Beta-phosphoglucomutase: Difference between revisions
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==References== |
==References== |
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* {{cite journal | vauthors = Ben-Zvi R, Schramm M | date = 1961 | title = A phosphoglucomutase specific for beta-glucose 1-phosphate | journal = J. Biol. Chem. | volume = 236 | pages = 2186–2189 }} |
* {{cite journal | vauthors = Ben-Zvi R, Schramm M | date = 1961 | title = A phosphoglucomutase specific for beta-glucose 1-phosphate | journal = J. Biol. Chem. | volume = 236 | issue = 8 | pages = 2186–2189 | doi = 10.1016/S0021-9258(18)64053-0 | doi-access = free }} |
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* {{cite book | veditors = Boyer PD | title = The Enzymes | edition = 3rd | volume = 6 | date = 1972 | pages = 407–477 }} |
* {{cite book | veditors = Boyer PD | title = The Enzymes | edition = 3rd | volume = 6 | date = 1972 | pages = 407–477 }} |
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Latest revision as of 14:55, 22 September 2024
β-Phosphoglucomutase | |||||||||
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Identifiers | |||||||||
EC no. | 5.4.2.6 | ||||||||
CAS no. | 68651-99-0 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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In enzymology, a β-phosphoglucomutase (EC 5.4.2.6) is an enzyme that catalyzes the chemical reaction
- β-D-glucose 1-phosphate β-D-glucose 6-phosphate
Hence, this enzyme has one substrate, β-D-glucose 1-phosphate, and one product, β-D-glucose 6-phosphate.
This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is beta-D-glucose 1,6-phosphomutase. This enzyme participates in starch and sucrose metabolism.
Structural studies
[edit]20 structures have been solved for this enzyme PDB. Some of the accession codes are 1LVH, 1O03, 1O08, 1Z4N, 1Z4O, and 1ZOL. Most of these structures detail metal fluoride analogue complexes which are used to mimic different states along the reaction coordinate.
References
[edit]- Ben-Zvi R, Schramm M (1961). "A phosphoglucomutase specific for beta-glucose 1-phosphate". J. Biol. Chem. 236 (8): 2186–2189. doi:10.1016/S0021-9258(18)64053-0.
- Boyer PD, ed. (1972). The Enzymes. Vol. 6 (3rd ed.). pp. 407–477.