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Undid unverified claims and vanity edits 1265126115 by Preetifeb (talk). User Preetifeb engaged in an ongoing edit war on this page. Use of State Honours as titles is illegal in Indian Law.
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unless spouse and mother happen to have the same name, this appears to be a typo; removing the entry that has no source
 
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{{short description|Indian biochemist, molecular biologist (born 1960)}}
{{short description|Indian biochemist, molecular biologist (born 1960)}}
{{Use dmy dates|date=January 2019}}
{{Use dmy dates|date=January 2019}}
{{Use Indian English|date=January 2019}}
{{Use Indian English|date=January 2019}}
{{Infobox scientist
{{Infobox scientist
| name = Jayant B. Udgaonkar
| name = Jayant B. Udgaonkar
| image = Prof. Jayant B. Udgaonkar.jpg
| image = Prof. Jayant B. Udgaonkar.jpg
| alt =
| native_name = {{transl|mr|Jayanta Udgāṁvakara}}
| caption =
| native_name_lang = mr
| birth_date = {{Birth date and age|df=yes|1960|3|22}}
| birth_date = {{Birth date and age|1960|03|22}}
| birth_place = [[Maharashtra]], India
| birth_place = Maharashtra
| death_date =
| education = [[IIT Madras]] (MSc)
[[Cornell University]] (PhD)
⚫
| death_place =
| residence =
| alma_mater = [[St. Xavier's College, Mumbai]] (BSc)
| organization = [[National Centre for Biological Sciences]], [[Indian Institute of Science Education and Research, Pune | IISER Pune]]
| nationality = [[Indian nationality|Indian]]
| fields = {{ublist | [[Physical biochemistry]] }}
| known_for = [[Protein-folding]]
⚫
| spouse =
| workplaces = {{ublist | [[Indian Institute of Science Education and Research, Pune]] | [[Tata Institute of Fundamental Research]] | [[National Centre for Biological Sciences]] }}
| website = {{URL|https://sites.google.com/acads.iiserpune.ac.in/prof-udgaonkar-lab}}
| alma_mater = {{ublist | [[St. Xavier's College, Mumbai]] ([[University of Mumbai]]) }}
| doctoral_advisor = George P. Hess<br>Robert Lesh Baldwin
| doctoral_students =
| known_for = Studies on [[Protein folding]]
| awards = G. N. Ramachandran Gold Medal
}}
}}
'''Jayant Bhalchandra Udgaonkar''' ([[Marathi Language|Marathi]]: {{transl|mr|Jayanta Udgāṁvakara}}) is a molecular biologist studying the processes by which a random chain of amino acids stabilises into a functional structure during or after translation.<ref>{{Cite web |title=Jayant B. Udgaonkar - IISER Pune |url=https://www.iiserpune.ac.in/research/department/biology/people/faculty/regular-faculty/jayant-b-udgaonkar/348}}</ref><ref name=felicitation>{{cite web|title=Felicitation Event Honouring Prof. Jayant B. Udgaonkar at IISER Pune |url=https://www.youtube.com/watch?v=FytNVG5cvto}}</ref>
'''Jayant Bhalchandra Udgaonkar''' (born 1960) is a former [[Director (business)|Director]] and [[Professor]] of [[Biology]]<ref>{{Cite web |title=Jayant B. Udgaonkar - IISER Pune |url=https://www.iiserpune.ac.in/research/department/biology/people/faculty/regular-faculty/jayant-b-udgaonkar/348}}</ref> at the [[Indian Institute of Science Education and Research, Pune]]. Without any major scientific contribution, he has nevertheless established himself as a prominent protein-folding scientist amongst the local scientific community (for notable contributions in the field, see [[protein folding]]). In 2016, the [[Biophysical Journal]] published a retraction notice<ref> {{cite web |date= 7 December 2021 |title=Retraction Notice to: The Pathogenic A116V Mutation Enhances Ion-Selective Channel Formation by Prion Protein in Membranes |url=https://www.cell.com/biophysj/pdf/S0006-3495(21)00952-8.pdf |access-date= 24 September 2024 |publisher= Biophysical Society}} </ref> citing evidence of manipulation via duplication, mirroring, and rescaling of identical data in one of his papers.<ref> {{cite web |date= 26 April 2016 |title=The Pathogenic A116V Mutation Enhances Ion-Selective Channel Formation by Prion Protein in Membranes |url=https://www.cell.com/action/showPdf?pii=S0006-3495%2816%2930068-6 |access-date= 24 September 2024 |publisher= Biophysical Society}} </ref>

== Biography ==
== Early Life and Education ==
[[File:Protein structure.png|thumb|235px|Results of [[protein folding]] (This is not Dr. Udgaonkar`s own result).]]

⚫
Jayant Udgaonkar, born on 22 March 1960, did his studies in protein folding chemistry at [[St. Xavier's College, Mumbai]].<ref name="Profile on NCBS">{{cite web |date=2016 |title=Profile on NCBS |url=https://www.ncbs.res.in/sites/default/files/ju_cvbrief_jan16.pdf |access-date=15 October 2016 |publisher=National Centre for Biological Sciences}}</ref> Udgaonkar obtained his PhD in protein folding from [[Cornell University]] and carried out his postdoctoral research in protein folding from [[Stanford University]]. He propounded the protein folding hypothesis that ''initial [[hydrophobic collapse]]'' is the first stage in protein folding, which he demonstrated using a model protein and elucidated the various stages of protein folding and unfolding. His current work focuses on formation of [[amyloid|amyloid protein folding]].<ref name="Jayant Udgaonkar on Google Scholar">{{cite web |date=2016 |title=Jayant Udgaonkar on Google Scholar |url=https://scholar.google.ae/citations?user=UKyLWOQAAAAJ&hl=en |access-date=16 October 2016 |work=Author profile |publisher=Google Scholar}}</ref><ref name="Jayant Udgaonkar on ResearchGate">{{cite web |date=2016 |title=Jayant Udgaonkar on ResearchGate |url=https://www.researchgate.net/profile/Jayant_Udgaonkar |access-date=16 October 2016 |work=Author profile}}</ref>
Born on 22 March 1960 to [[Bhalchandra Udgaonkar]], a theoretical physicist, and Suhasini Udgaonkar, a renowned historian, Jayant Udgaonkar studied Chemistry at [[St. Xavier's College, Mumbai]] (BSc, 1979) and [[IIT Madras]] (MSc, 1981), and Biochemistry at [[Cornell University]].<ref name="felicitation" /><ref>{{cite book |last1=Phondke |first1=Bal |url=http://www.hbcse.tifr.res.in/data/pdf/bmu/udgaonkar-confe.pdf |title=B.M. Udgaonkar: Eminent Scientist and Educationist |last2=Sheth |first2=Parul R. |last3=Naik-Satam |first3=Suhas |last4=Deshpande |first4=A.P. |date=2007 |publisher=National Center for Science Communication; Homi Bhabha Centre for Science Communication |location=Mumbai}}</ref><ref name="Profile on NCBS">{{cite web |date=2016 |title=Profile on NCBS |url=https://www.ncbs.res.in/sites/default/files/ju_cvbrief_jan16.pdf |access-date=15 October 2016 |publisher=National Centre for Biological Sciences}}</ref>

== Protein Folding ==

⚫
While studying the kinetics of [[Acetylcholine receptor|acetylcholine receptors]] in response to the binding of [[ACh]] at [[Stanford University]], he was struck by the structural precision of protein molecules that enabled them to perform highly specialized tasks with extreme precision. Consequently, he focused his attention on the processes that make these structures possible, and what may go wrong in these highly accurate processes. In one of his earliest studies, he found that a certain ''[[hydrophobic collapse]]'' is the first stage in a typical protein folding process. His current work focuses on the formation of [[amyloid]]<nowiki/>s.<ref name="Jayant Udgaonkar on Google Scholar">{{cite web |date=2016 |title=Jayant Udgaonkar on Google Scholar |url=https://scholar.google.ae/citations?user=UKyLWOQAAAAJ&hl=en |access-date=16 October 2016 |work=Author profile |publisher=Google Scholar}}</ref><ref name="Jayant Udgaonkar on ResearchGate">{{cite web |date=2016 |title=Jayant Udgaonkar on ResearchGate |url=https://www.researchgate.net/profile/Jayant_Udgaonkar |access-date=16 October 2016 |work=Author profile}}</ref>


== Legacy ==
He is the son of noted scientist [[Bhalchandra Udgaonkar]].<ref>{{cite book|last1=Phondke|first1=Bal|last2=Sheth|first2=Parul R.|last3=Naik-Satam|first3=Suhas|last4=Deshpande|first4=A.P.|title=B.M. Udgaonkar: Eminent Scientist and Educationist|date=2007|publisher=National Center for Science Communication; Homi Bhabha Centre for Science Communication|location=Mumbai|url=http://www.hbcse.tifr.res.in/data/pdf/bmu/udgaonkar-confe.pdf}}</ref>
== Awards and Honors ==
== Awards and Honors ==
* Vigyan Shri Award under [[Rashtriya Vigyan Puraskar]] scheme (2024)<ref>{{cite web |title=Rashtriya Vigyan Puraskar (RVP) - 2024 : Final List of Awardees |url=https://awards.gov.in/Home/GoToIndex?filename=Award%2FCommunication%2F202488013634H24ZU2.pdf|website=awards.gov.in |publisher=CASU, Ministry of Home Affairs, Government of India |access-date=15 August 2024}}</ref><ref>{{cite news |title=Rashtriya Vigyan Puraskar: Chandrayaan-3 team and 32 others selected for first ever edition |url=https://economictimes.indiatimes.com/news/science/rashtriya-vigyan-puraskar-chandrayaan-3-team-and-32-others-selected-for-first-ever-edition-here-is-full-list/articleshow/112349033.cms?from=mdr |newspaper=The Economic Times | date=7 August 2024 |access-date=15 August 2024}}</ref>
* Vigyan Shri Award under [[Rashtriya Vigyan Puraskar]] scheme (2024).<ref>{{cite web |title=Rashtriya Vigyan Puraskar (RVP) - 2024 : Final List of Awardees |url=https://awards.gov.in/Home/GoToIndex?filename=Award%2FCommunication%2F202488013634H24ZU2.pdf|website=awards.gov.in |publisher=CASU, Ministry of Home Affairs, Government of India |access-date=15 August 2024}}</ref><ref>{{cite news |title=Rashtriya Vigyan Puraskar: Chandrayaan-3 team and 32 others selected for first ever edition |url=https://economictimes.indiatimes.com/news/science/rashtriya-vigyan-puraskar-chandrayaan-3-team-and-32-others-selected-for-first-ever-edition-here-is-full-list/articleshow/112349033.cms?from=mdr |newspaper=The Economic Times | date=7 August 2024 |access-date=15 August 2024}}</ref>
* Udgaonkar stood first in the BSc chemistry examinations of the [[University of Mumbai]] in 1979 protein folding.<ref name="Profile on NCBS" />
* Udgaonkar stood first in the BSc chemistry examinations of the [[University of Mumbai]] in 1979.<ref name="Profile on NCBS" />


== Selected bibliography ==
== Selected bibliography ==

Latest revision as of 18:16, 1 January 2025

Jayant B. Udgaonkar
Jayanta Udgāṁvakara
Born (1960-03-22) March 22, 1960 (age 64)
Maharashtra
EducationIIT Madras (MSc) Cornell University (PhD)
Alma materSt. Xavier's College, Mumbai (BSc)
Organization(s)National Centre for Biological Sciences, IISER Pune
Known forProtein-folding
Websitesites.google.com/acads.iiserpune.ac.in/prof-udgaonkar-lab

Jayant Bhalchandra Udgaonkar (Marathi: Jayanta Udgāṁvakara) is a molecular biologist studying the processes by which a random chain of amino acids stabilises into a functional structure during or after translation.[1][2]

Early Life and Education

Born on 22 March 1960 to Bhalchandra Udgaonkar, a theoretical physicist, and Suhasini Udgaonkar, a renowned historian, Jayant Udgaonkar studied Chemistry at St. Xavier's College, Mumbai (BSc, 1979) and IIT Madras (MSc, 1981), and Biochemistry at Cornell University.[2][3][4]

Protein Folding

While studying the kinetics of acetylcholine receptors in response to the binding of ACh at Stanford University, he was struck by the structural precision of protein molecules that enabled them to perform highly specialized tasks with extreme precision. Consequently, he focused his attention on the processes that make these structures possible, and what may go wrong in these highly accurate processes. In one of his earliest studies, he found that a certain hydrophobic collapse is the first stage in a typical protein folding process. His current work focuses on the formation of amyloids.[5][6]

Awards and Honors

Selected bibliography

  • Jayant B Udgaonkar, Robert L Baldwin (November 1990). "Early folding intermediate of ribonuclease A." Proceedings of the National Academy of Sciences. 87 (21): 8197–8201. Bibcode:1990PNAS...87.8197U. doi:10.1073/pnas.87.21.8197. PMC 54922. PMID 2236032.

References

  1. ^ "Jayant B. Udgaonkar - IISER Pune".
  2. ^ a b "Felicitation Event Honouring Prof. Jayant B. Udgaonkar at IISER Pune".
  3. ^ Phondke, Bal; Sheth, Parul R.; Naik-Satam, Suhas; Deshpande, A.P. (2007). B.M. Udgaonkar: Eminent Scientist and Educationist (PDF). Mumbai: National Center for Science Communication; Homi Bhabha Centre for Science Communication.
  4. ^ a b "Profile on NCBS" (PDF). National Centre for Biological Sciences. 2016. Retrieved 15 October 2016.
  5. ^ "Jayant Udgaonkar on Google Scholar". Author profile. Google Scholar. 2016. Retrieved 16 October 2016.
  6. ^ "Jayant Udgaonkar on ResearchGate". Author profile. 2016. Retrieved 16 October 2016.
  7. ^ "Rashtriya Vigyan Puraskar (RVP) - 2024 : Final List of Awardees" (PDF). awards.gov.in. CASU, Ministry of Home Affairs, Government of India. Retrieved 15 August 2024.
  8. ^ "Rashtriya Vigyan Puraskar: Chandrayaan-3 team and 32 others selected for first ever edition". The Economic Times. 7 August 2024. Retrieved 15 August 2024.
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