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== Species ==

This page doesn’t mention what species have a Pineal gland.—[[User:GJK|GJK]] 10:33, 19 October 2005 (UTC)

I have no idea what Gray's Anatomy means by "animal matter" in the second paragraph of the [[Pineal gland#Structure and composition|structure and composition section]]. -- [[User:Phyzome|<nowiki></nowiki>]] [[User:Phyzome|Phyzome]] is [[User talk:Phyzome|Tim McCormack]] 22:44, 2004 Dec 8 (UTC)

I think the ''animal matter'' refers to a complex of proteins. The associated anatomical structure is really peripherial. I guess removing it should be the best for the article... [[User:moosattack|moostattack]]

==Epiphysis & Epiphyseal==

According to my lectures on Human Biology and my "Henderson's Dictionary of Biological terms", epiphysis pertains to bone, while epiphyseal refers to the gland. Many sources on the net neglect this distinction and talk about only bones or mistakenly use the same term for both subjects. Anatomy terms are not double in meaning so epiphysis can and does mean only bone while the gland is refered to largely as the pineal but epiphyseal, although rare, is the correct term for the gland. I've changed the synonim in the article accordingly but had it reverted by user Sammyj. Sammy, one anatomical term cannot have two such differents meanings, period. added by 193.77.9.207

:I'm sorry to burst your bubble, but often terms, even medical, refer to more than one thing. Epiphysis also refers to the pineal gland. You can check [http://education.yahoo.com/reference/gray/subjects/subject?id=276 Gray's Anatomy] or you can enter the term in Pubmed and see that researchers use the term for both the pineal and bone end! Finally, epiphyseal is an adjective, not a noun. [[User:Sammyj|Sammyj]] 11:25, 16 March 2007 (UTC) P.S. Other examples off the top of my head are Medulla (adrenal or oblongata) and cortex (cerebral or kidney).

::Hehe, bubble bursted, but in a positive way. English is not my natural language, so when reading too fast, I sometimes miss important details or misinterpret the text I've read. But it is peculiar that "epiphysis" has two such different meanings. Prehaps the explanation lies in its latin source? I'll check. -added by 08:37, 1 April 2007, 213.250.59.37

== Images ==


I think this article is in desperate need of images. The description of where this important gland sounds like ancient Greek to someone that knows nothing about the brain and it's anatomy. [[User:JoeHenzi|JoeHenzi]] 18:40, 5 Apr 2005 (UTC)


== Blood Pressure ==
== Blood Pressure ==
Line 30: Line 24:


The description in "Functions" is vague. Melatonin usally increases potassium channel conductance thereby slowing down the heart rate and possibly relaxing the endothelium (haven't checked this). [[user:moosattack|moosattack]]
The description in "Functions" is vague. Melatonin usally increases potassium channel conductance thereby slowing down the heart rate and possibly relaxing the endothelium (haven't checked this). [[user:moosattack|moosattack]]

== pineal cyst ==

I have a cyst on my pineal gland is that dangerous?
Does this have anything to do with balance?

: You should consult a medical doctor, not wikipedia, for such advice :) Good luck, [[User:Nimur|Nimur]] 14:34, 29 May 2006 (UTC)

== Doesnt this gland also produce Serotonin? ==

I read this at http://www.chm.bris.ac.uk/motm/serotonin/introduction.htm

Is that true? If so, shouldn't it be added so it says it produces 'melatonin' and 'serotonin'. I believe the endocrine system would need to be edited too.

== question for moosattack ==

What causes the pineal gland to calcify and is there any possible connection between the pineal gland and diabetes ?

This is not a science answer but a philosophical one. Suppose that the pineal is an antenna to the universal mind, designed to pick up vibrations/waveforms from external sources (I have been told of studies in Biology where a leaded hood is placed over a birds head and while wearing this hood, they no longer display instinctual behaviors), then maybe when we teach our children to "stop daydreaming and pay attention" to stimuli from our other senses, the pineal calcifies from lack of use. I also have heard that when a human dies, the pineal expands and shatters this calcified shell leaving "brain sand". [[User:72.35.34.145|72.35.34.145]] 19:37, 2 September 2007 (UTC)


=="Seat of the Soul"==
While I've heard this in every neuroanatomy class I've taken, I've never seen a reference given. After some searching, it appear it's from Descartes' ''Treatise of Man''. Note I haven't checked this myself yet, but I found that information here: http://plato.stanford.edu/entries/pineal-gland/#2 [[User:Semiconscious|<font color="#6D603B">Semiconscious</font>]] ([[User talk:Semiconscious|<font color="#6D603B"><small>talk</small></font>]] · [http://socrates.berkeley.edu/~btvoytek <font color="#6D603B"><small>home</small></font>]) 20:04, 28 December 2005 (UTC)


== Fluoride ==
== Fluoride ==
Line 58: Line 29:
There is no reputable evidence that fluoride has any influence on humman sexual maturity. In fact, the contrary exists. So, let's just drop this line in the article until peer-reviewed data is available.
There is no reputable evidence that fluoride has any influence on humman sexual maturity. In fact, the contrary exists. So, let's just drop this line in the article until peer-reviewed data is available.


Sorry, but this is not scientific - if "the contrary exists" - well then - we look forward to the sources? where are they? <!-- Template:Unsigned IP --><small class="autosigned">—&nbsp;Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/80.108.129.198|80.108.129.198]] ([[User talk:80.108.129.198#top|talk]]) 20:48, 28 March 2021 (UTC)</small> <!--Autosigned by SineBot-->
== Fluoride Accumulation in Pineal Gland ==

<small>Restored anonymous comment</small>

An [http://en.wikipedia.org/wiki/Special:Contributions/211.30.166.199 anonymous user] posted this link, purporting "proof" of fluoride accumulation: [http://www.newmediaexplorer.org/sepp/2006/12/30/fluoride_accumulates_in_pineal_gland.htm]

<small>Discussion follows.</small>

:A study exists that claims accumulation of fluoride in the pineal. The standard errors of the measurements are huge, however <ref>Luke J. Fluoride deposition in the aged human pineal gland. Caries Res. 35(2):125-8, 2001. PMID 11275672</ref>. [[User:AlbertHall|AlbertHall]] 20:36, 25 May 2007 (UTC)
::Furthermore, the original source cited probably does not satisfy [[WP:Reliable sources]]. AlbertHall, it is best [[WP:TALK#Others.27_comments|not to modify the text of another user's comments]] on a talk page; I will restore their link even though I disagree with it. [[User:Nimur|Nimur]] 21:44, 25 May 2007 (UTC)
:::Sorry, forgot that I was at discussion page and not the actual article. [[User:AlbertHall|AlbertHall]] 21:50, 25 May 2007 (UTC)

== Third Eye ==
Hi, I just want to emphasize the following viewpoint. I understand Wikipedia aims to be encyclopedic and present all sides of an issue, but we need to prevent pseudoscience from discoloring all of our articles, including this one. Some of the previous edits have made strong claims about the psycho-mystical ''third eye'' and pineal gland connection. While we should mention this as a historic or philosophical angle, the best way to present this is in a clearly labeled sub-heading, such as "Philosophy" or "Mysticism." This will help prevent people from confusing science and medical fact from religious or new-age ideas.

: Also just want to reiterate the distinction between fact and theory. Even the non-New-Age elements in this article sort of blur the distinction sometimes. (Particularly noting the evolutionary biology elements - at best, these are speculations based on evidence, no matter how solid that evidence is)... even these should be adequately discussed and cited.
[[User:Nimur|Nimur]] 02:29, 3 April 2006 (UTC)

I hear that the pineal gland secretes melatonin, which produces Melalin, which by websters definition is any of a class of insoluble pigments that are found in all forms of animal life and account for the dark color of skin, hair, fur, scales, feathers, etc. and is the greatest or most active in African or Afrocentric peoples, and isnt calcified. If it is in the brain, believe me it is there for a reason.

: Regarding fact and theory: Whilst most 'post-structuralists' laugh themselves out of whatever club they choose to join, I think altering the title of this section to Mythologies Cultures and Philosophies... is a valid and arguably logical shift to include the grey-areas. Bataille's contribution to science and logic is small, but his cultural cache is high- having investigated the role of rationale and myth in regards to the pineal (and more lucidly elsewhere) I think this reviewed section (under the wing of Denis Hollier) may offer a good pathway for peoples looking at the intersections of fact and fiction (re: Third Eye)- J.N Nov 2006

...To claim "is great if not well understood" is both emphasising a unqualified ambiguity in the term "greatness" and a superior understanding ("well understood"); which is debatable.

== And drug abuse ==
could not understand the following passage.

:Reports in rodents suggest that the pineal gland may influence the actions of drugs of abuse such as cocaine [1] and antidepressants such as fluoxetine (Prozac)[2]; and contribute to regulation of neuronal vulnerability[3].

"may influence the actions of drugs of abuse such as cocaine" ???
What does it mean? Can someone who knows more please correct it. Thanks--[[User:Pietrosperoni|Pietrosperoni]] 12:48, 21 July 2006 (UTC)



== Pineal Gland and DMT ==

The pineal gland does produce small amounts DMT, it is documented: Guchhait RB "Biogenesis of 5-methoxy-N,N-dimethyltryptamine in human pineal gland." J Neurochem 1976 Jan ;26(1):187-90 PMID:1255170. Also trace amounts can be found in the body and urine, all documented.

:The paper does not describe the presence of DMT or, for that matter, of 5-methoxy-N,N-dimethyltryptamine in the human pineal. It does describe the ability to use pineal extracts <i>in vitro</i> to synthesize 5-methoxy-N,N-DMT if provided with the appropriate substrate. There is no evidence to date for pineal synthesis of DMT <i>in vivo</i>.

::What is required for making evident the pineal synthesis of DMT in bodies alive - in vivo? I'm also curious of what is noted as 'appropriate substrate' for synthesizing 5-methoxy-N,N-DMT? Is such substrate also possibly endogenic? I'm curious of this also because of the paramount challenges Dr. [[Rick Strassman]], the author of the book ''DMT - The spirit molecule,'' experienced along his project. [[Rick Strassman]] was in the position to become the first researcher to use humans, not merely animal testing, in studies on [[psychedelics]], or [[entheogenic]] substances, after 20 years intermission-period in the [[United States of America]]. <small>—Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[User:Xact|Xact]] ([[User talk:Xact|talk]] • [[Special:Contributions/Xact|contribs]]) 21:42, 22 January 2008 (UTC)</small><!-- Template:Unsigned --> <!--Autosigned by SineBot-->

:::It is rather simple: blood needs to be assayed for the presence of DMT, as that is how it would get from the pineal into the brain (the pineal is outside of the blood-brain barrier). To date, DMT has not been found endogenously in human blood. [[User:AlbertHall|AlbertHall]] ([[User talk:AlbertHall|talk]]) 16:21, 23 January 2008 (UTC)

Actually, I believe that trace amounts have been found in human blood. Either way, there has never been found DMT in the Pineal Gland itself. According to Strassman, DMT occurs in the bodies of both humans and subhuman animals, in subthreshold amounts, and according to other research the chemicals needed to synthesize it in the body are found in high concentrations in Pineal tissue, so it is not unreasonable to come to the speculative conclusion that the Pineal Gland is where it is synthesized. [[User:Silverring06|Silverring06]] ([[User talk:Silverring06|talk]]) 15:56, 11 March 2008 (UTC)

:This is where the Wikipedia runs into trouble - quoting people that have not actually made the effort to examine their hypotheses and publish peer-reviewed papers (or find others that have). There are two problems with the statement "I believe that trace amounts have been found in human blood." First, belief is not proof, so a citation would be useful (no criticism intended). Second, depending on the actual concentration, a trace amount may or may not be able to activate a receptor proposed to elicit the response hypothesized. [[User:AlbertHall|AlbertHall]] ([[User talk:AlbertHall|talk]]) 19:18, 11 March 2008 (UTC)

::Well, I have no intention of changing anything in the article proper until I have verified my sources. As a matter of fact, I think that the mention DMT is granted is enough. Give me time to access my book, and you can have all the citations (and corrections to what I've recalled from memory) you need.
== Elfen Lied ==

In the manga [[Elfen Lied]], the Diclonius have special powers that are the result of an enlarged and a vastly developed pineal gland. Should that be mentioned in the article under that cultures section? <small>—The preceding [[Wikipedia:Sign your posts on talk pages|unsigned]] comment was added by [[Special:Contributions/72.80.172.222|72.80.172.222]] ([[User talk:72.80.172.222|talk]]) 15:47, 10 February 2007 (UTC).</small><!-- HagermanBot Auto-Unsigned -->

: Probably not. See our [[WP:Notability]] guidelines. [[User:Nimur|Nimur]] 19:27, 18 February 2007 (UTC)


== Effects of [[Quran]] ==

I removed the following section that lacks [[attribution]] it also seems out of place in an otherwise excellently researched article, perhaps if there is any merit to it we could come to some better wording and perhaps some [[attribution]] [[User:SallyBoseman|SallyBoseman]] 02:02, 6 April 2007 (UTC)


According to a recent study by Dr. Ahmed El Kadi, of Akber Clinic in [[Panama]], [[Florida]], the recitiation or listening of the [[Quran]], the [[Islam]]ic Holy Scripture. "The echo of sound has a medical effect and is now widely utilized," says Dr. Greenberg. "The recitation of or listening to the Qur'an has an effect on the body, the heart and the mind. It is said that the [[Arabic]] letter Alif echoes to the heart and the letter Ya echoes to the Pineal Gland in the brain.


== footnote [7] wrong? ==
Dr. El Kadi conducted and published the effects of listening to [[Quran]]ic recitation of [[physciologica]]l paremeters (ie. the [[heart]], [[blood pressure]] and [[muscle tension]]), and reported improvement in all factors, irrespective of whether the listener was a [[Muslim]] or non-[[Muslim]], [[Arab]] or non-[[Arab]].


In footnote [7], the referenced article doesn't seem to discuss "A few more developed vertebrates have lost pineal glands over the course of their evolution" like the statement states. Correction needed here I think! See, "A few more developed vertebrates have lost pineal glands over the course of their evolution.[7]".
:This is one person's idea - there is neither other philosophical, Islamic nor refereed scientific support for this concept. -5HTman 02:14, 6 April 2007 (UTC)


If I am wrong or you find the correct article indicated what the statement says, I would love to hear about it. <!-- Template:Unsigned IP --><small class="autosigned">—&nbsp;Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/73.153.146.226|73.153.146.226]] ([[User talk:73.153.146.226#top|talk]]) 02:29, 26 July 2020 (UTC)</small> <!--Autosigned by SineBot-->
==Paired structure==
The article as it stands right now is slightly contradictory, that the pineal gland is the only unpaired structure in the brain and that it under microscope has two hemispheres.[[User:Brallan|Brallan]] 10:30, 23 April 2007 (UTC)


== Misleading Image ==
== Descartes mind/body diagram ==


Why is Descartes mind/body diagram on this page? He was wrong about the function of the Pineal gland, and the diagram does not depict the operation of the pineal gland like the caption says. <!-- Template:Unsigned IP --><small class="autosigned">—&nbsp;Preceding [[Wikipedia:Signatures|unsigned]] comment added by [[Special:Contributions/71.84.127.250|71.84.127.250]] ([[User talk:71.84.127.250#top|talk]]) 21:10, 26 October 2020 (UTC)</small> <!--Autosigned by SineBot-->
The image in the upper right, Illu_endocrine_system.jpg shows the anterior portion of the brain facing the left side of the screen. The backdrop image of the head should also face towards the left side of the screen instead of facing out of the screen. [[User:Apenton|Apenton]] 15:51, 23 September 2007 (UTC)
:The image - a famous one among neuroscientists and neuroanatomists - is displayed in the Society and culture section where the true pineal function and structure are not intended to be defined as we understand them in the 21st century - the main article sections adequately represent them. [https://n.neurology.org/content/94/15_Supplement/914 Here's a 2020 view published in Neurology.] There is some historical significance to the image, showing it had the attention of people studying the brain nearly 400 years ago. [[User:Zefr|Zefr]] ([[User talk:Zefr|talk]]) 21:31, 26 October 2020 (UTC)


== Discovery of the purpose of the Pineal Gland ==
== Citation needed? ==


Sorry - the ancient greeks were not the original 'discoverers' of the mystical qualities or asking wider questions as to the purpose of the gland. The purpose or understanding of the pineal gland has been explored by all animist and mystical societies since the dawn of time. Someone with energy and time should update the page and place a more accurate chronological of its exploration, perception and understanding. [[Special:Contributions/217.61.229.4|217.61.229.4]] ([[User talk:217.61.229.4|talk]]) 10:32, 27 November 2024 (UTC)
Is the citation really needed for the connection between the intellect and the pineal gland? The references before it seem sufficient.
[[User:Musically ut|Musically ut]] ([[User talk:Musically ut|talk]]) 18:02, 24 November 2007 (UTC)

Latest revision as of 10:32, 27 November 2024

Blood Pressure

[edit]

The third paragraph under "Functions" starts with, 'It also contains a substance which if injected intravenously causes fall of blood-pressure.' Is this supposed to refer to the correlation between blood pressure and Melatonin production?

The description in "Functions" is vague. Melatonin usally increases potassium channel conductance thereby slowing down the heart rate and possibly relaxing the endothelium (haven't checked this). moosattack

Fluoride

[edit]

There is no reputable evidence that fluoride has any influence on humman sexual maturity. In fact, the contrary exists. So, let's just drop this line in the article until peer-reviewed data is available.

Sorry, but this is not scientific - if "the contrary exists" - well then - we look forward to the sources? where are they? — Preceding unsigned comment added by 80.108.129.198 (talk) 20:48, 28 March 2021 (UTC)[reply]

footnote [7] wrong?

[edit]

In footnote [7], the referenced article doesn't seem to discuss "A few more developed vertebrates have lost pineal glands over the course of their evolution" like the statement states. Correction needed here I think! See, "A few more developed vertebrates have lost pineal glands over the course of their evolution.[7]".

If I am wrong or you find the correct article indicated what the statement says, I would love to hear about it. — Preceding unsigned comment added by 73.153.146.226 (talk) 02:29, 26 July 2020 (UTC)[reply]

Descartes mind/body diagram

[edit]

Why is Descartes mind/body diagram on this page? He was wrong about the function of the Pineal gland, and the diagram does not depict the operation of the pineal gland like the caption says. — Preceding unsigned comment added by 71.84.127.250 (talk) 21:10, 26 October 2020 (UTC)[reply]

The image - a famous one among neuroscientists and neuroanatomists - is displayed in the Society and culture section where the true pineal function and structure are not intended to be defined as we understand them in the 21st century - the main article sections adequately represent them. Here's a 2020 view published in Neurology. There is some historical significance to the image, showing it had the attention of people studying the brain nearly 400 years ago. Zefr (talk) 21:31, 26 October 2020 (UTC)[reply]

Discovery of the purpose of the Pineal Gland

[edit]

Sorry - the ancient greeks were not the original 'discoverers' of the mystical qualities or asking wider questions as to the purpose of the gland. The purpose or understanding of the pineal gland has been explored by all animist and mystical societies since the dawn of time. Someone with energy and time should update the page and place a more accurate chronological of its exploration, perception and understanding. 217.61.229.4 (talk) 10:32, 27 November 2024 (UTC)[reply]

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