Talk:Myelin basic protein: Difference between revisions
The protein structure is wrong |
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{{WikiProject Molecular Biology|MCB=yes|MCB-importance=low}} |
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==Wiki Education Foundation-supported course assignment== |
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[[File:Sciences humaines.svg|40px]] This article was the subject of a Wiki Education Foundation-supported course assignment, between <span class="mw-formatted-date" title="2020-09-01">1 September 2020</span> and <span class="mw-formatted-date" title="2020-12-17">17 December 2020</span>. Further details are available [[Wikipedia:Wiki_Ed/Brigham_Young_University/BYU-Biophysics_PDBio_568_(Fall)|on the course page]]. Student editor(s): [[User:Vazi97|Vazi97]]. Peer reviewers: [[User:ExasperatedOctopus|ExasperatedOctopus]], [[User:Snowwhite5567|Snowwhite5567]]. |
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{{small|Above undated message substituted from [[Template:Dashboard.wikiedu.org assignment]] by [[User:PrimeBOT|PrimeBOT]] ([[User talk:PrimeBOT|talk]]) 04:43, 17 January 2022 (UTC)}} |
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== Structure section == |
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Hey all, I have added a section on structure that discusses the intrinsic disorder of MBP as well as its post-translational modifications. I included several new citations, and especially relied on work by Boggs and Harauz. There is a lot of info I was working to sift through, so feel free to clarify or adjust as needed. I also included a figure I created showing the relationship between degree of citrullination of net positive charge of the protein.[[User:Vazi97|Vazi97]] ([[User talk:Vazi97|talk]]) 19:18, 13 December 2020 (UTC) |
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== Function section == |
== Function section == |
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Seems curing disease is as fast as hand-pipetting will allow. Someone needs to automate this. <small><span class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[User:Shtanto|Shtanto]] ([[User talk:Shtanto|talk]] • [[Special:Contributions/Shtanto|contribs]]) 14:23, 22 March 2012 (UTC)</span></small><!-- Template:Unsigned --> <!--Autosigned by SineBot--> |
Seems curing disease is as fast as hand-pipetting will allow. Someone needs to automate this. <small><span class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[User:Shtanto|Shtanto]] ([[User talk:Shtanto|talk]] • [[Special:Contributions/Shtanto|contribs]]) 14:23, 22 March 2012 (UTC)</span></small><!-- Template:Unsigned --> <!--Autosigned by SineBot--> |
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If i am not mistaken, the protein crystal structure is wrong. The picture actually shows [[HLA-DR2]] receptor. The referenced PDB file(1BX2) has only a few fragments of MBP (chains C and F) that bind to the alpha helices on the right of the picture. See: http://www.rcsb.org/pdb/explore/explore.do?structureId=1BX2 |
If i am not mistaken, the protein crystal structure is wrong. The picture actually shows [[HLA-DR2]] receptor. The referenced PDB file(1BX2) has only a few fragments of MBP (chains C and F) that bind to the alpha helices on the right of the picture. See: http://www.rcsb.org/pdb/explore/explore.do?structureId=1BX2 <span style="font-size: smaller;" class="autosigned">— Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/181.167.174.197|181.167.174.197]] ([[User talk:181.167.174.197|talk]]) 20:39, 3 May 2014 (UTC)</span><!-- Template:Unsigned IP --> <!--Autosigned by SineBot--> |
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I don't know if should put this here, but I wanted to know the function of this protein, but under "Function" it doesn't really talk about the function of the protein, but it explains how it is transcribed. I would like to know the function of the protein, and what it really does in myelinsheets. [[User:Lubberink|Lubberink]] ([[User talk:Lubberink|talk]]) 15:18, 22 June 2014 (UTC) |
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==Gene Variations== |
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Are there any variants for the gene for myelin?[[User:Flaviusvulso|Flaviusvulso]] ([[User talk:Flaviusvulso|talk]]) 02:18, 21 March 2019 (UTC) |
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== believed == |
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The lead states {{xt|Myelin basic protein (MBP) is a protein <b>believed</b> to be important in the process...}} I have added an {{tl|weasel inline}} ahead of the '{{xt|believed}}' because it doesn't provide any information who believes it, or what type of believing (hypothesis, etc.) it is, as this could be clearly stated for clarity. [[User:ExclusiveEditor|<span style="background:Orange;color:White;padding:2px;">Exclusive</span><span style="background:black; color:White; padding:2px;">Editor</span>]] [[User talk:ExclusiveEditor|<sub>Notify Me!</sub>]] 18:36, 9 December 2024 (UTC) |
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Latest revision as of 18:36, 9 December 2024
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Wiki Education Foundation-supported course assignment
[edit]
This article was the subject of a Wiki Education Foundation-supported course assignment, between 1 September 2020 and 17 December 2020. Further details are available on the course page. Student editor(s): Vazi97. Peer reviewers: ExasperatedOctopus, Snowwhite5567.
Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 04:43, 17 January 2022 (UTC)
Structure section
[edit]Hey all, I have added a section on structure that discusses the intrinsic disorder of MBP as well as its post-translational modifications. I included several new citations, and especially relied on work by Boggs and Harauz. There is a lot of info I was working to sift through, so feel free to clarify or adjust as needed. I also included a figure I created showing the relationship between degree of citrullination of net positive charge of the protein.Vazi97 (talk) 19:18, 13 December 2020 (UTC)
Function section
[edit]Is copy & paste the way things are usually done? Not entirely identical, but close. http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=DetailsSearch&Term=4155
Seems curing disease is as fast as hand-pipetting will allow. Someone needs to automate this. — Preceding unsigned comment added by Shtanto (talk • contribs) 14:23, 22 March 2012 (UTC)
If i am not mistaken, the protein crystal structure is wrong. The picture actually shows HLA-DR2 receptor. The referenced PDB file(1BX2) has only a few fragments of MBP (chains C and F) that bind to the alpha helices on the right of the picture. See: http://www.rcsb.org/pdb/explore/explore.do?structureId=1BX2 — Preceding unsigned comment added by 181.167.174.197 (talk) 20:39, 3 May 2014 (UTC)
I don't know if should put this here, but I wanted to know the function of this protein, but under "Function" it doesn't really talk about the function of the protein, but it explains how it is transcribed. I would like to know the function of the protein, and what it really does in myelinsheets. Lubberink (talk) 15:18, 22 June 2014 (UTC)
Gene Variations
[edit]Are there any variants for the gene for myelin?Flaviusvulso (talk) 02:18, 21 March 2019 (UTC)
believed
[edit]The lead states Myelin basic protein (MBP) is a protein believed to be important in the process... I have added an {{weasel inline}} ahead of the 'believed' because it doesn't provide any information who believes it, or what type of believing (hypothesis, etc.) it is, as this could be clearly stated for clarity. ExclusiveEditor Notify Me! 18:36, 9 December 2024 (UTC)