Buphenine: Difference between revisions
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{{Short description|Medication}} |
{{Short description|Medication}} |
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{{Drugbox |
{{Drugbox |
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| image = Buphenine.svg |
| image = Buphenine.svg |
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| width = |
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<!--Clinical data--> |
<!-- Clinical data --> |
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| tradename = |
| tradename = Arlidin |
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| Drugs.com = {{drugs.com|international|buphenine}} |
| Drugs.com = {{drugs.com|international|buphenine}} |
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| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
| pregnancy_AU = <!-- A / B1 / B2 / B3 / C / D / X --> |
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| routes_of_administration = |
| routes_of_administration = |
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<!--Pharmacokinetic data--> |
<!-- Pharmacokinetic data --> |
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| bioavailability = |
| bioavailability = |
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| protein_bound = |
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| excretion = |
| excretion = |
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<!--Identifiers--> |
<!-- Identifiers --> |
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| CAS_number = 447-41-6 |
| CAS_number = 447-41-6 |
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| ATC_prefix = C04 |
| ATC_prefix = C04 |
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| ChEMBL_Ref = {{ebicite|correct|EBI}} |
| ChEMBL_Ref = {{ebicite|correct|EBI}} |
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| ChEMBL = 114655 |
| ChEMBL = 114655 |
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| synonyms = Nylidrin |
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<!--Chemical data--> |
<!-- Chemical data --> |
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| C=19 | H=25 | N=1 | O=2 |
| C=19 | H=25 | N=1 | O=2 |
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| SMILES = OC(c1ccc(O)cc1)C(NC(C)CCc2ccccc2)C |
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'''Buphenine''' |
'''Buphenine''', also known as '''nylidrin''' and sold under the brand name '''Arlidin''', is a [[Beta2-adrenergic agonist|β<sub>2</sub> adrenoreceptor agonist]]<ref name="pmid2857689">{{cite journal |vauthors=Mittag TW, Tormay A, Messenger M, Podos SM |title=Ocular hypotension in the rabbit. Receptor mechanisms of pirbuterol and nylidrin |journal=Invest Ophthalmol Vis Sci |volume=26 |issue=2 |pages=163–9 |date=February 1985 |pmid=2857689 |url=http://www.iovs.org/cgi/pmidlookup?view=long&pmid=2857689 |url-status=dead |archiveurl=https://archive.today/20130415011509/http://www.iovs.org/cgi/pmidlookup?view=long&pmid=2857689 |archivedate=2013-04-15 }}</ref> that acts as a [[vasodilator]].<ref>{{cite journal| vauthors=Freedman L| title=Arlidin: a new vasodilative sympathomimetic drug | journal=Angiology | year= 1955 | volume= 6 | issue= 1 | pages= 52–8 | pmid=14350296 | doi=10.1177/000331975500600106| s2cid=46317963 }}</ref> |
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It was developed as a chemical derivative of [[oxilofrine]], and first reported in the literature in 1950.<ref>{{cite journal| vauthors=Külz F, Schneider M| title=Über neue gefäßerweiternde Sympathomimetika |language=German |trans-title=On new vasodilative sympathomimetics | journal=Klin Wochenschr | year= 1950 | volume= 28 | pages= |
It was developed as a chemical derivative of [[oxilofrine]], and first reported in the literature in 1950.<ref>{{cite journal| vauthors=Külz F, Schneider M| title=Über neue gefäßerweiternde Sympathomimetika |language=German |trans-title=On new vasodilative sympathomimetics | journal=Klin Wochenschr | year= 1950 | volume= 28 | issue=31–32 | pages= 535–7| doi=10.1007/BF01481535 | pmid=14775050 }}</ref> |
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==See also== |
==See also== |
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*[[Isoxsuprine]] |
* [[Isoxsuprine]] |
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==References== |
==References== |
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{{Reflist}} |
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{{Other gynecologicals}} |
{{Other gynecologicals}} |
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{{Ionotropic glutamate receptor modulators}} |
{{Ionotropic glutamate receptor modulators}} |
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[[Category:Beta-Hydroxyamphetamines]] |
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[[Category:Beta2-adrenergic agonists]] |
[[Category:Beta2-adrenergic agonists]] |
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[[Category:NMDA receptor antagonists]] |
[[Category:NMDA receptor antagonists]] |
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[[Category: |
[[Category:4-Hydroxyphenyl compounds]] |
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[[Category: |
[[Category:Tocolytics]] |
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{{cardiovascular-drug-stub}} |
{{cardiovascular-drug-stub}} |
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{{genito-urinary-drug-stub}} |
{{genito-urinary-drug-stub}} |
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[[Category:Cerebral vasodilators]] |
Latest revision as of 14:37, 24 October 2024
Clinical data | |
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Trade names | Arlidin |
Other names | Nylidrin |
AHFS/Drugs.com | International Drug Names |
ATC code | |
Identifiers | |
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CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
ChEMBL | |
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.006.531 |
Chemical and physical data | |
Formula | C19H25NO2 |
Molar mass | 299.414 g·mol−1 |
3D model (JSmol) | |
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Buphenine, also known as nylidrin and sold under the brand name Arlidin, is a β2 adrenoreceptor agonist[1] that acts as a vasodilator.[2]
It was developed as a chemical derivative of oxilofrine, and first reported in the literature in 1950.[3]
See also
[edit]References
[edit]- ^ Mittag TW, Tormay A, Messenger M, Podos SM (February 1985). "Ocular hypotension in the rabbit. Receptor mechanisms of pirbuterol and nylidrin". Invest Ophthalmol Vis Sci. 26 (2): 163–9. PMID 2857689. Archived from the original on 2013-04-15.
- ^ Freedman L (1955). "Arlidin: a new vasodilative sympathomimetic drug". Angiology. 6 (1): 52–8. doi:10.1177/000331975500600106. PMID 14350296. S2CID 46317963.
- ^ Külz F, Schneider M (1950). "Über neue gefäßerweiternde Sympathomimetika" [On new vasodilative sympathomimetics]. Klin Wochenschr (in German). 28 (31–32): 535–7. doi:10.1007/BF01481535. PMID 14775050.