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Importing Wikidata short description: "Protein-coding gene in the species Homo sapiens"
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{{Short description|Protein-coding gene in the species Homo sapiens}}
{{Short description|Protein-coding gene in the species Homo sapiens}}
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{{Infobox_gene}}
{{Infobox_gene}}
'''Keratin, type I cuticular Ha6''' is a [[protein]] that in humans is encoded by the ''KRT36'' [[gene]].<ref name="pmid9756910">{{cite journal |vauthors=Rogers MA, Winter H, Wolf C, Heck M, Schweizer J | title = Characterization of a 190-kilobase pair domain of human type I hair keratin genes | journal = J Biol Chem | volume = 273 | issue = 41 | pages = 26683–91 |date=Nov 1998 | pmid = 9756910 | doi =10.1074/jbc.273.41.26683 | doi-access = free }}</ref><ref name="pmid16831889">{{cite journal |vauthors=Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW | title = New consensus nomenclature for mammalian keratins | journal = J Cell Biol | volume = 174 | issue = 2 | pages = 169–74 |date=Jul 2006 | pmid = 16831889 | pmc = 2064177 | doi = 10.1083/jcb.200603161 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: KRT36 keratin 36| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8689}}</ref>
'''Keratin, type I cuticular Ha6''' is a [[protein]] that in humans is encoded by the ''KRT36'' [[gene]].<ref name="pmid9756910">{{cite journal |vauthors=Rogers MA, Winter H, Wolf C, Heck M, Schweizer J | title = Characterization of a 190-kilobase pair domain of human type I hair keratin genes | journal = J Biol Chem | volume = 273 | issue = 41 | pages = 26683–91 |date=Nov 1998 | pmid = 9756910 | doi =10.1074/jbc.273.41.26683 | doi-access = free }}</ref><ref name="pmid16831889">{{cite journal |vauthors=Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW | title = New consensus nomenclature for mammalian keratins | journal = J Cell Biol | volume = 174 | issue = 2 | pages = 169–74 |date=Jul 2006 | pmid = 16831889 | pmc = 2064177 | doi = 10.1083/jcb.200603161 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: KRT36 keratin 36| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8689}}</ref>


The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription.<ref name="entrez">{{cite web | title = Entrez Gene: KRT36 keratin 36| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=8689}}</ref>
The protein encoded by this gene is a member of the [[keratin]] gene family. This [[type I hair keratin]] is an acidic protein which [[heterodimerize]]s with [[type II keratin]]s to form hair and nails. The type I hair keratins are [[Gene cluster|clustered]] in a region of [[chromosome 17]]q21.2 and have the same direction of transcription.<ref name="entrez"/>


==References==
==References==

Latest revision as of 09:34, 2 November 2024

KRT36
Identifiers
AliasesKRT36, HA6, KRTHA6, hHa6, keratin 36
External IDsOMIM: 604540; MGI: 109364; HomoloGene: 88459; GeneCards: KRT36; OMA:KRT36 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_003771

NM_001174099
NM_008472

RefSeq (protein)

NP_003762

NP_001167570

Location (UCSC)Chr 17: 41.49 – 41.49 MbChr 11: 99.99 – 100 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Keratin, type I cuticular Ha6 is a protein that in humans is encoded by the KRT36 gene.[5][6][7]

The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q21.2 and have the same direction of transcription.[7]

References

[edit]
  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000126337Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000020916Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Rogers MA, Winter H, Wolf C, Heck M, Schweizer J (Nov 1998). "Characterization of a 190-kilobase pair domain of human type I hair keratin genes". J Biol Chem. 273 (41): 26683–91. doi:10.1074/jbc.273.41.26683. PMID 9756910.
  6. ^ Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW (Jul 2006). "New consensus nomenclature for mammalian keratins". J Cell Biol. 174 (2): 169–74. doi:10.1083/jcb.200603161. PMC 2064177. PMID 16831889.
  7. ^ a b "Entrez Gene: KRT36 keratin 36".

Further reading

[edit]