MCI Screen: Difference between revisions
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==MCI Screen== |
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{{short description|Neuropsycholigical test}} |
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| ⚫ | The |
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| name = MCI Screen |
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| purpose =check mild cognitive impairment |
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The '''MCI Screen''' is a brief [[neuropsychological test]] checking for [[mild cognitive impairment]] (MCI). |
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| ⚫ | The protocol consists of an immediate recall task, a triadic comparison task, a judgment task, a delayed free recall task, a cued-recall task, and a rehearsed recall task. It is scored using [[correspondence analysis]] and statistical methods for differentiating normal [[cognitive function]] from [[Mild cognitive impairment]]. The methodology for scoring the MCI Screen was developed by the [https://embic.us/ Embic Corporation] (formerly Medical Care Corporation), a privately held California Corporation. |
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It was derived from the protocol of the CERAD 10-word recall test. |
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==Validation== |
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The MCI Screen was validated in a study on 471 community dwelling adults whose scores on the Clinical Dementia Rating Scale ranged from 0 (normal: N=119), 0.5 (mild cognitive impairment: N=95), to 1 (mild dementia: N=257). The MCI Screen showed overall accuracy of 98% with sensitivity of 97% for mild cognitive impairment or mild dementia, and 88% specificity for normal aging. The accuracy of the MCI Screen has been published in the Proceedings of the National Academy of Sciences: [http://web1.mccare.com/pdf/PNAS_Shankle05.pdf Methods to Improve the Detection of Mild Cognitive Impairment]. |
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The MCI Screen was validated in a study on 471 community dwelling adults whose scores on the [[Clinical Dementia Rating Scale]] ranged from 0 (normal: N=119), 0.5 (mild cognitive impairment: N=95), to 1 (mild dementia: N=257). According to a 2005 publication in [[Proceedings of the National Academy of Sciences of the United States of America|The Proceedings of the National Academy of Sciences]], the MCI Screen has overall accuracy of 98% with sensitivity of 97% for mild cognitive impairment or mild dementia, and 88% specificity for normal aging.<ref>Shankle WR, Romney AK, Hara J, et al. Method to improve the detection of mild cognitive impairment. PNAS. 2005; 102(13): 4919-24.</ref> Clinical studies in the USA have shown that the MCI Screen detects early-stage, memory loss due to multiple underlying medical conditions including [[Alzheimer's disease]], cerebrovascular disease, and others.<ref>Trenkle D, Shankle WR, Azen SP. Detecting Cognitive Impairment in Primary Care: Performance Assessment of Three Screening Instruments. Journal of Alzheimer's Disease. 2007; 11(3):323-335.</ref> Japan based studies have demonstrated cross-cultural validity of the MCI Screen in clinical and academic settings with accuracy levels equal to those in the USA.<ref>Ai Cho, Mika Sugimura, Seigo Nakano, Tatsuo Yamada. Early Detection and Diagnosis of Demented Disorders Using the MCI Screen and Neuroimaging; The Japanese Journal of Clinical and Experimental Medicine. 2007; 84(8):1152-1160.</ref><ref>Ai Cho; Mika Sugimura; Seigo Nakano, Tatsuo Yamada. The Japanese MCI Screen for Early Detection of Alzheimer’s Disease and Related Disorders. The American Journal of Alzheimer’s Disease and Other Dementias. 2008; June/July (in press).</ref> |
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{{Reflist}} |
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{{Neuropsychology tests}} |
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==Clinical Validation== |
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The MCI Screen is used in clinical practice to identify early stage memory loss due to underlying medical conditions including Alzheimer's disease, cerebrovascular disease, and others<ref>Trenkle D, Shankle WR, Azen SP. Detecting Cognitive Impairment in Primary Care: Performance Assessment of Three Screening Instruments. Journal of Alzheimer's Disease. 2007; 11(3):323-335. [http://web1.mccare.com/pdf/JAD_Trenkle07_MCIS.pdf Detecting Cognitive Impairment in Primary Care]. |
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[[Category:Neuropsychological tests]] |
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[[Category:Cognitive tests]] |
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[[Category:Memory tests]] |
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Latest revision as of 12:22, 25 October 2024
 | This article contains promotional content. (April 2014) |
| MCI Screen | |
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| Purpose | check mild cognitive impairment |
The MCI Screen is a brief neuropsychological test checking for mild cognitive impairment (MCI).
The protocol consists of an immediate recall task, a triadic comparison task, a judgment task, a delayed free recall task, a cued-recall task, and a rehearsed recall task. It is scored using correspondence analysis and statistical methods for differentiating normal cognitive function from Mild cognitive impairment. The methodology for scoring the MCI Screen was developed by the Embic Corporation (formerly Medical Care Corporation), a privately held California Corporation.
It was derived from the protocol of the CERAD 10-word recall test.
Validation
[edit]The MCI Screen was validated in a study on 471 community dwelling adults whose scores on the Clinical Dementia Rating Scale ranged from 0 (normal: N=119), 0.5 (mild cognitive impairment: N=95), to 1 (mild dementia: N=257). According to a 2005 publication in The Proceedings of the National Academy of Sciences, the MCI Screen has overall accuracy of 98% with sensitivity of 97% for mild cognitive impairment or mild dementia, and 88% specificity for normal aging.[1] Clinical studies in the USA have shown that the MCI Screen detects early-stage, memory loss due to multiple underlying medical conditions including Alzheimer's disease, cerebrovascular disease, and others.[2] Japan based studies have demonstrated cross-cultural validity of the MCI Screen in clinical and academic settings with accuracy levels equal to those in the USA.[3][4]
References
[edit]- ^ Shankle WR, Romney AK, Hara J, et al. Method to improve the detection of mild cognitive impairment. PNAS. 2005; 102(13): 4919-24.
- ^ Trenkle D, Shankle WR, Azen SP. Detecting Cognitive Impairment in Primary Care: Performance Assessment of Three Screening Instruments. Journal of Alzheimer's Disease. 2007; 11(3):323-335.
- ^ Ai Cho, Mika Sugimura, Seigo Nakano, Tatsuo Yamada. Early Detection and Diagnosis of Demented Disorders Using the MCI Screen and Neuroimaging; The Japanese Journal of Clinical and Experimental Medicine. 2007; 84(8):1152-1160.
- ^ Ai Cho; Mika Sugimura; Seigo Nakano, Tatsuo Yamada. The Japanese MCI Screen for Early Detection of Alzheimer’s Disease and Related Disorders. The American Journal of Alzheimer’s Disease and Other Dementias. 2008; June/July (in press).