BH3-only family: Difference between revisions
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#REDIRECT[[Bcl-2_family#BH3-only_family]] |
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BH3-only family of proteins includes those of the '''Bcl-2 family''' proteins ([[http://en.wikipedia.org/wiki/Bcl-2]]), which contain only a single BH-domain. The BH3-only family members play a key role in promoting apoptosis. The BH3-only family members are Bad, Bim and others. Various apoptotoc stimuli induce expression and/or activation of specific BH3-only family members, which translocate to the mitochondria and initiate Bax/Bak-dependent apoptosis. |
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<references/>Abeloff's Clinical Oncology, 4th edition</references/> |
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Latest revision as of 23:55, 2 December 2017
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