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'''Disseminated coccidioidomycosis''' is a systemic infection with ''[[Coccidioides immitis]]'', in which 15-20% of people develop [[skin lesion]]s.<ref name="Andrews">{{cite book |author1=James, William D. |author2=Berger, Timothy G. |title=Andrews' Diseases of the Skin: Clinical Dermatology |publisher=Saunders Elsevier |year=2006 |isbn=0-7216-2921-0 |display-authors=etal}}</ref>{{rp|315}}
'''Disseminated coccidioidomycosis''' is a systemic infection caused by ''[[Coccidioides immitis]]''. 15-20% of people with the infection develop [[skin lesion]]s.<ref name="Andrews">{{cite book |author1=James, William D. |author2=Berger, Timothy G. |title=Andrews' Diseases of the Skin: Clinical Dermatology |publisher=Saunders Elsevier |year=2006 |isbn=0-7216-2921-0 |display-authors=etal}}</ref>{{rp|315}} <!-- Consider adding the page number below in the number 1 reference. -->

== History of treatment ==
One of the earliest treatments for the disease was publicized in the ''New York State Journal of Medicine'' in 1959, in an article titled "Disseminated Coccidioidomycosis Treated with [[Amphotericin B]]". The case centered around a patient who was admitted to the U.S. Public Health Service Hospital in Seattle, Washington. Prior to the introduction of Amphotericin B, disseminated coccidioidomycosis had no specific chemotherapeutic treatment. Amphotericin B, a polyene antifungal antibiotic, was first trialed for this condition approximately three years earlier. Since then, multiple reports have highlighted the drug's clinical effectiveness in patients with coccidioidomycosis. <ref>{{Cite journal |last=La Barbera, M.D. |first=Salvatore A. |date=October 1, 1959 |title=Disseminated Coccidioidomycosis Treated with Amphotericin B |journal=New York State Journal of Medicine |volume=59 |issue=19 |pages=3644}}</ref>

{{Mycoses}}


== See also ==
== See also ==
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* [[List of cutaneous conditions]]
* [[List of cutaneous conditions]]


== References <!-- Should this References section be underneath the table? -->==
== References ==
{{reflist}}
{{reflist}}


{{Mycoses}}'''History of Treatment'''

In 1959 "Disseminated Coccidioidomycosis Treated with Amphotericin B" was published in the New York State Journal of Medicine, documenting perhaps one of the earliest uses of the drug, amphotericin B, for a patient who was admitted to the U.S. Public Health Service Hospital in Seattle, Washington. "Disseminated coccidioidomycosis had been lacking specific chemotherapeutic treatment until approximately three years ago when a polyene, antifungal antibiotic, amphotericin B, was tired. Since then there have been a number of reports on the beneficial clinical effect of the drug in patients with coccidioidomycosis. The reader is referred to Littman, Horowitz, and Swadey's article for a review of the salient features of coccidioidomycosis as well as the characteristics of amphotericin B. The purpose of this paper is to present another case of disseminated coccidioidomycosis treated with amphotericin B and followed for fourteen months. <ref>{{Cite journal |last=La Barbera, M.D. |first=Salvatore A. |date=Oct. 1, 1959 |title=Disseminated Coccidioidomycosis Treated with Amphotericin B |journal=New York State Journal of Medicine |volume=59 |issue=19 |pages=3644}}</ref>
[[Category:Mycosis-related cutaneous conditions]]
[[Category:Mycosis-related cutaneous conditions]]



Latest revision as of 10:12, 26 December 2024

Disseminated coccidioidomycosis
Other namesCoccidioidal granuloma
Characteristic skin granulomata on the forehead.
SpecialtyInfectious diseases

Disseminated coccidioidomycosis is a systemic infection caused by Coccidioides immitis. 15-20% of people with the infection develop skin lesions.[1]: 315 

History of treatment

[edit]

One of the earliest treatments for the disease was publicized in the New York State Journal of Medicine in 1959, in an article titled "Disseminated Coccidioidomycosis Treated with Amphotericin B". The case centered around a patient who was admitted to the U.S. Public Health Service Hospital in Seattle, Washington. Prior to the introduction of Amphotericin B, disseminated coccidioidomycosis had no specific chemotherapeutic treatment. Amphotericin B, a polyene antifungal antibiotic, was first trialed for this condition approximately three years earlier. Since then, multiple reports have highlighted the drug's clinical effectiveness in patients with coccidioidomycosis. [2]

See also

[edit]

References

[edit]
  1. ^ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: Clinical Dermatology. Saunders Elsevier. ISBN 0-7216-2921-0.
  2. ^ La Barbera, M.D., Salvatore A. (October 1, 1959). "Disseminated Coccidioidomycosis Treated with Amphotericin B". New York State Journal of Medicine. 59 (19): 3644.