Visvader|publisher=Royal Society|accessdate= 20 September 2020}}</ref>
*2022 Ziskin Prize, Stand Up to Cancer (joint award) <ref name="auto1">{{cite web | url=https://www.wehi.edu.au/researcher/jane-visvader/ | title=Prof Jane Visvader }}</ref>
*2022 Fellow of the American Society of Cancer Research (AACR) Academy <ref name="auto1"/>
*2024 Australia Academy of Health and Medical Sciences Outstanding Female Researcher Medal [https://www.wehi.edu.au/news/outstanding-breast-cancer-researcher-honoured/ [19<nowiki>]</nowiki>]

== Selected publications ==
*{{cite journal|last1=Rios |first1=AC|last2=Fu |first2=NY|last3=Lindeman |first3=GJ|last4=Visvader |first4=JE| title=In situ identification of bipotent stem cells in the mammary gland|journal=Nature|date=20 February 2014 |volume=506|issue=7488 |pages=322–7|doi=10.1038/nature12948 |pmid=24463516|bibcode=2014Natur.506..322R }}
*Nolan E, Vaillant F, Branstetter D, Pal B, Giner G, Whitehead L, Lok SW, Mann GB, Rohrbach K, Huang LY, Soriano R, Smyth GK, Dougall WC, '''Visvader JE*''' and Lindeman GJ*. (2016) ''RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers''. Nat Med. 2016 Jun 20. doi: 10.1038/nm.4118. PMID: 27322743 equal senior author
*Fu NY, Rios AC, Pal B, Law C, Jamieson P, Liu R, Vaillant F, Jackling F, Liu KH, Smyth GK, Lindeman GJ, Ritchie ME, and '''Visvader JE'''. ''Identification of quiescent and spatially-restricted mammary stem cells that are hormone responsive''. Nature Cell Biol. 2017 19(3):164-176 PMID: 28192422
*Rios AC, Capaldo BD, Vaillant F, Pal B, van Ineveld R, Dawson CA, Chen Y, Nolan E, Fu NY; 3DTCLSM Group, Jackling FC, Devi S, Clouston D, Whitehead L, Smyth GK, Mueller SN, Lindeman GJ, '''Visvader JE'''. ''Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging.'' Cancer Cell. 2019 35(4), 618-632 PMID: 31185217
*Dawson CA, Pal B, Vaillant F, Gandolfo LC, Liu Z, Bleriot C, Ginhoux F, Smyth GK, Lindeman GJ, Mueller SN, Rios AC, '''Visvader JE.''' ''Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling''. Nature Cell Biol. 2020 22(5), 546-558. PMID: 32341550
*Pal B, Chen Y, Vaillant F, Capaldo BD, Joyce R, Song X, Bryant VL, Penington JS, Di Stephano L, Tubau Ribera N, Wilcox S, Mann, GB, kConFab, Papenfuss AT, Lindeman GJ, Smyth GK*, '''Visvader JE*'''. ''A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast.'' EMBO J. 2021 40(11): e107333 PMID: 33950524 *equal senior authors


==References==
==References==
{{reflist}}
{{reflist}}
{{FRS 2020}}
{{authority control}}


{{Persondata
| NAME = Visvader, Jane
| ALTERNATIVE NAMES =
| SHORT DESCRIPTION = Australian academic
| DATE OF BIRTH =
| PLACE OF BIRTH =
| DATE OF DEATH =
| PLACE OF DEATH =
}}
{{DEFAULTSORT:Visvader, Jane}}
{{DEFAULTSORT:Visvader, Jane}}
[[Category:Year of birth missing (living people)]]
[[Category:Living people]]
[[Category:Australian women academics]]
[[Category:Australian women academics]]
[[Category:Fellows of the Australian Academy of Science]]
[[Category:Fellows of the Australian Academy of Science]]
[[Category:Australian women scientists]]
[[Category:Australian women scientists]]
[[Category:Living people]]
[[Category:Year of birth missing (living people)]]
[[Category:Wikibomb2014]]
[[Category:Cancer researchers]]
[[Category:Cancer researchers]]
[[Category:Fellows of the Australian Academy of Health and Medical Sciences]]
[[Category:Female fellows of the Royal Society]]
[[Category:WEHI alumni]]

Latest revision as of 00:06, 3 October 2024

Jane Visvader
FRS FAA FAHMS
Alma materUniversity of Adelaide
Scientific career
InstitutionsWalter and Eliza Hall Institute of Medical Research
Salk Institute

Jane Visvader is a scientist specialising in breast cancer research who works for the Walter and Eliza Hall Institute in Melbourne, Australia. She is the joint head of the Breast Cancer Laboratory with Geoff Lindeman.[1]

Education

[edit]

Visvader holds a PhD in Biochemistry from the University of Adelaide having studied structure and function of citrus exocortis viroid[2]

Career and research

[edit]

After her PhD [3] in the Department of Biochemistry at the University of Adelaide , she was a postdoctoral researcher with Inder Verma (Salk Institute, San Diego) and Jerry Adams (Walter and Eliza Hall Institute (WEHI)).[4] She worked at the Children's Hospital/Harvard Medical School in Boston before returning to Victoria in 1997 to establish a Breast Cancer Laboratory at WEHI.[4]

Visvader has published work investigating the role of cells of origin in cancer[5] and in particular focuses on the role of stem cells,[6][7] which she believes may be a key to understanding breast cancer.[8]

Visvader is a board member of the Cancer Council Victoria, Medical & Scientific Committee.[9]

Patents

[edit]

Visvader is a named inventor on five patents relating to cancer research focused on stem cell isolation and diagnostics.[10]

  • Method Of Cell Isolation, Application number: 20080038230
  • Differentiation and/or proliferation modulating agents and uses therefor, Application number: 20060166917
  • Novel phosphoprotein, Application number: 20060148032
  • Method of diagnosis and treatment and agents useful for same, Application number: 20050048528
  • Differentiation and/or proliferation modulating agents and uses therefor, Application number: 20030175971

Awards and recognition

[edit]

Selected publications

[edit]
  • Rios, AC; Fu, NY; Lindeman, GJ; Visvader, JE (20 February 2014). "In situ identification of bipotent stem cells in the mammary gland". Nature. 506 (7488): 322–7. Bibcode:2014Natur.506..322R. doi:10.1038/nature12948. PMID 24463516.
  • Nolan E, Vaillant F, Branstetter D, Pal B, Giner G, Whitehead L, Lok SW, Mann GB, Rohrbach K, Huang LY, Soriano R, Smyth GK, Dougall WC, Visvader JE* and Lindeman GJ*. (2016) RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers. Nat Med. 2016 Jun 20. doi: 10.1038/nm.4118. PMID: 27322743 equal senior author
  • Fu NY, Rios AC, Pal B, Law C, Jamieson P, Liu R, Vaillant F, Jackling F, Liu KH, Smyth GK, Lindeman GJ, Ritchie ME, and Visvader JE. Identification of quiescent and spatially-restricted mammary stem cells that are hormone responsive. Nature Cell Biol. 2017 19(3):164-176 PMID: 28192422
  • Rios AC, Capaldo BD, Vaillant F, Pal B, van Ineveld R, Dawson CA, Chen Y, Nolan E, Fu NY; 3DTCLSM Group, Jackling FC, Devi S, Clouston D, Whitehead L, Smyth GK, Mueller SN, Lindeman GJ, Visvader JE. Intraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D Imaging. Cancer Cell. 2019 35(4), 618-632 PMID: 31185217
  • Dawson CA, Pal B, Vaillant F, Gandolfo LC, Liu Z, Bleriot C, Ginhoux F, Smyth GK, Lindeman GJ, Mueller SN, Rios AC, Visvader JE. Tissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling. Nature Cell Biol. 2020 22(5), 546-558. PMID: 32341550
  • Pal B, Chen Y, Vaillant F, Capaldo BD, Joyce R, Song X, Bryant VL, Penington JS, Di Stephano L, Tubau Ribera N, Wilcox S, Mann, GB, kConFab, Papenfuss AT, Lindeman GJ, Smyth GK*, Visvader JE*. A single-cell RNA expression atlas of normal, preneoplastic and tumorigenic states in the human breast. EMBO J. 2021 40(11): e107333 PMID: 33950524 *equal senior authors

References

[edit]
  1. ^ "Professor Jane Visvader". Retrieved 14 August 2014.
  2. ^ "Structure and function of citrus exocortis viroid / by Jane Ellen Visvader. - Version details - Trove". Trove.nla.gov.au. 28 December 2006. Retrieved 14 August 2014.
  3. ^ "Professor Jane Visvader".
  4. ^ a b c "News | Royal Society of Victoria | Promoting Science and Science Education". Royalsocietyvictoria.org.au. Retrieved 14 August 2014.
  5. ^ Visvader, Jane E. (2011). "Cells of origin in cancer". Nature. 469 (7330): 314–322. Bibcode:2011Natur.469..314V. doi:10.1038/nature09781. PMID 21248838. S2CID 4418009.
  6. ^ Rios, Anne C.; Fu, Nai Yang; Lindeman, Geoffrey J.; Visvader, Jane E. (2014). "In situ identification of bipotent stem cells in the mammary gland". Nature. 506 (7488): 322–327. Bibcode:2014Natur.506..322R. doi:10.1038/nature12948. PMID 24463516. S2CID 205237171.
  7. ^ Visvader, Jane E.; Lindeman, Geoffrey J. (2012). "Cancer Stem Cells: Current Status and Evolving Complexities". Cell Stem Cell. 10 (6): 717–728. doi:10.1016/j.stem.2012.05.007. PMID 22704512.
  8. ^ Giovanni Valenti (11 January 2012). "Interview with Jane Visvader: stem cells in the breast | Europe's stem cell hub". Nature. 439 (7072): 84–88. doi:10.1038/nature04372. PMID 16397499. S2CID 2662840. Retrieved 14 August 2014.
  9. ^ "Board of Directors - Cancer Council Victoria".
  10. ^ "Patents by Inventor Jane Visvader - Justia Patents Database". Patents.justia.com. Retrieved 14 August 2014.
  11. ^ "GSK Alumni Members". Retrieved 9 February 2021.
  12. ^ "Fellowship list - Australian Academy of Science". Science.org.au. Retrieved 14 August 2014.
  13. ^ "Top NHMRC research recognised". Retrieved 9 February 2021.
  14. ^ "THE 2016 LEMBERG MEDAL: JANE VISVADER". Retrieved 9 February 2021.
  15. ^ "AAHMS announces its second scientific meeting and induction of new fellows" (PDF). Australian Academy of Health and Medical Sciences. Retrieved 14 October 2016.
  16. ^ "Professor Jane Visvader&Professor Geoffrey Lindeman 2017 Victoria Prize for Science & Innovation". Retrieved 9 February 2021.
  17. ^ "Jane Visvader". Royal Society. Retrieved 20 September 2020.
  18. ^ a b "Prof Jane Visvader".
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