Philip D'Arcy Hart: Difference between revisions
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{{Infobox scientist |
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| name = Philip D'Arcy Hart |
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'''Philip Montagu |
'''Philip Montagu D'Arcy Hart''', [[CBE]] (25 June 1900 – 30 July 2006) was a seminal British [[medical research]]er and pioneer in tuberculosis treatment. |
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==Personal life== |
==Personal life== |
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Philip D'Arcy Hart was the grandson of [[Samuel Montagu, 1st Baron Swaythling]]. |
Philip D'Arcy Hart was the grandson of [[Samuel Montagu, 1st Baron Swaythling]]. He was educated at [[Clifton College]].<ref>"Clifton College Register" Muirhead, J.A.O. p330: Bristol; J.W Arrowsmith for Old Cliftonian Society; April, 1948</ref> |
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In 1941, he married Ruth Meyer, later a medical gynaecologist. They had a son, the economist [[Oliver Hart (economist)|Oliver Hart]]. |
In 1941, he married Ruth Meyer (1913–2007), later a medical gynaecologist. They had a son, the economist [[Oliver Hart (economist)|Oliver Hart]]. |
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Philip D'Arcy Hart died at the age of 106 in 2006.<ref>{{cite web |url=http://www.genarians.com/In%20Memoriam%202006.html|title=Noted Nonagenarians & Centenarians |
Philip D'Arcy Hart died at the age of 106 in 2006.<ref>{{cite web |url=http://www.genarians.com/In%20Memoriam%202006.html|title=Noted Nonagenarians & Centenarians – In Memoriam 2006|publisher=generians.com }}</ref> |
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==Career== |
==Career== |
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Hart became a consultant physician at [[University College Hospital]] at the age of 34. Three years later, he joined the [[Medical Research Council (UK)|Medical Research Council]] (MRC). |
D'Arcy Hart became a consultant physician at [[University College Hospital]] at the age of 34. Three years later, he joined the [[Medical Research Council (UK)|Medical Research Council]] (MRC). He was a pioneer of [[evidence-based medicine]], conducting some of the earliest [[randomized controlled trial]]s on [[patulin]] in 1943 and [[streptomycin]] with [[Austin Bradford Hill]]. |
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Hart became involved with much of the MRC's early research into dust diseases in coal miners. He was a member of the MRC Streptomycin in Tuberculosis Trials Committee |
D'Arcy Hart became involved with much of the MRC's early research into dust diseases in coal miners. He was a member of the MRC Streptomycin in Tuberculosis Trials Committee, which is generally accepted as the first randomized clinical trial. At the age of 71, D'Arcy Hart published a seminal paper in the ''[[Journal of Experimental Medicine]]'', showing that the intracellular pathogen ''[[Mycobacterium tuberculosis]]'' avoids destruction in the cell's [[lysosome]]s by circumventing these organelles altogether—a trick now known to be used by many other intracellular pathogens. |
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He was a member of the [[Society for Social Medicine|Committee for the Study of Social Medicine]] set up in 1939, and later the [[Sigerist Society]], which discussed the theoretical and social aspects of medicine from a Marxist point of view. |
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==References== |
==References== |
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==External links== |
==External links== |
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*Tansey, Tilli. [http://www.jameslindlibrary.org/illustrating/articles/philip-montagu-darcy-hart-1900-2006 Obituary], James Lind Library. |
* Tansey, Tilli. [http://www.jameslindlibrary.org/illustrating/articles/philip-montagu-darcy-hart-1900-2006 Obituary], James Lind Library. |
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*Draper, Philip; Skehel, John. [ |
* Draper, Philip; Skehel, John. [https://www.theguardian.com/news/2006/aug/30/guardianobituaries.mainsection Obituary], ''The Guardian'', 30 August 2006. |
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* Armstrong, J. A.; Hart, P. D'Arcy. Response of Cultured Macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes. J Exp Med. 1971 Sep 1; 134(3): 713–740.[https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2139093/] |
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{{Authority control |
{{Authority control}} |
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{{Persondata <!-- Metadata: see [[Wikipedia:Persondata]]. --> |
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{{DEFAULTSORT:D'Arcy Hart, Philip}} |
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| SHORT DESCRIPTION = Epidemiologist |
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| DATE OF BIRTH = 25 June 1900 |
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| DATE OF DEATH = 30 July 2006 |
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{{DEFAULTSORT:Hart, Philip Darcy}} |
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[[Category:1900 births]] |
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[[Category:2006 deaths]] |
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[[Category:20th-century English medical doctors]] |
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[[Category:People educated at Clifton College]] |
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Latest revision as of 16:06, 31 December 2024
Philip D'Arcy Hart | |
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Born | 25 June 1900 |
Died | 30 July 2006 | (aged 106)
Nationality | British |
Scientific career | |
Fields | Medicine |
Institutions | University College Hospital |
Philip Montagu D'Arcy Hart, CBE (25 June 1900 – 30 July 2006) was a seminal British medical researcher and pioneer in tuberculosis treatment.
Personal life
[edit]Philip D'Arcy Hart was the grandson of Samuel Montagu, 1st Baron Swaythling. He was educated at Clifton College.[1]
In 1941, he married Ruth Meyer (1913–2007), later a medical gynaecologist. They had a son, the economist Oliver Hart.
Philip D'Arcy Hart died at the age of 106 in 2006.[2]
Career
[edit]D'Arcy Hart became a consultant physician at University College Hospital at the age of 34. Three years later, he joined the Medical Research Council (MRC). He was a pioneer of evidence-based medicine, conducting some of the earliest randomized controlled trials on patulin in 1943 and streptomycin with Austin Bradford Hill.
D'Arcy Hart became involved with much of the MRC's early research into dust diseases in coal miners. He was a member of the MRC Streptomycin in Tuberculosis Trials Committee, which is generally accepted as the first randomized clinical trial. At the age of 71, D'Arcy Hart published a seminal paper in the Journal of Experimental Medicine, showing that the intracellular pathogen Mycobacterium tuberculosis avoids destruction in the cell's lysosomes by circumventing these organelles altogether—a trick now known to be used by many other intracellular pathogens.
He was a member of the Committee for the Study of Social Medicine set up in 1939, and later the Sigerist Society, which discussed the theoretical and social aspects of medicine from a Marxist point of view.
References
[edit]- ^ "Clifton College Register" Muirhead, J.A.O. p330: Bristol; J.W Arrowsmith for Old Cliftonian Society; April, 1948
- ^ "Noted Nonagenarians & Centenarians – In Memoriam 2006". generians.com.
External links
[edit]- Tansey, Tilli. Obituary, James Lind Library.
- Draper, Philip; Skehel, John. Obituary, The Guardian, 30 August 2006.
- Armstrong, J. A.; Hart, P. D'Arcy. Response of Cultured Macrophages to Mycobacterium tuberculosis, with observations on fusion of lysosomes with phagosomes. J Exp Med. 1971 Sep 1; 134(3): 713–740.[1]