Independent review: Difference between revisions
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financial interests affect research results - British Medical Journal confirms this |
DoctorKubla (talk | contribs) Redirecting to peer review – there was a strong consensus on the talk page, and here, to merge these articles, but I can't see anything worth merging that isn't already covered in the target article |
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#REDIRECT [[Peer review]] |
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{{for|the title of several magazines, journals and newspapers|Independent Review}} |
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'''Independent review''' of scientific results is the cornerstone of scientific accountability (see also [[peer review]]). By giving other scientists access to one's own data and methods (see [[data sharing]]), and giving them an opportunity to gauge the [[reproducibility]] of one's results, one ensures that errors due to incompetence, unconscious bias, or other causes can be found by others. It's the scientific version of [[proofreading]]. |
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An important part of the independent review process is [[anonymous peer review]] of [[scientific paper]]s before they are published in [[scientific journal]]s. |
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Sometimes researchers will bypass the pre-publication review process (see "[[science by press conference]]") or will refuse to share their data and methods with other scientists. In general, the [[scientific community]] frowns on this, as it makes it difficult or even impossible for other scientists to verify the data and interpretations of the research. |
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It is considered common knowledge that financial interests affect research results, and many people believe that funding can influence a scientist's findings. In the well known tobacco industry case, manufacturers funded studies seeming to prove that tobacco smoking was harmless. Scientists whose funding did not come from tobacco companies eventually proved a link between [[smoking and cancer]]. |
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The British Medical Journal reported that, "Systematic bias favours products which are made by the company funding the research." [http://www.ncbi.nlm.nih.gov/pmc/articles/PMC156458/ BMJ. 2003 May 31; 326(7400): 1167.] |
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Another possible reason for bypassing traditional peer review is when reporting results which are radically at odds with mainstream scientific views. In several historical cases, discoveries announced in this way have eventually reached the mainstream (see [[Semmelweiss]] and his theory of an "invisible substance" infecting women after childbirth; see also [[Continental drift]]). |
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The [[Office of Research Integrity]] employs independent reviewers to guard against [[scientific misconduct]].<ref> [http://ori.hhs.gov/research/intra/documents/gallup_finalreport.pdf Final Report: Observing and Reporting Suspected Misconduct in Biomedical Research]</ref> |
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The state of [[California]] uses independent review to evaluate [[conservation]] proposals and to ensure that the general public can understand scientific publications written in mind-numbingly foggy techincal prose. |
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* ... California law, which requires independent scientific review at several stages of the conservation planning process, “so consultants working for counties or developers are not able to get away with using flawed scientific methodologies.” The published reports of such independent reviews can help the public navigate an otherwise impenetrable, seemingly arcane debate.<ref name=plos> [http://www.plos.org/cms/node/235 PLOS] </ref> |
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==Quotes== |
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* The best means for assessing risks and benefits is through independent review of the proposed research by individuals who have no direct vested interest in its outcome.<ref name=nih> [http://www.ncbi.nlm.nih.gov/bookshelf/br.fcgi?book=nap10508&part=a20006031ddd00066 Back to Basics: Scientific, Conflict of Interest, and Ethical Review of Research Protocols]</ref> |
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* A central tenet in the protection of research participants is the independent review of research protocols to assess their scientific merit and ethical acceptability. |
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* All protocols involving human participants should undergo an independent and rigorous scientific review to assess scientific quality, the importance of the research to increase knowledge, and the appropriateness of the study methodology to answer a precisely articulated scientific and, in some cases, clinical question. For example, the design of clinical trials should be based on sound statistical principles and methodologies, including sample size, use of controls, randomization, population stratification, stopping rules, and the feasibility of relating endpoints to objectives.<ref name=nih /> |
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* But knowing a study is industry funded isn't enough. More important is having independent reviewers evaluate the validity of the study design, methods, protocols, and determine whether the conclusions are consistent with the data. This is how rigorous peer review is supposed to work. But peer review can miss fatal flaws in studies—even when authors provide disclosure statements. That's why many researchers working at the intersection of science and policy want to see transparent review processes and independent scientific review panels oversee research results destined for use in policymaking (or drug approval) decisions.<ref name=plos /> |
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==References== |
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<references /> |
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==See also== |
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*[[Independent medical review]] |
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{{science-stub}} |
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[[Category:Academic journals]] |
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[[Category:Peer_review]] |
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Latest revision as of 15:25, 18 March 2013
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