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{{Short description|Public medical school in Worcester, Massachusetts, US}}
{{Infobox_University
{{use mdy dates|date=October 2019}}
|name = University of Massachusetts<br/>Medical School

|image = [[Image:UMMS_Logo.gif |UMMS Logo]]
{{primary sources|date=August 2022}}{{Infobox university
|established = 1962
| name = University of Massachusetts<br />Chan Medical School
|type = Public
| image = [[Image:UMMS Chan Logo.svg|214px|center|UMMS Logo]]
|chancellor = Aaron Lazare
| established = 1962
|enrollment = School of Medicine<br/>412 (2005-2006)<br/><br/>Graduate School of Biomedical Sciences<br/>382(2005-2006)<br/><br/>Graduate School of Nursing<br/>214 (2005-2006)
| type = [[Public university|Public]] [[medical school]]
|faculty = Full-time 934<br/> Part-time 120
|city = Worcester
| parent = [[University of Massachusetts]]
|state = Massachusetts
| president = [[Marty Meehan]]|
|country = United States
| chancellor = Michael Collins
| endowment = $207.5 million (2018)<ref>{{cite web|title=2018 REPORT ON ANNUAL INDICATORS University Performance Measurement System July 2018|publisher=[[University of Massachusetts]]|url=https://www.umassp.edu/sites/umassp.edu/files/publications/2018%20PMS%20Annual%20Indicators%20Report.pdf|access-date=June 12, 2019|archive-date=July 1, 2019|archive-url=https://web.archive.org/web/20190701194546/https://www.umassp.edu/sites/umassp.edu/files/publications/2018%20PMS%20Annual%20Indicators%20Report.pdf|url-status=live}}</ref>
|campus = Urban
| enrollment = Medicine: 608<br/>Biomedical Sciences: 306<br/> Nursing: 192<br/> MD/PhD: 78<br>(2019)
|colors = Blue, White & Black
| city = [[Worcester, Massachusetts|Worcester]]
|Web Site= [http://www.umassmed.edu]
| state = [[Massachusetts]]
}}<p>The '''University of Massachusetts Medical School (UMMS)''' is one of five campuses of the [[University of Massachusetts|University of Massachusetts (UMass)]] system and is home to three schools: the [[#School of Medicine]], the [[#Graduate School of Biomedical Sciences]], the [[#Graduate School of Nursing]]; a thriving [[#biomedical research enterprise]]; and a range of [[#public service initiatives]] throughout the state. One of the fastest-growing academic health centers in the country, UMMS is located in Worcester, Mass., while the other UMass sites are located in [[University of Massachusetts Amherst|Amherst]], [[University of Massachusetts Boston|Boston]], [[University of Massachusetts Dartmouth|Dartmouth]] and [[University of Massachusetts Lowell|Lowell]]. UMMS can alternately be referred to as UMass Worcester. </p>
| country = United States
<p>UMMS is ranked fourth in primary care education among the nation’s 125 medical schools in the 2006 [[U.S. News & World Report|''U.S.News & World Report'']] annual guide, “America’s Best Graduate Schools.” UMMS is also a major center for research. In the past four decades, UMMS researchers have made pivotal advances in a broad range of disease families, from HIV and infectious diseases, to cancer and genetic disorders, to diabetes and immune disease. UMMS [[#faculty]] discovered the link between the immune system and type 1 diabetes, developed cancer detection technology, found the genetic cause that underlies the third most common form of the muscular dystrophies, established the fundamental difference between HIV and other retroviruses and co-discovered RNA interference (RNAi), a naturally occurring gene-silencing process that has become a vital tool in research focused on such areas as diabetes, HIV/AIDS and cancer. Currently, UMMS scientists are making strides in collaborative efforts to develop vaccines for the avian flu, HIV and West Nile virus.</p>
| coor = {{coord|42.276815|-71.762445|display=inline,title}}
<br/>
| campus = Urban
| colors = Blue, white and black {{color box|#0F2382}}{{color box|white}}{{color box|black}}
| website = {{URL|https://umassmed.edu}}
| accreditation = [[New England Commission of Higher Education|NECHE]]
}}

The '''UMass Chan Medical School''' is a [[Public university|public]] [[medical school]] in [[Worcester, Massachusetts]]. It is part of the [[University of Massachusetts]] system. It consists of three schools: the T.H. Chan School of Medicine, the Morningside Graduate School of Biomedical Sciences, and the Tan Chingfen Graduate School of Nursing. The school also operates a biomedical research enterprise and a range of public-service initiatives throughout the state.<ref>{{Cite web |date=2019-03-25 |title=University of Massachusetts |url=https://www.timeshighereducation.com/world-university-rankings/university-massachusetts |url-status=live |archive-url=https://web.archive.org/web/20230215203126/https://www.timeshighereducation.com/world-university-rankings/university-massachusetts |archive-date=February 15, 2023 |access-date=2019-06-12 |website=Times Higher Education (THE) |language=en}}</ref><ref>{{cite web |title=University of Massachusetts announces $175 Million transformational gift to its Medical School |url=https://www.umassmed.edu/umasschan/ |website=UMass Chan |date=September 5, 2013 |publisher=UMass Chan Medical School |access-date=7 September 2021 |archive-date=September 7, 2021 |archive-url=https://web.archive.org/web/20210907170220/https://www.umassmed.edu/umasschan/ |url-status=live }}</ref>

==History==
==History==
The University of Massachusetts Medical School (UMMS) was established by the [[1961–1962 Massachusetts legislature|162nd Massachusetts General Court]] in 1962 to provide residents of the commonwealth an opportunity to study medicine at an affordable cost and to increase the number of primary-care physicians practicing in the commonwealth's under-served areas.<ref>{{cite book|last=Feldberg|first=Michael|title=UMass Boston at 50: A Fiftieth-Anniversary History of the University of Massachusetts Boston|publisher=[[University of Massachusetts Press]]|place=[[Amherst, Massachusetts]]|year=2015|page=5|isbn=978-1625341693}}</ref> The legislation was signed into law by [[Governor of Massachusetts|Massachusetts Governor]] [[John A. Volpe|John Volpe]].<ref>{{cite book|last=More|first=Ellen S.|year=2012|title=The University of Massachusetts Medical School, A History: Integrating Primary Care and Biomedical Research|place=Worcester, MA|publisher=University of Massachusetts Medical School|page=16|doi=10.13028/e2m6-hs02}}</ref> The School of Medicine accepted its first class of 16 students in 1970. Six years later a 371-bed hospital opened on campus; the Graduate School of Biomedical Sciences opened in 1979, and the Graduate School of Nursing opened in 1986.
<p>UMMS was established by an act of the Massachusetts Legislature in l962 to provide residents of the Commonwealth an opportunity to study medicine at an affordable cost and to increase the number of primary care physicians practicing in the Commonwealth’s underserved areas.</p>

<p>The [[#School of Medicine]] accepted its first class of 16 students in 1970. Six years later, a 371-bed hospital opened on campus, and today, the UMMS campus is home to three schools: the [[#School of Medicine]], the [[#Graduate School of Biomedical Sciences]], opened in 1979, and the [[#Graduate School of Nursing]], opened in 1986. </p>
In 1998 the UMMS system of hospitals and clinics merged with Memorial Health Care to form [[UMass Memorial Health Care]], the largest health-care provider in [[Central Massachusetts]] and clinical partner of UMMS.<ref>{{Cite web|url=https://www.umassmed.edu/about/clinical/|title=UMass Memorial Health Care - our Clinical Partner at UMMS|date=2014-02-22|website=University of Massachusetts Medical School|language=en|access-date=2019-06-12|archive-date=July 5, 2019|archive-url=https://web.archive.org/web/20190705043349/https://www.umassmed.edu/about/clinical/|url-status=live}}</ref>
<p>The research mission at UMMS evolved in 1997 with the merger of UMMS and the Worcester Foundation for Biomedical Research, the Shrewsbury, Mass. institution where researchers developed the birth control pill in the early 1960s. By retaining its own board of trustees under the umbrella of UMMS, the Foundation continues to function as a nonprofit philanthropic organization that supports the research enterprise. </p>

<p>In 1998, the UMMS system of hospitals and clinics merged with Memorial Health Care to form UMass Memorial Health Care, the largest health care provider in Central Massachusetts and the clinical partner of UMMS.</p>
===Name change===
<table><tr><td>
In 2021 an unrestricted $175 million gift from the family of Hong Kong real estate developer [[T.H. Chan|Chan Tseng-hsi]] resulted in the name of the medical school, along with the biosciences and nursing schools, to be changed.<ref>{{Cite web|url=https://www.massachusetts.edu/news/university-massachusetts-announces-175-million-transformational-gift-its-medical-school|title=University of Massachusetts announces $175 million transformational gift to its Medical School|website=UMass System|date=September 7, 2021 }}</ref>
===UMMS Chancellors and Deans of the School of Medicine===

</td></tr><tr></tr>
===Worcester Foundation for Biomedical Research===
<tr><td>
{{main|Worcester Foundation for Biomedical Research}}
<div id="Lamar Soutter"></div>
The research mission at UMMS was augmented in 1997 with the acquisition of the financially ailing Worcester Foundation for Biomedical Research, the [[Shrewsbury, Massachusetts]] institution where researchers developed the [[combined oral contraceptive pill]] during the early 1960s.
Lamar Soutter, MD

</td></tr>
<tr><td>Dean of UMass Medical School</td><td></td><td></td><td></td><td>Feb. 24, 1964 – April 5, 1975</td></tr>
<tr><td>Chancellor of UMass – Worcester</td><td></td><td></td><td></td><td>Feb. 6, 1974 – April 5, 1975
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>R. W. Butcher, PhD</td></tr>
<tr><td>Acting Dean</td><td></td><td></td><td></td><td>Feb. 21, 1975 – Jan. 28, 1976
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>Roger J. Bulger, MD</td></tr>
<tr><td>Chancellor/Dean</td><td></td><td></td><td></td><td>Jan. 29, 1976 – Nov. 30, 1978
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>H. Maurice Goodman, PhD</td></tr>
<tr><td>Acting Chancellor/Dean</td><td></td><td></td><td></td><td>Nov. 15, 1978 – June 30, 1979
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>Robert E. Tranquada, MD</td></tr>
<tr><td>Chancellor</td><td></td><td></td><td></td><td>July 1, 1979 – Aug. 31, 1986</td></tr>
<tr><td>Dean</td><td></td><td></td><td></td><td>July 1, 1979 – June 4, 1986
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>James E. Dalen, MD</td></tr>
<tr><td>Acting Chancellor</td><td></td><td></td><td></td><td>Aug. 15, 1986 – Aug. 31, 1987
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>James B. Hanshaw, MD</td></tr>
<tr><td>Dean/Provost</td><td></td><td></td><td></td><td>June 4, 1986 – Sept. 30, 1989</td></tr>
<tr><td>Acting Chancellor</td><td></td><td></td><td></td><td>Sept. 1, 1987 – Oct. 31, 1987
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>Leonard Laster, MD</td></tr>
<tr><td>Chancellor</td><td></td><td></td><td></td><td>Nov. 1, 1987 – Aug. 31, 1990
</td></tr>
<tr></tr>
<tr></tr>
<tr><td>
<div id="current chancellor"></div>
Aaron Lazare, MD
</td></tr>
<tr><td>Dean ''ad interim"</td><td></td><td></td><td></td><td>Oct. 1, 1989</td></tr>
<tr><td>Chancellor ''ad interim''</td><td></td><td></td><td></td><td>Sept. 4, 1990</td></tr>
<tr><td>Dean</td><td></td><td></td><td></td><td>July 25, 1990</td></tr>
<tr><td>Chancellor/Dean</td><td></td><td></td><td></td><td>May 15, 1991 – present</td></tr>
<tr></tr>
<tr><td>
===Deans of the Program in Biomedical Sciences===
</td></tr>
<tr></tr>
<tr><td>George E. Wright, PhD</td></tr>
<tr><td>Acting Dean</td><td></td><td></td><td></td><td>Fall 1979 – June 1980</td></tr>
<tr><td>Dean</td><td></td><td></td><td></td><td>June 1981 – June 1984
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>Trudy G. Morrison, PhD</td></tr>
<tr><td>Acting Dean</td><td></td><td></td><td></td><td>June 1980 – June 1981
</td></tr>
<tr></tr>
<tr><td>
===Deans of the Graduate School of Biomedical Sciences===
</td></tr>
<tr></tr>
<tr><td>Thomas B. Miller Jr., PhD</td></tr>
<tr><td>Dean</td><td></td><td></td><td></td><td>June 1984 – June 2002
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>Anthony Carruthers, PhD</td></tr>
<tr><td>Dean</td><td></td><td></td><td></td><td>December 2002 – present
</td></tr>
<tr></tr>
<tr><td>
===Deans of the Graduate School of Nursing===
</td></tr>
<tr></tr>
<tr><td>Kathleen M. Dirschel, RN, PhD</td></tr>
<tr><td>Dean</td><td></td><td></td><td></td><td>June 1985
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>Lillian R. Goodman, EdD</td></tr>
<tr><td>Dean</td><td></td><td></td><td></td><td>September 1991 – November 1999
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>Doreen Harper, PhD, CS, ANP, FAAN</td></tr>
<tr><td>Dean</td><td></td><td></td><td></td><td>July 1, 2000 – Nov. 1, 2005
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
<tr><td>Paulette Seymour Route, PhD</td></tr>
<tr><td>Interim Dean</td><td></td><td></td><td></td><td>Nov. 1, 2005 – present
</td></tr>
<tr></tr>
<tr></tr>
<tr></tr>
</table>
<div id="education"></div>
==Academics==
==Academics==

<p></p>
<div id="School of Medicine"></div>
===School of Medicine===
===School of Medicine===
<p>Since accepting its first class in 1970, the School of Medicine has provided Massachusetts students with an education of the highest quality. Approximately 100 students enroll annually, and more than 2,700 students have received medical degrees from UMMS. The School of Medicine has garnered a national reputation for its primary care program and consistently ranks in the top ten percent in the annual [[U.S. News & World Report|''U.S.News & World Report'']] guide, “America’s Best Graduate Schools.” Well more than half of each graduating class enters into primary care residencies, a trend that underscores the school’s founding mission. In addition, a high number of graduates practice throughout the state.</p>
Accredited by the [[Liaison Committee on Medical Education]], the T.H. Chan School of Medicine grants the [[Doctor of Medicine|MD]] degree to its graduates. With the exception of MD/PhD students, degree candidates were formerly required to be Massachusetts residents, a policy which has changed beginning with the entering class of 2016. Approximately 165 students enroll annually, and more than 4,350 students have received medical degrees from UMMS. The School of Medicine has gained a national reputation for its primary-care program and consistently ranks in the top 10 percent of schools in the annual ''[[U.S. News & World Report]]'' guide, "America’s Best Graduate Schools". [[SCImago Journal Rank]] listed the university at No. 74 in the US and No. 248 globally.<ref>{{cite web|url=https://www.scimagoir.com/rankings.php?sector=Higher+educ.&country=USA|title=Scimago Institutions Rankings|website=www.scimagoir.com|access-date=May 27, 2019|archive-date=July 2, 2019|archive-url=https://web.archive.org/web/20190702141707/https://www.scimagoir.com/rankings.php?sector=Higher+educ.&country=USA|url-status=live}}</ref> Over half of each graduating class enters primary-care residencies, a trend underscoring the school's founding mission, though that figure has decreased in recent years. In addition, a high number of graduates practice throughout the state. UMass Medical is also [[Higher education accreditation in the United States|accredited]] by the [[New England Commission of Higher Education]].<ref>{{Citation|title=Massachusetts Institutions – NECHE|publisher=[[New England Commission of Higher Education]]|url=https://www.neche.org/institutions/ma/|access-date=May 26, 2021|archive-date=October 9, 2021|archive-url=https://web.archive.org/web/20211009082139/https://www.neche.org/institutions/ma/|url-status=live}}</ref>

<p>Through educational planning, development, innovation and resources, students learn the core knowledge, skills, attitudes and values that serve as the foundation for physician training at UMMS. The institution attributes its success in training primary care physicians in part to a curriculum that emphasizes early exposure to community practice, beginning in the first year of medical school. Third-year students are required to complete an innovative clerkship rotation program in which they spend six weeks at a time with community-based physicians. The curriculum’s learning objectives are targeted at developing the foundational competencies required of all physicians today, including competency in communication, scientific, and patient and community advocacy skills.</p>
{{Infobox US university ranking
<p>Reflective of the success of these learning objectives are the results of the annual Match Day at UMMS, when students discover where they will begin their careers as doctors. In 2006, National Resident Matching Program results showed that members of the UMMS class were accepted into some of the most competitive residency programs in the country, with 68 percent of graduates entering primary care including obstetrics & gynecology and pediatrics.</p>
| USNWR_W = 251<ref>{{cite web|url=https://www.usnews.com/education/best-global-universities/university-of-massachusetts-worcester-166708|title=Rankings|website=U.S. News & World Report|access-date=2019-05-27|archive-date=March 9, 2018|archive-url=https://web.archive.org/web/20180309221109/https://www.usnews.com/education/best-global-universities/university-of-massachusetts-worcester-166708|url-status=live}}</ref>
<div id="Graduate School of Biomedical Sciences"></div>
| ARWU_W = 151–200<ref name="shanghairanking.com">{{cite web |url=http://www.shanghairanking.com/ARWU2016.html |title=ARWU World University Rankings 2016 &#124; Academic Ranking of World Universities 2016 &#124; Top 500 universities &#124; Shanghai Ranking - 2016 |publisher=Shanghai Ranking |access-date=2019-05-27 |archive-date=June 1, 2020 |archive-url=https://web.archive.org/web/20200601014730/http://www.shanghairanking.com/ARWU2016.html |url-status=dead }}</ref>
}}

===Graduate School of Biomedical Sciences===
===Graduate School of Biomedical Sciences===
<p> A faculty-initiated PhD program, the Graduate School of Biomedical Sciences (GSBS) trains scientists in a specialty area with a broad background in the basic medical sciences in preparation for conducting research with direct relevance to human disease. The GSBS offers students a multidisciplinary program of study in which they have freedom of choice in curriculum and in the selection of mentors for their graduate thesis research—an approach that is matched by very few graduate programs in the nation.</p>
The Morningside Graduate School of Biomedical Sciences (GSBS) is a PhD-granting program that trains scientists in a specialty area with a broad background in the basic medical sciences in preparation for conducting research with direct relevance to human disease. According to the GSBS website, the school offers students a multidisciplinary program of study, in which they have freedom of choice in curriculum and in the selection of mentors for their graduate-thesis research.<ref>{{cite web|archive-url=https://web.archive.org/web/20120507075526/http://www.umassmed.edu/gsbs/index.aspx|title=Graduate School of Biomedical Sciences|url=http://www.umassmed.edu/gsbs/|archive-date=2012-05-07|website=University of Massachusetts Medical School}}</ref> Since the first class of seven students enrolled in 1979, more than 1000 students have earned PhDs from the GSBS.

<p>Since the first class of seven students enrolled in 1979, more than 300 students have earned PhDs from the GSBS. The program, which continues to grow and evolve as new frontiers in science are discovered and explored, is gaining national and international recognition for excellence. In 2006, [[U.S. News & World Report|''U.S.News & World Report'']] ranked the GSBS 51st in the nation for excellence in PhD studies in Biomedical Sciences.</p>
<div id="Graduate School of Nursing"></div>
===Graduate School of Nursing===
===Graduate School of Nursing===
<p>Since the opening of the Graduate School of Nursing (GSN) in 1986, more than 600 students have obtained a nursing master’s, post-master’s or doctoral degree from the school. Through education, research, practice and service, the GSN prepares professional and advanced practice nurses, nurse scientists and educators as leaders in nursing and health care delivery to diverse populations. The theoretical foundations of nursing, research process and design, societal influences on nursing, advanced pathophysiology, pharmacology, health assessment and specialty content are the basis of study at the GSN. Advanced practice nurses receive professional education and training to become adult acute/critical care nurse practitioners, adult ambulatory/community care nurse practitioners and advanced practice nurse educators. The GSN also offers subspecialty professional education and training in selected areas.</p>
Since the opening of the Tan Chingfen Graduate School of Nursing (GSN) in 1986, more than 600 students have obtained a nursing master's, post-master's or doctoral degree from the school. The GSN prepares professional and [[advanced practice nurse]]s, nurse scientists and educators as leaders in nursing and health-care delivery to diverse populations through education, research, practice and service (according to the GSN website).<ref>{{cite web|website=University of Massachusetts Medical School|archive-url=https://web.archive.org/web/20120507072236/http://www.umassmed.edu/gsn/index.aspx|title=Graduate School of Nursing|url=http://www.umassmed.edu/gsn/|archive-date=2012-05-07}}</ref>

<div id="biomedical research enterprise"><div id="research"></div></div>
==Research==
==Research==
UMMS researchers have made advances in a broad range of disease families, from HIV and infectious diseases to cancer, genetic disorders, diabetes and immune disease.{{Citation needed|date=June 2019}} UMMS faculty discovered the link between the immune system and type-1 diabetes, found the genetic cause underlying the third-most-common form of the muscular dystrophies, and established the fundamental difference between HIV and other retroviruses.{{Citation needed|date=June 2019}}
<p>Beyond its core mission of distinction in health sciences education, UMMS over the past decade has exploded onto the national scene as a major center for research. In 1998, UMMS researcher Craig Mello, PhD, an investigator of the prestigious Howard Hughes Medical Institute, and his colleague Andrew Fire, PhD, then of the Carnegie Institution of Washington, discovered RNA interference (RNAi). Drs. Mello and Fire demonstrated that small pieces of double-stranded RNA had interfered with the expression of a gene whose coding sequence of DNA was similar to that of the RNA they tested. Since the discovery of RNAi, UMMS researchers have taken full advantage of its technology to speed investigation into a variety of diseases.</p>

<p>UMMS scientists also pioneered the fundamental elements of DNA-based flu vaccines in the 1990s. Today, UMMS Professor of Medicine Shan Lu, MD, PhD, leader of the UMMS DNA vaccine efforts, and his colleagues have partnered with PowerMed, a British immunotherapeutics company, to advance the development of a potential avian flu vaccine. Dr. Lu’s team has also been recognized for its work in the creation of an HIV vaccine, which, in Phase I testing, was found to generate antibody and T-cell responses in otherwise healthy people not infected with HIV.</p>
In the 1990s. UMMS Professor of Medicine Shan Lu, leader of the UMMS DNA-based flu vaccine efforts, worked to advance the development of a potential avian-flu vaccine.<ref>{{Cite web|url=https://www.umassmed.edu/news/news-archives/2011/10/shan-lu-to-lead-international-society-for-vaccines/|title=Shan Lu to lead International Society for Vaccines - UMass Medical School - Worcester|date=2013-12-15|website=University of Massachusetts Medical School|language=en|access-date=2019-06-12|archive-date=July 1, 2019|archive-url=https://web.archive.org/web/20190701161913/https://www.umassmed.edu/news/news-archives/2011/10/shan-lu-to-lead-international-society-for-vaccines/|url-status=live}}</ref> Lu's team has also been recognized for its work in the creation of an HIV vaccine,<ref name=":0">{{Cite web|url=https://www.umassmed.edu/news/news-archives/2016/06/umms-receives-$17.3-million-to-oversee-manufacturing-of-hiv-vaccine/|title=UMMS receives $17.3 million to oversee manufacturing of HIV vaccine|date=2016-06-22|website=University of Massachusetts Medical School|language=en|access-date=2019-06-12|archive-date=July 1, 2019|archive-url=https://web.archive.org/web/20190701192846/https://www.umassmed.edu/news/news-archives/2016/06/umms-receives-%2417.3-million-to-oversee-manufacturing-of-hiv-vaccine/|url-status=live}}</ref> which in Phase I testing was found to generate antibody and T-cell responses in otherwise healthy people not infected with HIV.<ref>{{Cite web|url=https://www.mdmag.com/medical-news/umass-researchers-move-into-phase-1-trial-with-hiv-vaccine|title=UMass Researchers Move Into Phase 1 Trial with HIV Vaccine|website=MD Magazine|access-date=2019-06-12}}</ref> In 1998, UMMS researcher [[Craig Mello]] (an investigator at the [[Howard Hughes Medical Institute]]) and his colleague [[Andrew Fire]] (of [[Stanford University]], then of the [[Carnegie Institution]] in Washington, D.C.) discovered [[RNA interference]] (RNAi). They demonstrated that small pieces of double-stranded RNA had interfered with the expression of a gene whose coding sequence of DNA was similar to that of the RNA they tested. Mello and Fire received the 2006 [[Nobel Prize in Physiology or Medicine]] for their discoveries related to RNA interference.<ref name=":1">{{Cite web|url=https://www.nobelprize.org/prizes/medicine/2006/summary/|title=The Nobel Prize in Physiology or Medicine 2006|website=NobelPrize.org|language=en-US|access-date=2019-06-12|archive-date=May 23, 2020|archive-url=https://web.archive.org/web/20200523072643/https://www.nobelprize.org/prizes/medicine/2006/summary/|url-status=live}}</ref>
<p>The institution’s strong commitment to its research mission is reflected in its ranking of second among 10 public medical schools in the Northeast in the amount of funds awarded by the National Institutes of Health. Federal and private research grants and contracts at UMMS rose from about $2 million in 1977 to more than $174 million in 2005, putting UMMS in the top third of all research medical schools, public or private. UMMS currently supports more than 260 investigators working on advancements in the treatment of disease and injury. </p>

<p>The UMMS portfolio of commercial ventures and intellectual property continues to reap great dividends for the institution and the [[University of Massachusetts]] system. Catapulted by the success of UMMS licenses and patents, including high profile intellectual property related to RNAi gene-silencing technology and drug and vaccine development, UMass was ranked 11th in the nation—a remarkable 1st in Massachusetts—in generating income from campus-based research and the development of new technology among universities reporting more than $10 million in income in the most recent national survey by the Association of University Technology Managers. Earnings rose from $19.8 million in fiscal year 2003 to $26.5 million in 2004, before reaching $28.7 million in 2005.</p>
Federal and private research grants and contracts at UMCMS rose from about $2&nbsp;million in 1977{{Citation needed|date=June 2019}} to more than $322 million in 2022<ref>{{Cite web |date= September 5, 2013|title=About UMass Chan Medical School |url=https://www.umassmed.edu/about/ |archive-url= |archive-date= |access-date= |website=University of Massachusetts Medical School |language=en}}</ref> an increase of over 16,000% over forty-five years.
===Massachusetts Biologic Laboratories===

<p>The Massachusetts Biologic Laboratories (MBL) is the only publicly owned, non-profit FDA-licensed manufacturer of vaccines and other biologic products in the United States. Established in 1894 by the state Board of Health to produce diphtheria antitoxin, the operations of the MBL were transferred from the state Department of Public Health to UMMS in 1997 in order to maintain the MBL’s singular focus on improving public health through applied research, development and production of biologic products.</p>
===MassBiologics===
<p>Over the years, the MBL has introduced into general use vaccines to prevent pertussis, tetanus, diphtheria, and other diseases. The lab’s scientists have also pioneered plasma products to protect infants and toddlers from serious infectious diseases. In recent years, the MBL has been called upon to respond to the threat of such emerging public health issues as SARS, avian flu and rabies. During the past two decades, the MBL has also been an active participant in the national effort to develop and produce “orphan products,” which are those drugs intended for limited populations (less than 200,000 patients per year). Many of these are critical, life-saving products for those affected by a rare disease. Despite their importance, commercial manufacturers are often reluctant to invest the resources required to bring these products to market. The MBL, however, has developed or collaborated on five such products in the past 20 years. To continue such efforts, in 2005 the MBL opened a new $80 million filling facility that will allow the laboratories to continue to fill its own products as well as offer this limited resource for both private and public needs.</p>
MassBiologics is the only publicly owned, non-profit FDA-licensed<ref>{{cite web|website=U.S. Food and Drug Administration|title=Alphabetical List of Establishments Licensed to produce Biologics including Product Approval Dates|url=https://www.fda.gov/downloads/BiologicsBloodVaccines/UCM149969.pdf|access-date=December 16, 2019|archive-date=April 23, 2019|archive-url=https://web.archive.org/web/20190423064658/https://www.fda.gov/downloads/BiologicsBloodVaccines/UCM149969.pdf|url-status=live}}</ref> manufacturer of vaccine<ref>{{cite web|website=U.S. Food and Drug Administration|title=Approved Products, Tetanus & Diphtheria Toxoids, Adsorbed, Manufacturer: MassBiologics, License #1779|url=https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm164123.htm|access-date=December 16, 2019|archive-date=April 23, 2019|archive-url=https://web.archive.org/web/20190423064210/https://www.fda.gov/BiologicsBloodVaccines/Vaccines/ApprovedProducts/ucm164123.htm|url-status=live}}</ref> and other [[Biopharmaceutical|biologic]] products in the United States. First established in 1894, the University of Massachusetts Biologic Laboratory was re-established in 1997 by the Massachusetts legislature,<ref>{{cite web|title=Massachusetts General Law: Chapter 75, Section 43|url=http://www.malegislature.gov/Laws/GeneralLaws/PartI/TitleXII/Chapter75/Section43|website=www.malegislature.gov|access-date=September 2, 2011|archive-date=September 30, 2022|archive-url=https://web.archive.org/web/20220930165854/https://www.malegislature.gov/Laws/GeneralLaws/PartI/TitleXII/Chapter75/Section43|url-status=live}}</ref> and oversight was transferred from the Department of Public Health to UMMS.<ref>{{Cite web|url=https://www.umassmed.edu/massbiologics/about/|title=About - MassBiologics {{!}} UMass Medical School - Worcester|date=2013-11-02|website=University of Massachusetts Medical School|language=en|access-date=2019-06-12|archive-date=May 27, 2019|archive-url=https://web.archive.org/web/20190527182142/https://umassmed.edu/massbiologics/about/|url-status=live}}</ref>
<div id="public service initiatives"><div id="public service mission"></div></div>

==Public Service==
In recent years, MassBiologics has been called upon to respond to the threat of SARS, avian flu, and rabies. MassBiologics has developed or collaborated on five “orphan products” over the past twenty years. {{Citation needed|date=June 2019}} MassBiologics continues to market its FDA-licensed Td (tetanus and diphtheria) vaccine, providing a substantial proportion of the U.S. requirement for this vaccine.{{Citation needed|date=June 2019}} MassBiologics participates in the discovery, production and clinical testing of monoclonal antibodies (including antibodies to [[Clostridioides difficile (bacteria)|Clostridioides difficile]]),<ref>{{cite journal|journal=New England Journal of Medicine|date=2010-01-21|volume=362|issue=3|pages=197–205|title=Treatment with monoclonal antibodies against Clostridium difficile toxins|doi=10.1056/NEJMoa0907635|last=Lowy|first=Israel|pmid=20089970|display-authors=et al|doi-access=free|url=https://repository.escholarship.umassmed.edu/bitstream/20.500.14038/43485/2/nejmoa0907635.pdf}}</ref> antibodies now known as [[actoxumab]] and [[bezlotoxumab]] In 2005, the firm opened an $80 million facility for monoclonal-antibody production. Co-developed with [[Serum Institute of India]], it invented a fast-acting anti-Rabies drug called Rabies Human Monoclonal Antibody (RMAb).<ref>{{cite news|url=http://timesofindia.indiatimes.com/city/pune/Fast-acting-anti-rabies-drug-set-for-India-launch/articleshow/51114312.cms|title=Fast-acting anti-rabies drug set for India launch|website=The Times of India|date=February 24, 2016 |access-date=2016-06-12|archive-date=January 1, 2021|archive-url=https://web.archive.org/web/20210101153718/https://timesofindia.indiatimes.com/city/pune/Fast-acting-anti-rabies-drug-set-for-India-launch/articleshow/51114312.cms|url-status=live}}</ref>
<p>UMMS is extending its mission of public service through its innovative Commonwealth Medicine initiative. Commonwealth Medicine provides partnership opportunities for dozens of state and local agencies to increase the value and quality of publicly funded health expenditures and to improve access and delivery of care to at-risk and uninsured populations. Through Commonwealth Medicine, public agencies can leverage the academic, research, management and clinical resources of UMMS to optimize efficiency and effectiveness.</p>

<div id="faculty"></div>
UMMS is extending its mission of public service through its Commonwealth Medicine initiative.<ref>{{cite web|url=http://www.umassmed.edu/commed/|title=Commonwealth Medicine|access-date=2012-05-23|website=University of Massachusetts Medicine School|archive-date=July 17, 2006|archive-url=https://web.archive.org/web/20060717172251/http://www.umassmed.edu/commed/|url-status=live}}</ref>

==Faculty==
==Faculty==
Notable faculty members include:
<p>UMMS faculty members are nationally recognized authorities on AIDS, cancer, diabetes, infectious diseases, pain control, arteriosclerosis, thyroid function, hypertension, joint replacement, organ transplantation, minimally invasive surgery, arthritis, senility and depression, among other areas. Distinguished faculty members include:</p>
* [[Victor Ambros]], [[Nobel Prize]] laureate for the discovery of [[microRNA]]. <ref>{{cite web|url=https://www.nobelprize.org/prizes/medicine/2024/summary/|title=The Nobel Prize in Physiology or Medicine 2024|website=www.nobelprize.org}}</ref>
*'''Craig C. Mello, PhD''', Howard Hughes Medical Institute Investigator and the Blais University Chair in Molecular Medicine: Co-discoverer of RNA Interference, recipient of the National Academy of Sciences Award in Molecular Biology, the Lewis S. Rosenstiel Award for Distinguished Work in Basic Medical Research, the Wiley Prize in the Biomedical Sciences, the Gairdner International Award, the Paul Ehrlich and Ludwig Darmstaedter Prize, the Warren Triennial Prize and the Massry Prize;
* Job Dekker, developer of the [[chromosome conformation capture]] method.
*'''Aldo Rossini, MD''', the William and Doris Krupp Professor of Medicine and director of the Division of Diabetes at UMMS: 2003 recipient of the American Diabetes Association Banting Medal for Scientific Achievement; and
* [[Katherine A. Fitzgerald]], molecular biologist and virologist, finalist for the 2011 [[Vilcek Prize]]<ref>{{cite web|url=https://www.vilcek.org/prizes/prize-recipients/2011/finalists.html|title=The Vilcek Foundation - Finalists|website=www.vilcek.org|access-date=May 27, 2019|archive-date=May 27, 2019|archive-url=https://web.archive.org/web/20190527182109/https://www.vilcek.org/prizes/prize-recipients/2011/finalists.html|url-status=live}}</ref>
*'''Michael Czech, PhD''', chair of the Program in Molecular Medicine: American Diabetes Association Banting Medal for Scientific Achievement (2001).
* [[Craig C. Mello]], [[Nobel Prize]] laureate for the discovery of [[RNA interference]].<ref>{{cite web |url=http://www.umassmed.edu/Content.aspx?id=43102 |title=UMass Medical School - Worcester |access-date=2014-08-13 |archive-url=https://web.archive.org/web/20140818165421/http://www.umassmed.edu/Content.aspx?id=43102 |archive-date=2014-08-18 |url-status=unfit }}</ref>
==Teaching Affiliates==
* [[Phillip D. Zamore]], biochemist of small RNAs.
<p>As a complement to its [[#education]], [[#research]]; and [[#public service mission]], the hospital and clinical components of UMMS are part of UMass Memorial Health Care. UMass Memorial is a $1.2 billion health care delivery system with acute care hospitals, ambulatory clinics and a network of primary care physicians and specialists throughout Central Massachusetts.</p>

=={{anchor|Teaching Affiliates and Clinical Partners}}Affiliates and clinical partners==
{{Main|UMass Memorial Health Care}}
The hospital and clinical components of UMMS are part of UMass Memorial Health Care (UMMHC). UMass Memorial is a multibillion-dollar health-care system consisting of acute-care hospitals, ambulatory clinics and a network of [[primary care]] physicians and specialists throughout [[central Massachusetts]].<ref name="umassmemorial.org">{{cite web|url=https://www.umassmemorialhealthcare.org/?id=18id%3D18|title=UMass Memorial Health Care|website=www.umassmemorialhealthcare.org|access-date=May 27, 2019|archive-date=July 2, 2019|archive-url=https://web.archive.org/web/20190702025921/https://www.umassmemorialhealthcare.org/?id=18id%3D18|url-status=live}}</ref> With approximately 13,000 employees (including 1,500 physicians), UMMHC is the largest health-care provider in central Massachusetts.<ref name="umassmemorial.org"/> Its flagship hospital (UMass Memorial Medical Center) straddles two campuses along [[Route 9 (Massachusetts)|Route 9]] in [[Worcester, Massachusetts]] and is designated by the [[American College of Surgeons]] as a [[Level I Trauma Center]].<ref name="umassmemorial.org"/>

Its largest publicly funded affiliate in the field of [[cancer]] research is the [[Quality Assurance Review Center]] (QARC), located in [[Lincoln, Rhode Island]]. Supported by the [[National Cancer Institute]] (NCI) and the [[National Institutes of Health]] (NIH), QARC receives radiotherapy data from around 1,000 hospitals in the United States.<ref>{{Cite web|url=https://www.qarc.org/|title=IROC Rhode Island|website=QARC|access-date=2019-06-12|archive-date=June 8, 2019|archive-url=https://web.archive.org/web/20190608084716/http://www.qarc.org/|url-status=live}}</ref>

UMMHC also maintains three community hospitals:<ref name="umassmemorial.org" />

*Clinton Hospital in [[Clinton, Massachusetts|Clinton]]
*HealthAlliance Hospital in [[Fitchburg, Massachusetts|Fitchburg]] and [[Leominster, Massachusetts|Leominster]]
*Marlborough Hospital in [[Marlborough, Massachusetts|Marlborough]]

==Campus==
==Campus==
[[File:Albert Sherman Center.jpg|alt=Angular, gray-and-white multi-story building|thumb|Albert Sherman Center]]
<p></p>

===Albert Sherman Center===
The Albert Sherman Center, a 512,000 square foot biomedical research and education facility, was unveiled to the public on January 30, 2013, in a ribbon-cutting ceremony attended by Gov. [[Deval Patrick]].<ref>{{Cite web|url=https://www.umassmed.edu/news/news-archives/2013/01/full-video-of-asc-opening-ceremony/|title=Full video of the Albert Sherman Center opening ceremony - UMass Medical School - Worcester|date=2013-12-22|website=University of Massachusetts Medical School|language=en|access-date=2019-06-12|archive-date=July 1, 2019|archive-url=https://web.archive.org/web/20190701231528/https://www.umassmed.edu/news/news-archives/2013/01/full-video-of-asc-opening-ceremony/|url-status=live}}</ref><ref>{{Cite web |date=2013-09-05 |title=Sherman Center website |url=https://www.umassmed.edu/shermancenter/ |access-date=2019-06-12 |website=University of Massachusetts Medical School |language=en |archive-date=July 1, 2019 |archive-url=https://web.archive.org/web/20190701231805/https://www.umassmed.edu/shermancenter/ |url-status=live }}</ref><ref>{{Cite web |title=UMASS Medical School, Albert Sherman Center {{!}} BR+A Consulting Engineers |url=https://www.brplusa.com/projects/umass-medical-school-albert-sherman-center |access-date=2022-06-11 |website=www.brplusa.com |archive-date=January 19, 2022 |archive-url=https://web.archive.org/web/20220119114224/https://brplusa.com/projects/umass-medical-school-albert-sherman-center |url-status=live }}</ref>

===Lamar Soutter Library===
===Lamar Soutter Library===
<p>Named for the founding dean of the [[#School of Medicine]], the [[#Lamar Soutter]] Library at UMMS contains more than 288,000 volumes and is the state's leading source of biomedical information via inter‑library loan. The only public medical library in the state, it is the Regional Medical Library for New England and one of only eight such regional libraries that comprise the National Library of Medicine. </p>
Named in honor of [[Lamar Soutter]] (founding dean of the School of Medicine), the Lamar Soutter Library at UMMS contains more than 288,000 volumes and is the state's leading source of biomedical information for inter‑library loan. The only public medical library in the state, it is the regional medical library for New England and one of eight regional libraries comprising the National Library of Medicine.

===Aaron Lazare Medical Research Building===
===Aaron Lazare Medical Research Building===
[[Image:Umass Medical School Lazare Research Building.jpg|thumb|left|Aaron Lazare Medical Research Building|alt=Blue glass multi-story building]]
<p>To support the more than 260 investigators working on advancements in the treatment of disease and injury, the Aaron Lazare Medical Research Building, a 360,000-square-foot, state-of-the-art research facility, opened in October of 2001. The ten-story structure, which is named for the [[#current chancellor]], expanded upon the Medical School’s existing 600,000 square feet in on-campus buildings and 83,000 square feet in the adjacent Massachusetts Biotechnology Research Park.</p>
To support the more than 260 investigators working on advancements in the treatment of disease and injury, the [[Aaron Lazare]] Medical Research Building (a {{convert|360000|sqft|m2|-3|adj=on}} research facility) opened in October 2001. The 10-story structure, named for the chancellor emeritus, expanded upon the medical school's existing {{convert|600000|sqft|m2|-4}} of campus buildings and {{convert|83000|sqft|m2|-2}} in the adjacent Massachusetts Biotechnology Research Park.
===Extended Campus===

<p>The UMMS extended campus includes the Brudnick Neuropsychiatric Research Institute, and labs and offices within the Massachusetts Biotechnology Research Park in Worcester; sites in Shrewsbury and Auburn; the Eunice Kennedy Shriver Center in Waltham; and the New England Newborn Screening Program and Massachusetts Biologic Laboratories in Jamaica Plain and Mattapan.</p>
==={{anchor|Extended Campus}}Extended campus===
==External Links==
The UMMS extended campus includes the Brudnick Neuropsychiatric Research Institute, labs and offices in the Massachusetts Biotechnology Research Park in Worcester; sites in Shrewsbury and Auburn; the Eunice Kennedy Shriver Center in Waltham and the New England Newborn Screening Program and Massachusetts Biologic Laboratories in Jamaica Plain and Mattapan. {{clear}}
* [http://www.umassmed.edu/ UMass Medical School]

* [http://www.cowc.org/ Colleges of Worcester Consortium]{{US-northeast-university-stub}}
==See also==
*[[UMass Memorial Health Care]]

==References==
{{reflist}}

==External links==
*[http://www.umassmed.edu/ Official website]


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[[Category:University of Massachusetts|Medical School]]
{{DEFAULTSORT:Massachusetts Medical School, University Of}}
[[Category:Schools of Medicine in the United States|Massachsetts]]
[[Category:UMass Chan Medical School| ]]
[[Category:Universities and colleges established in 1962]]
[[Category:Medical schools in Massachusetts]]
[[Category:University of Massachusetts campuses|Chan Medical School]]
[[Category:Universities and colleges in Worcester, Massachusetts|University of Massachusetts Medical School]]
[[Category:Buildings and structures in Worcester, Massachusetts]]
[[Category:Hospitals in Worcester, Massachusetts]]
[[Category:Public universities and colleges in Massachusetts|University of Massachusetts Medical School]]

Latest revision as of 11:43, 19 December 2024

University of Massachusetts
Chan Medical School
UMMS Logo
UMMS Logo
TypePublic medical school
Established1962
Parent institution
University of Massachusetts
AccreditationNECHE
Endowment$207.5 million (2018)[1]
ChancellorMichael Collins
PresidentMarty Meehan
StudentsMedicine: 608
Biomedical Sciences: 306
Nursing: 192
MD/PhD: 78
(2019)
Location
Worcester
,
Massachusetts
,
United States

42°16′37″N 71°45′45″W / 42.276815°N 71.762445°W / 42.276815; -71.762445
CampusUrban
ColorsBlue, white and black    
Websiteumassmed.edu

The UMass Chan Medical School is a public medical school in Worcester, Massachusetts. It is part of the University of Massachusetts system. It consists of three schools: the T.H. Chan School of Medicine, the Morningside Graduate School of Biomedical Sciences, and the Tan Chingfen Graduate School of Nursing. The school also operates a biomedical research enterprise and a range of public-service initiatives throughout the state.[2][3]

History

[edit]

The University of Massachusetts Medical School (UMMS) was established by the 162nd Massachusetts General Court in 1962 to provide residents of the commonwealth an opportunity to study medicine at an affordable cost and to increase the number of primary-care physicians practicing in the commonwealth's under-served areas.[4] The legislation was signed into law by Massachusetts Governor John Volpe.[5] The School of Medicine accepted its first class of 16 students in 1970. Six years later a 371-bed hospital opened on campus; the Graduate School of Biomedical Sciences opened in 1979, and the Graduate School of Nursing opened in 1986.

In 1998 the UMMS system of hospitals and clinics merged with Memorial Health Care to form UMass Memorial Health Care, the largest health-care provider in Central Massachusetts and clinical partner of UMMS.[6]

Name change

[edit]

In 2021 an unrestricted $175 million gift from the family of Hong Kong real estate developer Chan Tseng-hsi resulted in the name of the medical school, along with the biosciences and nursing schools, to be changed.[7]

Worcester Foundation for Biomedical Research

[edit]
Main article: Worcester Foundation for Biomedical Research

The research mission at UMMS was augmented in 1997 with the acquisition of the financially ailing Worcester Foundation for Biomedical Research, the Shrewsbury, Massachusetts institution where researchers developed the combined oral contraceptive pill during the early 1960s.

Academics

[edit]

School of Medicine

[edit]

Accredited by the Liaison Committee on Medical Education, the T.H. Chan School of Medicine grants the MD degree to its graduates. With the exception of MD/PhD students, degree candidates were formerly required to be Massachusetts residents, a policy which has changed beginning with the entering class of 2016. Approximately 165 students enroll annually, and more than 4,350 students have received medical degrees from UMMS. The School of Medicine has gained a national reputation for its primary-care program and consistently ranks in the top 10 percent of schools in the annual U.S. News & World Report guide, "America’s Best Graduate Schools". SCImago Journal Rank listed the university at No. 74 in the US and No. 248 globally.[8] Over half of each graduating class enters primary-care residencies, a trend underscoring the school's founding mission, though that figure has decreased in recent years. In addition, a high number of graduates practice throughout the state. UMass Medical is also accredited by the New England Commission of Higher Education.[9]

Academic rankings
Global
ARWU[11]151–200[10]
U.S. News & World Report[13]251[12]

Graduate School of Biomedical Sciences

[edit]

The Morningside Graduate School of Biomedical Sciences (GSBS) is a PhD-granting program that trains scientists in a specialty area with a broad background in the basic medical sciences in preparation for conducting research with direct relevance to human disease. According to the GSBS website, the school offers students a multidisciplinary program of study, in which they have freedom of choice in curriculum and in the selection of mentors for their graduate-thesis research.[14] Since the first class of seven students enrolled in 1979, more than 1000 students have earned PhDs from the GSBS.

Graduate School of Nursing

[edit]

Since the opening of the Tan Chingfen Graduate School of Nursing (GSN) in 1986, more than 600 students have obtained a nursing master's, post-master's or doctoral degree from the school. The GSN prepares professional and advanced practice nurses, nurse scientists and educators as leaders in nursing and health-care delivery to diverse populations through education, research, practice and service (according to the GSN website).[15]

Research

[edit]

UMMS researchers have made advances in a broad range of disease families, from HIV and infectious diseases to cancer, genetic disorders, diabetes and immune disease.[citation needed] UMMS faculty discovered the link between the immune system and type-1 diabetes, found the genetic cause underlying the third-most-common form of the muscular dystrophies, and established the fundamental difference between HIV and other retroviruses.[citation needed]

In the 1990s. UMMS Professor of Medicine Shan Lu, leader of the UMMS DNA-based flu vaccine efforts, worked to advance the development of a potential avian-flu vaccine.[16] Lu's team has also been recognized for its work in the creation of an HIV vaccine,[17] which in Phase I testing was found to generate antibody and T-cell responses in otherwise healthy people not infected with HIV.[18] In 1998, UMMS researcher Craig Mello (an investigator at the Howard Hughes Medical Institute) and his colleague Andrew Fire (of Stanford University, then of the Carnegie Institution in Washington, D.C.) discovered RNA interference (RNAi). They demonstrated that small pieces of double-stranded RNA had interfered with the expression of a gene whose coding sequence of DNA was similar to that of the RNA they tested. Mello and Fire received the 2006 Nobel Prize in Physiology or Medicine for their discoveries related to RNA interference.[19]

Federal and private research grants and contracts at UMCMS rose from about $2 million in 1977[citation needed] to more than $322 million in 2022[20] an increase of over 16,000% over forty-five years.

MassBiologics

[edit]

MassBiologics is the only publicly owned, non-profit FDA-licensed[21] manufacturer of vaccine[22] and other biologic products in the United States. First established in 1894, the University of Massachusetts Biologic Laboratory was re-established in 1997 by the Massachusetts legislature,[23] and oversight was transferred from the Department of Public Health to UMMS.[24]

In recent years, MassBiologics has been called upon to respond to the threat of SARS, avian flu, and rabies. MassBiologics has developed or collaborated on five “orphan products” over the past twenty years. [citation needed] MassBiologics continues to market its FDA-licensed Td (tetanus and diphtheria) vaccine, providing a substantial proportion of the U.S. requirement for this vaccine.[citation needed] MassBiologics participates in the discovery, production and clinical testing of monoclonal antibodies (including antibodies to Clostridioides difficile),[25] antibodies now known as actoxumab and bezlotoxumab In 2005, the firm opened an $80 million facility for monoclonal-antibody production. Co-developed with Serum Institute of India, it invented a fast-acting anti-Rabies drug called Rabies Human Monoclonal Antibody (RMAb).[26]

UMMS is extending its mission of public service through its Commonwealth Medicine initiative.[27]

Faculty

[edit]

Notable faculty members include:

Affiliates and clinical partners

[edit]
Main article: UMass Memorial Health Care

The hospital and clinical components of UMMS are part of UMass Memorial Health Care (UMMHC). UMass Memorial is a multibillion-dollar health-care system consisting of acute-care hospitals, ambulatory clinics and a network of primary care physicians and specialists throughout central Massachusetts.[31] With approximately 13,000 employees (including 1,500 physicians), UMMHC is the largest health-care provider in central Massachusetts.[31] Its flagship hospital (UMass Memorial Medical Center) straddles two campuses along Route 9 in Worcester, Massachusetts and is designated by the American College of Surgeons as a Level I Trauma Center.[31]

Its largest publicly funded affiliate in the field of cancer research is the Quality Assurance Review Center (QARC), located in Lincoln, Rhode Island. Supported by the National Cancer Institute (NCI) and the National Institutes of Health (NIH), QARC receives radiotherapy data from around 1,000 hospitals in the United States.[32]

UMMHC also maintains three community hospitals:[31]

Campus

[edit]
Angular, gray-and-white multi-story building
Albert Sherman Center

Albert Sherman Center

[edit]

The Albert Sherman Center, a 512,000 square foot biomedical research and education facility, was unveiled to the public on January 30, 2013, in a ribbon-cutting ceremony attended by Gov. Deval Patrick.[33][34][35]

Lamar Soutter Library

[edit]

Named in honor of Lamar Soutter (founding dean of the School of Medicine), the Lamar Soutter Library at UMMS contains more than 288,000 volumes and is the state's leading source of biomedical information for inter‑library loan. The only public medical library in the state, it is the regional medical library for New England and one of eight regional libraries comprising the National Library of Medicine.

Aaron Lazare Medical Research Building

[edit]
Blue glass multi-story building
Aaron Lazare Medical Research Building

To support the more than 260 investigators working on advancements in the treatment of disease and injury, the Aaron Lazare Medical Research Building (a 360,000-square-foot (33,000 m2) research facility) opened in October 2001. The 10-story structure, named for the chancellor emeritus, expanded upon the medical school's existing 600,000 square feet (60,000 m2) of campus buildings and 83,000 square feet (7,700 m2) in the adjacent Massachusetts Biotechnology Research Park.

Extended campus

[edit]

The UMMS extended campus includes the Brudnick Neuropsychiatric Research Institute, labs and offices in the Massachusetts Biotechnology Research Park in Worcester; sites in Shrewsbury and Auburn; the Eunice Kennedy Shriver Center in Waltham and the New England Newborn Screening Program and Massachusetts Biologic Laboratories in Jamaica Plain and Mattapan.

See also

[edit]

References

[edit]
  1. ^ "2018 REPORT ON ANNUAL INDICATORS University Performance Measurement System July 2018" (PDF). University of Massachusetts. Archived (PDF) from the original on July 1, 2019. Retrieved June 12, 2019.
  2. ^ "University of Massachusetts". Times Higher Education (THE). March 25, 2019. Archived from the original on February 15, 2023. Retrieved June 12, 2019.
  3. ^ "University of Massachusetts announces $175 Million transformational gift to its Medical School". UMass Chan. UMass Chan Medical School. September 5, 2013. Archived from the original on September 7, 2021. Retrieved September 7, 2021.
  4. ^ Feldberg, Michael (2015). UMass Boston at 50: A Fiftieth-Anniversary History of the University of Massachusetts Boston. Amherst, Massachusetts: University of Massachusetts Press. p. 5. ISBN 978-1625341693.
  5. ^ More, Ellen S. (2012). The University of Massachusetts Medical School, A History: Integrating Primary Care and Biomedical Research. Worcester, MA: University of Massachusetts Medical School. p. 16. doi:10.13028/e2m6-hs02.
  6. ^ "UMass Memorial Health Care - our Clinical Partner at UMMS". University of Massachusetts Medical School. February 22, 2014. Archived from the original on July 5, 2019. Retrieved June 12, 2019.
  7. ^ "University of Massachusetts announces $175 million transformational gift to its Medical School". UMass System. September 7, 2021.
  8. ^ "Scimago Institutions Rankings". www.scimagoir.com. Archived from the original on July 2, 2019. Retrieved May 27, 2019.
  9. ^ Massachusetts Institutions – NECHE, New England Commission of Higher Education, archived from the original on October 9, 2021, retrieved May 26, 2021
  10. ^ "ARWU World University Rankings 2016 | Academic Ranking of World Universities 2016 | Top 500 universities | Shanghai Ranking - 2016". Shanghai Ranking. Archived from the original on June 1, 2020. Retrieved May 27, 2019.
  11. ^ "2024 Academic Ranking of World Universities". ShanghaiRanking Consultancy. August 15, 2024. Retrieved August 21, 2024.
  12. ^ "Rankings". U.S. News & World Report. Archived from the original on March 9, 2018. Retrieved May 27, 2019.
  13. ^ "2024-2025 Best Global Universities Rankings". U.S. News & World Report. June 24, 2024. Retrieved August 9, 2024.
  14. ^ "Graduate School of Biomedical Sciences". University of Massachusetts Medical School. Archived from the original on May 7, 2012.
  15. ^ "Graduate School of Nursing". University of Massachusetts Medical School. Archived from the original on May 7, 2012.
  16. ^ "Shan Lu to lead International Society for Vaccines - UMass Medical School - Worcester". University of Massachusetts Medical School. December 15, 2013. Archived from the original on July 1, 2019. Retrieved June 12, 2019.
  17. ^ "UMMS receives $17.3 million to oversee manufacturing of HIV vaccine". University of Massachusetts Medical School. June 22, 2016. Archived from the original on July 1, 2019. Retrieved June 12, 2019.
  18. ^ "UMass Researchers Move Into Phase 1 Trial with HIV Vaccine". MD Magazine. Retrieved June 12, 2019.
  19. ^ "The Nobel Prize in Physiology or Medicine 2006". NobelPrize.org. Archived from the original on May 23, 2020. Retrieved June 12, 2019.
  20. ^ "About UMass Chan Medical School". University of Massachusetts Medical School. September 5, 2013.
  21. ^ "Alphabetical List of Establishments Licensed to produce Biologics including Product Approval Dates" (PDF). U.S. Food and Drug Administration. Archived (PDF) from the original on April 23, 2019. Retrieved December 16, 2019.
  22. ^ "Approved Products, Tetanus & Diphtheria Toxoids, Adsorbed, Manufacturer: MassBiologics, License #1779". U.S. Food and Drug Administration. Archived from the original on April 23, 2019. Retrieved December 16, 2019.
  23. ^ "Massachusetts General Law: Chapter 75, Section 43". www.malegislature.gov. Archived from the original on September 30, 2022. Retrieved September 2, 2011.
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