Glycyrrhizol: Difference between revisions
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{{chembox |
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| verifiedrevid = 408565402 |
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| Name=Glycyrrhizol A |
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| ImageFile = Glycyrrhizol A.png |
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| ImageSize = 200px |
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| PIN = 1-Methoxy-2,8-bis(3-methylbut-2-en-1-yl)-6''H''-[1]benzofuro[3,2-''c''] [1]benzopyran-3,9-diol |
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| OtherNames = |
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|Section1={{Chembox Identifiers |
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| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} |
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| ChemSpiderID = 9721048 |
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| InChI = 1/C26H28O5/c1-14(2)6-8-16-10-18-19-13-30-23-12-21(28)17(9-7-15(3)4)25(29-5)24(23)26(19)31-22(18)11-20(16)27/h6-7,10-12,27-28H,8-9,13H2,1-5H3 |
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| InChIKey = CBPFOSMNDISZLV-UHFFFAOYAJ |
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| ChEBI_Ref = {{ebicite|changed|EBI}} |
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| ChEBI = 65976 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 522282 |
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| StdInChI_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChI = 1S/C26H28O5/c1-14(2)6-8-16-10-18-19-13-30-23-12-21(28)17(9-7-15(3)4)25(29-5)24(23)26(19)31-22(18)11-20(16)27/h6-7,10-12,27-28H,8-9,13H2,1-5H3 |
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| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} |
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| StdInChIKey = CBPFOSMNDISZLV-UHFFFAOYSA-N |
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| CASNo_Ref = {{cascite|correct|??}} |
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| CASNo = 877373-00-7 |
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| UNII_Ref = {{fdacite|correct|FDA}} |
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| UNII = 84L7S5MVN5 |
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| PubChem = 11546269 |
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| SMILES = o2c1c(cc(c(O)c1)C\C=C(/C)C)c3c2c4c(OC)c(c(O)cc4OC3)C\C=C(/C)C |
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|Section2={{Chembox Properties |
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| Formula = C<sub>26</sub>H<sub>28</sub>O<sub>5</sub> |
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| MolarMass = 420.50 g/mol |
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| Appearance = |
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| Solubility = }} |
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|Section3={{Chembox Hazards |
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| FlashPt = |
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| AutoignitionPt = }} |
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}} |
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Recent studies by scientists from [[University of California, Los Angeles|UCLA]] have suggested that these compounds have [[antibacterial]] properties.<sup>[1]</sup> The strongest antibacterial activity was observed against ''[[Streptococcus mutans]]'', an organism known to cause tooth decay in humans. |
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It may has ''[[in vitro]]'' [[antibacterial]] properties.<ref name = He>{{cite journal | vauthors= He J, Chen L, Shi W, ((Lu Q-Y)) | title=Antibacterial Compounds from ''Glycyrrhiza uralensis'' | journal= Journal of Natural Products | volume=69| issue=1 | year=2006 | pages=121–124 | doi=10.1021/np058069d | pmid= 16441081| citeseerx=10.1.1.552.7335 }}</ref> In one study, the strongest antibacterial activity was observed against ''[[Streptococcus mutans]]'', an organism known to cause tooth decay in humans.<ref name = He/> |
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[[image:Glycyrrhizol-structure.gif|center|Structure of Glycyrrhizol A]] |
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==References== |
==References== |
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{{reflist}} |
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* <sup>[1]</sup> {{cite journal | author= He J, Chen L, Shi W, Lu, Q-Y | title=Antibacterial Compounds from ''Glycyrrhiza uralensis'' | journal=[[Journal of Natural Products]] | volume=69| issue=1 | year=2006 | pages=121-124 | id=}} |
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{{Pterocarpan}} |
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==External links== |
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{{ChemicalSources}} |
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[[Category:Antibiotics]] |
[[Category:Antibiotics]] |
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[[Category:Hydroxyarenes]] |
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[[Category:Methoxy compounds]] |
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{{ |
{{aromatic-stub}} |
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Latest revision as of 12:01, 21 October 2024
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| Names | |
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| Preferred IUPAC name
1-Methoxy-2,8-bis(3-methylbut-2-en-1-yl)-6H-[1]benzofuro[3,2-c] [1]benzopyran-3,9-diol | |
| Identifiers | |
3D model (JSmol)
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| ChEBI | |
| ChEMBL | |
| ChemSpider | |
PubChem CID
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| UNII | |
CompTox Dashboard (EPA)
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| Properties | |
| C26H28O5 | |
| Molar mass | 420.50 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Glycyrrhizol A is a prenylated pterocarpan and an isoflavonoid derivative. It is a compound isolated from the root of the Chinese licorice plant (Glycyrrhiza uralensis).[citation needed]
It may has in vitro antibacterial properties.[1] In one study, the strongest antibacterial activity was observed against Streptococcus mutans, an organism known to cause tooth decay in humans.[1]
References
[edit]- ^ a b He J, Chen L, Shi W, Lu Q-Y (2006). "Antibacterial Compounds from Glycyrrhiza uralensis". Journal of Natural Products. 69 (1): 121–124. CiteSeerX 10.1.1.552.7335. doi:10.1021/np058069d. PMID 16441081.
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