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{{Short description|Brand name for a cough and pain medicine}}
{{Infobox drug
{{Infobox drug
| drug_name =
| drug_name =
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| image2 = Chlorphenamine.svg
| image2 = Chlorphenamine.svg
| alt =
| alt =
| caption = Chemical structures of dextromethorphan (top) and chlorphenamine
| caption = Chemical structures of dextromethorphan (top) and chlorpheniramine
| component1 = Dextromethorphan
| component1 = Dextromethorphan
| class1 = [[cough suppressant]]
| class1 = [[cough suppressant]]
| component2 = Chlorphenamine
| component2 = Chlorpheniramine
| class2 = [[antihistamine]]
| class2 = [[antihistamine]]
<!-- Clinical data -->
<!-- Clinical data -->
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| excretion =
| excretion =
<!-- Identifiers -->
<!-- Identifiers -->
| CAS_number_Ref = {{cascite|correct|CAS}}
| CAS_number =
| CAS_number = 125-71-3
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = 7355X3ROTS
| class =
| class =
| ATCvet =
| ATCvet =
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}}
}}


'''Coricidin''', '''Coricidin 'D'''' (decongestant), or '''Coricidin HBP''' (for '''h'''igh '''b'''lood '''p'''ressure), is the name of a drug marketed by [[Schering-Plough]] that contains [[dextromethorphan]] (a [[cough suppressant]]) and [[chlorpheniramine]] maleate (an [[antihistamine]]). Varieties of Coricidin may also contain [[acetaminophen]] (an [[analgesic]]/[[antipyretic]]) and [[guaifenesin]] (an [[expectorant]]).
'''Coricidin''', '''Coricidin 'D'''' (decongestant), or '''Coricidin HBP''' (for '''h'''igh '''b'''lood '''p'''ressure), is the name of an [[Over-the-counter drug|over-the-counter]] cough and cold drug containing [[dextromethorphan]] (a [[cough suppressant]]) and [[chlorpheniramine]] maleate (an [[antihistamine]]).<ref>{{cite web |title=Label: Coricidin HBP Cold and Flu |url=https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=763a5334-a741-4678-9947-603776622450 |publisher=[[DailyMed]] |date=December 30, 2021}}</ref> Introduced by [[Schering-Plough]] in 1949 as one of the first antihistamines, it is now owned by Bayer.<ref>{{cite web |title=Coricidin Meaning |url=https://www.dictionary.com/e/pop-culture/coricidin/ |publisher=[[Dictionary.com]] |date=March 12, 2018}}</ref><ref>{{cite web |title=Schering-Plough profile |url=https://www.adbrands.net/archive/us/scheringplough_us_p.htm |publisher=adbrands.net |date=June 24, 2016}}</ref> Varieties of Coricidin may also contain [[acetaminophen]] (an [[analgesic]]/[[antipyretic]]) and [[guaifenesin]] (an [[expectorant]]).


==Medicinal use==
==Medicinal use==
Coricidin is used to alleviate coughs and includes chlorpheniramine for people with high blood pressure. Other versions of Coricidin are used to reduce fever or as an expectorant. Side effects can include [[diarrhea]] and [[hallucination]].<ref>[http://www.webmd.com/drugs/2/drug-2247/coricidin-hbp-cough-and-cold-oral/details/list-sideeffects "Coricidin HBP Cough and Cold"], WebMD. Retrieved 7 January 2017.</ref>
Coricidin is used to alleviate common cold symptoms such as coughs and congestion. Other versions of Coricidin are used to reduce fever or as an expectorant, while Coricidin HBP includes chlorpheniramine for people with high blood pressure. Side effects can include [[diarrhea]] and [[hallucination]].<ref>[http://www.webmd.com/drugs/2/drug-2247/coricidin-hbp-cough-and-cold-oral/details/list-sideeffects "Coricidin HBP Cough and Cold"], WebMD. Retrieved 7 January 2017.</ref>


==Recreational use==
==Recreational use==
{{See also|Recreational use of dextromethorphan}}
{{See also|Recreational use of dextromethorphan}}
Coricidin is sometimes used in high doses as a recreational drug{{cn|date=September 2017}} because it contains the [[dissociative]] [[dextromethorphan]]. In this context, Coricidin is referred to as C's, red devils (red D's), Skittles, trips,<ref>{{cite journal|last=Henigig|first=Christian}}</ref>{{full|date=September 2017}} or triple C's.
Coricidin, in its cough & cold formulation, is sometimes used in high doses as a recreational drug because it contains the [[dissociative]] [[dextromethorphan]]. In this context, Coricidin is referred to as Cs, Red Devils (Red Ds), Triple Cs, Skittles, trips, or china red.<ref name="pmid32393072">{{cite journal | vauthors = Silva AR, Dinis-Oliveira RJ | title = Pharmacokinetics and pharmacodynamics of dextromethorphan: clinical and forensic aspects | journal = Drug Metabolism Reviews | volume = 52 | issue = 2 | pages = 258–282 | date = May 2020 | pmid = 32393072 | doi = 10.1080/03602532.2020.1758712 }}</ref>


⚫
==In popular culture==
Long-term recreational abuse of dextromethorphan can result in [[psychosis]] and [[erectile dysfunction]].<ref>[http://www.poisoncentertampa.org/poison-topics/substances-of-abuse/ "Substances of Abuse"], Florida Poison Information Center - Tampa. Retrieved 7 jan 2017</ref>
⚫
[[File:Coricidinslides.jpg|thumb|A selection of guitar slides, with two Coricidin bottles (second and third from left)]]


⚫
An empty glass Coricidin bottle was adopted as a guitar slide by blues-rock guitarist [[Duane Allman]] while teaching himself [[slide guitar]] in the late 1960s.<ref>{{cite web |title=Duane Allman's Coricidin Bottle Slide Returns Back to Allman Family After 40 Years |url=https://jambands.com/news/2013/05/22/duane-allman-s-coricidin-bottle-slide-returns-back-to-allman-family-after-40-years/ |publisher=[[Zenbu Media|Jambands]] |date=May 22, 2013}}</ref> Allman found it to be just the right size and shape for the purpose after receiving two birthday gifts from his brother, [[Gregg Allman|Gregg]]: a copy of [[Taj Mahal (album)|Taj Mahal's debut album]], with its version of "[[Statesboro Blues]]", and a bottle of Coricidin for a cold he had gotten.<ref>{{cite web | vauthors = Furlong P |title=Gregg and Duane Were Brothers |url=http://www.kuvo.org/post/gregg-and-duane-were-brothers |website=kuvo.org |publisher=[[KUVO]] |date=February 17, 2014|quote=It was his birthday (and he had a cold), so I went and bought him a bottle of Coricidin. . . Then I went by the record store and got that first Taj Mahal record, with all the butterflies on the cover and him sitting on a rocking chair. We’d played with Taj before, borrowed an amplifier from him. So I got Duane that record and the pills.” Gregg took the gifts over to Duane’s and left them on his front porch. Twenty-four hours later, Duane called, “Get over here quick, babybrah (for baby brother). Quick, man!” Duane had taken the pills out of the bottle and removed the label. “He put on that Taj Mahal record, with Jesse Ed Davis playing slide on ‘Statesboro Blues,’ and started playing along with it. When I left those pills by his door, he hadn’t known how to play slide. From the moment that Duane put that Coricidin bottle on his ring finger, he was a natural.}}</ref><ref>{{cite web |title=The Allman Brothers Band |url=https://www.pressreader.com/australia/guitar-techniques/20150807/281608124142948 |publisher=Guitar Techniques |date=August 7, 2015|via=[[PressReader]]}}</ref> Other prominent slide guitarists, such as [[Derek Trucks]] (a later member of the Allman Brothers Band), [[Ray Wylie Hubbard]], [[Rory Gallagher]], [[J. D. Simo]], and [[Gary Rossington]] also adopted the Coricidin bottle as a slide.<ref>
⚫
==Use in popular music==
⚫
*'''Derek Trucks'''—{{cite magazine |author1=Guitar Player Staff |title=Derek Trucks: Slide Sans Frontiers |url=https://www.guitarplayer.com/players/derek-trucks-slide-sans-frontiers |magazine=Guitar Player |date=March 14, 2006}}
⚫
[[File:Coricidinslides.jpg|thumb|right|Two Coricidin bottles used as guitar slides (second and third from left)]]
*'''Ray Wylie Hubbard'''—{{cite web | vauthors = Dansby A |title=Q&A: Ray Wylie Hubbard |url=http://lonestarmusicmagazine.com/qa-ray-wylie-hubbard-3/ |publisher=Lone Star Music Magazine |date=March 1, 2012}}
⚫
In the late 1960s, blues-rock guitarist [[Duane Allman]] began using an empty glass Coricidin bottle as a [[slide guitar|guitar slide]], finding it to be just the right size and shape for this purpose.<ref>{{cite web |title=Duane Allman’s Coricidin Bottle Slide Returns Back to Allman Family After 40 Years |url=https://jambands.com/news/2013/05/22/duane-allman-s-coricidin-bottle-slide-returns-back-to-allman-family-after-40-years/ |publisher=[[Zenbu Media|Jambands]] |date=May 22, 2013}}</ref> Allman learned to play slide guitar when he received two birthday gifts from his brother, [[Gregg Allman|Gregg]]: a copy of [[Taj Mahal (album)|Taj Mahal's debut album]], with its version of "[[Statesboro Blues]]", and a bottle of Coricidin pills (as Duane had a cold that day).<ref>{{cite web |last1=Furlong |first1=Peter |title=Gregg and Duane Were Brothers |url=http://www.kuvo.org/post/gregg-and-duane-were-brothers |website=kuvo.org |publisher=[[KUVO]] |date=February 17, 2014|quote=It was his birthday (and he had a cold), so I went and bought him a bottle of Coricidin. . . Then I went by the record store and got that first Taj Mahal record, with all the butterflies on the cover and him sitting on a rocking chair. We’d played with Taj before, borrowed an amplifier from him. So I got Duane that record and the pills.” Gregg took the gifts over to Duane’s and left them on his front porch. Twenty-four hours later, Duane called, “Get over here quick, babybrah (for baby brother). Quick, man!” Duane had taken the pills out of the bottle and removed the label. “He put on that Taj Mahal record, with Jesse Ed Davis playing slide on ‘Statesboro Blues,’ and started playing along with it. When I left those pills by his door, he hadn’t known how to play slide. From the moment that Duane put that Coricidin bottle on his ring finger, he was a natural.}}</ref><ref>{{cite web |title=The Allman Brothers Band |url=https://www.pressreader.com/australia/guitar-techniques/20150807/281608124142948 |publisher=''Guitar Techniques'' |date=August 7, 2015|via=[[PressReader]]}}</ref> Other prominent slide guitarists, such as [[Derek Trucks]] (a later member of the Allman Brothers Band), [[Ray Wylie Hubbard]], [[Rory Gallagher]], [[J. D. Simo]], and [[Gary Rossington]] also adopted the Coricidin bottle as a slide.<ref>
⚫
*'''Rory Gallagher'''—{{cite book | vauthors = Connaughton M |title=Rory Gallagher: His Life and Times |date=2012 |publisher=The Collins Press |isbn=9781848899803 |url=https://books.google.com/books?id=A-xFDwAAQBAJ&q=coricidin+bottle++Rory+Gallagher&pg=PT246 |language=en}}
⚫
*'''Derek Trucks'''—{{cite web |author1=Guitar Player Staff |title=Derek Trucks: Slide Sans Frontiers |url=https://www.guitarplayer.com/players/derek-trucks-slide-sans-frontiers |publisher=''Guitar Player'' |date=March 14, 2006}}
*'''Ray Wylie Hubbard'''—{{cite web |last1=Dansby |first1=Andrew |title=Q&A: Ray Wylie Hubbard |url=http://lonestarmusicmagazine.com/qa-ray-wylie-hubbard-3/ |publisher=''Lone Star Music Magazine'' |date=March 1, 2012}}
*'''J.D. Simo'''—{{cite magazine | vauthors = Ross M |title=J.D. Simo Brings the Blues Back Home on on(sic)'Let Love Show the Way' |url=https://www.guitarplayer.com/players/jd-simo-brings-the-blues-back-home-on-on-let-love-show-the-way |magazine=Guitar Player |date=February 17, 2016}}
⚫
*'''Gary Rossington'''—{{cite magazine | vauthors = Scoppa B |title=The Allman Brothers: "We were stretching the limits of what had been done in rock'n'roll" |url=https://www.uncut.co.uk/features/the-allman-brothers-we-were-stretching-the-limits-of-what-had-been-done-in-rocknroll-71765/4 |magazine=Uncut |date=November 20, 2015}}</ref>
⚫
*'''Rory Gallagher'''—{{cite book |last1=Connaughton |first1=Marcus |title=Rory Gallagher: His Life and Times |date=2012 |publisher=The Collins Press |isbn=9781848899803 |url=https://books.google.com/books?id=A-xFDwAAQBAJ&pg=PT246&lpg=PT246&dq=coricidin+bottle++Rory+Gallagher&source=bl&ots=izRmY0TvY7&sig=4odhF4I953GENCspR3qu25RdcCk&hl=en&sa=X&ved=2ahUKEwj2_dv2oqbfAhVKZKwKHfxWBUY4ChDoATAIegQIABAB#v=onepage&q=coricidin%20bottle%20%20Rory%20Gallagher&f=false |language=en}}
*'''J.D. Simo'''—{{cite web |last1=Ross |first1=Michael |title=J.D. Simo Brings the Blues Back Home on on(sic)'Let Love Show the Way' |url=https://www.guitarplayer.com/players/jd-simo-brings-the-blues-back-home-on-on-let-love-show-the-way |publisher=''Guitar Player'' |date=February 17, 2016}}
⚫
*'''Gary Rossington'''—{{cite web |last1=Scoppa |first1=Bud |title=The Allman Brothers: “We were stretching the limits of what had been done in rock’n’roll” |url=https://www.uncut.co.uk/features/the-allman-brothers-we-were-stretching-the-limits-of-what-had-been-done-in-rocknroll-71765/4 |publisher=''Uncut'' |date=November 20, 2015}}</ref>


==Notes==
==Notes==
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[[Category:Combination drugs]]
[[Category:Combination drugs]]
[[Category:Drugs developed by Schering-Plough]]
[[Category:Drugs developed by Merck & Co.]]
[[Category:Drugs developed by Bayer]]

Latest revision as of 14:42, 9 December 2024

Coricidin
Chemical structures of dextromethorphan (top) and chlorpheniramine
Combination of
Dextromethorphancough suppressant
Chlorpheniramineantihistamine
Clinical data
Trade namesCoricidin 'D'
Pharmacokinetic data
MetabolismCYP2D6 isozyme of Cytochrome P450
Identifiers
CAS Number
UNII

Coricidin, Coricidin 'D' (decongestant), or Coricidin HBP (for high blood pressure), is the name of an over-the-counter cough and cold drug containing dextromethorphan (a cough suppressant) and chlorpheniramine maleate (an antihistamine).[1] Introduced by Schering-Plough in 1949 as one of the first antihistamines, it is now owned by Bayer.[2][3] Varieties of Coricidin may also contain acetaminophen (an analgesic/antipyretic) and guaifenesin (an expectorant).

Medicinal use

[edit]

Coricidin is used to alleviate common cold symptoms such as coughs and congestion. Other versions of Coricidin are used to reduce fever or as an expectorant, while Coricidin HBP includes chlorpheniramine for people with high blood pressure. Side effects can include diarrhea and hallucination.[4]

Recreational use

[edit]
See also: Recreational use of dextromethorphan

Coricidin, in its cough & cold formulation, is sometimes used in high doses as a recreational drug because it contains the dissociative dextromethorphan. In this context, Coricidin is referred to as Cs, Red Devils (Red Ds), Triple Cs, Skittles, trips, or china red.[5]

[edit]
A selection of guitar slides, with two Coricidin bottles (second and third from left)

An empty glass Coricidin bottle was adopted as a guitar slide by blues-rock guitarist Duane Allman while teaching himself slide guitar in the late 1960s.[6] Allman found it to be just the right size and shape for the purpose after receiving two birthday gifts from his brother, Gregg: a copy of Taj Mahal's debut album, with its version of "Statesboro Blues", and a bottle of Coricidin for a cold he had gotten.[7][8] Other prominent slide guitarists, such as Derek Trucks (a later member of the Allman Brothers Band), Ray Wylie Hubbard, Rory Gallagher, J. D. Simo, and Gary Rossington also adopted the Coricidin bottle as a slide.[9]

Notes

[edit]
  1. ^ "Label: Coricidin HBP Cold and Flu". DailyMed. December 30, 2021.
  2. ^ "Coricidin Meaning". Dictionary.com. March 12, 2018.
  3. ^ "Schering-Plough profile". adbrands.net. June 24, 2016.
  4. ^ "Coricidin HBP Cough and Cold", WebMD. Retrieved 7 January 2017.
  5. ^ Silva AR, Dinis-Oliveira RJ (May 2020). "Pharmacokinetics and pharmacodynamics of dextromethorphan: clinical and forensic aspects". Drug Metabolism Reviews. 52 (2): 258–282. doi:10.1080/03602532.2020.1758712. PMID 32393072.
  6. ^ "Duane Allman's Coricidin Bottle Slide Returns Back to Allman Family After 40 Years". Jambands. May 22, 2013.
  7. ^ Furlong P (February 17, 2014). "Gregg and Duane Were Brothers". kuvo.org. KUVO. It was his birthday (and he had a cold), so I went and bought him a bottle of Coricidin. . . Then I went by the record store and got that first Taj Mahal record, with all the butterflies on the cover and him sitting on a rocking chair. We'd played with Taj before, borrowed an amplifier from him. So I got Duane that record and the pills." Gregg took the gifts over to Duane's and left them on his front porch. Twenty-four hours later, Duane called, "Get over here quick, babybrah (for baby brother). Quick, man!" Duane had taken the pills out of the bottle and removed the label. "He put on that Taj Mahal record, with Jesse Ed Davis playing slide on 'Statesboro Blues,' and started playing along with it. When I left those pills by his door, he hadn't known how to play slide. From the moment that Duane put that Coricidin bottle on his ring finger, he was a natural.
  8. ^ "The Allman Brothers Band". Guitar Techniques. August 7, 2015 – via PressReader.
  9. ^
[edit]
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