Jump to content

Tobacco: Difference between revisions

From Wikipedia, the free encyclopedia
Content deleted Content added
minor edit.
Citation bot (talk | contribs)
Add: bibcode, date. | Use this bot. Report bugs. | Suggested by Whoop whoop pull up | #UCB_webform 305/662
 
Line 1: Line 1:
{{short description|Agricultural product processed from the leaves of plants in the genus Nicotiana}}
{{About||the plant genus|Nicotiana|the American electronic musician|Tobacco (musician)}}
{{cs1 config|name-list-style=vanc}}

{{Distinguish|Tabacco (disambiguation){{!}}Tabacco|Tabaco|Tabasco|Tobago}}
{{See also|Tobacco smoking}}
{{About||the plant genus|Nicotiana|other uses|Tobacco (disambiguation) }}
{{Use mdy dates|date=March 2023}}
{{Infobox botanical product
| product = Tobacco, tobacco cigarette
| image = DunhillLightFlake.jpg
| caption = Tobacco flakes, sliced from pressed plugs
| plant = ''[[Nicotiana]]''
| part = [[Leaf]]
| origin = [[The Americas]]
| active = [[Nicotine]], [[harmine]]
| uses = [[Recreational drug use|Recreational]], Sacred, Medical, Religious, Traditional, Peacemaking
| legal_AU = Unscheduled
| legal_BR = E
| legal_CA = Unscheduled
| legal_DE = Unscheduled
| legal_UK = GSL
| legal_US_comment = Unscheduled
| legal_UN = Unscheduled
| legal_status = In general, legal and regulated as a controlled substance for recreational use in most countries, tobacco smuggling or homemade tobacco making or growing is illegal. See [[tobacco control]]
}}
{{Tobacco}}
{{Tobacco}}
[[File:A traditional tobacco drying kiln in Myrtleford, Victoria, Australia.jpg|thumb|Tobacco drying kiln in [[Myrtleford|Myrtleford, Victoria, Australia]], 2018. This kiln was built in 1957, and moved to Rotary Park in 2000. Kilns of this design were built from the early 1930s through to the late 1960s.]]
'''Tobacco''' is an [[agricultural]] product processed from the [[leaves]] of plants in the genus ''[[Nicotiana]]''. It can be consumed, used as an organic pesticide and, in the form of nicotine tartrate, it is used in some medicines.<ref>[http://student.britannica.com/comptons/article-208929/tobacco]</ref> In consumption it most commonly appears in the forms of [[Tobacco smoking|smoking]], [[Chewing tobacco|chewing]], [[snuff]]ing, or [[dipping tobacco]], or [[snus]]. Tobacco has long been in use as an [[entheogen]] in the Americas. However, upon the arrival of [[Europe]]ans in North America, it quickly became popularized as a trade item and as a recreational drug. This popularization led to the development of the southern economy of the [[United States]] until it gave way to cotton. Following the [[American Civil War]], a change in demand and a change in labor force allowed for the development of the [[cigarette]]. This new product quickly led to the growth of tobacco companies, until the scientific controversy of the mid-1900s.
[[File:basma-tobacco-drying.jpg| thumb |Basma tobacco leaves drying in the sun at [[Pomak]] village in [[Xanthi, Greece]]]]


'''Tobacco''' is the common name of several plants in the genus ''[[Nicotiana]]'' of the family [[Solanaceae]], and the general term for any product prepared from the [[curing of tobacco|cured]] leaves of these plants. [[Nicotiana#Species|More than 70 species]] of tobacco are known, but the chief commercial crop is [[Nicotiana tabacum|''N. tabacum'']]. The more potent variant [[Nicotiana rustica|''N. rustica'']] is also used in some countries.
There are many species of tobacco, which are all encompassed by the plant genus ''Nicotiana''. The word ''nicotiana'' (as well as ''[[nicotine]]'') was named in honor of [[Jean Nicot]], French ambassador to Portugal, who in 1559 sent it as a medicine to the court of [[Catherine de Medici]].<ref>colonia 13 509 [http://www.tc.columbia.edu/centers/cifas/drugsandsociety/background/chronologydruguse.html Heading: 1550–1575 Tobacco, Europe.]</ref>


Dried tobacco leaves are mainly used for [[Tobacco smoking|smoking]] in [[cigarette]]s and [[cigar]]s, as well as [[pipe smoking|pipes]] and [[Mu'assel|shishas]]. They can also be consumed as [[Snuff (tobacco)|snuff]], [[chewing tobacco]], [[dipping tobacco]], and [[snus]].
<!-- CULTURAL IMPACT GOES HERE IN A NEW PARAGRAPH WHEN COMPLETE -->Because of the addictive properties of nicotine, [[Physiological tolerance|tolerance]] and [[Chemical dependency|dependence]] develop. Absorption quantity, frequency, and speed of tobacco consumption are believed to be directly related to biological strength of nicotine dependence, [[Substance use disorder|addiction]], and tolerance.<ref>{{cite web|url=http://www.tobaccofacts.org/tob_truth/soaddictive.html|title=Tobacco Facts - Why is Tobacco So Addictive?|publisher=Tobaccofacts.org|date=|accessdate=2008-09-18}}</ref><ref>{{cite web|url=http://www.stanford.edu/group/SICD/PhilipMorris/pmorris.html|title=Philip Morris Information Sheet|publisher=Stanford.edu|date=|accessdate=2008-09-18}}</ref> The usage of tobacco is an activity that is practiced by some 1.1&nbsp;billion people, and up to 1/3 of the adult population.<ref name="Gilman26">Saner L. Gilman and Zhou Xun, "Introduction" in ''Smoke''; p. 26</ref> The [[World Health Organization]] reports it to be the leading preventable cause of death worldwide and estimates that it currently causes 5.4 million deaths per year.<ref>{{cite journal|url=http://www.who.int/tobacco/mpower/mpower_report_forward_summary_2008.pdf|title=WHO Report on the global tobacco epidemic, 2008 (foreword and summary)|publisher=[[World Health Organization]]|year=2008|format=PDF|pages=8|quote=Tobacco is the single most preventable cause of death in the world today.}}</ref> Rates of smoking have leveled off or declined in [[developed countries]], however they continue to rise in [[developing countries]].<!-- ECONOMIC IMPACT GOES HERE IN ANOTHER PARAGRAPH WHEN COMPLETE -->


Tobacco contains the highly addictive [[stimulant]] alkaloid [[nicotine]] as well as [[harmala alkaloid]]s.<ref>{{Cite encyclopedia |title=Tobacco |encyclopedia=The Encyclopaedia of Psychoactive Substances |publisher=[[Little, Brown and Company]] |last1=Rudgley |first1=Richard |author-link=Richard Rudgley |location=London |url=https://www.biopsychiatry.com/tobacco/ |access-date=November 26, 2017 |date=1998 |isbn=978-0-316-64347-4 |oclc=39129000 |archive-url=https://web.archive.org/web/20220927041956/https://www.biopsychiatry.com/tobacco/ |archive-date=September 27, 2022 }}</ref> Tobacco use is a cause or risk factor for many deadly diseases, especially those affecting the [[heart]], [[liver]], and [[lung]]s<ref>{{cite web |last1=CDC |title=What Are the Risk Factors for Lung Cancer? |date=August 2, 2023 |url=https://www.cdc.gov/cancer/lung/basic_info/risk_factors.htm#:~:text=Cigarette%20smoking%20is%20the%20number,of%20more%20than%207%2C000%20chemicals. |access-date=31 March 2024}}</ref> as well as [[Health effects of tobacco#Cancer|many cancers]]. In 2008, the [[World Health Organization]] named tobacco use as the world's single greatest preventable cause of death.<ref name="who 2008 mpower">{{Cite book |date=2008 |title=WHO Report on the Global Tobacco Epidemic 2008 : The MPOWER Package. |url=https://apps.who.int/iris/bitstream/handle/10665/43818/9789241596282_eng.pdf?sequence=1&isAllowed=y |archive-url=https://web.archive.org/web/20220121162003/https://apps.who.int/iris/bitstream/handle/10665/43818/9789241596282_eng.pdf?sequence=1&isAllowed=y |archive-date=January 21, 2022 |access-date=October 6, 2022 |publisher=[[World Health Organization]] |pages=6, 8, 20 |isbn=978-92-4-068311-2 |oclc=476167599 |quote=Tobacco is the single most preventable cause of death in the world today.}}</ref>
Tobacco is cultivated similarly to other agricultural products. [[Seed]]s are sown in [[cold frame]]s or hotbeds to prevent attacks from insects, and then transplanted into the fields. Tobacco is an annual crop, which is usually harvested mechanically or by hand. After harvest, tobacco is stored for curing, which allows for the slow [[oxidation]] and degradation of [[carotenoid]]s. This allows for the agricultural product to take on properties that are usually attributed to the "smoothness" of the smoke. Following this, tobacco is packed into its various forms of consumption, which include smoking, chewing, sniffing, and so on.


[[File:Fumo Mercado Minas Gerais.jpg|thumb|In Minas Gerais, Brazil]]
==Etymology==


==Etymology==
The Spanish word "''tabaco''" <!-- notice for spellcheckers: 'tabaco' is the correct spelling of the Spanish word -->is thought to have its origin in [[Arawakan]] language, particularly, in the [[Taino]] language of the [[Caribbean]]. In Taino, it was said to refer either to a roll of tobacco leaves (according to [[Bartolome de Las Casas]], 1552), or to the ''[[tabago]]'', a kind of Y-shaped pipe for sniffing tobacco smoke (according to Oviedo; with the leaves themselves being referred to as ''cohiba'').<ref>{{cite web|url=http://wais.stanford.edu/Cuba/cuba_ColumbusDiscoversCuba(110503).html|title=World Association of International Studies, Stanford University}}</ref>
The English word 'tobacco' originates from the Spanish word ''tabaco''.<ref name="Ernst">{{Cite journal |last=Ernst |first=A. |date=1889 |title=On the etymology of the word tobacco |url=https://zenodo.org/record/1448956 |journal=[[American Anthropologist]] |volume=A2 |issue=2 |pages=133–142 |doi=10.1525/aa.1889.2.2.02a00020 |doi-access=free|issn = 0002-7294 }}</ref> The precise origin of this word is disputed, but it is generally thought to have derived, at least in part, from [[Taíno language|Taíno]], the [[Arawakan]] language of the [[Caribbean]]. In Taíno, it was said to mean either a roll of tobacco leaves (according to [[Bartolomé de las Casas]], 1552), or to ''tabago'', a kind of L-shaped pipe used for sniffing tobacco smoke (according to Oviedo, with the leaves themselves being referred to as ''cohiba'').<ref>{{Cite web |last=Hilton |first=Ronald |author-link=Ronald Hilton |title=Christopher Columbus discovers Cuba |date=April 3, 2011 |url=http://wais.stanford.edu/Cuba/cuba_ColumbusDiscoversCuba(110503).html |url-status=dead |archive-url=https://web.archive.org/web/20110901214953/http://wais.stanford.edu/Cuba/cuba_ColumbusDiscoversCuba(110503).html |archive-date=September 1, 2011 |series=[[World Association of International Studies]] |publisher=[[Stanford University]]}}</ref><ref name=Ernst/>


However, perhaps coincidentally, similar words in Spanish, Portuguese and Italian were used from 1410 for certain medicinal [[herb]]s. These probably derived from the Arabic {{lang|ar|طُبّاق|rtl=yes}} {{transliteration|ar|ṭubbāq}} (also {{lang|ar|طُباق|rtl=yes}} {{transliteration|ar|ṭubāq}}), a word reportedly dating to the ninth century, referring to various herbs.<ref>{{Cite encyclopedia |title=طُباق |encyclopedia=[[Arabic–English Lexicon|An Arabic-English Lexicon: Derived From the Best and the Most Copious Eastern Sources]] |publisher=[[Williams and Norgate]] |location=London |url=http://ejtaal.net/aa/ |last=Lane |first=Edward William |date=1863 |author-link=Edward William Lane |volume=I, Book 5 |page=1827 |isbn=978-0-342-25192-6 |oclc=1299308839 |archive-url=https://web.archive.org/web/20160622063627/http://ejtaal.net/aa/#hw4=h660,ll=1916,ls=5,la=2636,sg=645,ha=438,pr=97,vi=240,mgf=549,mr=381,mn=839,aan=360,kz=1457,ulq=1133,uqa=265,uqw=990,umr=652,ums=546,umj=489,uqq=210,bdw=549,amr=392,asb=593,auh=947,dhq=338,mht=549,msb=147,tla=68,amj=481,ens=1,mis=1311 |archive-date=June 22, 2016 |issue=5 |access-date=June 21, 2016 |url-status=live }}</ref><ref>The word {{transliteration|ar|ṭubāq}} no longer refers to various herbs, but has come to refer, in some dialects, specifically to tobacco. ''See'' {{Cite encyclopedia |title=طُباق |encyclopedia=A Dictionary of Modern Written Arabic |publisher=[[Harrassowitz Verlag|Harrassowitz]] |location=Wiesbaden |url=http://ejtaal.net/aa/ |last=Wehr |first=Hans |date=1979 |author-link=Hans Wehr |editor-last=Cowan |editor-first=J Milton |editor-link=J Milton Cowan |edition=4th |page=647 |isbn=978-3-447-02002-2 |oclc=759999696 |archive-url=https://web.archive.org/web/20160622063627/http://ejtaal.net/aa/#hw4=660,ll=h1913,ls=h5,la=h2636,sg=h645,ha=h438,pr=h97,vi=h240,mgf=h549,mr=h381,mn=h839,aan=h360,kz=h1457,ulq=h1133,uqa=h265,uqw=h990,umr=h652,ums=h546,umj=h489,uqq=h210,bdw=550,amr=392,asb=593,auh=947,dhq=338,mht=549,msb=147,tla=68,amj=481,ens=1,mis=1311 |archive-date=June 22, 2016 |url-status=bot: unknown |access-date=June 21, 2016 }}</ref>
However, similar words in Spanish and Italian were commonly used from 1410 to define medicinal [[herb]]s, originating from the [[arabic language|Arabic]] طبق ''tabbaq'', a word reportedly dating to the 9th century, as the name of various herbs.<ref>{{cite web|url=http://www.etymonline.com/index.php?term=tobacco|title=Online Etymological Dictionary}}</ref>


==History==
==History==
{{Refimprove|date=May 2008}}
{{Main|History of tobacco}}
{{Main|History of tobacco}}
{{See also|History of commercial tobacco in the United States}}
{{See also|History of commercial tobacco in the United States}}
[[File:William Michael Harnett (American, 1848-1892). Still Life with Three Castles Tobacco, 1880.jpg|thumbnail|right|[[William Michael Harnett]] (American, 1848–1892), ''Still Life with Three Castles Tobacco'', 1880, [[Brooklyn Museum]]]]
===Early developments===


===Cultural significance===
Tobacco had already long been used in the Americas when European settlers arrived and introduced the practice to Europe, where it became popular. At high doses, tobacco can become [[Psychedelics, dissociatives and deliriants|hallucinogenic]];{{Citation needed|date=October 2007}} accordingly, Native Americans never used the drug [[recreational drug|recreationally]]. Instead, it was often consumed as an [[entheogen]]; among some tribes, this was done only by experienced [[Shamanism|shamans]] or [[medicine man|medicine men]]. {{Citation needed|date=May 2008}} Eastern North American tribes would carry large amounts of tobacco in pouches as a readily accepted trade item, and would often smoke it in [[Peace pipe|pipes]], either in defined ceremonies that were considered sacred, or to seal a bargain,<ref>eg. Heckewelder, ''History, Manners and Customs of the Indian Nations who Once Inhabited Pennsylvania'', p. 149 ff.</ref> and they would smoke it at such occasions in all stages of life, even in childhood.<ref>"They smoke with excessive eagerness&nbsp;... men, women, girls and boys, all find their keenest pleasure in this way." - Dièreville describing the [[Mi'kmaq]], c. 1699 in ''Port Royal''.</ref> It is believed that tobacco is a gift from the Creator and that the exhaled tobacco smoke carries one's thoughts and prayers to [[heaven]].<ref>
According to [[Iroquois mythology]], tobacco [[Origin myth|first grew]] out of Earth Woman's head after she [[Maternal death|died giving birth]] to her [[Twin|twin sons]], [[Hahgwehdiyu|Sapling and Flint]].<ref>{{Cite web|last=Day|first=Ashley|date=November 20, 2023|title=''3 Sisters to Invite to Thanksgiving''|url=https://www.foodandwine.com/the-three-sisters-8404587|publisher=[[Food & Wine]]}}</ref>
''Tobacco: A Study of Its Consumption in the United States'', Jack Jacob Gottsegen, 1940, p. 107.</ref>

[[File:A Smoking Club.jpeg|thumb|right|250px|An Illustration from [[Frederick William Fairholt]]'s ''Tobacco, its History and Association'', 1859.]]
===Traditional use===
[[File:Chute tobacco.JPG|thumb|The earliest depiction of a European man smoking, from ''Tobacco'' by [[Anthony Chute]], 1595]]
[[File:Rajput (Jodhpur) (8411728143).jpg|thumb|An [[Indian people|Indian]] man smoking tobacco through a [[hookah]], [[Rajasthan, India]]]]
Tobacco has long been used in the Americas, with some cultivation sites in Mexico dating back to 1400–1000 BC.<ref>Goodman, Jordan. ''Tobacco in History and Culture: An Encyclopedia'' (Detroit: Thomson Gale, 2005).</ref> Many Native American tribes traditionally grow and use tobacco.<ref name=leonard>{{cite book
|last=Leonard
|first=Jonathan Norton
|author-link=
|date=1970
|title=Recipes, Latin American cooking
|url=https://books.google.com/books?id=J8SLxAEACAAJ
|location=
|publisher=Time-Life International (Nederlands)
|page= 21
|isbn=978-0-8094-0063-8
}}</ref> Historically, people from the [[Indigenous peoples of the Northeastern Woodlands|Northeast Woodlands cultures]] have carried tobacco in pouches as a readily accepted trade item. It was smoked both socially and [[Ceremonial pipe|ceremonially]], such as to seal a peace treaty or trade agreement.<ref>e.g. Heckewelder, ''History, Manners and Customs of the Indian Nations who Once Inhabited Pennsylvania'', p. 149 ff.</ref><ref>"They smoke with excessive eagerness&nbsp;... men, women, girls and boys, all find their keenest pleasure in this way." – Dièreville describing the [[Mi'kmaq people|Mi'kmaq]], ''circa'' 1699 in ''Port Royal''.</ref> In some Native cultures, tobacco is seen as a gift from the [[Creator deity|Creator]], with the ceremonial tobacco smoke carrying one's thoughts and prayers to the Creator.<ref>{{Ci
te book |last=Gottsegen |first=Jack Jacob |title=Tobacco: A Study of Its Consumption in the United States |date=1940 |publisher=[[Pitman (publisher)|Pitman]] |page=107 |oclc=14728283}}</ref>

Some Native Americans consider tobacco to be a medicine and advocate for its respectful usage, rather than a commercial one.<ref>{{cite journal |id={{ProQuest|204813987}} |last1=Cohen |first1=Ken |title=Native American medicine |journal=Alternative Therapies in Health and Medicine |volume=4 |issue=6 |date=November 1998 |pages=45–57 |pmid=9810067 }}</ref>


===Popularization===
===Popularization===
[[File:A Smoking Club.jpeg|thumb|An illustration from [[Frederick William Fairholt]]'s ''Tobacco, its History and Association'', 1859]]
Following the arrival of the Europeans, tobacco became increasingly popular as a trade item. It fostered the economy for the southern United States until it was replaced by cotton. Following the American civil war, a change in demand and a change in labor force allowed inventor [[James Bonsack]] to create a machine which automated cigarette production.
[[File:KITLV - 26868 - Kleingrothe, C.J. - Medan - Tobacco plant and tobacco leaf, Deli - circa 1905.tif|thumb|Tobacco plant and tobacco leaf from the [[Deli Company|Deli plantations]] in Sumatra, 1905]]
Following the arrival of the Europeans to the Americas, tobacco became increasingly popular as a trade item. [[Francisco Hernández de Toledo]], Spanish chronicler of the Indies, was the first European to bring tobacco seeds to the [[Old World]] in 1559 following orders of King [[Philip II of Spain]]. These seeds were planted in the outskirts of [[Toledo, Spain|Toledo]], more specifically in an area known as "Los Cigarrales" named after the continuous plagues of cicadas (''cigarras'' in Spanish). Before the development of the lighter Virginia and white burley strains of tobacco, the smoke was too harsh to be inhaled. Small quantities were smoked at a time, using a pipe like the ''[[midwakh]]'' or ''[[kiseru]],'' or newly invented waterpipes such as the [[bong]] or the [[hookah]] (see [[Nicotiana rustica#Vietnam|thuốc lào]] for a modern continuance of this practice). Tobacco became so popular that the English colony of Jamestown used it as currency and began exporting it as a cash crop; tobacco is often credited as being the export that saved Virginia from ruin.<ref>{{Cite book|title=The Relentless Revolution: A History of Capitalism|last=Appleby|first=Joyce|publisher=W.W. Norton & Company|year=2010|pages=131}}</ref> While a lucrative product, the growing expansion of tobacco demand was intimately tied to the history of [[slavery]] in the Caribbean. <ref>{{Cite web |title=Tobacco and slavery : a neverending history |url=https://www.medicusmundi.ch/de/advocacy/publikationen/mms-bulletin/fighting-tobacco-in-lmic/kapitel-3/tobacco-and-slavery-a-neverending-history |access-date=2024-07-11 |website=www.medicusmundi.ch |language=de}}</ref>


The alleged benefits of tobacco also contributed to its success. The astronomer [[Thomas Harriot]], who accompanied [[Sir Richard Grenville]] on his 1585 expedition to [[Roanoke Island]], thought that the plant "openeth all the pores and passages of the body" so that the bodies of the natives "are notably preserved in health, and know not many grievous diseases, wherewithal we in England are often times afflicted."<ref>{{Cite report |url=https://www.gutenberg.org/files/4247/4247-h/4247-h.htm |title=A BRIEFE AND TRUE REPORT OF THE NEW FOUND LAND OF VIRGINIA |last=Hariot |first=Thomas |date=1590 |publisher=[[Project Gutenberg]]}}</ref>
This increase in production allowed tremendous growth in the tobacco industry until the scientific revelations of the mid-1900s.

Production of tobacco for smoking, chewing, and snuffing became a major industry in Europe and its colonies by 1700.<ref>Eric Burns, ''The Smoke of the Gods: A Social History of Tobacco'' (2006), A popular history focused on the US.</ref><ref>Jordan Goodman, ''Tobacco in History: The Cultures of Dependence'' (1993), A scholarly history worldwide.</ref>

Tobacco has been a major [[cash crop]] in Cuba and in other parts of the Caribbean since the 18th century. Cuban cigars are world-famous.<ref>Charlotte Cosner, ''The Golden Leaf: How Tobacco Shaped Cuba and the Atlantic World'' (Vanderbilt University Press; 2015)</ref>

In the late 19th century, cigarettes became popular. [[James Bonsack]] invented a machine to automate cigarette production. This increase in production allowed tremendous growth in the [[tobacco industry]] until the health revelations of the late 20th century.<ref>Richard Kluger, ''Ashes to Ashes: America's Hundred-Year Cigarette War'' (1996)</ref><ref>Allan Brandt, ''The Cigarette Century: The Rise, Fall, and Deadly Persistence of the Product That Defined America'' (2007)</ref>


===Contemporary===
===Contemporary===
{{See also|Tobacco control|Tobacco in the United States}}


Following the scientific revelations of the mid-1900s, tobacco became condemned as a health hazard, and eventually became encompassed as a cause for cancer, as well as other respiratory and circulatory diseases. This led to the [[Tobacco Master Settlement Agreement]] (MSA) which settled the lawsuit in exchange for a combination of yearly payments to the states and voluntary restrictions on advertising and marketing of tobacco products.
Following the scientific revelations of the mid-20th century, tobacco was condemned as a health hazard, and eventually became recognized as a cause of cancer, as well as other respiratory and circulatory diseases. In the [[United States]], this led to the adoption of the 1998 [[Tobacco Master Settlement Agreement]], which settled the many lawsuits by the U.S. states in exchange for a combination of yearly payments to the states and voluntary restrictions on advertising and marketing of tobacco products.<ref>{{cite journal |last1=Schroeder |first1=Steven A. |title=Tobacco Control in the Wake of the 1998 Master Settlement Agreement |journal=New England Journal of Medicine |date=15 January 2004 |volume=350 |issue=3 |pages=293–301 |doi=10.1056/NEJMsr031421 |pmid=14715919 |doi-access=free }}</ref>


In the 1970s, [[Brown & Williamson]] cross-bred a strain of tobacco to produce [[Y1 (tobacco)|Y1]]. This strain of tobacco contained an unusually high amount of nicotine, nearly doubling its content from 3.2-3.5% to 6.5%. In the 1990s, this prompted the [[Food and Drug Administration]] (FDA) to use this strain as evidence that [[tobacco industry|tobacco companies]] were intentionally manipulating the nicotine content of [[cigarette]]s.
In the 1970s, [[Brown & Williamson]] cross-bred a strain of tobacco to produce [[Y1 (tobacco)|Y1]], a strain containing an unusually high nicotine content, nearly doubling from 3.2 to 3.5%, to 6.5%. In the 1990s, this prompted the [[Food and Drug Administration]] to allege that [[tobacco industry|tobacco companies]] were intentionally manipulating the nicotine content of [[cigarette]]s.<ref>{{Cite web |title=Interviews – Dr. David Kessler {{!}} Inside The Tobacco Deal {{!}} Frontline {{!}} PBS |url=https://www.pbs.org/wgbh/pages/frontline/shows/settlement/interviews/kessler.html |access-date=2023-04-20 |website=www.pbs.org}}</ref>


The desire of many addicted smokers to quit has led to the development of [[nicotine replacement therapy|tobacco cessation products]].<ref>{{Cite journal|last=Commissioner|first=Office of the|date=September 9, 2020|title=Want to Quit Smoking? FDA-Approved Products Can Help|url=https://www.fda.gov/consumers/consumer-updates/want-quit-smoking-fda-approved-products-can-help|journal=FDA|language=en}}</ref>
In 2003, in response to growth of tobacco use in developing countries, the World Health Organization (WHO)<ref>{{cite web|url=http://www.who.int/fctc/en/index.html|title=WHO &#124; WHO Framework Convention on Tobacco Control (WHO FCTC)|publisher=Who.int|date=|accessdate=2008-09-18}}</ref> successfully rallied 168 countries to sign the Framework Convention on Tobacco Control. The Convention is designed to push for effective legislation and its enforcement in all countries to reduce the harmful effects of tobacco. This led to the development of tobacco cessation products.

In 2003, in response to growth of tobacco use in developing countries, the World Health Organization<ref>{{cite web|url=https://www.who.int/fctc/en/index.html|archive-url=https://web.archive.org/web/20080527122132/http://www.who.int/fctc/en/index.html|url-status=dead|archive-date=May 27, 2008|title=WHO &#124; WHO Framework Convention on Tobacco Control (WHO FCTC)|publisher=Who.int|access-date=September 18, 2008}}</ref> successfully rallied 168 countries to sign the Framework Convention on Tobacco Control. The convention is designed to push for effective legislation and enforcement in all countries to reduce the harmful effects of tobacco.<ref>{{cite web|title=WHO {{!}} WHO Framework Convention on Tobacco Control|url=http://www.who.int/fctc/text_download/en/|access-date=February 17, 2021|publisher=WHO}}</ref> Between 2019 and 2021, concerns about increased COVID-19 health risks due to tobacco consumption facilitated smoking reduction and cessation.<ref>{{cite journal |last1=Yang |first1=Haiyang |last2=Ma |first2=Jingjing |title=How the COVID-19 pandemic impacts tobacco addiction: Changes in smoking behavior and associations with well-being |journal=Addictive Behaviors |date=August 2021 |volume=119 |pages=106917 |doi=10.1016/j.addbeh.2021.106917 |doi-access=free |pmid=33862579 |pmc=9186053 }}</ref>


==Biology==
==Biology==
{{More citations needed section|date=June 2017}}
===Nicotiana===

[[File:Nicotine-2D-skeletal.png|thumb|[[Nicotine]] is the compound responsible for the addictive nature of Tobacco use.]]
===''Nicotiana''===
[[File:Native American tobacco flower.jpg|thumb|Tobacco flower, leaves, and buds]]
{{Main|Nicotiana}}
{{Main|Nicotiana}}
{{See also|List of tobacco diseases}}
{{See also|List of tobacco diseases}}
[[File:Nicotine.svg|thumb|[[Nicotine]] is the compound responsible for the addictive nature of tobacco use.]]
There are many species of tobacco, which are encompassed by the genus of herbs ''Nicotiana''. It is part of the nightshade [[family (biology)|family]] ([[Solanaceae]]) indigenous to [[North America|North]] and [[South America]], [[Australia]], south west [[Africa]] and the [[Oceania|South Pacific]].
[[File:Native American tobacco flower.jpg|thumb|upright|Tobacco (''[[Nicotiana rustica]]'') flower, leaves, and buds]]
Many species of tobacco are in the genus of herbs ''Nicotiana''. It is part of the nightshade [[family (biology)|family]] ([[Solanaceae]]) indigenous to North and South America, Australia, south west Africa, and the [[Oceania|South Pacific]].<ref name="Lewis">{{cite journal|last1=Lewis|first1=Albert|title=Tobacco in New Guinea|journal=The American Anthropologist|date=1931|volume=33|issue=1|pages=134–139|doi=10.1525/aa.1931.33.1.02a00290|doi-access=free}}</ref>


Many plants contain [[nicotine]], a powerful [[neurotoxin]], that is particularly harmful to [[insect]]s. However, tobaccos contain a higher concentration of nicotine than most other plants. Unlike many other Solanaceae, they do not contain [[tropane alkaloid]]s, which are often poisonous to humans and other animals.
Most nightshades contain varying amounts of [[nicotine]], a powerful [[neurotoxin]] to [[insect]]s. However, tobaccos tend to contain a much higher concentration of nicotine than the others. Unlike many other Solanaceae species, they do not contain [[tropane alkaloid]]s, which are often poisonous to humans and other animals.


Despite containing enough nicotine and other compounds such as [[germacrene]] and [[anabasine]] and other [[piperidine]] alkaloids (varying between species) to deter most [[herbivore]]s,<ref>Panter ''et al.'' (1990)</ref> a number of such animals have [[evolution|evolve]]d the ability to feed on ''Nicotiana'' species without being harmed. Nonetheless, tobacco is unpalatable to many species, and therefore some tobacco plants (chiefly [[tree tobacco]], ''N. glauca'') have become established as [[invasive weed]]s in some places.
Despite containing enough nicotine and other compounds such as [[germacrene]] and [[anabasine]] and other [[piperidine]] alkaloids (varying between species) to deter most [[herbivore]]s,<ref>{{Cite journal |last1=Panter |first1=KE |last2=Keeler |first2=RF |last3=Bunch |first3=TD |last4=Callan |first4=RJ |year=1990 |title=Congenital skeletal malformations and cleft palate induced in goats by ingestion of Lupinus, Conium and Nicotiana species |journal=Toxicon |pages=1377–1385 |volume=28 |issue=12 |pmid=2089736|doi=10.1016/0041-0101(90)90154-Y |bibcode=1990Txcn...28.1377P }}</ref> a number of such animals have [[evolution|evolve]]d the ability to feed on ''Nicotiana'' species without being harmed. Nonetheless, tobacco is unpalatable to many species due to its other attributes. For example, although the [[cabbage looper]] is a generalist pest, tobacco's gummosis and trichomes can harm early larvae survival.<ref>{{cite journal |last1=Elsey |first1=K. D. |last2=Rabb |first2=R. L. |title=Biology of the Cabbage Looper on Tobacco In North Carolina1 |journal=Journal of Economic Entomology |date=1 December 1967 |volume=60 |issue=6 |pages=1636–1639 |doi=10.1093/jee/60.6.1636 }}</ref> As a result, some tobacco plants (chiefly ''N. glauca'') have become established as [[invasive weed]]s in some places.


===Types===
===Types===

{{Main|Types of tobacco}}
{{Main|Types of tobacco}}
The types of tobacco include:
* [[Types of tobacco#Aromatic Fire-cured|Aromatic fire-cured]] is cured by smoke from open fires. In the United States, it is grown in northern middle [[Tennessee]], central [[Kentucky]], and [[Virginia]]. Fire-cured tobacco grown in Kentucky and Tennessee is used in some chewing tobaccos, moist snuff, some cigarettes, and as a condiment in pipe tobacco blends. Another fire-cured tobacco is [[Latakia (tobacco)|Latakia]], which is produced from oriental varieties of ''N. tabacum''. The leaves are cured and smoked over smoldering fires of local hardwoods and aromatic shrubs in [[Cyprus]] and [[Syria]].
* [[Types of tobacco#Brightleaf tobacco (Virginia tobacco)|Brightleaf tobacco]] is commonly known as "Virginia tobacco", often regardless of the state where it is planted. Prior to the [[American Civil War]], most tobacco grown in the US was fire-cured dark-leaf. Sometime after the [[War of 1812]], demand for a milder, lighter, more aromatic tobacco arose. [[Ohio]], [[Pennsylvania]] and [[Maryland]] all innovated with milder varieties of the tobacco plant. Farmers discovered that brightleaf tobacco needs thin, starved [[soil]], and those who could not grow other crops found that they could grow tobacco. Confederate soldiers traded it with each other and Union soldiers, and developed quite a taste for it. At the end of the war, the soldiers went home and a national market had developed for the local crop.
* [[Types of tobacco#Broadleaf|Broadleaf]], a dark tobacco varietal family popular for producing enormous, resilient, and thick wrapper leaves.{{cn|date=July 2024}}
* [[Burley (tobacco)|Burley tobacco]] is an air-cured tobacco used predominantly in [[cigarette]] production, but also in pipe tobacco as a balance to Virginias and other leaves high in sugar content. In the U.S., burley tobacco plants are started from pelletized seeds placed in polystyrene trays floated on a bed of fertilized water in March or April.
* [[Cavendish tobacco|Cavendish]] is more a process of curing and a method of cutting tobacco than a type, but is used to thicken flavors from other tobaccos that might lack a body. The processing and the cut are used to bring out the natural sweet taste in the tobacco. Cavendish can be produced from any tobacco type but is usually one of, or a blend of, Kentucky, Virginia and burley and is most commonly used for pipe tobacco.
* [[Criollo tobacco]] is primarily used in the making of [[cigar]]s. It was by most accounts one of the original Cuban tobaccos that emerged around the time of [[Christopher Columbus|Columbus]].
* [[Dokha]] is a tobacco originally grown in [[Iran]], mixed with leaves, bark and herbs for smoking in a ''[[midwakh]]''.
* [[Perique]] was developed in 1824 through the technique of pressure-fermentation of local tobacco by a farmer, Pierre Chenet. Considered the [[truffle]] of [[smoking pipe (tobacco)|pipe]] tobaccos, it is used as a component in many blended pipe tobaccos but is too strong to be smoked pure. At one time the freshly moist Perique was also chewed, but it is no longer sold for this purpose. It is typically blended with pure Virginia to lend spice, strength and coolness to the blend.
* [[Types of tobacco#Shade tobacco|Shade tobacco]] is cultivated in [[Connecticut]] and [[Massachusetts]]. Early Connecticut [[colonist]]s acquired from the Native Americans the habit of smoking tobacco in pipes, and began cultivating the plant commercially, though the [[Puritans]] referred to it as the "evil weed". The [[Connecticut shade tobacco|Connecticut shade]] industry has weathered some major [[Disaster|catastrophes]], including a devastating [[hail]]storm in 1929 and an epidemic of brown spot fungus in 2000, and is in danger of disappearing altogether, given the increase in the value of land.
* [[Turkish tobacco]] is a sun-cured, highly aromatic, small-leafed variety (''[[Nicotiana tabacum]]'') grown in Turkey, Greece, [[Bulgaria]] and [[North Macedonia]]. Originally grown in regions historically part of the [[Ottoman Empire]], it is also known as ‘oriental’. Many of the early brands of cigarettes were made mostly or entirely of Turkish tobacco. Its main use evolved to be included in blends of pipe and especially cigarette tobacco. (A typical American cigarette is a blend of bright Virginia, burley and Turkish.)
* [[Types of tobacco#White Burley|White burley]] air-cured leaf was found to be milder than other types of tobacco. In 1865 George Webb of [[Brown County, Ohio]], planted red [[Burley (tobacco)|burley]] seeds he had purchased and found a few of the seedlings had a whitish, sickly look, which became white burley.
* [[Types of tobacco#Wild tobacco|Wild tobacco]] is native to the southwestern United States, Mexico and parts of South America. Its botanical name is ''Nicotiana rustica''.


===Parasites===
There are a number of types of tobacco including, but are not limited to:
{{Main|List of tobacco diseases}}
* '''[[Types of tobacco#Aromatic Fire-cured|Aromatic fire-cured]]''', it is cured by smoke from open fires. In the United States, it is grown in northern middle Tennessee, central Kentucky and in [[Virginia]]. Fire-cured tobacco grown in [[Kentucky]] and [[Tennessee]] are used in some chewing tobaccos, moist snuff, some cigarettes, and as a condiment in pipe tobacco blends. Another fire-cured tobacco is [[Latakia (tobacco)|Latakia]], which is produced from oriental varieties of ''N. tabacum''. The leaves are cured and smoked over smoldering fires of local hardwoods and aromatic shrubs in [[Cyprus]] and [[Syria]].
[[File:The tobacco beetle (Page 3) BHL41830187.jpg|thumb|right|230px|Illustration with photographs of [[tobacco leaves]] infested by ''[[Lasioderma serricorne]]'' (tobacco beetles), from Runner, G. A., ''The tobacco beetle'' (1919), Bulletin of the U.S. Department of Agriculture, [[Biodiversity Heritage Library]]]]
* '''[[Types of tobacco#Brightleaf tobacco|Brightleaf tobacco]]''', Brightleaf is commonly known as "Virginia tobacco", often regardless of the state in which they are planted. Prior to the [[American Civil War]], most tobacco grown in the US was fire-cured dark-leaf. This type of tobacco was planted in fertile lowlands, used a robust variety of leaf, and was either fire cured or air cured. Most Canadian cigarettes are made from 100% pure Virginia tobacco.<ref>[http://www.imperialtobaccocanada.com/onewebca/sites/IMP_5TUJVZ.nsf/vwPagesWebLive/A372FF0B8584533BC1256EEC00564B2A?opendocument&SID=&DTC=&TMP=2 Imperial Tobacco Canada - Our products]</ref>
* '''[[Burley (tobacco)|Burley tobacco]]''', is an air-cured tobacco used primarily for [[cigarette]] production. In the U.S., burley tobacco plants are started from palletized seeds placed in polystyrene trays floated on a bed of fertilized water in March or April.
* '''[[Cavendish tobacco|Cavendish]]''' is more a process of curing and a method of cutting tobacco than a type. The processing and the cut are used to bring out the natural sweet taste in the tobacco. Cavendish can be produced from any tobacco type, but is usually one of, or a blend of [[Kentucky]], [[Virginia]], and [[Burley (tobacco)|burley]], and is most commonly used for pipe tobacco and cigars.
* '''[[Criollo tobacco]]''' is a type of tobacco, primarily used in the making of [[cigar]]s. It was, by most accounts, one of the original [[Cuba]]n tobaccos that emerged around the time of [[Christopher Columbus|Columbus]].
* '''[[Types of tobacco#Dokham|Dokham]]''', is a tobacco originally grown in [[Iran]], mixed with leaves, bark, and herbs for smoking in a [[midwakh]].
* '''[[Turkish tobacco]]''', is a sun-cured, highly aromatic, small-leafed variety (''[[Nicotiana tabacum]]'') that is grown in [[Turkey]], [[Greece]], [[Bulgaria]], and [[Republic of Macedonia|Macedonia]]. Originally grown in regions historically part of the [[Ottoman Empire]], it is also known as "oriental". Many of the early brands of cigarettes were made mostly or entirely of Turkish tobacco; today, its main use is in blends of pipe and especially cigarette tobacco (a typical American cigarette is a blend of bright Virginia, burley and Turkish).
* '''[[Perique]]''', a farmer called Pierre Chenet is credited with first turning this local tobacco into the Perique in 1824 through the technique of pressure-fermentation. Considered the [[Truffle (fungi)|truffle]] of [[smoking pipe (tobacco)|pipe]] tobaccos, it is used as a component in many blended pipe tobaccos, but is too strong to be smoked pure. At one time, the freshly moist Perique was also chewed, but none is now sold for this purpose. It is typically blended with pure Virginia to lend spice, strength, and coolness to the blend.
* '''[[Types of tobacco#Shade tobacco|Shade tobacco]]''', is cultivated in [[Connecticut]] and [[Massachusetts]]. Early Connecticut [[colonist]]s acquired from the Native Americans the habit of smoking tobacco in pipes, and began cultivating the plant commercially, even though the [[Puritans]] referred to it as the "evil weed". The industry has weathered some major [[catastrophe]]s, including a devastating [[hail]]storm in 1929, and an epidemic of brown spot fungus in 2000, but is now in danger of disappearing altogether, given the value of the land to real estate speculators.
* '''[[Types of tobacco#White Burley|White burley]]''', in 1865, George Webb of [[Brown County, Ohio|Brown County]], [[Ohio]] planted red [[Burley (tobacco)|burley]] seeds he had purchased, and found that a few of the seedlings had a whitish, sickly look. The air-cured leaf was found to be more mild than other types of tobacco.
* '''[[Types of tobacco#Wild Tobacco|Wild tobacco]]''', is native to the southwestern United States, [[Mexico]], and parts of [[South America]]. Its botanical name is ''Nicotiana rustica''.
* '''[[Y1 (tobacco)|Y1]]''' is a strain of tobacco [[cross-breeding|cross-bred]] by [[Brown & Williamson]] in the 1970s to obtain an unusually high [[nicotine]] content. In the 1990s, the United States [[Food and Drug Administration]] (FDA) used it as evidence that [[tobacco industry|tobacco companies]] were intentionally manipulating the nicotine content of [[cigarette]]s.<ref name="pbs">{{cite web|url=http://www.pbs.org/wgbh/pages/frontline/shows/settlement/interviews/kessler.html|title=Inside the Tobacco Deal - interview with David Kessler|publisher=[[PBS]]|year=2008|accessdate=2008-06-11}}</ref>


Tobacco, alongside its [[List of tobacco products|related products]], can be infested by [[Parasitism|parasites]] such as the ''[[Lasioderma serricorne]]'' (tobacco beetle) and the ''[[Ephestia elutella]]'' (tobacco moth), which are the most widespread and damaging parasites to the [[tobacco industry]].<ref name="Ryan 1995">{{cite book |editor-last=Ryan |editor-first=L. |year=1995 |chapter=Introduction |chapter-url=https://books.google.com/books?id=QzUAI2vK3XMC&pg=PA1 |title=Post-harvest Tobacco Infestation Control |location=[[Norwell, Massachusetts]] and [[Dordrecht]], Netherlands |publisher=[[Kluwer Academic Publishers]] |pages=1–4 |doi=10.1007/978-94-017-2723-5_1 |isbn=978-94-017-2723-5 }}</ref> Infestation can range from the tobacco cultivated in the fields to the [[Tobacco leaves|leaves]] used for manufacturing [[cigar]]s, [[cigarillo]]s, [[cigarette]]s, etc.<ref name="Ryan 1995"/> Both the [[larvae]] of ''Lasioderma serricorne'' and [[caterpillar]]s of ''Ephestia elutella'' are considered [[Pest (organism)|pests]].<ref name="Ryan 1995"/>
==Impact==
===Social===
{{Expand section|information expanding the effects of tobacco on cultural practices|date=January 2009}}
Smoking in public was for a long time something reserved for men, and when done by women was sometimes associated with [[promiscuity]].{{Citation needed|date=September 2009}} In Japan during the [[Edo period]], prostitutes and their clients would often approach one another under the guise of offering a smoke, and the same was true for 19th century Europe.<ref name="Screech-Smoke">Timon Screech, "Tobacco in Edo Period Japan" in ''Smoke'', pp. 92-99</ref>


==Production==
Following the [[American Civil War]] the usage of tobacco, primarily in cigarettes, became associated with [[masculinity]] and power, and is an iconic image associated with the stereotypical [[capitalism|capitalist]]. Today, tobacco is often rejected; this has spawned quitting associations and anti-smoking campaigns. [[Bhutan]] is the only country in the world where tobacco sales are illegal.<ref>[http://www.slate.com/id/2112449/ The First Nonsmoking Nation], [[Slate (magazine)|Slate.com]]</ref>
{{More citations needed|date=May 2008}}


===Demographic===
===Cultivation===
{{Main|Cultivation of tobacco}}
[[File:Patch of Tobacco (Nicotiana tabacum ) in a field in Intercourse, Pennsylvania..jpg|thumb|upright|Tobacco plants growing in a field in [[Intercourse, Pennsylvania|Intercourse]], [[Pennsylvania]]]]


Tobacco is cultivated similarly to other agricultural products. [[Seed]]s were at first quickly scattered onto the soil. However, young plants came under increasing attack from [[flea beetle]]s (''Epitrix cucumeris'' or ''E. pubescens''), which caused destruction of half the tobacco crops in United States in 1876. By 1890, successful experiments were conducted that placed the plant in a frame covered by thin cotton fabric. Modern tobacco seeds are sown in [[cold frame]]s or hotbeds, as their [[germination]] is activated by light.<ref>{{cite journal |last1=Garner |first1=W. W. |title=Tobacco Culture |journal=Farmers' Bulletin |date=February 27, 1914 |issue=571 |pages=3–4 |url=https://books.google.com/books?id=_MX4JEAVPi4C&pg=RA21-PA1 |access-date=March 22, 2020 |publisher=United States Department of Agriculture}}</ref> In the United States, tobacco is often fertilized with the mineral [[apatite]], which partially starves the plant of [[Biological role of nitrogen|nitrogen]], to produce a more desired flavor.
{{Main|Prevalence of tobacco consumption}}


After the plants are about {{convert| 8| inch|cm}} tall, they are transplanted into the fields. Farmers used to have to wait for rainy weather to plant.<ref>{{Cite web |last1=Yorktown |first1=Mailing Address: P. O. Box 210 |last2=Us |first2=VA 23690 Phone: 757 898-2410 Contact |title=Tobacco: Colonial Cultivation Methods - Historic Jamestowne Part of Colonial National Historical Park (U.S. National Park Service) |url=https://www.nps.gov/jame/learn/historyculture/tobacco-colonial-cultivation-methods.htm |access-date=2024-02-21 |website=www.nps.gov |language=en}}</ref> A hole is created in the tilled earth with a tobacco peg, either a curved wooden tool or deer antler. After making two holes to the right and left, the planter would move forward two feet, select plants from his/her bag, and repeat. Various mechanical tobacco planters like Bemis, New Idea Setter, and New Holland [[Transplanter]] were invented in the late 19th and 20th centuries to automate the process: making the hole, watering it, guiding the plant in—all in one motion.<ref>{{cite book|last1=van Willigen|first1=John|last2=Eastwood|first2=Susan|title=Tobacco Culture: Farming Kentucky's Burley Belt|date=2015|publisher=University Press of Kentucky|isbn=978-0-8131-4808-3|page=91|url=https://books.google.com/books?id=JIkfBgAAQBAJ|access-date=February 2, 2018}}</ref>
Research is limited mainly to tobacco smoking, which has been studied more extensively than any other form of consumption. As of 2000, smoking is practiced by some 1.22 billion people, of which men are more likely to smoke than women<ref name="HNPGuindonBoisclair13-16">"[[#HNPGuindonBoisclair|Guindon & Boisclair]]" 2004, pp. 13-16.</ref> (however the gender gap declines with age),<ref>''[[#WomenTobaccoChallenges21st|Women and the Tobacco Epidemic: Challenges for the 21st Century]]'' 2001, pp.5-6.</ref><ref>''[[#2001SurgeonGeneralWomen|Surgeon General's Report — Women and Smoking]]'' 2001, p.47.</ref> poor more likely than rich, and people in developing countries or transitional economies are more likely than people in developed countries.<ref name="WHOTobbacoFactSheet">{{Cite web|url=http://www.wpro.who.int/NR/exeres/978BE0FD-AE30-46C6-8F75-1F40AE7B57BC.htm|title=WHO/WPRO-Tobacco|accessdate=2009-01-01|author=|last=|first=|authorlink=|coauthors=|date=|year=2005|month=|work=|publisher=World Health Organization Regional Office for the Western Pacific|location=|pages=|language=|doi=|archiveurl=|archivedate=|quote=}}</ref> As of 2004, the [[World Health Organization]] (WHO) reports that of the 58.8 million deaths to occur globally,<ref>''[[#WHO2004GBD|The Global Burden of Disease 2004 Update]]'' 2008, p.8.</ref> 5.4 million are tobacco-attributed.<ref>''[[#WHO2004GBD|The Global Burden of Disease 2004 Update]]'' 2008, p.23.</ref>


Tobacco is cultivated annually, and can be [[harvest]]ed in several ways. In the oldest method, still used, the entire plant is harvested at once by cutting off the stalk at the ground with a tobacco knife; it is then speared onto sticks, four to six plants a stick, and hung in a curing barn. In the 19th century, bright tobacco began to be harvested by pulling individual leaves off the stalk as they ripened. The leaves ripen from the ground upwards, so a field of tobacco harvested in this manner entails the serial harvest of a number of "primings", beginning with the ''volado'' leaves near the ground, working to the ''seco'' leaves in the middle of the plant, and finishing with the potent ''[[ligero]]'' leaves at the top. Before harvesting, the crop must be ''topped'' when the pink flowers develop. Topping always refers to the removal of the tobacco flower before the leaves are systematically harvested. As the industrial revolution took hold, the harvesting wagons which were used to transport leaves were equipped with man-powered stringers, an apparatus that used twine to attach leaves to a pole. In modern times, large fields are harvested mechanically, although topping the flower and in some cases the plucking of immature leaves is still done by hand.
===Health===


In the U.S., [[North Carolina]] and [[Kentucky]] are the leaders in tobacco production, followed by [[Tennessee]], [[Virginia]], [[Georgia (U.S. state)|Georgia]], [[South Carolina]] and [[Pennsylvania]].<ref>{{Cite web|url=https://quickstats.nass.usda.gov/|title=USDA/NASS QuickStats Ad-hoc Query Tool|website=quickstats.nass.usda.gov|date=2019|access-date=July 1, 2020}}</ref>
{{Main|Health effects of tobacco}}
{{See also|List of additives in cigarettes}}


===Curing===
The risks associated with tobacco use include diseases affecting the heart and lungs, with smoking being a major risk factor for [[myocardial infarction|heart attacks]], [[stroke]]s, [[chronic obstructive pulmonary disease]] (COPD), [[emphysema]], and [[cancer]] (particularly [[lung cancer]], [[Cancer of the larynx|cancers of the larynx and mouth]], and [[pancreatic cancer]]).
{{Main|Curing of tobacco}}
[[File:Tobacco barn.JPG|thumb|Tobacco barn in [[Simsbury, Connecticut]] used for air curing of shade tobacco]]
[[File:Tobacco drying iran.jpg|thumb|Sun-cured tobacco, [[Bastam, West Azerbaijan|Bastam]], [[Iran]]]]


Curing and subsequent aging allow for the slow [[oxidation]] and degradation of [[carotenoid]]s in tobacco leaf. This produces certain compounds in the tobacco leaves and gives a sweet hay, [[tea]], [[rose oil]], or fruity aromatic flavor that contributes to the "smoothness" of the smoke. Starch is converted to sugar, which [[glycation|glycates]] protein, which is oxidized into [[advanced glycation endproduct]]s (AGEs), a [[caramelization]] process that also adds flavor. Inhalation of these AGEs in tobacco smoke contributes to [[atherosclerosis]] and [[cancer]].<ref>{{cite journal|vauthors=Cerami C, Founds H, Nicholl I, Mitsuhashi T, Giordano D, Vanpatten S, Lee A, Al-Abed Y, Vlassara H, Bucala R, Cerami A |title=Tobacco smoke is a source of toxic reactive glycation products|journal=Proceedings of the National Academy of Sciences of the United States of America|volume=94|issue=25|year=1997|pages=13915–20|doi=10.1073/pnas.94.25.13915|pmid=9391127|pmc=28407|bibcode=1997PNAS...9413915C|doi-access=free}}</ref> Levels of AGEs are dependent on the curing method used.
The [[World Health Organization]] estimates that tobacco caused 5.4 million deaths in 2004<ref name="WHO">[http://www.who.int/entity/healthinfo/global_burden_disease/GBD_report_2004update_full.pdf WHO global burden of disease report 2008]</ref> and 100 million deaths over the course of the 20th century.<ref name=WHO2>[http://www.who.int/entity/tobacco/mpower/mpower_report_prevalence_data_2008.pdf WHO Report on the Global Tobacco Epidemic, 2008]</ref> Similarly, the United States [[Centers for Disease Control and Prevention]] describes tobacco use as "the single most important preventable risk to human health in developed countries and an important cause of premature death worldwide."<ref name="fn1">"[http://www.cdc.gov/tobacco/quit_smoking/you_can_quit/nicotine.htm Nicotine: A Powerful Addiction]." Centers for Disease Control and Prevention.</ref>


Tobacco can be cured through several methods, including:
Rates of smoking have leveled off or declined in the developed world. Smoking rates in the United States have dropped by half from 1965 to 2006, falling from 42% to 20.8% in adults.<ref>[http://www.cdc.gov/mmwr/preview/mmwrhtml/mm5644a2.htm#fig Cigarette Smoking Among Adults - United States, 2006<!-- Bot generated title -->]</ref> In the developing world, tobacco consumption is rising by 3.4% per year.<ref>[http://www.wpro.who.int/media_centre/fact_sheets/fs_20020528.htm WHO/WPRO-Smoking Statistics<!-- Bot generated title -->]</ref>
* '''[[Curing of tobacco#Air|Air-cured]]''' tobacco is hung in well-ventilated barns and allowed to dry over a period of four to eight weeks. Air-cured tobacco is low in sugar, which gives the tobacco smoke a light, mild flavor, and high in nicotine. Cigar and burley tobaccos are 'dark' air-cured.<ref>"tobacco curing." The Hutchinson Unabridged Encyclopedia with Atlas and Weather guide. Abington: Helicon, 2010. Credo Reference. Web. September 26, 2012.</ref>
* '''[[Curing of tobacco#Fire|Fire-cured]]''' tobacco is hung in large barns where fires of hardwoods are kept on continuous or intermittent low smoulder, and takes between three days and ten weeks, depending on the process and the tobacco. Fire curing produces a tobacco low in sugar and high in nicotine. Pipe tobacco, chewing tobacco, and snuff are fire-cured.
* '''[[Curing of tobacco#Flue|Flue-cured]]''' tobacco was originally strung onto tobacco sticks, which were hung from tier poles in curing barns (Aus: [[kiln]]s, also traditionally called 'oasts'). These barns have flues run from externally fed fire boxes, heat-curing the tobacco without exposing it to smoke, slowly raising the temperature over the course of the curing. The process generally takes about a week. This method produces cigarette tobacco that is high in sugar and has medium to high levels of nicotine. Most cigarettes incorporate flue-cured tobacco, which produces a milder, more inhalable smoke. It is estimated that 1 tree is cut to flue-cure every 300 cigarettes, resulting in serious environmental consequences.<ref name="who env effects"/>
* '''[[Curing of tobacco#Sun|Sun-cured]]''' tobacco dries uncovered in the sun. This method is used in Turkey, Greece, and other Mediterranean countries to produce oriental tobacco. Sun-cured tobacco is low in sugar and nicotine and is used in cigarettes.


Some tobaccos go through a second stage of curing, known as ''[[Fermentation (food)|fermenting]]'' or ''sweating''.{{cn|date=July 2024}} [[Cavendish Tobacco|Cavendish]] undergoes fermentation pressed in a ''casing'' solution containing sugar and/or flavoring.{{cn|date=July 2024}}
When the market for tobacco reduced in the West, the industry looked to India and China for 'emerging markets'. Dr. [[Sharad Vaidya]], a cancer surgeon worked tirelessly to fight this, through research, advocacy and passion. He successfully raised awareness, introduced it in the curriculum of children and managed to establish legislation banning public smoking, stopping sports sponsorship, sale to those under 21 years of age.


===Global production===
China is the world's largest tobacco market. Considerable progress has been made in eliminating advertising, posting health warnings, and banning smoking from public buildings. Many doctors, however, smoke and neglect to warn their patients that smoking increases their risk for disease. Judith Mackay, a Hong Kong-based physician, has been a relentless and effective campaigner, assisting Chinese health officials in the effort to reduce smoking and its immense health, social, and economic costs. Among her projects is the [http://www.tobaccoatlas.org/ Tobacco Atlas]. Her work caused Time Magazine to name her to its 2007 list of the most influential figures across the globe. In a 2010 talk at the [http://china.usc.edu USC U.S.-China Institute], Mackay summarized the progress that's been made in China and the challenges that remain.<ref>http://china.usc.edu/ShowArticle.aspx?articleID=1991</ref>
[[File:Tobacco production, OWID.svg|thumb|upright=1.6|Tobacco production, 2018<ref>{{cite web |title=Tobacco production |url=https://ourworldindata.org/grapher/tobacco-production |website=Our World in Data |access-date=March 7, 2020}}</ref>]]


===Economic===
====Trends====
[[File:Preparando o tabaco em Balibó.jpg|thumb|Tobacco production in [[Portuguese Timor]] in the 1930s]]
{{Expand section|discussion of the impact on the poor, taxation, and so forth|date=January 2009}}
Production of tobacco leaf increased by 40% between 1971, when 4.2&nbsp;million tons of leaf were produced, and 1997, when 5.9&nbsp;million tons of leaf were produced.<ref name="United Nations 2010">Food and Agriculture Organization of the United Nations. ''Projection of tobacco production, consumption and trade for the year 2010.'' (Rome, 2003).</ref> According to the [[Food and Agriculture Organization]] (FAO) of the United Nations, tobacco leaf production was expected to hit 7.1&nbsp;million tons by 2010. This number is a bit lower than the record-high production of 1992, when 7.5&nbsp;million tons of leaf were produced.<ref name="United Nations 2004">The Food and Agriculture Organization of the United Nations. ''Higher World Tobacco use expected by 2010-growth rates slowing down.'' (Rome, 2004).</ref> The production growth was almost entirely due to increased productivity by developing nations, where production increased by 128%.<ref name="JhaChaloupka2000">{{cite book |editor1=Prabhat Jha |editor2=Frank J. Chaloupka |author1=Rowena Jacobs |display-authors=etal |title=Tobacco Control in Developing Countries |chapter-url=https://books.google.com/books?id=UTO8AAAAIAAJ&q=supply-side |year=2000 |chapter=The Supply-Side Effects Of Tobacco Control Policies |publisher=Oxford University Press |location=New York |isbn=978-0-19-263250-0 |pages=311ff}}</ref> During that same time, production in developed countries actually decreased.<ref name="United Nations 2004"/> China's increase in tobacco production was the single biggest factor in the increase in world production. China's share of the world market increased from 17% in 1971 to 47% in 1997.<ref name="United Nations 2010"/> This growth can be partially explained by the existence of a low import tariff on foreign tobacco entering China. While this tariff was reduced from 66% in 1999 to 10% in 2004,<ref>{{cite journal |last1 = Hu |first1 = T-W |last2 = Mao |first2 = Z |display-authors=etal |year=2006 |title = China at the Crossroads: The Economics of Tobacco and Health |journal = Tobacco Control |volume = 15 |issue = Suppl 1 |pages = i37–i41 |doi=10.1136/tc.2005.014621 |pmc = 2563551 |pmid=16723674}}</ref> it has still led to local Chinese cigarettes being preferred over foreign cigarettes because of their lower cost.
"Much of the disease burden and premature mortality attributable to tobacco use disproportionately affect the poor", and of the 1.22 billion smokers, 1 billion of them live in developing or transitional economies.<ref name="WHOTobbacoFactSheet" />


====Major producers====
In Indonesia, the lowest income group spends 15% of its total expenditures on tobacco. In Egypt, more than 10% of households expediture in low-income homes is on tobacco. The poorest 20% of households in Mexico spend 11% of their income on tobacco.<ref><!--TEMPORARY REF, PRIMARY SOURCE IS UNDERWAY -->MPOWER p. 26</ref>
{| class="wikitable" style="float:right; margin: 0 0 0.5em 1em"
! colspan=3|Top tobacco producers, 2020<ref name="FAOSTAT">{{cite web|title=FAOSTAT|url=http://www.fao.org/faostat/en/#data/QC/visualize|publisher=Food And Agriculture Organization of the United Nations|access-date=May 17, 2020}}</ref>
|-
! Country
! Production ([[tonne]]s)
! <small>Note</small>
|-
| {{flag|China}}||align=right|2,134,000||
|-
| {{flag|India}}||align=right|761,335||
|-
| {{flag|Brazil}}||align=right|702,208||'''F'''
|-
| {{flag|Zimbabwe}}||align=right|203,488||
|-
| {{flag|Indonesia}}||align=right|199,737||'''F'''
|-
| {{flag|United States}}||align=right|176,635||
|-
| {{flag|Mozambique}}||align=right|158,532||'''F'''
|-
| {{flag|Pakistan}}||align=right|132,872||'''F'''
|-
| {{flag|Argentina}}||align=right|109,333||
|-
| {{flag|Malawi}}||align=right|93,613||'''F'''


|- style="background:#ccc;"
==Production==
| {{noflag}}'''World'''||align=right| '''5,886,147'''||'''A'''
{{Refimprove|date=May 2008}}
|-
===Cultivation===
|colspan=5 style="font-size:.7em"|No note = official figure, F = [[Food and Agriculture Organization|FAO]] Estimate, A = Aggregate (may include official, semiofficial or estimates).
|}


Every year, about 5.9&nbsp;million tons of tobacco are produced throughout the world. The top producers of tobacco are China (36.3%), India (12.9%), Brazil (11.9%) and Zimbabwe (3.5%).<ref name="FAOSTAT"/>
{{Main|Cultivation of tobacco}}


====China====
[[File:Nicotiana Tobacco Plants 1909px.jpg|thumb|Tobacco plants growing in a field in [[Intercourse, Pennsylvania|Intercourse]], [[Pennsylvania]]]]
Around the peak of global tobacco production, 20 million rural Chinese households were producing tobacco on 2.1&nbsp;million hectares of land.<ref name="issues in global economy"/> While it is the major crop for millions of Chinese farmers, growing tobacco is not as profitable as cotton or sugarcane, because the Chinese government sets the market price. While this price is guaranteed, it is lower than the natural market price, because of the lack of market risk. To further control tobacco in their borders, China founded a [[State Tobacco Monopoly Administration]] (STMA) in 1982. The STMA controls tobacco production, marketing, imports, and exports, and contributes 12% to the nation's national income.<ref>{{cite web |url=http://www.gov.cn/english/2005-10/03/content_74295.htm |title=People's Republic of China. "''State Tobacco Monopoly Administration'' |publisher=Gov.cn |date=September 15, 2005 |access-date=October 3, 2013 |archive-date=August 10, 2013 |archive-url=https://web.archive.org/web/20130810034314/http://www.gov.cn/english/2005-10/03/content_74295.htm |url-status=dead }}</ref> As noted above, despite the income generated for the state by profits from state-owned tobacco companies and the taxes paid by companies and retailers, China's government has acted to reduce tobacco use.<ref>{{Cite web |date=February 6, 2010 |title=Talking Points, February 3–17, 2010 |url=https://china.usc.edu/talking-points-february-3-17-2010 |archive-url=https://web.archive.org/web/20150407203139/https://china.usc.edu/talking-points-february-3-17-2010 |archive-date=April 7, 2015 |publisher=[[University of Southern California|USC]] U.S.-China Institute}}</ref>


====India====
Tobacco is cultivated similar to other agricultural products. [[Seed]]s were at first quickly scattered onto the soil. However, young plants came under increasing attack from [[flea beetle]]s (''Epitrix cucumeris'' or ''Epitrix pubescens''), which caused destruction of half the tobacco crops in United States in 1876. By 1890 successful experiments were conducted that placed the plant in a frame covered by thin fabric. Today, tobacco is sown in [[cold frame]]s or hotbeds, as their [[germination]] is activated by light.
India's Tobacco Board is headquartered in [[Guntur]] in the state of [[Andhra Pradesh]].<ref>{{cite web|url=http://tobaccoboard.com/ |title=Tobacco Board, Guntur |publisher=Tobaccoboard.com |access-date=April 21, 2014}}</ref> India has 96,865 registered tobacco farmers<ref name="Shoba 2002">Shoba, John and Shailesh Vaite. Tobacco and Poverty: Observations from India and Bangladesh. Canada, 2002.</ref> and many more who are not registered. In 2010, 3,120 tobacco product manufacturing facilities were operating in all of India.<ref>{{cite web|url=http://india.anythingresearch.com/Tobacco-Product-Manufacturing.html|title=Tobacco Manufacturing in India}}</ref> Around 0.25% of India's cultivated land is used for tobacco production.<ref name="issues in global economy"/>


Since 1947, the [[Indian government]] has supported growth in the tobacco industry. India has seven tobacco research centers, located in [[Tamil Nadu]], [[Andhra Pradesh]], [[Punjab, India|Punjab]], [[Bihar]], [[Mysore]], and [[West Bengal]] which houses the core research institute.
In the [[United States]], tobacco is often fertilized with the mineral [[apatite]], which partially starves the plant of [[nitrogen#Biological role|nitrogen]], to produce a more desired flavor. Apatite, however, contains [[radium]], lead 210, and polonium 210 — which are known [[Health effects of tobacco#Radioactive carcinogens|radioactive carcinogens]].


====Brazil====
After the plants have reached relative maturity, they are transplanted into the fields, in which a relatively large hole is created in the tilled earth with a tobacco peg. Various mechanical tobacco planters were invented in the nineteenth and twentieth centuries to automate the process: making the hole, fertilizing it, guiding the plant in — all in one motion.
In Brazil, around 135,000 family farmers cite tobacco production as their main economic activity.<ref name="issues in global economy"/> Tobacco has never exceeded 0.7% of the country's total cultivated area.<ref name="ReferenceB">{{cite book|last1=International Tobacco Growers' Association|title=Tobacco farming: sustainable alternatives? Volume 2|date=n.d.|publisher=ITGA|location=East Sussex|isbn=978-1-872854-02-1|url=http://www.tobaccoleaf.org/UserFiles/file/Why_Grow_Tobacco/tobacco_farming.pdf|access-date=July 5, 2016|archive-date=April 29, 2017|archive-url=https://web.archive.org/web/20170429032528/http://tobaccoleaf.org/UserFiles/file/Why_Grow_Tobacco/tobacco_farming.pdf|url-status=dead}}</ref> In the southern regions of Brazil, Virginia, and Amarelinho, flue-cured tobacco, as well as burley and Galpão Comum air-cured tobacco, are produced. These types of tobacco are used for cigarettes. In the northeast, darker, air- and sun-cured tobacco is grown. These types of tobacco are used for cigars, twists, and dark cigarettes.<ref name="ReferenceB"/> Brazil's government has made attempts to reduce the production of tobacco but has not had a successful systematic antitobacco farming initiative. Brazil's government, however, provides small loans for family farms, including those that grow tobacco, through the ''Programa Nacional de Fortalecimento da Agricultura Familiar''.<ref name="brazil legal employ">{{cite web |title=Report from South America (Brazil) |url=http://legalempowerment.undp.org/pdf/SouthAmerica_report.pdf |publisher=[[Commission on Legal Empowerment of the Poor]] |access-date=October 6, 2022 |archive-url=https://web.archive.org/web/20070609101410/http://legalempowerment.undp.org/pdf/SouthAmerica_report.pdf |archive-date=June 9, 2007 |date=2006 |url-status=dead}}</ref>


[[File:Tobacco field cuba1.jpg|thumb|Tobacco plantation, [[Pinar del Río]], Cuba]]
Tobacco is cultivated annually, and can be [[harvest]]ed in several ways. In the oldest method, the entire plant is harvested at once by cutting off the stalk at the ground with a sickle. In the nineteenth century, bright tobacco began to be harvested by pulling individual leaves off the stalk as they ripened. The leaves ripen from the ground upwards, so a field of tobacco may go through several so-called "pullings," more commonly known as topping (topping always refers to the removal of the tobacco flower before the leaves are systematically removed and, eventually, entirely harvested. As the industrial revolution took hold, harvesting wagons used to transport leaves were equipped with man-powered stringers, an apparatus which used twine to attach leaves to a pole. In modern times, large fields are harvested mechanically or by hand, although topping the flower and in some cases the plucking of immature leaves is still done by hand.


===Curing===
===Problems in production===


====Child labor====
{{Main|Curing of tobacco}}
{{main|Child labor}}
The International Labour Office reported that the most child-laborers work in agriculture, which is one of the most hazardous types of work.<ref name="hrw child labor">{{Cite book |last1=Wurth |first1=Margaret |last2=Buchanan |first2=Jane |date=May 13, 2014 |editor-last=Becker |editor-first=Jo |editor2-last=Ross |editor2-first=James |editor3-last=Olugboji |editor3-first=Babatunde |others=Joe Amon, Zama Coursen-Neff, Arvind Ganesan, Grace Meng |title=Tobacco's Hidden Children Hazardous Child Labor in United States Tobacco Farming |url=https://www.hrw.org/report/2014/05/13/tobaccos-hidden-children/hazardous-child-labor-united-states-tobacco-farming |archive-url=https://web.archive.org/web/20150806091253/https://www.hrw.org/report/2014/05/13/tobaccos-hidden-children/hazardous-child-labor-united-states-tobacco-farming |archive-date=August 6, 2015 |access-date=October 6, 2022 |publisher=[[Human Rights Watch]] |isbn=978-1-62313-134-0 |oclc=881428758}}</ref> The tobacco industry houses some of these working children. Use of children is widespread on farms in Brazil, China, India, Indonesia, Malawi, and Zimbabwe.<ref>{{Cite report |url=https://www.unicef.org/media/84761/file/SOWC-1997.pdf |title=The State of the World's Children 1997 |last=[[UNICEF]] |date=1997 |location=Oxford |isbn=978-0-19-262871-8 |oclc=36286998 |archive-url=https://web.archive.org/web/20210609190750/https://www.unicef.org/media/84761/file/SOWC-1997.pdf |archive-date=June 9, 2021}}</ref><ref>{{Cite report |url=https://ecommons.cornell.edu/bitstream/handle/1813/78394/ChildLaborSweatandToil2.pdf?sequence=1&isAllowed=y |title=By the Sweat and Toil of Children. Volume 2. The Use of Child Labor in U.S. Agricultural Imports & Forced and Bonded Child Labor : A Report to the Committee on Appropriations, U.S. Congress |last1=Jaffe |first1=Maureen E. |last2=Mills |first2=Monica |date=1995 |publisher=International Child Labor Study Group, [[Bureau of International Labor Affairs]], [[United States Department of Labor|Department of Labor]] |location=Washington, D.C. |last3=Rosen |first3=Sonia A. |last4=Shepard |first4=Robert B. |last5=Slavet |first5=Beth |last6=Samet |first6=Andrew J. |archive-url=https://web.archive.org/web/20221006221232/https://ecommons.cornell.edu/bitstream/handle/1813/78394/ChildLaborSweatandToil2.pdf?sequence=1&isAllowed=y |archive-date=October 6, 2022}}</ref><ref>{{Cite report |url=http://www.ilo.org/public/libdoc/ilo/1997/97B09_232_engl.pdf |title=Bitter Harvest, Child Labour in Agriculture |date=1997 |publisher=[[International Labour Organization]] |location=Geneva |archive-url=https://web.archive.org/web/20221006222138/http://www.ilo.org/public/libdoc/ilo/1997/97B09_232_engl.pdf |archive-date=October 6, 2022}}</ref><ref>{{Cite conference |last1=Bosch |first1=Dawie |last2=Gordon |first2=Adele |date=August 27–30, 1996 |title=Child Labour in Commercial Agriculture in Africa (Working paper number 3) |url=https://www.worldcat.org/oclc/36763053 |publisher=[[International Programme on the Elimination of Child Labour]], [[International Labour Organization]] |conference=Subregional technical workshop on child labour in commercial agriculture for selected English-speaking African countries |location=Dar es Salaam, Tanzania |isbn=978-92-2-110485-8 |oclc=36763053}}</ref> While some of these children work with their families on small, family-owned farms, others work on large plantations.
In late 2009, reports were released by the London-based human-rights group [[Plan International]], claiming that child labor was common on Malawi (producer of 1.8% of the world's tobacco<ref name="United Nations 2010"/>) tobacco farms. The organization interviewed 44 teens, who worked full-time on farms during the 2007–08 growing season. The child-laborers complained of low pay and long hours, as well as physical and sexual abuse by their supervisors.<ref name="malawi child">{{Cite web |last=Clacherty |first=Glynis |date=2009 |title=Hard work, long hours and little pay: Research with children working on tobacco farms in Malawi |url=https://resourcecentre.savethechildren.net/pdf/3809.pdf/ |archive-url=https://web.archive.org/web/20221006212811/https://resourcecentre.savethechildren.net/pdf/3809.pdf/ |archive-date=October 6, 2022 |publisher=[[Plan International]], Clacherty & Associates Education and Social Development (Pty) Ltd}}</ref> They also reported experiencing [[green tobacco sickness]], a form of nicotine poisoning. When wet leaves are handled, nicotine from the leaves gets absorbed in the skin and causes nausea, vomiting, and dizziness. Children were exposed to levels of nicotine equivalent to smoking 50 cigarettes, just through direct contact with tobacco leaves.<ref name="malawi child"/> The [[effects of nicotine on human brain development]] in children can permanently alter brain structure and function.<ref name=England2015>{{cite journal |last1=England |first1=Lucinda J. |last2=Bunnell |first2=Rebecca E. |last3=Pechacek |first3=Terry F. |last4=Tong |first4=Van T. |last5=McAfee |first5=Tim A. |title=Nicotine and the Developing Human |journal=American Journal of Preventive Medicine |date=August 2015 |volume=49 |issue=2 |pages=286–293 |doi=10.1016/j.amepre.2015.01.015 |pmc=4594223 |pmid=25794473 }}</ref>


====Economy====
[[File:Tobacco drying iran.jpg|thumb|Sun-cured tobacco, [[Bastam]], [[Iran]].]]
[[File:MRO Cuba Harvest 01.jpg|thumb|Tobacco harvesting, [[Viñales Valley]], Cuba]]
Major tobacco companies have encouraged global tobacco production. [[Altria Group|Philip Morris]], [[British American Tobacco]], and [[Japan Tobacco]] each own or lease tobacco-manufacturing facilities in at least 50 countries and buy crude tobacco leaf from at least 12 more countries.<ref>"International Cigarette Manufacturers," Tobacco Reporter, March 2001</ref> This encouragement, along with government subsidies, has led to a glut in the tobacco market. This surplus has resulted in lower prices, which are devastating to small-scale tobacco farmers. According to the World Bank, between 1985 and 2000, the inflation-adjusted price of tobacco dropped 37%.<ref>{{cite web |title=Golden Leaf, Barren Harvest: The Costs of Tobacco Farming |url=http://www.ash.org.uk/files/documents/ASH_330.pdf |author=The Campaign for Tobacco Free Kids |date=November 2001 |url-status=dead |archive-url=https://web.archive.org/web/20130406112907/http://www.ash.org.uk/files/documents/ASH_330.pdf |archive-date=April 6, 2013}}</ref> Tobacco is the most widely [[smuggling|smuggled]] legal product.<ref name=ICLJTU>{{cite news |title=Tobacco Underground |url=http://www.icij.org/project/tobacco-underground |access-date=November 26, 2012 |newspaper=The International Consortium of Investigative Journalists}}</ref>


====Environment====
Curing and subsequent aging allow for the slow [[oxidation]] and degradation of [[carotenoid]]s in tobacco leaf. This produces certain compounds in the tobacco leaves, and gives a sweet hay, [[tea]], [[rose oil]], or fruity aromatic flavor that contributes to the "smoothness" of the smoke. Starch is converted to sugar, which [[glycation|glycates]] protein, and is oxidized into [[advanced glycation endproduct]]s (AGEs), a [[caramelization]] process that also adds flavor. Inhalation of these AGEs in tobacco smoke contributes to [[atherosclerosis]] and [[cancer]].<ref>{{cite journal|author=Cerami C, Founds H, Nicholl I, Mitsuhashi T, Giordano D, Vanpatten S, Lee A, Al-Abed Y, Vlassara H, Bucala R, Cerami A|title=Tobacco smoke is a source of toxic reactive glycation products|journal=Proceedings of the National Academy of Sciences of the United States of America (Pnas)|volume=94|issue=25|year=1997|pages=13915–20|doi=10.1073/pnas.94.25.13915|pmid=9391127|pmc=28407}}</ref> Levels of AGE's is dependent on the curing method used.
Tobacco production requires the use of large amounts of [[pesticide]]s. Tobacco companies recommend up to 16 separate applications of pesticides just in the period between planting the seeds in greenhouses and transplanting the young plants to the field.<ref name="Taylor, Peter 1994">{{cite book|last=Taylor|first=Peter|title=Smoke Ring: The Politics of Tobacco|publisher=Panos Briefing Paper|location=London|date=September 1994}}</ref> Pesticide use has been worsened by the desire to produce larger crops in less time because of the decreasing market value of tobacco. Pesticides often harm tobacco farmers because they are unaware of the health effects and the proper safety protocol for working with pesticides. These pesticides, as well as fertilizers, end up in the soil, waterways, and the food chain.<ref>{{cite book|title=FAO Yearbook, Production, Volume 48|year=1995}}</ref> Coupled with child labor, pesticides pose an even greater threat. Early exposure to pesticides may increase a child's lifelong cancer risk, as well as harm their nervous and immune systems.<ref>{{Cite book |last=National Research Council (US) Committee on Pesticides in the Diets of Infants and Children |url=https://www.ncbi.nlm.nih.gov/books/NBK236276/ |title=Pesticides in the Diets of Infants and Children |date=1993 |publisher=[[National Academies Press]] |isbn=978-0-309-04875-0 |location=Washington, D.C. |page=341 |chapter=Chapter 8 Estimating the Risks |doi=10.17226/2126 |pmid=25144038 |oclc=42329648}}</ref>


As with all crops, tobacco crops extract nutrients (such as [[phosphorus]], [[nitrogen]], and [[potassium]]) from soil, decreasing its fertility.<ref name=wwf.panda>{{cite web|title=Tobacco Free Initiative: Environmental issues|url=https://www.who.int/tobacco/research/economics/rationale/environment/en/|archive-url=https://web.archive.org/web/20041219191401/http://www.who.int/tobacco/research/economics/rationale/environment/en/|url-status=dead|archive-date=December 19, 2004|author=World Health Organization}}</ref>
Tobacco can be cured through several methods which include but are not limited to:


Furthermore, the wood used to cure tobacco in some places leads to deforestation. While some big tobacco producers such as China and the United States have access to petroleum, coal, and natural gas, which can be used as alternatives to wood, most developing countries still rely on wood in the curing process.<ref name="wwf.panda"/> Brazil alone uses the wood of 60 million trees per year for curing, packaging, and rolling cigarettes.<ref name="Taylor, Peter 1994"/>
* '''[[Curing of tobacco#Air|Air cured]]''' tobacco is hung in well-ventilated barns and allowed to dry over a period of four to eight weeks. Air-cured tobacco is low in sugar, which gives the tobacco smoke a light, sweet flavor, and high in nicotine. Cigar and burley tobaccos are air cured.
* '''[[Curing of tobacco#Fire|Fire cured]]''' tobacco is hung in large barns where fires of hardwoods are kept on continuous or intermittent low smoulder and takes between three days and ten weeks, depending on the process and the tobacco. . Fire curing produces a tobacco low in sugar and high in nicotine. Pipe tobacco, chewing tobacco, and snuff are fire cured.
* '''[[Curing of tobacco#Flue|Flue cured]]''' tobacco was originally strung onto tobacco sticks, which were hung from tier-poles in curing barns (Aus: [[kiln]]s, also traditionally called [http://education.yahoo.com/reference/dictionary/entry/oast Oasts]). These barns have flues which run from externally fed fire boxes, heat-curing the tobacco without exposing it to smoke, slowly raising the temperature over the course of the curing. The process will generally take about a week. This method produces cigarette tobacco that is high in sugar and has medium to high levels of nicotine.
* '''[[Curing of tobacco#Sun|Sun-cured]]''' tobacco dries uncovered in the sun. This method is used in Turkey, Greece and other Mediterranean countries to produce oriental tobacco. Sun-cured tobacco is low in sugar and nicotine and is used in cigarettes.


In 2017 WHO released a study on the environmental effects of tobacco.<ref name="who env effects">{{Cite book |last=World Health Organization |url=https://www.who.int/tobacco/publications/environmental-impact-overview/en/ |title=Tobacco and its Environmental Impact: An Overview |date=2017 |publisher=World Health Organization |isbn=978-92-4-151249-7 |oclc=988541317 |author-link=World Health Organization |archive-url=https://web.archive.org/web/20170531164632/http://www.who.int/tobacco/publications/environmental-impact-overview/en/ |archive-date=May 31, 2017 |url-status=dead}}</ref>
===Consumption===


===Research===
{{See|Tobacco products}}
Several tobacco plants have been used as [[model organism]]s in [[genetics]]. [[Tobacco BY-2 cells]], derived from ''N. tabacum'' [[cultivar]] 'Bright Yellow-2', are among the most important research tools in plant [[cell biology|cytology]].<ref>{{cite journal | author = Ganapathi TR |display-authors=etal | year = 2004 | title = Tobacco (Nicotiana tabacum L.) – A model system for tissue culture interventions and genetic engineering | url = http://nopr.niscair.res.in/bitstream/123456789/7722/1/IJBT%203(2)%20171-184.pdf | journal = Indian Journal of Biotechnology | volume = 3 | pages = 171–184 }}</ref> Tobacco has played a pioneering role in [[Callus (cell biology)|callus]] culture research and the elucidation of the mechanism by which [[kinetin]] works, laying the groundwork for modern agricultural [[biotechnology]]. The first genetically modified plant was produced in 1982, using ''[[Agrobacterium tumefaciens]]'' to create an antibiotic-resistant tobacco plant.<ref name="PNAS">{{cite journal | author = Fraley RT |display-authors=etal | year = 1983 | title = Expression of bacterial genes in plant cells | journal = Proc. Natl. Acad. Sci. U.S.A. | volume = 80 | issue = 15| pages = 4803–4807 | doi = 10.1073/pnas.80.15.4803 |pmid=6308651 | bibcode=1983PNAS...80.4803F| pmc = 384133 |doi-access=free }}</ref> This research laid the groundwork for all [[genetically modified crops]].<ref name=TransgenicScience>{{cite web |url=http://www.cottoncrc.org.au/communities/Cotton_Info/The_Science_behind_Transgenic_cotton |archive-url=https://web.archive.org/web/20120321224120/http://www.cottoncrc.org.au/communities/Cotton_Info/The_Science_behind_Transgenic_cotton |url-status=dead |archive-date=March 21, 2012 |title=Science of Transgenic Cotton |publisher=Cottoncrc.org.au |access-date=October 3, 2013 }}</ref>


===Genetic modification===
Tobacco is consumed in many forms and through a number of different methods. Below are examples including, but not limited to, such forms and usage.
Because of its importance as a research tool, transgenic tobacco was the first genetically modified (GM) crop to be tested in field trials, in the United States and France in 1986; China became the first country in the world to approve commercial planting of a GM crop in 1993, which was tobacco.<ref name="James 1996">{{cite web|last=James|first=Clive|title=Global Review of the Field Testing and Commercialization of Transgenic Plants: 1986 to 1995|url=http://www.isaaa.org/kc/Publications/pdfs/isaaabriefs/Briefs%201.pdf|publisher=The International Service for the Acquisition of Agri-biotech Applications|access-date=July 17, 2010|year=1996}}</ref>


====Field trials====
* '''[[Beedi]]''' are thin, often flavored, south Asian cigarettes made of tobacco wrapped in a tendu leaf, and secured with colored thread at one end.
Many varieties of transgenic tobacco have been intensively tested in field trials. Agronomic traits such as resistance to pathogens (viruses, particularly to the [[tobacco mosaic virus]] (TMV); fungi; bacteria and nematodes); weed management via herbicide tolerance; resistance against insect pests; resistance to drought and cold; and production of useful products such as pharmaceuticals; and use of GM plants for [[bioremediation]], have all been tested in over 400 field trials using tobacco.<ref name=GMOCompass>{{cite web |url=http://www.gmo-compass.org/eng/database/plants/304.tobacco.html |title=Tobacco |publisher=GMO Compass |access-date=October 3, 2013 |url-status=dead |archive-url=https://web.archive.org/web/20131002090217/http://www.gmo-compass.org/eng/database/plants/304.tobacco.html |archive-date=October 2, 2013}}</ref>
* '''[[Chewing tobacco]]''' is one of the oldest ways of consuming tobacco leaves. It is consumed orally, in two forms: through sweetened strands, or in a shredded form. When consuming the long sweetened strands, the tobacco is lightly chewed and compacted into a ball. When consuming the shredded tobacco, small amounts are placed at the bottom lip, between the gum and the teeth, where it is gently compacted, thus it can often be called ''dipping tobacco''. Both methods stimulate the saliva glands, which led to the development of the [[spittoon]].
* '''[[Cigar]]s''' are tightly rolled bundle of dried and fermented tobacco which is ignited so that its smoke may be drawn into the smoker's mouth.
* '''[[Cigarettes]]''' are a product consumed through the inhalation of smoke and manufactured from cured and finely cut tobacco leaves and reconstituted tobacco, often combined with other additives, then rolled or stuffed into a paper-wrapped cylinder.
* '''[[Creamy snuff]]s''' are tobacco paste, consisting of tobacco, clove oil, glycerin, spearmint, menthol, and camphor, and sold in a toothpaste tube. It is marketed mainly to women in [[India]], and is known by the brand names Ipco (made by Asha Industries), Denobac, [[Tona]], [[Ganesh]]. It is locally known as "mishri" in some parts of Maharashtra.
* '''[[Dipping tobacco]]s''' are a form of smokeless tobacco. Dip is occasionally referred to as "chew", and because of this, it is commonly confused with [[chewing tobacco]], which encompasses a wider range of products. A small clump of dip is 'pinched' out of the tin and placed between the lower or upper lip and gums.
* '''[[Gutka]]''' is a preparation of crushed betel nut, tobacco, and sweet or savory flavorings. It is manufactured in India and exported to a few other countries. A mild stimulant, it is sold across India in small, individual-size packets.
* '''[[Hookah]]''' is a single or multi-stemmed (often glass-based) water pipe for smoking. Originally from India, the hookah has gained immense popularity, especially in the Middle East. A hookah operates by water filtration and indirect heat. It can be used for smoking herbal fruits or cannabis.
* '''[[Kreteks]]''' are cigarettes made with a complex blend of tobacco, cloves and a flavoring "sauce". It was first introduced in the [[1880]]s in Kudus, Java, to deliver the medicinal [[eugenol]] of cloves to the lungs.
* '''[[Roll-Your-Own]]''', often called rollies or roll ups, are very popular, particularly in European countries. These are prepared from loose tobacco, cigarette papers and filters all bought separately. They are usually much cheaper to make.
* '''[[Smoking pipe (tobacco)|Pipe smoking]]''' typically consists of a small chamber (the bowl) for the combustion of the tobacco to be smoked and a thin stem (shank) that ends in a mouthpiece (the bit). Shredded pieces of tobacco are placed into the chamber and ignited.
* '''[[Snuff]]''' is a generic term for fine-ground smokeless tobacco products. Originally the term referred only to dry snuff, a fine tan dust popular mainly in the eighteenth century. Snuff powder originated in the UK town of [[Great Harwood]], and was famously ground in the town's monument prior to local distribution and transport further up north to Scotland. There are two major varieties which include European (dry) and American (moist); although American snuff is often referred to as dipping tobacco.
* '''[[Snus]]''' is steam-cured moist powder [[tobacco#snus|tobacco]] product that is not fermented, and does not induce salivation. It is consumed by placing it in the mouth against the gums for an extended period of time. It is a form of [[snuff]] that is used in a manner similar to American [[dipping tobacco]], but does not require regular spitting.
* '''[[Tobacco products#Topical tobacco paste|Topical tobacco paste]]''' is sometimes recommended as a treatment for [[wasp]], [[hornet]], [[fire ant]], [[scorpion]], and [[bee sting]]s.<ref>[http://pubs.caes.uga.edu/caespubs/pubcd/c782-w.html Beverly Sparks, "Stinging and Biting Pests of People"] Extension Entomologist of the University of Georgia College of Agricultural & Environmental Sciences Cooperative Extension Service.</ref> An amount equivalent to the contents of a cigarette is mashed in a cup with about a 0.5 to 1 teaspoon of water to make a paste that is then applied to the affected area.
* '''[[Tobacco water]]''' is a traditional [[organic farming|organic]] [[insecticide]] used in domestic [[gardening]]. Tobacco dust can be used similarly. It is produced by boiling strong tobacco in water, or by steeping the tobacco in water for a longer period. When cooled, the mixture can be applied as a spray, or 'painted' on to the leaves of garden plants, where it will prove deadly to insects.
===Global Production===
====Trends====
Production of tobacco leaf increased by 40% between 1971, during which 4.2 million tons of leaf were produced, and 1997, during which 5.9 million tons of leaf were produced.<ref name="United Nations 2010">Food and Agriculture Organization of the United Nations. "Projection of tobacco production, consumption and trade for the year 2010." Rome, 2003.</ref> According to the Food and Agriculture organization of the UN, tobacco leaf production is expected to hit 7.1 million tons by 2010. This number is a bit lower than the record high production of 1992, during which 7.5 million tons of leaf were produced.<ref name="United Nations 2004">The Food and Agriculture Organization of the United Nations.''Higher World Tobacco use expected by 2010-growth rates slowing down." (Rome, 2004).</ref> The production growth was almost entirely due to increased productivity by developing nations, where production increased by 128%.<ref>Rowena Jacobs, et. al, "The Supply-Side Effects Of Tobacco Control Policies," in Tobacco Control in Developing Countries, Jha and Chaloupka eds., Oxford University Press, 2000.</ref> During that same time period, production in developing countries actually decreased.<ref name="United Nations 2004"/> China’s increase in tobacco production was the single biggest factor in the increase in world production. China’s share of the world market increased from 17% in 1971 to 47% in 1997.<ref name="United Nations 2010"/> This growth can be partially explained by the existence of a high import tariff on foreign tobacco entering China. While this tariff has been reduced from 64% in 1999 to 10% in 2004,<ref>Hu T-W, Mao Z, et al. "China at the Crossroads: The Economics of Tobacco and Health". Tobacco Control. 2006;15:i37–i41.</ref> it still has led to local, Chinese cigarettes being preferred over foreign cigarettes because of their lower cost.


====Production====
Every year 6.7 million tons of tobacco are produced throughout the world. The top producers of tobacco are China (39.6%), India (8.3%), Brazil (7.0%) and the United States (4.6%).<ref>US Census Bureau-Foreign Trade Statistics, (Washington DC; 2005)</ref>
Currently, only the US is producing GM tobacco.<ref name="James 1996" /><ref name=GMOCompass /> The Chinese virus-resistant tobacco was withdrawn from the market in China in 1997.<ref>{{cite journal |vauthors=Conner AJ, Glare TR, Nap JP |date=January 2003 |title=The release of genetically modified crops into the environment. Part II. Overview of ecological risk assessment |journal=Plant J. |volume=33 |issue=1 |pages=19–46 |pmid=12943539 |doi=10.1046/j.0960-7412.2002.001607.x |doi-access=free}}</ref>{{rp|3}} From 2002 to 2010, cigarettes made with GM tobacco with reduced nicotine content were available in the US under the market name Quest.<ref name=GMOCompass /><ref>{{cite web|url=https://www.forbes.com/sites/ritarubin/2017/08/14/if-you-took-the-nicotine-out-of-cigarettes-would-fewer-people-want-to-smoke/|title=If You Took The Nicotine Out Of Cigarettes, Would Fewer People Want To Smoke?|last=Rubin|first=Rita|website=Forbes|language=en|access-date=May 3, 2019}}</ref>


==Consumption==
====Major Producers====
{{Further|Tobacco products}}
=====China=====
{{More citations needed section|date=January 2021}}
Around the peak of global tobacco production there were 20 million rural Chinese households producing tobacco on 2.1 million hectares of land <ref name="ReferenceA">Food and Agriculture Organization of the United Nations. “Issues in the Global Tobacco Economy.”</ref>. While it is the major crop for millions of Chinese farmers, growing tobacco, is not as profitable as cotton or sugar cane. This is because the Chinese government sets the market price. While this price is guaranteed, it is lower than the natural market price, because of the lack of market risk. To further control tobacco in their borders, China founded a State Tobacco Monopoly Administration (STMA) in 1982. STMA control tobacco production, marketing, imports and exports and contributes 12% to the nation's national income <ref>People's Republic of China. "''State Tobacco Monopoly Administration'' <<http://www.gov.cn/english/2005-10/03/content_74295.htm>>.</ref>. As noted above, despite the income generated for the state by profits from state-owned tobacco companies and the taxes paid by companies and retailers, China's government has acted to reduce tobacco use. At the same time, increasing incomes has enabled more people in China to smoke and to consume more cigarettes.<ref>USC U.S.-China Institute, "Talking Points, February 3–17, 2010: http://china.usc.edu/ShowArticle.aspx?articleID=1992</ref>
Tobacco is consumed in many forms and through a number of different methods. Some examples are:


=====Brazil=====
===Enema===
* '''[[Tobacco smoke enema]]s''' were employed by the [[indigenous peoples of the Americas#North America|indigenous peoples of North America]] to stimulate respiration, injecting the smoke with a rectal tube.<ref>{{Citation |last1 = Hurt |first1 = Raymond |last2 = Barry |first2 = J. E. |last3 = Adams |first3 = A. P. |last4 = Fleming |first4 = P. R. |title = The History of Cardiothoracic Surgery from Early Times |publisher = Informa Health Care |page=120 |year = 1996 |isbn = 978-1-85070-681-6 |url=https://books.google.com/books?id=ShLvi_kRQtQC}}</ref><ref>{{Citation |doi = 10.2307/2843888 |last = Nordenskiold |first = Erland |title = The American Indian as an Inventor |jstor = 2843888 |journal = Journal of the Royal Anthropological Institute |volume = 59 |page=277 |year = 1929}}</ref><ref>{{Harvnb|Hurt|Barry|Adams|Fleming|1996|p=120}}</ref><ref>{{Harvnb|Nordenskiold|1929|p=277}}</ref> Later, in the 18th century, Europeans emulated the Americans.<ref>{{cite web |url=https://www.bcmj.org/special-feature/special-feature-tobacco-smoke-enemas |title=Special feature: Tobacco smoke enemas |author=Sterling Haynes, MD |date=December 2012 |work=British Columbia Medical Journal |publisher=Doctors of BC |access-date=March 29, 2019 }}</ref> Tobacco resuscitation kits consisting of a pair of bellows and a tube were provided by the Royal Humane Society of London and placed at various points along the Thames.<ref>{{cite web |url = http://www.rpharms.com/museum-pdfs/21-enemas.pdf |title = Information Sheet:21 Enemas |website = Information Sheets |publisher = Museum of the Royal Pharmaceutical Society, London |access-date=July 26, 2014}}</ref>
In Brazil around 135,000 family farmers cite tobacco production as their main economic activity.<ref name="ReferenceA"/> Tobacco has never exceeded 0.7% of the country’s total cultivated area.<ref name="ReferenceB">International Tobacco Growers’ Association. “Tobacco Farming: Sustainable Alternative.” Volume II East Sussix:</ref> In the southern regions of Brazil, Virginia and Amarelinho flue-cured tobacco as well as Burley and Galpao Comun air-cured tobacco are produced. These types of tobacco are used for cigarettes. In the northeast, darker, air- and sun-cured tobacco is grown. These types of tobacco are used for cigars, twists and dark-cigarettes.<ref name="ReferenceB"/>
Brazil’s government has made attempts to reduce the production of tobacco, but has not had a successful systematic anti-tobacco farming initiative. Brazil’s government, however, provides small loans for family farms, including those which grow tobacco, through the Programa Nacional de Fortalecimiento da Agricultura Familiar (PRONAF).<ref>High Level Commission on Legal Empowerment of the Poor. “Report from South America.” 2006.</ref>


=====India=====
===Nasal administration===
* '''[[Snuff (tobacco)|Snuff]]''' is a ground smokeless tobacco product, inhaled or ‘snuffed’ through the nose. If referring specifically to the orally consumed moist snuff, see [[dipping tobacco]].
India's Tobacco Board is headquartered in [[Guntur]] in the state of [[Andhra Pradesh]].<ref>http://tobaccoboard.com/component/option,com_contact/Itemid,105/lang,english/</ref> India has 96,865 registered tobacco farmers<ref name="Shoba 2002">Shoba, John and Shailesh Vaite. Tobacco and Poverty: Observations from India and Bangladesh. Canada, 2002.</ref> and many more who are not registered. Around 0.25% of India’s cultivated land is used for tobacco production <ref>3. Food and Agriculture Organization of the United Nations. “Issues in the Global Tobacco Economy.”</ref>. Since 1947, the Indian government has supported growth in the tobacco industry. India has seven tobacco research centers that are located in Madras, Andhra Pradesh, Punjab, Bihar, Mysore, West Bengal, and Rajamundry <ref name="Shoba 2002"/>. Rajahmundry houses the core research institute. The government has set up a Central Tobacco Promotion Council, which works to increase exports of Indian tobacco.


===Smoked===
====Problems in Tobacco Production====
* '''[[Beedi]]''' (also known as bidis or biris) are thin, often flavoured cigarettes from India made of tobacco wrapped in a [[Diospyros melanoxylon|tendu]] leaf, and secured with coloured thread at one end.<ref>{{Cite web|last=Tobacco Free Kids|date=2008|title=Bidis: An Overview|url=https://www.tobaccofreekids.org/assets/global/pdfs/en/IW_facts_products_bidis_overview.pdf|access-date=October 27, 2021|website=Tobacco Free Kids}}</ref>
=====Child Labor=====
* '''[[Cigarette]]s''' are a product consumed through inhalation of smoke and manufactured from cured and finely cut tobacco leaves and reconstituted tobacco, often combined with other additives, then rolled into a paper cylinder.
The International Labour Office reported that the most child-laborers work in agriculture, which is one of the most hazardous types of work.<ref name="ReferenceC">ILO. International Hazard Datasheets on Occupations: Field Crop Worker</ref> The tobacco industry houses some of these working children. There is widespread use of children on farms in Argentina, Brazil, China, India, Indonesia, Malawi, the United States and Zimbabwe.<ref>UNICEF, The State of the World’s Children 1997 (Oxford, 1997); US Department of Agriculture By the Sweat and Toil of Children Volume II: The Use of Child Labor in US Agricultural Imports & Forced and Bonded Child Labor (Washington, 1995); ILO Bitter Harvest: Child Labour in Agriculture (Geneva, 1997); ILO Child Labour on Commerical Agriculture in Africa (Geneva 1997)</ref> While some of these children work with their families on small family-owned farms, others work on large plantations.
* '''[[Cigar]]s''' are tightly rolled bundles of dried and fermented tobacco, which are ignited so their smoke may be drawn into the smokers' mouths.
In late 2009 reports were released by the London-based human-rights group Plan International, claiming that child labor was common on Malawi (producer of 1.8% of the world’s tobacco<ref name="United Nations 2010"/>) tobacco farms. The organization interviewed 44 teens, who worked full-time on farms during the 2007-2008 growing season. The child-laborers complained of low pay, long hours as well as physical and sexual abuse by their supervisors.<ref>Plan International. ''"Malawi Child Tobacco Pickers' '50-a-day habit"'' http://plan-international.org/about-plan/resources/media-centre/press-releases/malawi-child-tobacco-pickers-50-a-day-habit/?searchterm=tobacco</ref> They also reported suffering from “green tobacco sickness,” a form of nicotine poisoning. When wet leaves are handled, nicotine from the leaves gets absorbed in the skin and causes nausea, vomiting and dizziness. Children were exposed to 50-cigarettes worth of nicotine through direct contact with tobacco leaves. This level of nicotine in children can permanently alter brain structure and function.<ref name="ReferenceC"/>
* '''[[Dokha]]''' is a middle eastern tobacco with high nicotine levels grown in parts of Oman and Hatta, which is smoked through a thin pipe called a medwakh. It is a form of tobacco which is dried up and ground and contains little to no additives excluding spices, fruits, or flowers to enhance smell and flavor.
* '''[[Heat-not-burn product]]s''' heat rather than burn tobacco to generate an aerosol that contains nicotine.
* '''[[Hookah]]''' is a single- or multistemmed (often glass-based) water pipe for smoking. Hookahs were first used in India and Persia;<ref>American Lung Association. February 2007 [http://www.lungusa2.org/embargo/slati/Trendalert_Waterpipes.pdf An Emerging Deadly Trend: Waterpipe Tobacco Use] {{Webarchive|url=https://web.archive.org/web/20140102171735/http://www.lungusa2.org/embargo/slati/Trendalert_Waterpipes.pdf |date=January 2, 2014 }}</ref> the hookah has gained immense popularity, especially in the Middle East. A hookah operates by water filtration and indirect heat. It can be used for smoking herbal fruits or [[moassel]], a mixture of tobacco, flavouring, and [[honey]] or [[glycerin]].
* '''[[Roll-your-own]]''', often called 'rollies' or 'roll-ups', are relatively popular in some European countries. These are prepared from loose tobacco, cigarette papers, and filters all bought separately. They are usually cheaper to make.
* '''[[Tobacco pipe]]s''' typically consist of a small chamber (the bowl) for the combustion of the tobacco to be smoked and a thin stem (shank) that ends in a mouthpiece (the bit). Shredded pieces of tobacco are placed in the chamber and ignited.


===In the mouth===
Families that farm tobacco often have to make the difficult decision between having their children work or go to school. Unfortunately working often beats education because tobacco farmers, especially in the developing world, cannot make enough money from their crop to survive without the cheap labor that children provide.


Tobacco used in the mouth (buccal ([[Sublabial administration|sublabial]]), [[Sublingual administration|sublingual]]):
=====Economy=====
* '''[[Chewing tobacco]]''' is the oldest way of consuming tobacco leaves. It is consumed orally, in two forms: through sweetened strands ("chew" or "chaw"), or in a shredded form ("dip"). When consuming the long, sweetened strands, the tobacco is lightly chewed and compacted into a ball. When consuming the shredded tobacco, small amounts are placed inside the bottom lip, between the gum and the teeth, where it is gently compacted, thus it is often called dipping tobacco. Both methods stimulate the salivary glands, which led to the development of the [[spittoon]].
The cultivation of tobacco is economically detrimental to the countries that produce it, especially those that are still developing. When resources are put into tobacco production, they are taken away from food production. Large amount of firewood, that could be used domestically for fuel and heating, are instead used for the curing of tobacco.
* '''[[Creamy snuff]]''' is tobacco paste, consisting of tobacco, clove oil, glycerin, spearmint, menthol, and camphor, and sold in a toothpaste tube. It is marketed mainly to women in India and is known by the brand names Ipco (made by Asha Industries), Denobac, Tona, and Ganesh. It is locally known as ''mishri'' in some parts of Maharashtra.
* '''[[Dipping tobacco]]s''' are a form of [[smokeless tobacco]]. Dip is occasionally referred to as "chew", and because of this it is commonly confused with [[chewing tobacco]], which encompasses a wider range of products. A small clump of dip is 'pinched' out of the tin and placed between the lower or upper lip and gums. Some brands, as with snus, are portioned in small, porous pouches for less mess.
* '''[[Gutka]]''' is a preparation of crushed betel nut, tobacco, and sweet or savory flavorings. It is manufactured in India and exported to a few other countries. A mild stimulant, it is sold across India in small, individual-sized packets.
* '''[[Kreteks]]''' are cigarettes made with a complex blend of tobacco, cloves, and a flavoring "sauce". They were first introduced in the 1880s in Kudus, Java, to deliver the medicinal [[eugenol]] of cloves to the lungs.
* '''[[Pituri]]''', a nicotine-containing substance traditionally made from Australian tobacco plants, used by Indigenous Australians for chewing and placed between the lower or upper lip and gums.
* '''[[Snus]]''' is a steam-pasteurized moist powdered tobacco product that is not fermented and induces minimal salivation. It is consumed by placing it (loose or in little pouches) against the upper gums for an extended period of time. It is somewhat similar to dipping tobacco but does not require spitting and is significantly lower in [[Tobacco-specific nitrosamines|TSNA]]s.
* '''Tobacco chewing gum''' A gum containing nicotine or tobacco designed to be chewed.
* '''Tobacco edibles''', often in the form of an infusion or a spice, have gained popularity in recent years.
* '''[[Tobacco water]]''' is a traditional [[organic farming|organic]] [[insecticide]] used in domestic [[gardening]]. Tobacco dust can be used similarly. It is produced by boiling strong tobacco in water, or by steeping the tobacco in water for a longer period. When cooled, the mixture can be applied as a spray, or painted onto the leaves of garden plants, where it kills insects. Tobacco is, however, banned from use as a pesticide in certified organic production by the USDA's [[National Organic Program]].<ref>{{cite web |url=http://www.omri.org/simple-gml-search/results?page=18 |title=Generic Materials Search &#124; Organic Materials Review Institute |publisher=Omri.org |access-date=October 3, 2014 |url-status=dead |archive-url=https://web.archive.org/web/20150723072126/http://www.omri.org/simple-gml-search/results?page=18 |archive-date=July 23, 2015}}</ref>


===Topical===
A large percent of the profits from tobacco production go to large tobacco companies rather than local tobacco farmers. Also many countries have government subsides for tobacco farming, which do not make economic sense.<ref>World Health Organization. Tobacco Epidemic: Much More than a Health Issue.” Geneva: 1997.</ref> Major tobacco companies have encouraged global tobacco production. Philip Morris, British American Tobacco and Japan Tobacco each own or lease tobacco manufacturing facilities in at least 50 countries and buy crude tobacco leaf from at least 12 more countries.<ref>“International Cigarette Manufacturers,” Tobacco Reporter, March 2001</ref> This encouragement, along with government subsidies has led to a glut in the tobacco market. This surplus has resulted in lower prices, which are devastating to small-scale tobacco farmers. According to the World Bank, between 1985 and 2000 the inflation-adjusted price of tobacco dropped 37%.<ref>14. Tobacco Free Kids. “Golden Leaf, Barren Harvest: The Costs of Tobacco Farming.”<< http://tobaccofreekids.org/campaign/global/FCTCreport1.pdf>></ref>
* '''[[Topical tobacco paste]]''' is sometimes used as a treatment for [[wasp]], [[hornet]], [[fire ant]], [[scorpion]], and [[bee sting]]s.<ref>{{cite web |url=http://pubs.caes.uga.edu/caespubs/pubcd/c782-w.html |first=Beverly |last=Sparks |title=Stinging and Biting Pests of People |archive-url=https://web.archive.org/web/20070214061028/http://pubs.caes.uga.edu/caespubs/pubcd/c782-w.html |archive-date=February 14, 2007}} Extension Entomologist of the University of Georgia College of Agricultural & Environmental Sciences Cooperative Extension Service.</ref> An amount equivalent to the contents of a cigarette is mashed in a cup with about a half a teaspoon of water to make a paste that is then applied to the affected area.


==Influence==
=====Environment=====
Tobacco production requires the use of a large amount of pesticides. Tobacco companies recommend up to 16 separate applications of pesticides just in the period between planting the seeds in greenhouses and transplanting the young plans to the field.<ref name="Taylor, Peter 1994">Taylor, Peter, "Smoke Ring: The Politics of Tobacco", Panos Briefing Paper, September 1994, London</ref> Pesticide use has been worsened by the desire to produce bigger crops in less time because of the decreasing market value of tobacco. Pesticides often harm tobacco farmers because they are unaware of the health affects and the proper safety protocol for working with pesticides. These pesticides as well as fertilizers, end of in the soil, the waterway and the food chain.<ref>FAO Yearbook, Production, Volume 48, 1995</ref> Coupled with child labor, pesticides pose an even greater threat. Early exposure to pesticides may increase a child's life long cancer risk as well as harm his or her nervous and immune systems.<ref>National Research Council, 1995, Pesticides in the Diets of Infants and Children, National Academy Press.</ref>


===Social===
Tobacco is a crop that leeches nutrients, such as phosphorus, nitrogen and potassium, from the soil at a rate higher than any other major crop.<ref>World Wildlife Fund. Agriculture and Environment: Tobacco. <http://wwf.panda.org/about_our_earth/agriculture_impacts/tobacco/environmental_impacts/deforestation/></ref> This leads to dependence on fertilizers.
Smoking in public was, for a long time, reserved for men, and smoking by women was sometimes associated with [[promiscuity]]; in Japan, during the [[Edo period]], prostitutes and their clients often approached one another under the guise of offering a smoke. The same was true in 19th-century Europe.{{sfn|Gilman|Zhou|2004|p=[https://books.google.com/books?id=mM5bYb_uVcwC&pg=PA92 92–99]}}


Following the [[American Civil War]], the use of tobacco, primarily in cigars, became associated with [[masculinity]] and power. Modern tobacco use has often been stigmatized; this has spawned quitting associations and antismoking campaigns.<ref>{{cite journal |last1=Durkin |first1=Sarah |last2=Brennan |first2=Emily |last3=Wakefield |first3=Melanie |author-link3=Melanie Wakefield |year=2012 |title=Mass media campaigns to promote smoking cessation among adults: an integrative review |url=http://tobaccocontrol.bmj.com/content/tobaccocontrol/21/2/127.full.pdf |journal=Tobacco Control |volume=21 |issue=2 |pages=127–138 |doi=10.1136/tobaccocontrol-2011-050345 |pmid=22345235 |s2cid=3053297|doi-access=free }}</ref><ref>{{cite journal |author=Mullin Sandra |year=2011 |title=Global anti-smoking campaigns urgently needed |journal=The Lancet |volume=378 |issue=9795 |pages=970–971 |doi=10.1016/s0140-6736(11)61058-1 |pmid=21741699 |s2cid=7532790}}</ref> [[Bhutan]] is the only country in the world where tobacco sales are illegal.<ref>{{cite news |url=https://slate.com/news-and-politics/2005/01/the-first-nonsmoking-nation.html |title=The First Nonsmoking Nation |work=[[Slate (magazine)|Slate.com]] |first=Eric |last=Weiner |date=January 20, 2005 |access-date=October 23, 2019}}</ref> Due to its propensity for causing [[detumescence]] and erectile dysfunction, some studies have described tobacco as an anaphrodisiacal substance.<ref>{{cite journal |pmid=28723353 |year=2015 |last1=Verze |first1=P. |title=The Link Between Cigarette Smoking and Erectile Dysfunction: A Systematic Review |journal=European Urology Focus |volume=1 |issue=1 |pages=39–46 |last2=Margreiter |first2=M. |last3=Esposito |first3=K. |last4=Montorsi |first4=P. |last5=Mulhall |first5=J. |doi=10.1016/j.euf.2015.01.003}}</ref>
Furthermore, the wood for the curing of tobacco, leads to deforestation. While some big tobacco producers such as China and the United States have access to petroleum, coal and natural gas, which can be used as alternatives to wood, most developing countries still rely on wood in the curing process.<ref>World Wildlife Fund. Agriculture and Environment: Tobacco. <http://wwf.panda.org/about_our_earth/agriculture_impacts/tobacco/environmental_impacts/deforestation/></ref> Brazil alone uses the wood of 60 million trees per year for curing, packaging and rolling cigarettes.<ref name="Taylor, Peter 1994"/> Deforestation is a factor in flooding, decreased soil productivity and general climate change.


==Art==
===Religion===
{{Further|Religious views on smoking}}
{{Expand section|date=May 2010}}
===Advertising===
====Christianity====
In [[Christian denomination]]s of the [[conservative holiness movement]], such as the [[Allegheny Wesleyan Methodist Connection]] and [[Evangelical Wesleyan Church]], the use of tobacco and other drugs is prohibited;<ref name="AWMC2014">{{cite book|title=The Discipline of the Allegheny Wesleyan Methodist Connection (Original Allegheny Conference)|year=2014|publisher=[[Allegheny Wesleyan Methodist Connection]]|location=[[Salem, Ohio|Salem]]|language=en}}</ref>{{rp|37}} ¶42 of the 2014 [[Book of Discipline (United Methodist)|Book of Discipline]] of the Allegheny Wesleyan Methodist Connection states:<ref name="AWMC2014" />{{page needed|date=March 2021}}
{{Main|Tobacco advertising}}
{{quotation|In the judgment of The Allegheny Wesleyan Methodist Connection (Original Allegheny Conference), the use of tobacco is a great evil, unbecoming a Christian, a waste of the Lord's money, and a defilement of the body, which should be the temple of the Holy Ghost. We do, therefore, most earnestly require our members to refrain from its cultivation, manufacture, and sale, and to abstain from its use in all forms, for Jesus' sake. We will not receive as members into our churches nor will we ordain or license to preach or to exhort, persons who use, cultivate, manufacture, or sell tobacco. Using tobacco by a member of a church or of the Conference after being received from this date (June 28, 1927) is a violation of the law of the church, and the offending party should be dealt with according to the judiciary rules.<ref name="AWMC2014" />{{rp|44}}}}
Members of [[the Church of Jesus Christ of Latter-day Saints]] (popularly known as [[Mormons]]) adhere to the [[Word of Wisdom]], a religious health code that is interpreted as prohibiting the consumption of tobacco as well as [[alcohol (drug)|alcohol]], coffee, and tea.<ref>{{cite news |last=Stack |first=Peggy Fletcher |author-link=Peggy Fletcher Stack |date=August 31, 2012 |title=It's Official: Coke and Pepsi are OK for Mormons |newspaper=[[Washington Post]] |agency=([[Religion News Service]]) |url=https://articles.washingtonpost.com/2012-08-31/national/35492011_1_drink-caffeine-lds-leaders-mormons |url-status=dead |access-date=September 20, 2013 |archive-url=https://web.archive.org/web/20130327204542/http://articles.washingtonpost.com/2012-08-31/national/35492011_1_drink-caffeine-lds-leaders-mormons |archive-date=March 27, 2013}}.</ref>


====Islam====
Tobacco advertising is the advertising of tobacco products or use (typically cigarette smoking) by the tobacco industry through a variety of media including sponsorship, particularly of sporting events. It is now one of the most highly regulated forms of marketing. Some or all forms of tobacco advertising are banned in many countries.
{{Main|Islamic views on tobacco}}
Most Islamic scholars have condemned tobacco due to its harmful effects on health. The earliest [[fatwa]] (religious opinion) against tobacco use dates from 1602. Most major Islamic sects prohibit its use. While tobacco is not mentioned in the Quran, the Quran does instruct Muslims to live healthy lives.


====Sikhism====
{{Further|Prohibitions in Sikhism}}
[[Sikhism]], a Dharmic religion from India, considers tobacco consumption as a taboo and very bad for health and spirituality. Initiated [[Sikhs]] are never to consume tobacco in any form.<ref>{{Cite web|last=Dhillon|first=Bikramjit Singh|date=n.d.|title=Sikhs and Smoking|url=https://www.sikhs.org/art9.htm}}</ref>


===Demographic===
{{Gallery
{{Main|Prevalence of tobacco consumption}}
|title=
|footer=
|width=150
|lines=3
|File:Belomorkanalsav.jpg|[[Belomorkanal]] - Russian cigarettes
|File:Hans Rudi Erdt -Problem Cigarettes, 1912.jpg|Hans Rudi Erdt: Problem Cigarettes, 1912
|File:FLI 117.jpg|French Painted Mural Advertisement
|File:Fachgeschäft für Tabakwaren.JPG|Tobacco display in Munich
|File:MuradTurksfull1918Life.jpg|Advertisement for "Murad" Turkish cigarettes 1918
|File:EgyptianDeitiesLifeAd.jpg|Advertisement for "Egyptian Deities" cigarettes 1919
}}


Research on tobacco use is limited mainly to smoking, which has been studied more extensively than any other form of consumption. An estimated 1.1&nbsp;billion people, and up to one-third of the adult population, use tobacco in some form.{{sfn|Gilman|Zhou|2004|p=26}} Smoking is more prevalent among men<ref name="HNPGuindonBoisclair13-16">"[[#HNPGuindonBoisclair|Guindon & Boisclair]]" 2004, pp. 13–16.</ref> (however, the gender gap declines with age),{{sfn|Samet & Yoon|2001|p=5-6}}{{sfn|Surgeon General's Report Women and Smoking|2001|p=47}} the poor, and in transitional or [[developing countries]].<ref name="WHOTobaccoFactSheet">{{cite web|url=http://www.wpro.who.int/NR/exeres/978BE0FD-AE30-46C6-8F75-1F40AE7B57BC.htm|title=WHO/WPRO-Tobacco|access-date=January 1, 2009|year=2005|publisher=World Health Organization Regional Office for the Western Pacific|url-status=dead|archive-url=https://web.archive.org/web/20090211215317/http://www.wpro.who.int/NR/exeres/978BE0FD-AE30-46C6-8F75-1F40AE7B57BC.htm|archive-date=February 11, 2009}}</ref> A study published in [[Morbidity and Mortality Weekly Report]] found that in 2019 approximately one in four youths (23.0%) in the U.S. had used a tobacco product during the past 30 days. This represented approximately three in 10 high school students (31.2%) and approximately one in eight middle school students (12.5%).<ref>{{cite journal |last1=Wang |first1=Teresa W. |last2=Gentzke |first2=Andrea S. |last3=Creamer |first3=MeLisa R. |last4=Cullen |first4=Karen A. |last5=Holder-Hayes |first5=Enver |last6=Sawdey |first6=Michael D. |last7=Anic |first7=Gabriella M. |last8=Portnoy |first8=David B. |last9=Hu |first9=Sean |last10=Homa |first10=David M. |last11=Jamal |first11=Ahmed |last12=Neff |first12=Linda J. |title=Tobacco Product Use and Associated Factors Among Middle and High School Students — United States, 2019 |journal=MMWR. Surveillance Summaries |date=6 November 2019 |volume=68 |issue=12 |pages=1–22 |doi=10.15585/mmwr.ss6812a1 |pmid=31805035 |pmc=6903396 |doi-access=free }}</ref>
===Cinema===
*''[[Thank You for Smoking]]''
*''[[The Insider (film)|The Insider]]''


Rates of smoking continue to rise in developing countries, but have leveled off or declined in [[developed countries]].<ref>{{cite web|url=https://www.who.int/mediacentre/factsheets/fs339/en/ |title=Who Fact Sheet: Tobacco |publisher=Who.int |date=July 26, 2013 |access-date=October 3, 2013}}</ref> Smoking rates in the United States have dropped by half from 1965 to 2006, falling from 42% to 20.8% in adults.<ref>{{cite web|url=https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5644a2.htm#fig |title=Cigarette Smoking Among Adults – United States, 2006 |publisher=Cdc.gov |access-date=October 3, 2013}}</ref> In the developing world, tobacco consumption is rising by 3.4% per year.<ref>{{cite web|url=http://www.wpro.who.int/mediacentre/factsheets/fs_20020528/en/ |archive-url=https://web.archive.org/web/20130826030927/http://www.wpro.who.int/mediacentre/factsheets/fs_20020528/en/ |url-status=dead |archive-date=August 26, 2013 |title=WHO/WPRO-Smoking Statistics |publisher=Wpro.who.int |date=May 27, 2002 |access-date=April 21, 2014}}</ref>
==Gallery==

{{Gallery
===Health effects===
|title=
[[File:HarmCausedByDrugsTable.svg|thumb|upright=1.35|Table from the 2010 [[DrugScience]] study ranking various drugs (legal and illegal) based on statements by drug-harm experts. Tobacco was found to be the sixth overall most dangerous drug.<ref name="Nutt_2010">{{cite journal | vauthors = Nutt DJ, King LA, Phillips LD | title = Drug harms in the UK: a multicriteria decision analysis | journal = Lancet | volume = 376 | issue = 9752 | pages = 1558–1565 | date = November 2010 | pmid = 21036393 | doi = 10.1016/S0140-6736(10)61462-6 | s2cid = 5667719 | citeseerx = 10.1.1.690.1283 }}</ref>]]
|footer=
{{Main|Health effects of tobacco|List of cigarette smoke carcinogens|Tobacco packaging warning messages|List of additives in cigarettes}}
|width=115

|lines=4
====Chemicals====
|File:DunhillLightFlake.jpg|Tobacco can also be pressed into plugs and sliced into flakes.
Tobacco smoking harms health because of the toxic chemicals in tobacco smoke, including [[carbon monoxide]], [[cyanide]], and [[carcinogens]], which have been proven to cause heart and lung diseases and cancer.
|File:MyrtlefordVicTobaccoDryingHut.JPG|A historic kiln in [[Myrtleford, Victoria]], Australia.
Thousands of different substances in cigarette smoke, including [[polycyclic aromatic hydrocarbons]] (such as [[benzopyrene]]), [[formaldehyde]], [[cadmium]], [[nickel]], [[arsenic]], [[tobacco-specific nitrosamines]], and [[phenols]] contribute to the harmful effects of smoking.<ref name="tobaccocontrol.bmj.com">{{cite journal|author=Proctor Robert N|year=2012|title=The history of the discovery of the cigarette-lung cancer link: evidentiary traditions, corporate denial, global toll|url=http://tobaccocontrol.bmj.com/content/21/2/87.full.pdf|journal=Tobacco Control|volume=21|issue=2|pages=87–91|doi=10.1136/tobaccocontrol-2011-050338|pmid=22345227|s2cid=2734836|doi-access=free}}</ref>
|File:basma-tobacco-drying.jpg|[[Basma]] tobacco leaves drying in the sun at [[Pomak]] village in [[Xanthi, Greece]].

|File:Tobacco.jpg|''Broadleaf tobacco'' inspected in [[Chatham, Virginia]], United States.
According to the World Health Organization, tobacco is the single greatest cause of preventable death globally.<ref name="who 2008 mpower"/> WHO estimates that tobacco caused 5.4&nbsp;million deaths in 2004<ref name="WHO 2004">{{Cite book |last1=Mathers |first1=Colin |author-link=Colin Mathers |last2=Boerma |first2=Ties |last3=Fat |first3=Doris Ma |date=2008 |title=The Global Burden of Disease : 2004 Update |url=https://apps.who.int/iris/handle/10665/43942 |archive-url=https://web.archive.org/web/20220207114854/https://apps.who.int/iris/bitstream/handle/10665/43942/9789241563710_eng.pdf?sequence=1&isAllowed=y |archive-date=February 7, 2022 |access-date=October 6, 2022 |publisher=[[World Health Organization]] |hdl=10665/43942 |isbn=978-92-4-156371-0 |oclc=264018380}}</ref> and 100 million deaths over the course of the 20th century.<ref name="who 2008 mpower"/> Similarly, the United States [[Centers for Disease Control and Prevention]] describe tobacco use as "the single most important preventable risk to human health in developed countries and an important cause of premature death worldwide."<ref name="fn1">{{cite web |url=https://www.cdc.gov/tobacco/quit_smoking/you_can_quit/nicotine.htm |title=Nicotine: A Powerful Addiction |work=Centers for Disease Control and Prevention |archive-url=https://web.archive.org/web/20090226225821/http://www.cdc.gov/tobacco/quit_smoking/you_can_quit/nicotine.htm |archive-date=February 26, 2009}}</ref> Due to these health consequences, it is estimated that a 10 hectare (approximately 24.7 acre) field of tobacco used for cigarettes causes 30 deaths per year – 10 from lung cancer and 20 from cigarette-induced diseases like cardiac arrest, gangrene, bladder cancer, mouth cancer, etc.<ref>{{cite journal |last1=Proctor |first1=Robert N |title=The history of the discovery of the cigarette–lung cancer link: evidentiary traditions, corporate denial, global toll: Table 1 |journal=Tobacco Control |date=March 2012 |volume=21 |issue=2 |pages=87–91 |doi=10.1136/tobaccocontrol-2011-050338 |pmid=22345227 |doi-access=free }}</ref>
|File:Tobacoo field poland1.jpg|Tobacco field in northern Poland

|File:Tobacco flowers poland1.jpg|Flowers of tobacco plant in northern Poland in September
The harms caused by inhaling tobacco smoke include diseases of the [[heart]] and [[lung]]s, with smoking being a major risk factor for [[myocardial infarction|heart attacks]], [[stroke]]s, [[chronic obstructive pulmonary disease]] (emphysema), and [[cancer]] (particularly cancers of the [[Lung cancer|lungs]], [[Cancer of the larynx|larynx, mouth]], and [[pancreatic cancers|pancreas]]). Cancer is caused by inhaling carcinogenic substances in tobacco smoke.
}}

Inhaling secondhand tobacco smoke (which has been exhaled by a smoker) can cause lung cancer in nonsmoking adults. In the United States, about 3,000 adults die each year due to lung cancer from secondhand smoke exposure. Heart disease caused by secondhand smoke kills around 46,000 nonsmokers every year.<ref>{{Cite web |title=Secondhand Smoke |url=http://betobaccofree.hhs.gov/health-effects/secondhand-smoke/index.html |url-status=deviated |archive-url=https://web.archive.org/web/20140920231625/http://betobaccofree.hhs.gov/health-effects/secondhand-smoke/index.html |archive-date=September 20, 2014 |website=BeTobaccoFree |publisher=[[United States Department of Health and Human Services|Health and Human Services]]}}</ref>

In children, exposure to secondhand tobacco smoke is associated with a higher incidence and severity of respiratory illnesses, middle ear disease, and asthma attacks. Each year in the United States, secondhand smoke exposure causes 24,500 infants to be born with low birthweight, 71,900 preterm births, 202,300 episodes of asthma, and 790,000 health care visits for ear infections.<ref>{{Cite report |url=https://escholarship.org/uc/item/8hk6960q |title=Proposed Identification of Environmental Tobacco Smoke as a Toxic Air Contaminant |last=Air Resources Board |date=June 24, 2005 |publisher=[[California Environmental Protection Agency]] |access-date=October 6, 2022 |archive-url=https://web.archive.org/web/20211127163329/https://escholarship.org/content/qt8hk6960q/qt8hk6960q.pdf?t=krnni4 |archive-date=November 27, 2021}}</ref>

The addictive alkaloid [[nicotine]] is a [[stimulant]], and popularly known as the most characteristic constituent of tobacco. In drug effect preference questionnaires, a rough indicator of addictive potential, nicotine scores almost as highly as opioids.<ref>{{Cite book |url=http://ww1.drugabuse.gov/pdf/monographs/92.pdf |title=Testing for Abuse Liability of Drugs in Humans |publisher=[[National Institute on Drug Abuse]], [[United States Department of Health and Human Services|Health and Human Services]] |year=1989 |editor-last=Fischman |editor-first=Marian W. |editor-link=Marian Fischman |location=Rockville, MD |page=79 |id=NIDA Research Monograph No. 92 |editor-last2=Mello |editor-first2=Nancy K. |archive-url=https://web.archive.org/web/20161222041641/http://ww1.drugabuse.gov/pdf/monographs/92.pdf |archive-date=December 22, 2016 |url-status=dead}}</ref> Users typically develop [[Physiological tolerance|tolerance]] and [[Chemical dependency|dependence]].<ref>{{cite web |url=http://www.tobaccofacts.org/tob_truth/soaddictive.html |title=Tobacco Facts – Why is Tobacco So Addictive? |publisher=Tobaccofacts.org |access-date=September 18, 2008 |url-status=dead |archive-url=https://web.archive.org/web/20070314185950/http://www.tobaccofacts.org/tob_truth/soaddictive.html |archive-date=March 14, 2007}}</ref><ref>{{cite web |url=http://www.stanford.edu/group/SICD/PhilipMorris/pmorris.html |title=Philip Morris Information Sheet |publisher=[[Stanford University]] |access-date=September 18, 2008 |archive-url=https://web.archive.org/web/20080405204802/http://www.stanford.edu/group/SICD/PhilipMorris/pmorris.html |archive-date=April 5, 2008}}</ref> Nicotine is known to produce [[conditioned place preference]], a sign of psychological enforcement value.<ref>{{cite journal |last1=Le Foll |first1=Bernard |last2=Goldberg |first2=Steven R. |title=Nicotine induces conditioned place preferences over a large range of doses in rats |journal=Psychopharmacology |date=April 2005 |volume=178 |issue=4 |pages=481–492 |doi=10.1007/s00213-004-2021-5 |pmid=15765262 |s2cid=34966899 }}</ref> In one medical study, tobacco's overall harm to user and self was determined at three percent below cocaine, and 13 percent above amphetamines, ranking sixth most harmful of the 20 drugs assessed.<ref>{{cite journal |last1=Nutt |first1=David J |last2=King |first2=Leslie A |last3=Phillips |first3=Lawrence D |title=Drug harms in the UK: a multicriteria decision analysis |journal=The Lancet |date=November 2010 |volume=376 |issue=9752 |pages=1558–1565 |doi=10.1016/S0140-6736(10)61462-6 |citeseerx=10.1.1.690.1283 |pmid=21036393 |s2cid=5667719 }}</ref>

Tobacco also contains 2,3,6-Trimethyl-1,4-naphthoquinone (sometimes called 2,3,6-TQ and TMN) which is a reversible [[monoamine oxidase inhibitor]] of type A and B with a binding affinity somewhat similar to that of [[clorgyline]] and [[deprenyl]]. It is a stronger dopamine releasing agent than nicotine and inhibits dopamine metabolism from its MAOI activity. <ref>{{cite thesis | url=https://repository.nwu.ac.za/handle/10394/590 | title=Smoking and brain dopaminergic neurochemistry | date=March 25, 2024 | publisher=North-West University | type=Thesis | vauthors = McAfee G }}</ref><ref>{{cite web | url=https://pubchem.ncbi.nlm.nih.gov/compound/1_4-Naphthalenedione_-2_3_6-trimethyl | title=1,4-Naphthalenedione, 2,3,6-trimethyl- }}</ref> Tobacco also contains [[Harmine]] and Norharmine which is a reversible MAO-A inhibitor.<ref>{{cite journal | pmc=6592107 | date=2019 | title=Effect of Harmine on Nicotine-Induced Kidney Dysfunction in Male Mice | journal=International Journal of Preventive Medicine | volume=10 | page=97 | doi=10.4103/ijpvm.IJPVM_85_18 | doi-access=free | pmid=31360344 | vauthors = Salahshoor MR, Roshankhah S, Motavalian V, Jalili C }}</ref><ref>{{cite journal | url=https://pubmed.ncbi.nlm.nih.gov/28057462/ | pmid=28057462 | date=2017 | title=Monoamine oxidase inhibitory activity in tobacco particulate matter: Are harman and norharman the only physiologically relevant inhibitors? | journal=Neurotoxicology | volume=59 | pages=22–26 | doi=10.1016/j.neuro.2016.12.010 | vauthors = Truman P, Grounds P, Brennan KA | bibcode=2017NeuTx..59...22T }}</ref><ref>{{cite journal | doi=10.3389/fnmol.2022.925272 | doi-access=free | title=Harmane Potentiates Nicotine Reinforcement Through MAO-A Inhibition at the Dose Related to Cigarette Smoking | date=2022 | journal=Frontiers in Molecular Neuroscience | volume=15 | pmid=35832393 | pmc=9271706 | vauthors = Ding Z, Li X, Chen H, Hou H, Hu Q }}</ref><ref>{{cite journal | url=https://www.jstor.org/stable/4253715 | jstor=4253715 | title=Nicotiana an Hallucinogen? | journal=Economic Botany | date=March 25, 1976 | volume=30 | issue=2 | pages=149–151 | doi=10.1007/BF02862960 | vauthors = Janiger O, De Rios MD | bibcode=1976EcBot..30..149J }}</ref> The MAO-A activity of tobacco alkaloids have been thought to play a role in the addictive qualities of tobacco.<ref>{{cite journal | url=https://jamanetwork.com/journals/jamapsychiatry/fullarticle/1107244 | doi=10.1001/archgenpsychiatry.2011.82 | title=Monoamine Oxidase a Binding in the Prefrontal and Anterior Cingulate Cortices During Acute Withdrawal from Heavy Cigarette Smoking | date=2011 | journal=Archives of General Psychiatry | volume=68 | issue=8 | pages=817–826 | pmid=21810646 | vauthors = Bacher I, Houle S, Xu X, Zawertailo L, Soliman A, Wilson AA, Selby P, George TP, Sacher J, Miler L, Kish SJ, Rusjan P, Meyer JH }}</ref>

====Radioactivity====
[[Polonium-210]] is a radioactive trace contaminant of tobacco, providing additional explanation for the link between smoking and [[bronchial cancer]].<ref name="polonium">{{cite journal|jstor=1712451|title=Polonium-210: A Volatile Radioelement in Cigarettes|journal=Science|volume=143|issue=3603|pages=247–249|last1=Radford|first1=Edward P.|last2=Hunt|first2=Vilma R.|year=1964|doi=10.1126/science.143.3603.247|pmid=14078362|bibcode=1964Sci...143..247R|s2cid=23455633}}</ref>
The radioactive particles build up over time in the lungs and a UCLA study has estimated that the radiation from 25 years of smoking would cause over 120 deaths per thousand smokers.<ref>{{Cite web|url=https://www.uclahealth.org/news/big-tobacco-knew-radioactive-particles-in-cigarettes|title=Big Tobacco knew radioactive particles in cigarettes posed cancer risk but kept quiet|website=www.uclahealth.org}}</ref>

===Economic===
Tobacco makes a significant economic contribution. The global tobacco market in 2010 was estimated at US$760&nbsp;billion, excluding China.<ref>{{Cite web|url=http://www.bat.com/group/sites/UK__9D9KCY.nsf/vwPagesWebLive/DO9DCKFM|title=British American Tobacco – The global market|website=www.bat.com|language=en|access-date=March 15, 2018|archive-date=March 10, 2018|archive-url=https://web.archive.org/web/20180310114510/http://www.bat.com/group/sites/UK__9D9KCY.nsf/vwPagesWebLive/DO9DCKFM|url-status=dead}}</ref> The global revenues from tobacco taxes in 2013–2014 was approximately $269&nbsp;billion.

In China, cigarette manufacturing is one of the few profitable state-owned industries. For example, in 1998 the 1 429 state-owned enterprises in Yunnan province had revenue of [[Renminbi]] (RMB) 69.1&nbsp;billion (US$8.3&nbsp;billion) while 8 cigarette manufacturing plants alone accounted for about 53 percent (or RMB 36.2&nbsp;billion) of total provincial industry sales.<ref name="issues in global economy">{{Cite book |date=2003 |title=Issues in the global tobacco economy : selected case studies. |url=https://www.fao.org/publications/card/en/c/1391c97a-6e5f-59dc-b664-d14e5e401674/ |archive-url=https://web.archive.org/web/20220307151442/https://www.fao.org/3/y4997e/y4997e.pdf |archive-date=March 7, 2022 |access-date=October 6, 2022 |publisher=United Nations [[Food and Agriculture Organization]] |pages=2, 39, 43 |isbn=925105083X |oclc=55056109 |id=Series number 1810-0783}}</ref> The Chinese government also collects tax on tobacco products. Tax revenues from cigarettes increased from 740 to 842&nbsp;billion [[Chinese yuan]] between 2014 and 2016. This generated an additional 101&nbsp;billion Chinese yuan in tax revenues for the government.<ref>{{cite journal |last1=Goodchild |first1=Mark |last2=Zheng |first2=Rong |title=Early assessment of China's 2015 tobacco tax increase |journal=Bulletin of the World Health Organization |date=1 July 2018 |volume=96 |issue=7 |pages=506–512 |doi=10.2471/BLT.17.205989 |doi-broken-date=December 5, 2024 |pmc=6022610 |pmid=29962553 }}</ref>

In India, tobacco generates approximately 20&nbsp;billion [[Indian rupee]]s (US$0.45&nbsp;billion) of income per annum as a result of employment, income and government revenue.<ref>{{Cite web|title=TOBACCO IN INDIA: 4.10 ECONOMIC SIGNIFICANCE OF TOBACCO|url=https://www.fao.org/3/y4997e/y4997e0h.htm|access-date=October 27, 2021|website=Food and Agriculture Organization (FAO).}}</ref>

[[Statistica]] estimates that in the U.S. alone, the tobacco industry has a market of US$121&nbsp;billion,<ref>{{cite web|url=https://www.statista.com/statistics/491709/tobacco-united-states-market-value/|title=Tobacco: U.S. market value 2012–2017 {{!}} Statistic|website=Statista|language=en|access-date=March 15, 2018}}</ref> despite the fact the [[Centers for Disease Control and Prevention|CDC]] reports that US smoking rates are declining steadily.<ref>{{cite web|url=https://www.cdc.gov/tobacco/data_statistics/tables/trends/cig_smoking/index.htm|title=CDC – Trends in Current Cigarette Smoking – Smoking & Tobacco Use|last=Health|first=CDC's Office on Smoking and|website=Smoking and Tobacco Use|language=en-us|access-date=March 15, 2018|archive-url=https://web.archive.org/web/20180307151249/https://www.cdc.gov/tobacco/data_statistics/tables/trends/cig_smoking/index.htm|archive-date=March 7, 2018|url-status=dead}}</ref> In terms of health expenditures, cigarette smoking contributed to more than $225&nbsp;billion (or 11.7%) of annual healthcare spending in the U.S. in 2014.<ref name=":0">{{cite journal |last1=Xu |first1=Xin |last2=Shrestha |first2=Sundar S. |last3=Trivers |first3=Katrina F. |last4=Neff |first4=Linda |last5=Armour |first5=Brian S. |last6=King |first6=Brian A. |title=U.S. healthcare spending attributable to cigarette smoking in 2014 |journal=Preventive Medicine |date=September 2021 |volume=150 |pages=106529 |doi=10.1016/j.ypmed.2021.106529 |pmid=33771566 |pmc=10953804 }}</ref> Smoking-attributable healthcare spending increased more than 30% for Medicaid between 2010 and 2014.<ref name=":0" />

In the US, the decline in the number of smokers, the end of the [[Tobacco Transition Payment Program]] in 2014, and competition from growers in other countries, made tobacco farming economics more challenging.<ref>{{cite news|last1=Bomey|first1=Nathan|title=Thousands of farmers stopped growing tobacco after deregulation payouts|url=https://www.usatoday.com/story/money/2015/09/02/thousands-farmers-stopped-growing-tobacco-after-deregulation-payouts/32115163/|work=USA Today|date=September 2, 2015|language=en}}</ref>

Of the 1.22&nbsp;billion smokers worldwide, 1&nbsp;billion of them live in developing or transitional economies, and much of the disease burden and premature mortality attributable to tobacco use disproportionately affect the poor.<ref name="WHOTobaccoFactSheet" /> While smoking prevalence has declined in many developed countries, it remains high in others, and is increasing among women and in developing countries. Between one-fifth and two-thirds of men in most populations smoke. Women's smoking rates vary more widely but rarely equal male rates.<ref name="greenfacts">{{cite web|title=Tobacco: Active and Passive Smoking|url=http://www.greenfacts.org/en/tobacco/2-tobacco-smoking/1-smoke-tobacco.htm|website=Greenfacts.org|access-date=July 5, 2016}}</ref>

Tobacco users must also spend a significant amount of money on cigarettes to maintain regular use, as tobacco products are often heavily taxed by governments. For example, a pack a day smoker in the state of New York would have to spend around $4,690.25 a year on cigarettes alone.<ref>{{Cite web |title=Cost of Smoking |url=https://tobaccofreelife.org/why-quit-smoking/cost-smoking/ |access-date=July 6, 2022 |website=Tobacco-Free Life |language=en-US}}</ref>

In Indonesia, the lowest income group spends 15% of its total expenditures on tobacco. In Egypt, more than 10% of low-income household expenditure is on tobacco. The poorest 20% of households in Mexico spend 11% of their income on tobacco.<ref name="who 2008 mpower"/>

===Advertising===
{{Main|Nicotine marketing}}
The tobacco industry advertises its products through a variety of media, including sponsorship, particularly of sporting events. Because of the health risks of these products, this is now one of the most highly regulated forms of marketing. Some or all forms of tobacco advertising are banned in many countries.<ref>{{Cite web |last=Products |first=Center for Tobacco |date=January 28, 2022 |title=Advertising and Promotion |url=https://www.fda.gov/tobacco-products/products-guidance-regulations/advertising-and-promotion |access-date=July 6, 2022 |website=FDA |language=en}}</ref>

==Legality==
{{See|Smoking age}}


==See also==
==See also==
* [[List of tobacco related topics]]
* [[Biorefinery|Biorefining of tobacco]]
* [[List of tobacco-related topics]]
* [[Plantation economy]]
* [[Asthma|Research about cure of asthma]] and [[Bronchodilatation]]
* [[Usages of tobacco]]
* [[Smoking cessation]]


==References==
==References==
{{reflist}}
===Notes===
{{Reflist|colwidth=30em}}


===Bibliography===
===Further reading===
* {{cite web |title=Cancer Facts & Figures 2015 |url=http://www.cancer.org/research/cancerfactsstatistics/cancerfactsfigures2015/index |website=American Cancer Society |access-date=February 23, 2015 |ref=ACS2015 |archive-date=January 17, 2017 |archive-url=https://web.archive.org/web/20170117014219/http://www.cancer.org/research/cancerfactsstatistics/cancerfactsfigures2015/index |url-status=dead }}
{{Refbegin}}
* {{cite web|url=http://www1.worldbank.org/tobacco/pdf/Guindon-Past,%20current-%20whole.pdf|title=Past, current and future trends in tobacco use|access-date=January 2, 2008|author1=G. Emmanuel Guindon |author2=David Boisclair |year=2003 |publisher=The International Bank for Reconstruction and Development / The World Bank|location=Washington DC|ref=HNPGuindonBoisclair}}
* <cite id="WHO2008MPOWER">{{Cite web|url=http://www.who.int/entity/tobacco/mpower/mpower_report_full_2008.pdf|format=PDF|title=WHO REPORT on the global TOBACCO epidemic|accessdate=2008-01-01|author=|last=|first=|authorlink=|coauthors=|date=|year=2008|month=|work=|publisher=World Health Organization|location=|pages=|language=|doi=|archiveurl=|archivedate=|quote=}}</cite>
* {{Cite book |last1=Gilman |first1=Sander L. |author-link=Sander Gilman |last2=Zhou |first2=Xun |url=https://archive.org/details/smokeglobalhisto0000unse/mode/2up |title=Smoke : A Global History of Smoking |date=2004 |publisher=[[Reaktion Books]] |isbn=978-1-86189-200-3 |location=London |oclc=56967899 }}
* <cite id="WHO2004GBD">{{Cite web|url=http://www.who.int/entity/healthinfo/global_burden_disease/GBD_report_2004update_full.pdf|format=PDF|title=The Global Burden of Disease 2004 Update|accessdate=2008-01-01|author=|last=|first=|authorlink=|coauthors=|date=|year=2008|month=|work=|publisher=World Health Organization|location=|pages=|language=|doi=|archiveurl=|archivedate=|quote=}}</cite>
* {{Cite book |last1=Mathers |first1=Colin |author-link=Colin Mathers |last2=Boerma |first2=Ties |last3=Fat |first3=Doris Ma |date=2008 |title=The Global Burden of Disease : 2004 Update |url=https://apps.who.int/iris/handle/10665/43942 |archive-url=https://web.archive.org/web/20220207114854/https://apps.who.int/iris/bitstream/handle/10665/43942/9789241563710_eng.pdf?sequence=1&isAllowed=y |archive-date=February 7, 2022 |access-date=October 6, 2022 |publisher=[[World Health Organization]] |hdl=10665/43942 |isbn=978-92-4-156371-0 |oclc=264018380}}
* <cite id="HNPGuindonBoisclair">{{Cite web|url=http://www1.worldbank.org/tobacco/pdf/Guindon-Past,%20current-%20whole.pdf|format=PDF|title=Past, current and future trends in tobacco use|accessdate=2008-01-02|author=G. Emmanuel Guindon, David Boisclair|last=|first=|authorlink=|coauthors=|date=|year=2003|month=|work=|publisher=The International Bank for Reconstruction and Development / The World Bank|location=Washington DC|pages=|language=|doi=|archiveurl=|archivedate=|quote=}}</cite>
* {{cite journal |title=Environmental causes of human cancers|author1=Montesano, R. |author2=Hall, J. |year=2001 |journal=European Journal of Cancer |volume=37 |pages=67–87 |doi=10.1016/S0959-8049(01)00266-0 |pmid=11602374 |ref=Montesano2001}}
* <cite id="WomenTobaccoChallenges21st">{{Cite web|url=http://www.who.int/tobacco/media/en/WomenMonograph.pdf|format=PDF|title=Women and the Tobacco Epidemic: Challenges for the 21st Century|accessdate=2009-01-02|author=The World Health Organization, and the Institute for Global Tobacco Control, Johns Hopkins School of Public Health|last=|first=|authorlink=|coauthors=|date=|year=2001|month=|work=|publisher=World Health Organization|location=|pages=|language=|doi=|archiveurl=|archivedate=|quote=}}</cite>
* <cite id="2001SurgeonGeneralWomen">{{Cite web|url=http://www.cdc.gov/tobacco/data_statistics/sgr/sgr_2001/sgr_women_chapters.htm|title=Surgeon General's Report — Women and Smoking|accessdate=2009-01-03|author=|last=|first=|authorlink=|coauthors=|date=|year=2001|month=|work=|publisher=Centers for Disease Control and Prevention|location=|pages=|language=|doi=|archiveurl=|archivedate=|quote=}}</cite>
* {{cite web |last1=Office of the Surgeon General |url=https://www.cdc.gov/tobacco/data_statistics/sgr/2001/|title=Surgeon General's Report — Women and Smoking |access-date=October 6, 2022 |year=2001 |publisher=[[United States Department of Health and Human Services|Department of Health and Human Services]] |ref={{SfnRef|Surgeon General's Report Women and Smoking|2001}}|author1-link=Surgeon General of the United States }}
* {{cite journal |author1=Paul Lichtenstein |author2=Niels V. Holm |author3=Pia K. Verkasalo |author4=Anastasia Iliadou |author5=Jaakko Kaprio |author6=Markku Koskenvuo |author7=Eero Pukkala |author8=Axel Skytthe |author9=Kari Hemminki |title=Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland |journal=New England Journal of Medicine |volume=343 |issue=2 |year=2000 |doi=10.1056/NEJM200007133430201 |pmid=10891514 |pages=78–85 |ref=Lichtenstein2000|doi-access=free }}
* <cite id="MortalityDevelopedOxford">{{Cite web|url=http://www.ctsu.ox.ac.uk/~tobacco/SMK_All_PAGES.pdf|format=PDF|title=Mortality from Smoking in Developed Countries 1950-2000: indirect estimates from national vital statistics|accessdate=2009-01-03|author=Richard Peto, Alan D Lopez, Jillian Boreham, and Michael Thun|last=|first=|authorlink=|coauthors=|date=|year=2006|month=|work=|publisher=Oxford University Press|location=New York, NY|pages=|language=|doi=|archiveurl=|archivedate=|quote=}}</cite>
* {{cite web |url=http://www.ctsu.ox.ac.uk/~tobacco/SMK_All_PAGES.pdf |title=Mortality from Smoking in Developed Countries 1950–2000: indirect estimates from national vital statistics |access-date=January 3, 2009 |author1=Richard Peto |author2=Alan D Lopez |author3=Jillian Boreham |author4=Michael Thun |year=2006 |publisher=Oxford University Press |location=New York|archive-url=https://web.archive.org/web/20050224232603/http://www.ctsu.ox.ac.uk/~tobacco/SMK_All_PAGES.pdf |archive-date=February 24, 2005|url-status=dead|ref=MortalityDevelopedOxford}}
* <cite id="SmokeGilmanZhou">{{cite book|last=|first=|authorlink=|coauthors=|first1=Sander L.|last1=Gilman|first2=Xun|last2=Zhou|editor=|others=|title=Smoke: A Global History of Smoking|url=http://books.google.com/?id=mM5bYb_uVcwC|format=|accessdate=2009-01-01|edition=|series=|volume=|date=|origyear=|year=2004|month=|publisher=Reaktion Books|location=|language=|isbn=9781861892003|oclc=|doi=|id=|page=|pages=|nopp=|chapter=|chapterurl=|quote=|ref=|bibcode=|laysummary=|laydate=|separator=|postscript=|lastauthoramp=}}</cite>
* {{cite web|url=https://www.who.int/tobacco/media/en/WomenMonograph.pdf|title=Women and the Tobacco Epidemic: Challenges for the 21st Century|access-date=January 2, 2009 |editor-last1=Samet |editor-first1=Jonathan M. |editor-link1=Jonathan Samet |editor-last2=Yoon |editor-first2=Soon-Young |editor-link2=Soon-Young Yoon |year=2001 |publisher=[[World Health Organization]], The Institute for Global Tobacco Control, [[Johns Hopkins Bloomberg School of Public Health|Johns Hopkins School of Public Health]] |archive-url=https://web.archive.org/web/20031128122821/http://www.who.int/tobacco/media/en/WomenMonograph.pdf|archive-date=November 28, 2003|url-status=dead |ref={{SfnRef|Samet & Yoon|2001}}}}
* <cite id="ACS2004">{{cite web
* {{Cite book |date=2008 |title=WHO Report on the Global Tobacco Epidemic 2008 : The MPOWER Package. |url=https://apps.who.int/iris/bitstream/handle/10665/43818/9789241596282_eng.pdf?sequence=1&isAllowed=y |archive-url=https://web.archive.org/web/20220121162003/https://apps.who.int/iris/bitstream/handle/10665/43818/9789241596282_eng.pdf?sequence=1&isAllowed=y |archive-date=January 21, 2022 |access-date=October 6, 2022 |publisher=[[World Health Organization]] |pages=6, 8, 20 |isbn=978-92-4-068311-2 |oclc=476167599}}
|url=http://tobaccodocuments.org/pm/2073777259-7269.html
* {{cite book |url=https://books.google.com/books?id=C3KhGwAACAAJ |title=Perique Tobacco Mystery and History: A Monograph |last1=Aristée Poché |first1=L. |year=2002}}
|title=Cancer Facts and Figures 2004: Basic Cancer Facts
* {{cite book |url=https://books.google.com/books?id=e7nNkB8R4GkC&pg=PP1 |title=Golden-Silk Smoke: A History of Tobacco in China, 1550–2010 |isbn=978-0-520-94856-3 |last1=Benedict |first1=Carol |year= 2011|publisher=University of California Press }}
|accessdate=2009-01-21
* {{cite book |url=https://books.google.com/books?id=Ro45DgAAQBAJ |title=The Cigarette Century: The Rise, Fall, and Deadly Persistence of the Product That Defined America|isbn = 978-0-7867-2190-0 |last1=Brandt |first1=Allan |year= 2009|publisher=Basic Books }}
|author=
* {{cite book |isbn=0-691-00596-6 |title=Tobacco Culture: The Mentality of the Great Tidewater Planters on the Eve of Revolution |last1=Breen |first1=T. H. |year=1985|publisher=Princeton University Press }}. ''Source on tobacco culture in 18th-century Virginia pp.&nbsp;46–55''
|last=
* {{cite book |url=https://books.google.com/books?id=cZfqS7vi9vEC |title=The Smoke of the Gods: A Social History of Tobacco |isbn=978-1-59213-482-3 |last1=Burns |first1=Eric |year= 2006|publisher=Temple University Press }}
|first=
* {{cite book |url=https://books.google.com/books?id=392vBQAAQBAJ |title=The Golden Leaf: How Tobacco Shaped Cuba and the Atlantic World |isbn=978-0-8265-2034-0 |last1=Cosner |first1=Charlotte |date=February 10, 2015|publisher=Vanderbilt University Press }}
|authorlink=
* {{cite news |last=Fuller |first=R. Reese |date=Spring 2003 |title=Perique, the Native Crop |work=Louisiana Life |url=http://www.reesefuller.com/articles/perique-the-native-crop/}}
|coauthors=
* {{cite book |url=https://books.google.com/books?id=x41jVocj05EC |title = Tobacco: A Cultural History of How an Exotic Plant Seduced Civilization |isbn=978-0-8021-9848-8 |last1=Gately |first1=Iain |date=December 2007|publisher = Open Road + Grove/Atlantic }}
|date=
* {{cite book |url=https://books.google.com/books?id=DP-HAgAAQBAJ |title=Tobacco in History: The Cultures of Dependence|isbn = 978-1-134-81840-2 |last1=Goodman |first1=Jordan |year= 2005|publisher=Routledge }}
|year=
* {{cite book |isbn=0-394-51238-3 |title=From a Limestone Ledge: Some Essays and Other Ruminations about Country Life in Texas |url=https://archive.org/details/fromlimestoneled00grav |url-access=registration |last1=Graves |first1=John |year=1980|publisher=Knopf }}
|month=
* {{cite journal |jstor=10.1086/ahr.111.5.1352 |doi=10.1086/ahr.111.5.1352 |pmid=17907367 |title=Smoking and "Early Modern" Sociability: The Great Tobacco Debate in the Ottoman Middle East (Seventeenth to Eighteenth Centuries) |journal=The American Historical Review |volume=111 |issue=5 |pages=1352–1377 |year=2006 |last1=Grehan |first1=James }}
|work=
* {{cite book |url=https://books.google.com/books?id=39KcvbVgHmEC |title = Making Tobacco Bright: Creating an American Commodity, 1617–1937|isbn = 978-1-4214-0286-4|last1 = Hahn|first1 = Barbara M.|year=2011| publisher=JHU Press }}; examines how marketing, technology, and demand figured in the rise of Bright Flue-Cured Tobacco, a variety first grown in the inland Piedmont region of the Virginia-North Carolina border.
|publisher=American Cancer Society
* {{cite book |url=https://books.google.com/books?id=3FsjAQAAMAAJ |title=Principles of Flue-Cured Tobacco Production |last1=Hawks |first1=S. N. |last2=Collins |first2=W. K. |year=1983}}
|location=
* {{cite book |url=https://archive.org/details/tobaccoleafitsc00myrigoog |title = Tobacco Leaf, Its Culture and Cure, Marketing and Manufacture: A Practical Handbook on the Most Approved Methods in Growing, Harvesting, Curing, Packing and Selling Tobacco, Also of Tobacco Manufacture|publisher=Orange Judd Company |last1 = Killebrew|first1 = Joseph Buckner|last2 = Myrick|first2 = Herbert|year = 1897}} ''Source for flea beetle typology (p.&nbsp;243)''
|pages=
* {{cite book |url=https://books.google.com/books?id=K_i1AAAACAAJ |author-link=Richard Kluger |title=Ashes to Ashes: America's Hundred-Year Cigarette War, the Public Health, and the Unabashed Triumph of Philip Morris |isbn=978-0-517-45110-6 |last1=Kluger |first1=Richard |year= 1999 |publisher=Random House Value }}, Pulitzer Prize
|language=
* {{cite book |isbn=978-0-7546-5931-0 |title=Studies on Ottoman Society and Culture, 16th–18th Centuries |last1=Murphey |first1=Rhoads |date= 2007|publisher=Ashgate Publishing Company }}
|doi=
* {{cite book |url=https://books.google.com/books?id=E7JDJzogCHMC&pg=PP1 |title=Balkan Smoke: Tobacco and the Making of Modern Bulgaria |isbn=978-0-8014-6550-5 |last1=Neuburger |first1=Mary C. |year= 2012 |publisher=Cornell University Press }}
|archiveurl=
* {{cite journal |jstor=1922038 |title=The Rise of Glasgow in the Chesapeake Tobacco Trade, 1707–1775 |journal=The William and Mary Quarterly |volume=11 |issue=2 |pages=179–199 |last1=Price |first1=Jacob M. |year=1954 |doi=10.2307/1922038}}
|archivedate=
* {{cite book |url=https://archive.org/details/historicalstatis01scho |title=Historical and statistical information respecting the history, condition and prospects of the Indian tribes of the United States: Collected and prepared under the direction of the Bureau of Indian Affairs per act of Congress of March 3rd, 1847|publisher=Historical American Indian Press |last1=Schoolcraft |first1=Henry Rowe |year=1851}}
|quote=
* {{cite book |isbn=1-84511-137-0 |title=Smoking, Culture and Economy in the Middle East |last1=Shechter |first1=Relli |year= 2006 |publisher=Bloomsbury Academic }}
}}</cite><!-- ACS. 2004. Cancer Facts and Figures 2004: Basic Cancer Facts. American Cancer Society. [http://cancer.org/statistics/cff99/basicfacts.html#risk.] --><!-- CITATION INCOMPLETE -->
* {{cite book |url=https://books.google.com/books?id=KtwkuAAACAAJ |title=The Bright Tobacco Industry, 1860–1929 |isbn=978-0-8078-7953-5 |last1=Tilley |first1=Nannie M. |year=2012|publisher=University of North Carolina Press }}
* <cite id="Lichtenstein2000">{{cite book|coauthors=Paul Lichtenstein, Ph.D., Niels V. Holm, M.D., Ph.D., Pia K. Verkasalo, M.D., Ph.D., Anastasia Iliadou, M.Sc., Jaakko Kaprio, M.D., Ph.D., Markku Koskenvuo, M.D., Ph.D., Eero Pukkala, Ph.D., Axel Skytthe, M.Sc., and Kari Hemminki, M.D., Ph.D.|title=Environmental and Heritable Factors in the Causation of Cancer — Analyses of Cohorts of Twins from Sweden, Denmark, and Finland|url=http://content.nejm.org/cgi/content/full/343/2/78|format=|accessdate=2009-01-21|edition=|series=|volume=343|date=|origyear=|year=2000|month=|publisher=New England Journal of Medicine|location=|language=|isbn=|oclc=|doi=|bibcode=|id=|page=|pages=|nopp=|chapter=|chapterurl=|quote=|ref=|laysummary=|laydate=|separator=|postscript=|lastauthoramp=}}</cite>
* <cite id="Montesano2001">{{cite web|url=http://www.journals.elsevierhealth.com/periodicals/ejc/article/PIIS0959804901002660/abstract|title=Environmental causes of human cancers|accessdate=2009-01-21|author=Montesano, R., and Hall, J.|last=|first=|authorlink=|coauthors=|date=|year=2001|month=|format=|work=|publisher=European Journal of Cancer|location=|pages=|language=|doi=|archiveurl=|archivedate=|quote=}}</cite>
<!-- CLEAN UP REFERENCES BELOW -->
* {{cite book
|last=Janet E. Ash, Maryadele J. O'Neil, Ann Smith, Joanne F. Kinneary
|first=|authorlink=|title=The Merck Index|origyear=1996|edition=12|year=1997|month=June
|publisher=Merk and Co.|isbn=0412759403}}
{{Refend}}


* Werner, Carl Avery. ''Tobaccoland: A book about tobacco; its history, legends, literature, cultivation, social and hygienic influences, commercial development, industrial processes and governmental regulation.'' (1922) [https://archive.org/details/tobaccolandbooka00wernuoft/page/n10/mode/1up online]
==Further reading==
{{Refbegin|colwidth=40em}}
<!-- CONVERT TO TEMPLATES; CHECK TO SEE IF IT CAN BE MOVED TO BIBLIOGRAPHY -->
* Breen, T. H. (1985). ''Tobacco Culture''. Princeton University Press. ISBN 0-691-00596-6. ''Source on tobacco culture in eighteenth-century Virginia pp.&nbsp;46–55''
* Burns, Eric. The Smoke of the Gods: A Social History of Tobacco. Philadelphia: Temple University Press, 2007.
* W.K. Collins and S.N. Hawks. "Principles of Flue-Cured Tobacco Production" 1st Edition, 1993
* Fuller, R. Reese (Spring 2003). Perique, the Native Crop. ''Louisiana Life''.
* Gately, Iain. ''Tobacco: A Cultural History of How an Exotic Plant Seduced Civilization.'' Grove Press, 2003. ISBN 0-8021-3960-4.
* Graves, John. "Tobacco that is not Smoked" in ''From a Limestone Ledge'' (the sections on snuff and chewing tobacco) ISBN 0-394-51238-3
* Grehan, James. “Smoking and “Early Modern” Sociability: The Great Tobacco Debate in the Ottoman Middle East (Seventeenth to Eighteenth Centuries)”. ''The American Historical Review, Vol. III, Issue 5''. 2006. 22 March 2008 http://www.historycooperative.org.myaccess.library.utoronto.ca/journals/ahr/111.5/grehan.html
* Killebrew, J. B. and Myrick, Herbert (1909). ''Tobacco Leaf: Its Culture and Cure, Marketing and Manufacture.'' Orange Judd Company. ''Source for flea beetle typology (p.&nbsp;243)''
* Murphey, Rhoads. ''Studies on Ottoman Society and Culture: 16th-18th Centuries''. Burlington, VT: Ashgate: Variorum, 2007 ISBN 978-0-7546-5931-0 ISBN 0-7546-5931-3
* Price, Jacob M. “Tobacco Use and Tobacco Taxation: A battle of Interests in Early Modern Europe”. ''Consuming Habits: Drugs in History and Anthropology''. Jordan Goodman, et al. New York: Routledge, 1995 166-169 ISBN 0-415-09039-3
* Poche, L. Aristee (2002). ''Perique tobacco: Mystery and history''.
* Tilley, Nannie May ''The Bright Tobacco Industry 1860–1929'' ISBN 0-405-04728-2. ''Source on flea beetle prevention (pp.&nbsp;39–43), and history of flue-cured tobacco''
* Rivenson A., Hoffmann D., Propokczyk B. et al. [http://intl-cancerres.aacrjournals.org/cgi/content/abstract/48/23/6912 Induction of lung and pancreas exocrine tumors in F344 rats by tobacco-specific and areca-derived N-nitrosamines.] Cancer Res (48) 6912–6917, 1988. (link to abstract; free full text pdf available)
* Schoolcraft, Henry R. Historical and Statistical Information respecting the Indian Tribes of the United States (Philadelphia, 1851–57)
* Shechter, Relli. ''Smoking, Culture and Economy in the Middle East: The Egyptian Tobacco Market 1850–2000''. New York: I.B. Tauris & Co. Ltd., 2006 ISBN 1-84511-137-0
{{Refend}}


==External links==
==External links==
{{Commons}}
{{Wikiquote}}


* [https://www.who.int/news-room/fact-sheets/detail/tobacco WHO fact sheet on tobacco]
{{Sisterlinks

|wikt=Tobacco
{{Plantation agriculture in the Southeastern United States}}
|b=Tobacco
{{Psychoactive substance use}}
|q=Tobacco
{{Drug use}}
|s=Tobacco
{{Cigarettes}}
|commons=Category:Tobacco
{{Navboxes
|n=Tobacco
| title = [[Pharmacodynamics]]
|v=Category:Tobacco
| titlestyle = background:#ccccff
| list1 =
{{Monoamine metabolism modulators}}
{{Nicotinic acetylcholine receptor modulators}}
{{Transient receptor potential channel modulators}}
}}
}}
{{Authority control}}


[[Category:Anaphrodisia]]
{{Refbegin}}
* [http://www.plot55.com/growing/nicotiana.html Growing Nicotiana species (Plot55.com)]
* [http://plants.nrcs.usda.gov/factsheet/pdf/fs_niru.pdf Natural Resources Conservation Service Plant Sheet - Wild tobacco]
* [http://www.obarsiv.com/english/archive.html Ottoman Back Archives and Research Centre]
* [http://news.bbc.co.uk/2/hi/health/3300769.stm Questions on European Union partial ban on some smokeless tobacco products (''i.e.'' snus)]
* [http://www.voanews.com/english/archive/2005-11/2005-11-30-voa79.cfm?CFID=60937799&CFTOKEN=87949569 Scientists Search for Healthy Uses for Tobacco]
* [http://www.tobacco.org/resources/history/Tobacco_History.html/ Timeline of tobacco history]
* [http://www.savetobaccogrowers.com/ The European tobacco growers website]
* [http://legacy.library.ucsf.edu/ The Legacy Tobacco Documents Library]
* [http://www.archive.org/details/tobaccoarchives UCSF Tobacco Industry Videos Collection]
* [http://www.cdc.gov/tobacco/data_statistics/fact_sheets/fast_facts/index.htm CDC - Smoking and Tobacco Use Fact Sheet]
* [http://www.who.int/tobacco/global_interaction/tobreg/en/ TobReg] - WHO Study Group on Tobacco Product Regulation
{{Refend}}

[[Category:Tobacco| ]]
[[Category:Tobacco| ]]
[[Category:CYP1A2 inducers]]
[[Category:Crops originating from the Americas]]
[[Category:Entheogens]]
[[Category:Entheogens]]
[[Category:Herbal and fungal stimulants]]
[[Category:Herbal and fungal stimulants]]
[[Category:Leaves]]
[[Category:Monoamine oxidase inhibitors]]
[[Category:Monoamine oxidase inhibitors]]
[[Category:Native American religion]]
[[Category:Native American religion]]
[[Category:Nicotinic antagonists]]
[[Category:Nicotinic agonists]]
[[Category:Crops originating from the Americas]]
[[Category:IARC Group 1 carcinogens]]

{{Link FA|mk}}
[[ang:Pīpwēod]]
[[ar:تبغ]]
[[an:Tabaco]]
[[zh-min-nan:Hun-chháu]]
[[be:Тытунь]]
[[bs:Duhan]]
[[bg:Тютюн]]
[[ca:Tabac]]
[[cs:Tabák]]
[[cy:Tybaco]]
[[da:Tobak]]
[[de:Tabak]]
[[el:Καπνός (φυτό)]]
[[es:Tabaco]]
[[eo:Tabako]]
[[fa:تنباکو]]
[[fr:Tabac]]
[[gl:Tabaco]]
[[ko:담배 (식물)]]
[[hr:Duhan]]
[[id:Tembakau]]
[[is:Tóbak]]
[[he:טבק]]
[[jv:Tembako]]
[[sw:Mtumbako]]
[[la:Tabacum]]
[[lv:Tabaka]]
[[lb:Tubak]]
[[lt:Tabakas]]
[[hu:Dohány]]
[[mk:Тутун]]
[[ml:പുകയില]]
[[nah:Piciyetl]]
[[nl:Tabak]]
[[ja:タバコ]]
[[no:Tobakk]]
[[nn:Tobakk]]
[[nrm:P'tun]]
[[pl:Tytoń]]
[[pt:Tabaco]]
[[ro:Tutun]]
[[ru:Табак]]
[[sq:Duhani]]
[[simple:Tobacco]]
[[sr:Дуван]]
[[sh:Duhan]]
[[su:Bako]]
[[sv:Tobak]]
[[fi:Tupakka]]
[[tl:Tabako]]
[[ta:புகையிலை]]
[[tr:Tütün]]
[[uk:Тютюн]]
[[vi:Thuốc lá (nông phẩm)]]
[[fiu-vro:Tubak]]
[[vls:Toebak]]
[[war:Tabakò]]
[[yi:טאבאק]]
[[bat-smg:Taboks]]
[[zh:烟草]]

Latest revision as of 04:52, 20 December 2024

Tobacco
Tobacco flakes, sliced from pressed plugs
Source plant(s)Nicotiana
Part(s) of plantLeaf
Geographic originThe Americas
Active ingredientsNicotine, harmine
UsesRecreational, Sacred, Medical, Religious, Traditional, Peacemaking
Legal status
  • AU: Unscheduled
  • BR: Class E (Controlled plants)
  • CA: Unscheduled
  • DE: Unscheduled
  • UK: General sales list (GSL, OTC)
  • US: Unscheduled
  • UN: Unscheduled
  • In general, legal and regulated as a controlled substance for recreational use in most countries, tobacco smuggling or homemade tobacco making or growing is illegal. See tobacco control
Tobacco drying kiln in Myrtleford, Victoria, Australia, 2018. This kiln was built in 1957, and moved to Rotary Park in 2000. Kilns of this design were built from the early 1930s through to the late 1960s.
Basma tobacco leaves drying in the sun at Pomak village in Xanthi, Greece

Tobacco is the common name of several plants in the genus Nicotiana of the family Solanaceae, and the general term for any product prepared from the cured leaves of these plants. More than 70 species of tobacco are known, but the chief commercial crop is N. tabacum. The more potent variant N. rustica is also used in some countries.

Dried tobacco leaves are mainly used for smoking in cigarettes and cigars, as well as pipes and shishas. They can also be consumed as snuff, chewing tobacco, dipping tobacco, and snus.

Tobacco contains the highly addictive stimulant alkaloid nicotine as well as harmala alkaloids.[1] Tobacco use is a cause or risk factor for many deadly diseases, especially those affecting the heart, liver, and lungs[2] as well as many cancers. In 2008, the World Health Organization named tobacco use as the world's single greatest preventable cause of death.[3]

In Minas Gerais, Brazil

Etymology

[edit]

The English word 'tobacco' originates from the Spanish word tabaco.[4] The precise origin of this word is disputed, but it is generally thought to have derived, at least in part, from Taíno, the Arawakan language of the Caribbean. In Taíno, it was said to mean either a roll of tobacco leaves (according to Bartolomé de las Casas, 1552), or to tabago, a kind of L-shaped pipe used for sniffing tobacco smoke (according to Oviedo, with the leaves themselves being referred to as cohiba).[5][4]

However, perhaps coincidentally, similar words in Spanish, Portuguese and Italian were used from 1410 for certain medicinal herbs. These probably derived from the Arabic طُبّاق ṭubbāq (also طُباق ṭubāq), a word reportedly dating to the ninth century, referring to various herbs.[6][7]

History

[edit]
William Michael Harnett (American, 1848–1892), Still Life with Three Castles Tobacco, 1880, Brooklyn Museum

Cultural significance

[edit]

According to Iroquois mythology, tobacco first grew out of Earth Woman's head after she died giving birth to her twin sons, Sapling and Flint.[8]

Traditional use

[edit]
The earliest depiction of a European man smoking, from Tobacco by Anthony Chute, 1595
An Indian man smoking tobacco through a hookah, Rajasthan, India

Tobacco has long been used in the Americas, with some cultivation sites in Mexico dating back to 1400–1000 BC.[9] Many Native American tribes traditionally grow and use tobacco.[10] Historically, people from the Northeast Woodlands cultures have carried tobacco in pouches as a readily accepted trade item. It was smoked both socially and ceremonially, such as to seal a peace treaty or trade agreement.[11][12] In some Native cultures, tobacco is seen as a gift from the Creator, with the ceremonial tobacco smoke carrying one's thoughts and prayers to the Creator.[13]

Some Native Americans consider tobacco to be a medicine and advocate for its respectful usage, rather than a commercial one.[14]

Popularization

[edit]
An illustration from Frederick William Fairholt's Tobacco, its History and Association, 1859
Tobacco plant and tobacco leaf from the Deli plantations in Sumatra, 1905

Following the arrival of the Europeans to the Americas, tobacco became increasingly popular as a trade item. Francisco Hernández de Toledo, Spanish chronicler of the Indies, was the first European to bring tobacco seeds to the Old World in 1559 following orders of King Philip II of Spain. These seeds were planted in the outskirts of Toledo, more specifically in an area known as "Los Cigarrales" named after the continuous plagues of cicadas (cigarras in Spanish). Before the development of the lighter Virginia and white burley strains of tobacco, the smoke was too harsh to be inhaled. Small quantities were smoked at a time, using a pipe like the midwakh or kiseru, or newly invented waterpipes such as the bong or the hookah (see thuốc lào for a modern continuance of this practice). Tobacco became so popular that the English colony of Jamestown used it as currency and began exporting it as a cash crop; tobacco is often credited as being the export that saved Virginia from ruin.[15] While a lucrative product, the growing expansion of tobacco demand was intimately tied to the history of slavery in the Caribbean. [16]

The alleged benefits of tobacco also contributed to its success. The astronomer Thomas Harriot, who accompanied Sir Richard Grenville on his 1585 expedition to Roanoke Island, thought that the plant "openeth all the pores and passages of the body" so that the bodies of the natives "are notably preserved in health, and know not many grievous diseases, wherewithal we in England are often times afflicted."[17]

Production of tobacco for smoking, chewing, and snuffing became a major industry in Europe and its colonies by 1700.[18][19]

Tobacco has been a major cash crop in Cuba and in other parts of the Caribbean since the 18th century. Cuban cigars are world-famous.[20]

In the late 19th century, cigarettes became popular. James Bonsack invented a machine to automate cigarette production. This increase in production allowed tremendous growth in the tobacco industry until the health revelations of the late 20th century.[21][22]

Contemporary

[edit]

Following the scientific revelations of the mid-20th century, tobacco was condemned as a health hazard, and eventually became recognized as a cause of cancer, as well as other respiratory and circulatory diseases. In the United States, this led to the adoption of the 1998 Tobacco Master Settlement Agreement, which settled the many lawsuits by the U.S. states in exchange for a combination of yearly payments to the states and voluntary restrictions on advertising and marketing of tobacco products.[23]

In the 1970s, Brown & Williamson cross-bred a strain of tobacco to produce Y1, a strain containing an unusually high nicotine content, nearly doubling from 3.2 to 3.5%, to 6.5%. In the 1990s, this prompted the Food and Drug Administration to allege that tobacco companies were intentionally manipulating the nicotine content of cigarettes.[24]

The desire of many addicted smokers to quit has led to the development of tobacco cessation products.[25]

In 2003, in response to growth of tobacco use in developing countries, the World Health Organization[26] successfully rallied 168 countries to sign the Framework Convention on Tobacco Control. The convention is designed to push for effective legislation and enforcement in all countries to reduce the harmful effects of tobacco.[27] Between 2019 and 2021, concerns about increased COVID-19 health risks due to tobacco consumption facilitated smoking reduction and cessation.[28]

Biology

[edit]

Nicotiana

[edit]
Nicotine is the compound responsible for the addictive nature of tobacco use.
Tobacco (Nicotiana rustica) flower, leaves, and buds

Many species of tobacco are in the genus of herbs Nicotiana. It is part of the nightshade family (Solanaceae) indigenous to North and South America, Australia, south west Africa, and the South Pacific.[29]

Most nightshades contain varying amounts of nicotine, a powerful neurotoxin to insects. However, tobaccos tend to contain a much higher concentration of nicotine than the others. Unlike many other Solanaceae species, they do not contain tropane alkaloids, which are often poisonous to humans and other animals.

Despite containing enough nicotine and other compounds such as germacrene and anabasine and other piperidine alkaloids (varying between species) to deter most herbivores,[30] a number of such animals have evolved the ability to feed on Nicotiana species without being harmed. Nonetheless, tobacco is unpalatable to many species due to its other attributes. For example, although the cabbage looper is a generalist pest, tobacco's gummosis and trichomes can harm early larvae survival.[31] As a result, some tobacco plants (chiefly N. glauca) have become established as invasive weeds in some places.

Types

[edit]

The types of tobacco include:

  • Aromatic fire-cured is cured by smoke from open fires. In the United States, it is grown in northern middle Tennessee, central Kentucky, and Virginia. Fire-cured tobacco grown in Kentucky and Tennessee is used in some chewing tobaccos, moist snuff, some cigarettes, and as a condiment in pipe tobacco blends. Another fire-cured tobacco is Latakia, which is produced from oriental varieties of N. tabacum. The leaves are cured and smoked over smoldering fires of local hardwoods and aromatic shrubs in Cyprus and Syria.
  • Brightleaf tobacco is commonly known as "Virginia tobacco", often regardless of the state where it is planted. Prior to the American Civil War, most tobacco grown in the US was fire-cured dark-leaf. Sometime after the War of 1812, demand for a milder, lighter, more aromatic tobacco arose. Ohio, Pennsylvania and Maryland all innovated with milder varieties of the tobacco plant. Farmers discovered that brightleaf tobacco needs thin, starved soil, and those who could not grow other crops found that they could grow tobacco. Confederate soldiers traded it with each other and Union soldiers, and developed quite a taste for it. At the end of the war, the soldiers went home and a national market had developed for the local crop.
  • Broadleaf, a dark tobacco varietal family popular for producing enormous, resilient, and thick wrapper leaves.[citation needed]
  • Burley tobacco is an air-cured tobacco used predominantly in cigarette production, but also in pipe tobacco as a balance to Virginias and other leaves high in sugar content. In the U.S., burley tobacco plants are started from pelletized seeds placed in polystyrene trays floated on a bed of fertilized water in March or April.
  • Cavendish is more a process of curing and a method of cutting tobacco than a type, but is used to thicken flavors from other tobaccos that might lack a body. The processing and the cut are used to bring out the natural sweet taste in the tobacco. Cavendish can be produced from any tobacco type but is usually one of, or a blend of, Kentucky, Virginia and burley and is most commonly used for pipe tobacco.
  • Criollo tobacco is primarily used in the making of cigars. It was by most accounts one of the original Cuban tobaccos that emerged around the time of Columbus.
  • Dokha is a tobacco originally grown in Iran, mixed with leaves, bark and herbs for smoking in a midwakh.
  • Perique was developed in 1824 through the technique of pressure-fermentation of local tobacco by a farmer, Pierre Chenet. Considered the truffle of pipe tobaccos, it is used as a component in many blended pipe tobaccos but is too strong to be smoked pure. At one time the freshly moist Perique was also chewed, but it is no longer sold for this purpose. It is typically blended with pure Virginia to lend spice, strength and coolness to the blend.
  • Shade tobacco is cultivated in Connecticut and Massachusetts. Early Connecticut colonists acquired from the Native Americans the habit of smoking tobacco in pipes, and began cultivating the plant commercially, though the Puritans referred to it as the "evil weed". The Connecticut shade industry has weathered some major catastrophes, including a devastating hailstorm in 1929 and an epidemic of brown spot fungus in 2000, and is in danger of disappearing altogether, given the increase in the value of land.
  • Turkish tobacco is a sun-cured, highly aromatic, small-leafed variety (Nicotiana tabacum) grown in Turkey, Greece, Bulgaria and North Macedonia. Originally grown in regions historically part of the Ottoman Empire, it is also known as ‘oriental’. Many of the early brands of cigarettes were made mostly or entirely of Turkish tobacco. Its main use evolved to be included in blends of pipe and especially cigarette tobacco. (A typical American cigarette is a blend of bright Virginia, burley and Turkish.)
  • White burley air-cured leaf was found to be milder than other types of tobacco. In 1865 George Webb of Brown County, Ohio, planted red burley seeds he had purchased and found a few of the seedlings had a whitish, sickly look, which became white burley.
  • Wild tobacco is native to the southwestern United States, Mexico and parts of South America. Its botanical name is Nicotiana rustica.

Parasites

[edit]
Illustration with photographs of tobacco leaves infested by Lasioderma serricorne (tobacco beetles), from Runner, G. A., The tobacco beetle (1919), Bulletin of the U.S. Department of Agriculture, Biodiversity Heritage Library

Tobacco, alongside its related products, can be infested by parasites such as the Lasioderma serricorne (tobacco beetle) and the Ephestia elutella (tobacco moth), which are the most widespread and damaging parasites to the tobacco industry.[32] Infestation can range from the tobacco cultivated in the fields to the leaves used for manufacturing cigars, cigarillos, cigarettes, etc.[32] Both the larvae of Lasioderma serricorne and caterpillars of Ephestia elutella are considered pests.[32]

Production

[edit]

Cultivation

[edit]
Tobacco plants growing in a field in Intercourse, Pennsylvania

Tobacco is cultivated similarly to other agricultural products. Seeds were at first quickly scattered onto the soil. However, young plants came under increasing attack from flea beetles (Epitrix cucumeris or E. pubescens), which caused destruction of half the tobacco crops in United States in 1876. By 1890, successful experiments were conducted that placed the plant in a frame covered by thin cotton fabric. Modern tobacco seeds are sown in cold frames or hotbeds, as their germination is activated by light.[33] In the United States, tobacco is often fertilized with the mineral apatite, which partially starves the plant of nitrogen, to produce a more desired flavor.

After the plants are about 8 inches (20 cm) tall, they are transplanted into the fields. Farmers used to have to wait for rainy weather to plant.[34] A hole is created in the tilled earth with a tobacco peg, either a curved wooden tool or deer antler. After making two holes to the right and left, the planter would move forward two feet, select plants from his/her bag, and repeat. Various mechanical tobacco planters like Bemis, New Idea Setter, and New Holland Transplanter were invented in the late 19th and 20th centuries to automate the process: making the hole, watering it, guiding the plant in—all in one motion.[35]

Tobacco is cultivated annually, and can be harvested in several ways. In the oldest method, still used, the entire plant is harvested at once by cutting off the stalk at the ground with a tobacco knife; it is then speared onto sticks, four to six plants a stick, and hung in a curing barn. In the 19th century, bright tobacco began to be harvested by pulling individual leaves off the stalk as they ripened. The leaves ripen from the ground upwards, so a field of tobacco harvested in this manner entails the serial harvest of a number of "primings", beginning with the volado leaves near the ground, working to the seco leaves in the middle of the plant, and finishing with the potent ligero leaves at the top. Before harvesting, the crop must be topped when the pink flowers develop. Topping always refers to the removal of the tobacco flower before the leaves are systematically harvested. As the industrial revolution took hold, the harvesting wagons which were used to transport leaves were equipped with man-powered stringers, an apparatus that used twine to attach leaves to a pole. In modern times, large fields are harvested mechanically, although topping the flower and in some cases the plucking of immature leaves is still done by hand.

In the U.S., North Carolina and Kentucky are the leaders in tobacco production, followed by Tennessee, Virginia, Georgia, South Carolina and Pennsylvania.[36]

Curing

[edit]
Tobacco barn in Simsbury, Connecticut used for air curing of shade tobacco
Sun-cured tobacco, Bastam, Iran

Curing and subsequent aging allow for the slow oxidation and degradation of carotenoids in tobacco leaf. This produces certain compounds in the tobacco leaves and gives a sweet hay, tea, rose oil, or fruity aromatic flavor that contributes to the "smoothness" of the smoke. Starch is converted to sugar, which glycates protein, which is oxidized into advanced glycation endproducts (AGEs), a caramelization process that also adds flavor. Inhalation of these AGEs in tobacco smoke contributes to atherosclerosis and cancer.[37] Levels of AGEs are dependent on the curing method used.

Tobacco can be cured through several methods, including:

  • Air-cured tobacco is hung in well-ventilated barns and allowed to dry over a period of four to eight weeks. Air-cured tobacco is low in sugar, which gives the tobacco smoke a light, mild flavor, and high in nicotine. Cigar and burley tobaccos are 'dark' air-cured.[38]
  • Fire-cured tobacco is hung in large barns where fires of hardwoods are kept on continuous or intermittent low smoulder, and takes between three days and ten weeks, depending on the process and the tobacco. Fire curing produces a tobacco low in sugar and high in nicotine. Pipe tobacco, chewing tobacco, and snuff are fire-cured.
  • Flue-cured tobacco was originally strung onto tobacco sticks, which were hung from tier poles in curing barns (Aus: kilns, also traditionally called 'oasts'). These barns have flues run from externally fed fire boxes, heat-curing the tobacco without exposing it to smoke, slowly raising the temperature over the course of the curing. The process generally takes about a week. This method produces cigarette tobacco that is high in sugar and has medium to high levels of nicotine. Most cigarettes incorporate flue-cured tobacco, which produces a milder, more inhalable smoke. It is estimated that 1 tree is cut to flue-cure every 300 cigarettes, resulting in serious environmental consequences.[39]
  • Sun-cured tobacco dries uncovered in the sun. This method is used in Turkey, Greece, and other Mediterranean countries to produce oriental tobacco. Sun-cured tobacco is low in sugar and nicotine and is used in cigarettes.

Some tobaccos go through a second stage of curing, known as fermenting or sweating.[citation needed] Cavendish undergoes fermentation pressed in a casing solution containing sugar and/or flavoring.[citation needed]

Global production

[edit]
Tobacco production, 2018[40]
[edit]
Tobacco production in Portuguese Timor in the 1930s

Production of tobacco leaf increased by 40% between 1971, when 4.2 million tons of leaf were produced, and 1997, when 5.9 million tons of leaf were produced.[41] According to the Food and Agriculture Organization (FAO) of the United Nations, tobacco leaf production was expected to hit 7.1 million tons by 2010. This number is a bit lower than the record-high production of 1992, when 7.5 million tons of leaf were produced.[42] The production growth was almost entirely due to increased productivity by developing nations, where production increased by 128%.[43] During that same time, production in developed countries actually decreased.[42] China's increase in tobacco production was the single biggest factor in the increase in world production. China's share of the world market increased from 17% in 1971 to 47% in 1997.[41] This growth can be partially explained by the existence of a low import tariff on foreign tobacco entering China. While this tariff was reduced from 66% in 1999 to 10% in 2004,[44] it has still led to local Chinese cigarettes being preferred over foreign cigarettes because of their lower cost.

Major producers

[edit]
Top tobacco producers, 2020[45]
Country Production (tonnes) Note
 China 2,134,000
 India 761,335
 Brazil 702,208 F
 Zimbabwe 203,488
 Indonesia 199,737 F
 United States 176,635
 Mozambique 158,532 F
 Pakistan 132,872 F
 Argentina 109,333
 Malawi 93,613 F
 World 5,886,147 A
No note = official figure, F = FAO Estimate, A = Aggregate (may include official, semiofficial or estimates).

Every year, about 5.9 million tons of tobacco are produced throughout the world. The top producers of tobacco are China (36.3%), India (12.9%), Brazil (11.9%) and Zimbabwe (3.5%).[45]

China

[edit]

Around the peak of global tobacco production, 20 million rural Chinese households were producing tobacco on 2.1 million hectares of land.[46] While it is the major crop for millions of Chinese farmers, growing tobacco is not as profitable as cotton or sugarcane, because the Chinese government sets the market price. While this price is guaranteed, it is lower than the natural market price, because of the lack of market risk. To further control tobacco in their borders, China founded a State Tobacco Monopoly Administration (STMA) in 1982. The STMA controls tobacco production, marketing, imports, and exports, and contributes 12% to the nation's national income.[47] As noted above, despite the income generated for the state by profits from state-owned tobacco companies and the taxes paid by companies and retailers, China's government has acted to reduce tobacco use.[48]

India

[edit]

India's Tobacco Board is headquartered in Guntur in the state of Andhra Pradesh.[49] India has 96,865 registered tobacco farmers[50] and many more who are not registered. In 2010, 3,120 tobacco product manufacturing facilities were operating in all of India.[51] Around 0.25% of India's cultivated land is used for tobacco production.[46]

Since 1947, the Indian government has supported growth in the tobacco industry. India has seven tobacco research centers, located in Tamil Nadu, Andhra Pradesh, Punjab, Bihar, Mysore, and West Bengal which houses the core research institute.

Brazil

[edit]

In Brazil, around 135,000 family farmers cite tobacco production as their main economic activity.[46] Tobacco has never exceeded 0.7% of the country's total cultivated area.[52] In the southern regions of Brazil, Virginia, and Amarelinho, flue-cured tobacco, as well as burley and Galpão Comum air-cured tobacco, are produced. These types of tobacco are used for cigarettes. In the northeast, darker, air- and sun-cured tobacco is grown. These types of tobacco are used for cigars, twists, and dark cigarettes.[52] Brazil's government has made attempts to reduce the production of tobacco but has not had a successful systematic antitobacco farming initiative. Brazil's government, however, provides small loans for family farms, including those that grow tobacco, through the Programa Nacional de Fortalecimento da Agricultura Familiar.[53]

Tobacco plantation, Pinar del Río, Cuba

Problems in production

[edit]

Child labor

[edit]

The International Labour Office reported that the most child-laborers work in agriculture, which is one of the most hazardous types of work.[54] The tobacco industry houses some of these working children. Use of children is widespread on farms in Brazil, China, India, Indonesia, Malawi, and Zimbabwe.[55][56][57][58] While some of these children work with their families on small, family-owned farms, others work on large plantations. In late 2009, reports were released by the London-based human-rights group Plan International, claiming that child labor was common on Malawi (producer of 1.8% of the world's tobacco[41]) tobacco farms. The organization interviewed 44 teens, who worked full-time on farms during the 2007–08 growing season. The child-laborers complained of low pay and long hours, as well as physical and sexual abuse by their supervisors.[59] They also reported experiencing green tobacco sickness, a form of nicotine poisoning. When wet leaves are handled, nicotine from the leaves gets absorbed in the skin and causes nausea, vomiting, and dizziness. Children were exposed to levels of nicotine equivalent to smoking 50 cigarettes, just through direct contact with tobacco leaves.[59] The effects of nicotine on human brain development in children can permanently alter brain structure and function.[60]

Economy

[edit]
Tobacco harvesting, Viñales Valley, Cuba

Major tobacco companies have encouraged global tobacco production. Philip Morris, British American Tobacco, and Japan Tobacco each own or lease tobacco-manufacturing facilities in at least 50 countries and buy crude tobacco leaf from at least 12 more countries.[61] This encouragement, along with government subsidies, has led to a glut in the tobacco market. This surplus has resulted in lower prices, which are devastating to small-scale tobacco farmers. According to the World Bank, between 1985 and 2000, the inflation-adjusted price of tobacco dropped 37%.[62] Tobacco is the most widely smuggled legal product.[63]

Environment

[edit]

Tobacco production requires the use of large amounts of pesticides. Tobacco companies recommend up to 16 separate applications of pesticides just in the period between planting the seeds in greenhouses and transplanting the young plants to the field.[64] Pesticide use has been worsened by the desire to produce larger crops in less time because of the decreasing market value of tobacco. Pesticides often harm tobacco farmers because they are unaware of the health effects and the proper safety protocol for working with pesticides. These pesticides, as well as fertilizers, end up in the soil, waterways, and the food chain.[65] Coupled with child labor, pesticides pose an even greater threat. Early exposure to pesticides may increase a child's lifelong cancer risk, as well as harm their nervous and immune systems.[66]

As with all crops, tobacco crops extract nutrients (such as phosphorus, nitrogen, and potassium) from soil, decreasing its fertility.[67]

Furthermore, the wood used to cure tobacco in some places leads to deforestation. While some big tobacco producers such as China and the United States have access to petroleum, coal, and natural gas, which can be used as alternatives to wood, most developing countries still rely on wood in the curing process.[67] Brazil alone uses the wood of 60 million trees per year for curing, packaging, and rolling cigarettes.[64]

In 2017 WHO released a study on the environmental effects of tobacco.[39]

Research

[edit]

Several tobacco plants have been used as model organisms in genetics. Tobacco BY-2 cells, derived from N. tabacum cultivar 'Bright Yellow-2', are among the most important research tools in plant cytology.[68] Tobacco has played a pioneering role in callus culture research and the elucidation of the mechanism by which kinetin works, laying the groundwork for modern agricultural biotechnology. The first genetically modified plant was produced in 1982, using Agrobacterium tumefaciens to create an antibiotic-resistant tobacco plant.[69] This research laid the groundwork for all genetically modified crops.[70]

Genetic modification

[edit]

Because of its importance as a research tool, transgenic tobacco was the first genetically modified (GM) crop to be tested in field trials, in the United States and France in 1986; China became the first country in the world to approve commercial planting of a GM crop in 1993, which was tobacco.[71]

Field trials

[edit]

Many varieties of transgenic tobacco have been intensively tested in field trials. Agronomic traits such as resistance to pathogens (viruses, particularly to the tobacco mosaic virus (TMV); fungi; bacteria and nematodes); weed management via herbicide tolerance; resistance against insect pests; resistance to drought and cold; and production of useful products such as pharmaceuticals; and use of GM plants for bioremediation, have all been tested in over 400 field trials using tobacco.[72]

Production

[edit]

Currently, only the US is producing GM tobacco.[71][72] The Chinese virus-resistant tobacco was withdrawn from the market in China in 1997.[73]: 3  From 2002 to 2010, cigarettes made with GM tobacco with reduced nicotine content were available in the US under the market name Quest.[72][74]

Consumption

[edit]

Tobacco is consumed in many forms and through a number of different methods. Some examples are:

Enema

[edit]
  • Tobacco smoke enemas were employed by the indigenous peoples of North America to stimulate respiration, injecting the smoke with a rectal tube.[75][76][77][78] Later, in the 18th century, Europeans emulated the Americans.[79] Tobacco resuscitation kits consisting of a pair of bellows and a tube were provided by the Royal Humane Society of London and placed at various points along the Thames.[80]

Nasal administration

[edit]
  • Snuff is a ground smokeless tobacco product, inhaled or ‘snuffed’ through the nose. If referring specifically to the orally consumed moist snuff, see dipping tobacco.

Smoked

[edit]
  • Beedi (also known as bidis or biris) are thin, often flavoured cigarettes from India made of tobacco wrapped in a tendu leaf, and secured with coloured thread at one end.[81]
  • Cigarettes are a product consumed through inhalation of smoke and manufactured from cured and finely cut tobacco leaves and reconstituted tobacco, often combined with other additives, then rolled into a paper cylinder.
  • Cigars are tightly rolled bundles of dried and fermented tobacco, which are ignited so their smoke may be drawn into the smokers' mouths.
  • Dokha is a middle eastern tobacco with high nicotine levels grown in parts of Oman and Hatta, which is smoked through a thin pipe called a medwakh. It is a form of tobacco which is dried up and ground and contains little to no additives excluding spices, fruits, or flowers to enhance smell and flavor.
  • Heat-not-burn products heat rather than burn tobacco to generate an aerosol that contains nicotine.
  • Hookah is a single- or multistemmed (often glass-based) water pipe for smoking. Hookahs were first used in India and Persia;[82] the hookah has gained immense popularity, especially in the Middle East. A hookah operates by water filtration and indirect heat. It can be used for smoking herbal fruits or moassel, a mixture of tobacco, flavouring, and honey or glycerin.
  • Roll-your-own, often called 'rollies' or 'roll-ups', are relatively popular in some European countries. These are prepared from loose tobacco, cigarette papers, and filters all bought separately. They are usually cheaper to make.
  • Tobacco pipes typically consist of a small chamber (the bowl) for the combustion of the tobacco to be smoked and a thin stem (shank) that ends in a mouthpiece (the bit). Shredded pieces of tobacco are placed in the chamber and ignited.

In the mouth

[edit]

Tobacco used in the mouth (buccal (sublabial), sublingual):

  • Chewing tobacco is the oldest way of consuming tobacco leaves. It is consumed orally, in two forms: through sweetened strands ("chew" or "chaw"), or in a shredded form ("dip"). When consuming the long, sweetened strands, the tobacco is lightly chewed and compacted into a ball. When consuming the shredded tobacco, small amounts are placed inside the bottom lip, between the gum and the teeth, where it is gently compacted, thus it is often called dipping tobacco. Both methods stimulate the salivary glands, which led to the development of the spittoon.
  • Creamy snuff is tobacco paste, consisting of tobacco, clove oil, glycerin, spearmint, menthol, and camphor, and sold in a toothpaste tube. It is marketed mainly to women in India and is known by the brand names Ipco (made by Asha Industries), Denobac, Tona, and Ganesh. It is locally known as mishri in some parts of Maharashtra.
  • Dipping tobaccos are a form of smokeless tobacco. Dip is occasionally referred to as "chew", and because of this it is commonly confused with chewing tobacco, which encompasses a wider range of products. A small clump of dip is 'pinched' out of the tin and placed between the lower or upper lip and gums. Some brands, as with snus, are portioned in small, porous pouches for less mess.
  • Gutka is a preparation of crushed betel nut, tobacco, and sweet or savory flavorings. It is manufactured in India and exported to a few other countries. A mild stimulant, it is sold across India in small, individual-sized packets.
  • Kreteks are cigarettes made with a complex blend of tobacco, cloves, and a flavoring "sauce". They were first introduced in the 1880s in Kudus, Java, to deliver the medicinal eugenol of cloves to the lungs.
  • Pituri, a nicotine-containing substance traditionally made from Australian tobacco plants, used by Indigenous Australians for chewing and placed between the lower or upper lip and gums.
  • Snus is a steam-pasteurized moist powdered tobacco product that is not fermented and induces minimal salivation. It is consumed by placing it (loose or in little pouches) against the upper gums for an extended period of time. It is somewhat similar to dipping tobacco but does not require spitting and is significantly lower in TSNAs.
  • Tobacco chewing gum A gum containing nicotine or tobacco designed to be chewed.
  • Tobacco edibles, often in the form of an infusion or a spice, have gained popularity in recent years.
  • Tobacco water is a traditional organic insecticide used in domestic gardening. Tobacco dust can be used similarly. It is produced by boiling strong tobacco in water, or by steeping the tobacco in water for a longer period. When cooled, the mixture can be applied as a spray, or painted onto the leaves of garden plants, where it kills insects. Tobacco is, however, banned from use as a pesticide in certified organic production by the USDA's National Organic Program.[83]

Topical

[edit]

Influence

[edit]

Social

[edit]

Smoking in public was, for a long time, reserved for men, and smoking by women was sometimes associated with promiscuity; in Japan, during the Edo period, prostitutes and their clients often approached one another under the guise of offering a smoke. The same was true in 19th-century Europe.[85]

Following the American Civil War, the use of tobacco, primarily in cigars, became associated with masculinity and power. Modern tobacco use has often been stigmatized; this has spawned quitting associations and antismoking campaigns.[86][87] Bhutan is the only country in the world where tobacco sales are illegal.[88] Due to its propensity for causing detumescence and erectile dysfunction, some studies have described tobacco as an anaphrodisiacal substance.[89]

Religion

[edit]

Christianity

[edit]

In Christian denominations of the conservative holiness movement, such as the Allegheny Wesleyan Methodist Connection and Evangelical Wesleyan Church, the use of tobacco and other drugs is prohibited;[90]: 37  ¶42 of the 2014 Book of Discipline of the Allegheny Wesleyan Methodist Connection states:[90][page needed]

In the judgment of The Allegheny Wesleyan Methodist Connection (Original Allegheny Conference), the use of tobacco is a great evil, unbecoming a Christian, a waste of the Lord's money, and a defilement of the body, which should be the temple of the Holy Ghost. We do, therefore, most earnestly require our members to refrain from its cultivation, manufacture, and sale, and to abstain from its use in all forms, for Jesus' sake. We will not receive as members into our churches nor will we ordain or license to preach or to exhort, persons who use, cultivate, manufacture, or sell tobacco. Using tobacco by a member of a church or of the Conference after being received from this date (June 28, 1927) is a violation of the law of the church, and the offending party should be dealt with according to the judiciary rules.[90]: 44 

Members of the Church of Jesus Christ of Latter-day Saints (popularly known as Mormons) adhere to the Word of Wisdom, a religious health code that is interpreted as prohibiting the consumption of tobacco as well as alcohol, coffee, and tea.[91]

Islam

[edit]

Most Islamic scholars have condemned tobacco due to its harmful effects on health. The earliest fatwa (religious opinion) against tobacco use dates from 1602. Most major Islamic sects prohibit its use. While tobacco is not mentioned in the Quran, the Quran does instruct Muslims to live healthy lives.

Sikhism

[edit]

Sikhism, a Dharmic religion from India, considers tobacco consumption as a taboo and very bad for health and spirituality. Initiated Sikhs are never to consume tobacco in any form.[92]

Demographic

[edit]

Research on tobacco use is limited mainly to smoking, which has been studied more extensively than any other form of consumption. An estimated 1.1 billion people, and up to one-third of the adult population, use tobacco in some form.[93] Smoking is more prevalent among men[94] (however, the gender gap declines with age),[95][96] the poor, and in transitional or developing countries.[97] A study published in Morbidity and Mortality Weekly Report found that in 2019 approximately one in four youths (23.0%) in the U.S. had used a tobacco product during the past 30 days. This represented approximately three in 10 high school students (31.2%) and approximately one in eight middle school students (12.5%).[98]

Rates of smoking continue to rise in developing countries, but have leveled off or declined in developed countries.[99] Smoking rates in the United States have dropped by half from 1965 to 2006, falling from 42% to 20.8% in adults.[100] In the developing world, tobacco consumption is rising by 3.4% per year.[101]

Health effects

[edit]
Table from the 2010 DrugScience study ranking various drugs (legal and illegal) based on statements by drug-harm experts. Tobacco was found to be the sixth overall most dangerous drug.[102]

Chemicals

[edit]

Tobacco smoking harms health because of the toxic chemicals in tobacco smoke, including carbon monoxide, cyanide, and carcinogens, which have been proven to cause heart and lung diseases and cancer. Thousands of different substances in cigarette smoke, including polycyclic aromatic hydrocarbons (such as benzopyrene), formaldehyde, cadmium, nickel, arsenic, tobacco-specific nitrosamines, and phenols contribute to the harmful effects of smoking.[103]

According to the World Health Organization, tobacco is the single greatest cause of preventable death globally.[3] WHO estimates that tobacco caused 5.4 million deaths in 2004[104] and 100 million deaths over the course of the 20th century.[3] Similarly, the United States Centers for Disease Control and Prevention describe tobacco use as "the single most important preventable risk to human health in developed countries and an important cause of premature death worldwide."[105] Due to these health consequences, it is estimated that a 10 hectare (approximately 24.7 acre) field of tobacco used for cigarettes causes 30 deaths per year – 10 from lung cancer and 20 from cigarette-induced diseases like cardiac arrest, gangrene, bladder cancer, mouth cancer, etc.[106]

The harms caused by inhaling tobacco smoke include diseases of the heart and lungs, with smoking being a major risk factor for heart attacks, strokes, chronic obstructive pulmonary disease (emphysema), and cancer (particularly cancers of the lungs, larynx, mouth, and pancreas). Cancer is caused by inhaling carcinogenic substances in tobacco smoke.

Inhaling secondhand tobacco smoke (which has been exhaled by a smoker) can cause lung cancer in nonsmoking adults. In the United States, about 3,000 adults die each year due to lung cancer from secondhand smoke exposure. Heart disease caused by secondhand smoke kills around 46,000 nonsmokers every year.[107]

In children, exposure to secondhand tobacco smoke is associated with a higher incidence and severity of respiratory illnesses, middle ear disease, and asthma attacks. Each year in the United States, secondhand smoke exposure causes 24,500 infants to be born with low birthweight, 71,900 preterm births, 202,300 episodes of asthma, and 790,000 health care visits for ear infections.[108]

The addictive alkaloid nicotine is a stimulant, and popularly known as the most characteristic constituent of tobacco. In drug effect preference questionnaires, a rough indicator of addictive potential, nicotine scores almost as highly as opioids.[109] Users typically develop tolerance and dependence.[110][111] Nicotine is known to produce conditioned place preference, a sign of psychological enforcement value.[112] In one medical study, tobacco's overall harm to user and self was determined at three percent below cocaine, and 13 percent above amphetamines, ranking sixth most harmful of the 20 drugs assessed.[113]

Tobacco also contains 2,3,6-Trimethyl-1,4-naphthoquinone (sometimes called 2,3,6-TQ and TMN) which is a reversible monoamine oxidase inhibitor of type A and B with a binding affinity somewhat similar to that of clorgyline and deprenyl. It is a stronger dopamine releasing agent than nicotine and inhibits dopamine metabolism from its MAOI activity. [114][115] Tobacco also contains Harmine and Norharmine which is a reversible MAO-A inhibitor.[116][117][118][119] The MAO-A activity of tobacco alkaloids have been thought to play a role in the addictive qualities of tobacco.[120]

Radioactivity

[edit]

Polonium-210 is a radioactive trace contaminant of tobacco, providing additional explanation for the link between smoking and bronchial cancer.[121] The radioactive particles build up over time in the lungs and a UCLA study has estimated that the radiation from 25 years of smoking would cause over 120 deaths per thousand smokers.[122]

Economic

[edit]

Tobacco makes a significant economic contribution. The global tobacco market in 2010 was estimated at US$760 billion, excluding China.[123] The global revenues from tobacco taxes in 2013–2014 was approximately $269 billion.

In China, cigarette manufacturing is one of the few profitable state-owned industries. For example, in 1998 the 1 429 state-owned enterprises in Yunnan province had revenue of Renminbi (RMB) 69.1 billion (US$8.3 billion) while 8 cigarette manufacturing plants alone accounted for about 53 percent (or RMB 36.2 billion) of total provincial industry sales.[46] The Chinese government also collects tax on tobacco products. Tax revenues from cigarettes increased from 740 to 842 billion Chinese yuan between 2014 and 2016. This generated an additional 101 billion Chinese yuan in tax revenues for the government.[124]

In India, tobacco generates approximately 20 billion Indian rupees (US$0.45 billion) of income per annum as a result of employment, income and government revenue.[125]

Statistica estimates that in the U.S. alone, the tobacco industry has a market of US$121 billion,[126] despite the fact the CDC reports that US smoking rates are declining steadily.[127] In terms of health expenditures, cigarette smoking contributed to more than $225 billion (or 11.7%) of annual healthcare spending in the U.S. in 2014.[128] Smoking-attributable healthcare spending increased more than 30% for Medicaid between 2010 and 2014.[128]

In the US, the decline in the number of smokers, the end of the Tobacco Transition Payment Program in 2014, and competition from growers in other countries, made tobacco farming economics more challenging.[129]

Of the 1.22 billion smokers worldwide, 1 billion of them live in developing or transitional economies, and much of the disease burden and premature mortality attributable to tobacco use disproportionately affect the poor.[97] While smoking prevalence has declined in many developed countries, it remains high in others, and is increasing among women and in developing countries. Between one-fifth and two-thirds of men in most populations smoke. Women's smoking rates vary more widely but rarely equal male rates.[130]

Tobacco users must also spend a significant amount of money on cigarettes to maintain regular use, as tobacco products are often heavily taxed by governments. For example, a pack a day smoker in the state of New York would have to spend around $4,690.25 a year on cigarettes alone.[131]

In Indonesia, the lowest income group spends 15% of its total expenditures on tobacco. In Egypt, more than 10% of low-income household expenditure is on tobacco. The poorest 20% of households in Mexico spend 11% of their income on tobacco.[3]

Advertising

[edit]

The tobacco industry advertises its products through a variety of media, including sponsorship, particularly of sporting events. Because of the health risks of these products, this is now one of the most highly regulated forms of marketing. Some or all forms of tobacco advertising are banned in many countries.[132]

Legality

[edit]

See also

[edit]

References

[edit]
  1. ^ Rudgley R (1998). "Tobacco". The Encyclopaedia of Psychoactive Substances. London: Little, Brown and Company. ISBN 978-0-316-64347-4. OCLC 39129000. Archived from the original on September 27, 2022. Retrieved November 26, 2017.
  2. ^ CDC (August 2, 2023). "What Are the Risk Factors for Lung Cancer?". Retrieved March 31, 2024.
  3. ^ a b c d WHO Report on the Global Tobacco Epidemic 2008 : The MPOWER Package (PDF). World Health Organization. 2008. pp. 6, 8, 20. ISBN 978-92-4-068311-2. OCLC 476167599. Archived from the original (PDF) on January 21, 2022. Retrieved October 6, 2022. Tobacco is the single most preventable cause of death in the world today.
  4. ^ a b Ernst A (1889). "On the etymology of the word tobacco". American Anthropologist. A2 (2): 133–142. doi:10.1525/aa.1889.2.2.02a00020. ISSN 0002-7294.
  5. ^ Hilton R (April 3, 2011). "Christopher Columbus discovers Cuba". World Association of International Studies. Stanford University. Archived from the original on September 1, 2011.
  6. ^ Lane EW (1863). "طُباق". An Arabic-English Lexicon: Derived From the Best and the Most Copious Eastern Sources. Vol. I, Book 5. London: Williams and Norgate. p. 1827. ISBN 978-0-342-25192-6. OCLC 1299308839. Archived from the original on June 22, 2016. Retrieved June 21, 2016.
  7. ^ The word ṭubāq no longer refers to various herbs, but has come to refer, in some dialects, specifically to tobacco. See Wehr H (1979). "طُباق". In Cowan JM (ed.). A Dictionary of Modern Written Arabic (4th ed.). Wiesbaden: Harrassowitz. p. 647. ISBN 978-3-447-02002-2. OCLC 759999696. Archived from the original on June 22, 2016. Retrieved June 21, 2016.{{cite encyclopedia}}: CS1 maint: bot: original URL status unknown (link)
  8. ^ Day A (November 20, 2023). "3 Sisters to Invite to Thanksgiving". Food & Wine.
  9. ^ Goodman, Jordan. Tobacco in History and Culture: An Encyclopedia (Detroit: Thomson Gale, 2005).
  10. ^ Leonard JN (1970). Recipes, Latin American cooking. Time-Life International (Nederlands). p. 21. ISBN 978-0-8094-0063-8.
  11. ^ e.g. Heckewelder, History, Manners and Customs of the Indian Nations who Once Inhabited Pennsylvania, p. 149 ff.
  12. ^ "They smoke with excessive eagerness ... men, women, girls and boys, all find their keenest pleasure in this way." – Dièreville describing the Mi'kmaq, circa 1699 in Port Royal.
  13. ^ {{Ci te book |last=Gottsegen |first=Jack Jacob |title=Tobacco: A Study of Its Consumption in the United States |date=1940 |publisher=Pitman |page=107 |oclc=14728283}}
  14. ^ Cohen K (November 1998). "Native American medicine". Alternative Therapies in Health and Medicine. 4 (6): 45–57. PMID 9810067. ProQuest 204813987.
  15. ^ Appleby J (2010). The Relentless Revolution: A History of Capitalism. W.W. Norton & Company. p. 131.
  16. ^ "Tobacco and slavery : a neverending history". www.medicusmundi.ch (in German). Retrieved July 11, 2024.
  17. ^ Hariot T (1590). A BRIEFE AND TRUE REPORT OF THE NEW FOUND LAND OF VIRGINIA (Report). Project Gutenberg.
  18. ^ Eric Burns, The Smoke of the Gods: A Social History of Tobacco (2006), A popular history focused on the US.
  19. ^ Jordan Goodman, Tobacco in History: The Cultures of Dependence (1993), A scholarly history worldwide.
  20. ^ Charlotte Cosner, The Golden Leaf: How Tobacco Shaped Cuba and the Atlantic World (Vanderbilt University Press; 2015)
  21. ^ Richard Kluger, Ashes to Ashes: America's Hundred-Year Cigarette War (1996)
  22. ^ Allan Brandt, The Cigarette Century: The Rise, Fall, and Deadly Persistence of the Product That Defined America (2007)
  23. ^ Schroeder SA (January 15, 2004). "Tobacco Control in the Wake of the 1998 Master Settlement Agreement". New England Journal of Medicine. 350 (3): 293–301. doi:10.1056/NEJMsr031421. PMID 14715919.
  24. ^ "Interviews – Dr. David Kessler | Inside The Tobacco Deal | Frontline | PBS". www.pbs.org. Retrieved April 20, 2023.
  25. ^ Commissioner Oo (September 9, 2020). "Want to Quit Smoking? FDA-Approved Products Can Help". FDA.
  26. ^ "WHO | WHO Framework Convention on Tobacco Control (WHO FCTC)". Who.int. Archived from the original on May 27, 2008. Retrieved September 18, 2008.
  27. ^ "WHO | WHO Framework Convention on Tobacco Control". WHO. Retrieved February 17, 2021.
  28. ^ Yang H, Ma J (August 2021). "How the COVID-19 pandemic impacts tobacco addiction: Changes in smoking behavior and associations with well-being". Addictive Behaviors. 119: 106917. doi:10.1016/j.addbeh.2021.106917. PMC 9186053. PMID 33862579.
  29. ^ Lewis A (1931). "Tobacco in New Guinea". The American Anthropologist. 33 (1): 134–139. doi:10.1525/aa.1931.33.1.02a00290.
  30. ^ Panter KE, Keeler RF, Bunch TD, Callan RJ (1990). "Congenital skeletal malformations and cleft palate induced in goats by ingestion of Lupinus, Conium and Nicotiana species". Toxicon. 28 (12): 1377–1385. Bibcode:1990Txcn...28.1377P. doi:10.1016/0041-0101(90)90154-Y. PMID 2089736.
  31. ^ Elsey KD, Rabb RL (December 1, 1967). "Biology of the Cabbage Looper on Tobacco In North Carolina1". Journal of Economic Entomology. 60 (6): 1636–1639. doi:10.1093/jee/60.6.1636.
  32. ^ a b c Ryan L, ed. (1995). "Introduction". Post-harvest Tobacco Infestation Control. Norwell, Massachusetts and Dordrecht, Netherlands: Kluwer Academic Publishers. pp. 1–4. doi:10.1007/978-94-017-2723-5_1. ISBN 978-94-017-2723-5.
  33. ^ Garner WW (February 27, 1914). "Tobacco Culture". Farmers' Bulletin (571). United States Department of Agriculture: 3–4. Retrieved March 22, 2020.
  34. ^ Yorktown MA, Us V2. "Tobacco: Colonial Cultivation Methods - Historic Jamestowne Part of Colonial National Historical Park (U.S. National Park Service)". www.nps.gov. Retrieved February 21, 2024.{{cite web}}: CS1 maint: numeric names: authors list (link)
  35. ^ van Willigen J, Eastwood S (2015). Tobacco Culture: Farming Kentucky's Burley Belt. University Press of Kentucky. p. 91. ISBN 978-0-8131-4808-3. Retrieved February 2, 2018.
  36. ^ "USDA/NASS QuickStats Ad-hoc Query Tool". quickstats.nass.usda.gov. 2019. Retrieved July 1, 2020.
  37. ^ Cerami C, Founds H, Nicholl I, Mitsuhashi T, Giordano D, Vanpatten S, Lee A, Al-Abed Y, Vlassara H, Bucala R, Cerami A (1997). "Tobacco smoke is a source of toxic reactive glycation products". Proceedings of the National Academy of Sciences of the United States of America. 94 (25): 13915–20. Bibcode:1997PNAS...9413915C. doi:10.1073/pnas.94.25.13915. PMC 28407. PMID 9391127.
  38. ^ "tobacco curing." The Hutchinson Unabridged Encyclopedia with Atlas and Weather guide. Abington: Helicon, 2010. Credo Reference. Web. September 26, 2012.
  39. ^ a b World Health Organization (2017). Tobacco and its Environmental Impact: An Overview. World Health Organization. ISBN 978-92-4-151249-7. OCLC 988541317. Archived from the original on May 31, 2017.
  40. ^ "Tobacco production". Our World in Data. Retrieved March 7, 2020.
  41. ^ a b c Food and Agriculture Organization of the United Nations. Projection of tobacco production, consumption and trade for the year 2010. (Rome, 2003).
  42. ^ a b The Food and Agriculture Organization of the United Nations. Higher World Tobacco use expected by 2010-growth rates slowing down. (Rome, 2004).
  43. ^ Rowena Jacobs, et al. (2000). "The Supply-Side Effects Of Tobacco Control Policies". In Prabhat Jha, Frank J. Chaloupka (eds.). Tobacco Control in Developing Countries. New York: Oxford University Press. pp. 311ff. ISBN 978-0-19-263250-0.
  44. ^ Hu TW, Mao Z, et al. (2006). "China at the Crossroads: The Economics of Tobacco and Health". Tobacco Control. 15 (Suppl 1): i37–i41. doi:10.1136/tc.2005.014621. PMC 2563551. PMID 16723674.
  45. ^ a b "FAOSTAT". Food And Agriculture Organization of the United Nations. Retrieved May 17, 2020.
  46. ^ a b c d Issues in the global tobacco economy : selected case studies (PDF). United Nations Food and Agriculture Organization. 2003. pp. 2, 39, 43. ISBN 925105083X. OCLC 55056109. Series number 1810-0783. Archived from the original on March 7, 2022. Retrieved October 6, 2022.
  47. ^ "People's Republic of China. "State Tobacco Monopoly Administration". Gov.cn. September 15, 2005. Archived from the original on August 10, 2013. Retrieved October 3, 2013.
  48. ^ "Talking Points, February 3–17, 2010". USC U.S.-China Institute. February 6, 2010. Archived from the original on April 7, 2015.
  49. ^ "Tobacco Board, Guntur". Tobaccoboard.com. Retrieved April 21, 2014.
  50. ^ Shoba, John and Shailesh Vaite. Tobacco and Poverty: Observations from India and Bangladesh. Canada, 2002.
  51. ^ "Tobacco Manufacturing in India".
  52. ^ a b International Tobacco Growers' Association (n.d.). Tobacco farming: sustainable alternatives? Volume 2 (PDF). East Sussex: ITGA. ISBN 978-1-872854-02-1. Archived from the original (PDF) on April 29, 2017. Retrieved July 5, 2016.
  53. ^ Wurth M, Buchanan J (May 13, 2014). Becker J, Ross J, Olugboji B (eds.). Tobacco's Hidden Children Hazardous Child Labor in United States Tobacco Farming. Joe Amon, Zama Coursen-Neff, Arvind Ganesan, Grace Meng. Human Rights Watch. ISBN 978-1-62313-134-0. OCLC 881428758. Archived from the original on August 6, 2015. Retrieved October 6, 2022.
  54. ^ UNICEF (1997). The State of the World's Children 1997 (PDF) (Report). Oxford. ISBN 978-0-19-262871-8. OCLC 36286998. Archived from the original (PDF) on June 9, 2021.
  55. ^ Jaffe ME, Mills M, Rosen SA, Shepard RB, Slavet B, Samet AJ (1995). By the Sweat and Toil of Children. Volume 2. The Use of Child Labor in U.S. Agricultural Imports & Forced and Bonded Child Labor : A Report to the Committee on Appropriations, U.S. Congress (PDF) (Report). Washington, D.C.: International Child Labor Study Group, Bureau of International Labor Affairs, Department of Labor. Archived from the original (PDF) on October 6, 2022.
  56. ^ Bitter Harvest, Child Labour in Agriculture (PDF) (Report). Geneva: International Labour Organization. 1997. Archived from the original (PDF) on October 6, 2022.
  57. ^ Bosch D, Gordon A (August 27–30, 1996). Child Labour in Commercial Agriculture in Africa (Working paper number 3). Subregional technical workshop on child labour in commercial agriculture for selected English-speaking African countries. Dar es Salaam, Tanzania: International Programme on the Elimination of Child Labour, International Labour Organization. ISBN 978-92-2-110485-8. OCLC 36763053.
  58. ^ a b Clacherty G (2009). "Hard work, long hours and little pay: Research with children working on tobacco farms in Malawi". Plan International, Clacherty & Associates Education and Social Development (Pty) Ltd. Archived from the original on October 6, 2022.
  59. ^ England LJ, Bunnell RE, Pechacek TF, Tong VT, McAfee TA (August 2015). "Nicotine and the Developing Human". American Journal of Preventive Medicine. 49 (2): 286–293. doi:10.1016/j.amepre.2015.01.015. PMC 4594223. PMID 25794473.
  60. ^ "International Cigarette Manufacturers," Tobacco Reporter, March 2001
  61. ^ The Campaign for Tobacco Free Kids (November 2001). "Golden Leaf, Barren Harvest: The Costs of Tobacco Farming" (PDF). Archived from the original (PDF) on April 6, 2013.
  62. ^ "Tobacco Underground". The International Consortium of Investigative Journalists. Retrieved November 26, 2012.
  63. ^ a b Taylor P (September 1994). Smoke Ring: The Politics of Tobacco. London: Panos Briefing Paper.
  64. ^ FAO Yearbook, Production, Volume 48. 1995.
  65. ^ National Research Council (US) Committee on Pesticides in the Diets of Infants and Children (1993). "Chapter 8 Estimating the Risks". Pesticides in the Diets of Infants and Children. Washington, D.C.: National Academies Press. p. 341. doi:10.17226/2126. ISBN 978-0-309-04875-0. OCLC 42329648. PMID 25144038.
  66. ^ a b World Health Organization. "Tobacco Free Initiative: Environmental issues". Archived from the original on December 19, 2004.
  67. ^ Ganapathi TR, et al. (2004). "Tobacco (Nicotiana tabacum L.) – A model system for tissue culture interventions and genetic engineering" (PDF). Indian Journal of Biotechnology. 3: 171–184.
  68. ^ Fraley RT, et al. (1983). "Expression of bacterial genes in plant cells". Proc. Natl. Acad. Sci. U.S.A. 80 (15): 4803–4807. Bibcode:1983PNAS...80.4803F. doi:10.1073/pnas.80.15.4803. PMC 384133. PMID 6308651.
  69. ^ "Science of Transgenic Cotton". Cottoncrc.org.au. Archived from the original on March 21, 2012. Retrieved October 3, 2013.
  70. ^ a b James C (1996). "Global Review of the Field Testing and Commercialization of Transgenic Plants: 1986 to 1995" (PDF). The International Service for the Acquisition of Agri-biotech Applications. Retrieved July 17, 2010.
  71. ^ a b c "Tobacco". GMO Compass. Archived from the original on October 2, 2013. Retrieved October 3, 2013.
  72. ^ Conner AJ, Glare TR, Nap JP (January 2003). "The release of genetically modified crops into the environment. Part II. Overview of ecological risk assessment". Plant J. 33 (1): 19–46. doi:10.1046/j.0960-7412.2002.001607.x. PMID 12943539.
  73. ^ Rubin R. "If You Took The Nicotine Out Of Cigarettes, Would Fewer People Want To Smoke?". Forbes. Retrieved May 3, 2019.
  74. ^ Hurt R, Barry JE, Adams AP, Fleming PR (1996), The History of Cardiothoracic Surgery from Early Times, Informa Health Care, p. 120, ISBN 978-1-85070-681-6
  75. ^ Nordenskiold E (1929), "The American Indian as an Inventor", Journal of the Royal Anthropological Institute, 59: 277, doi:10.2307/2843888, JSTOR 2843888
  76. ^ Hurt et al. 1996, p. 120
  77. ^ Nordenskiold 1929, p. 277
  78. ^ Sterling Haynes, MD (December 2012). "Special feature: Tobacco smoke enemas". British Columbia Medical Journal. Doctors of BC. Retrieved March 29, 2019.
  79. ^ "Information Sheet:21 Enemas" (PDF). Information Sheets. Museum of the Royal Pharmaceutical Society, London. Retrieved July 26, 2014.
  80. ^ Tobacco Free Kids (2008). "Bidis: An Overview" (PDF). Tobacco Free Kids. Retrieved October 27, 2021.
  81. ^ American Lung Association. February 2007 An Emerging Deadly Trend: Waterpipe Tobacco Use Archived January 2, 2014, at the Wayback Machine
  82. ^ "Generic Materials Search | Organic Materials Review Institute". Omri.org. Archived from the original on July 23, 2015. Retrieved October 3, 2014.
  83. ^ Sparks B. "Stinging and Biting Pests of People". Archived from the original on February 14, 2007. Extension Entomologist of the University of Georgia College of Agricultural & Environmental Sciences Cooperative Extension Service.
  84. ^ Gilman & Zhou 2004, p. 92–99.
  85. ^ Durkin S, Brennan E, Wakefield M (2012). "Mass media campaigns to promote smoking cessation among adults: an integrative review" (PDF). Tobacco Control. 21 (2): 127–138. doi:10.1136/tobaccocontrol-2011-050345. PMID 22345235. S2CID 3053297.
  86. ^ Mullin Sandra (2011). "Global anti-smoking campaigns urgently needed". The Lancet. 378 (9795): 970–971. doi:10.1016/s0140-6736(11)61058-1. PMID 21741699. S2CID 7532790.
  87. ^ Weiner E (January 20, 2005). "The First Nonsmoking Nation". Slate.com. Retrieved October 23, 2019.
  88. ^ Verze P, Margreiter M, Esposito K, Montorsi P, Mulhall J (2015). "The Link Between Cigarette Smoking and Erectile Dysfunction: A Systematic Review". European Urology Focus. 1 (1): 39–46. doi:10.1016/j.euf.2015.01.003. PMID 28723353.
  89. ^ a b c The Discipline of the Allegheny Wesleyan Methodist Connection (Original Allegheny Conference). Salem: Allegheny Wesleyan Methodist Connection. 2014.
  90. ^ Stack PF (August 31, 2012). "It's Official: Coke and Pepsi are OK for Mormons". Washington Post. (Religion News Service). Archived from the original on March 27, 2013. Retrieved September 20, 2013..
  91. ^ Dhillon BS (n.d.). "Sikhs and Smoking".
  92. ^ Gilman & Zhou 2004, p. 26.
  93. ^ "Guindon & Boisclair" 2004, pp. 13–16.
  94. ^ Samet & Yoon 2001, p. 5-6.
  95. ^ Surgeon General's Report Women and Smoking 2001, p. 47.
  96. ^ a b "WHO/WPRO-Tobacco". World Health Organization Regional Office for the Western Pacific. 2005. Archived from the original on February 11, 2009. Retrieved January 1, 2009.
  97. ^ Wang TW, Gentzke AS, Creamer MR, Cullen KA, Holder-Hayes E, Sawdey MD, Anic GM, Portnoy DB, Hu S, Homa DM, Jamal A, Neff LJ (November 6, 2019). "Tobacco Product Use and Associated Factors Among Middle and High School Students — United States, 2019". MMWR. Surveillance Summaries. 68 (12): 1–22. doi:10.15585/mmwr.ss6812a1. PMC 6903396. PMID 31805035.
  98. ^ "Who Fact Sheet: Tobacco". Who.int. July 26, 2013. Retrieved October 3, 2013.
  99. ^ "Cigarette Smoking Among Adults – United States, 2006". Cdc.gov. Retrieved October 3, 2013.
  100. ^ "WHO/WPRO-Smoking Statistics". Wpro.who.int. May 27, 2002. Archived from the original on August 26, 2013. Retrieved April 21, 2014.
  101. ^ Nutt DJ, King LA, Phillips LD (November 2010). "Drug harms in the UK: a multicriteria decision analysis". Lancet. 376 (9752): 1558–1565. CiteSeerX 10.1.1.690.1283. doi:10.1016/S0140-6736(10)61462-6. PMID 21036393. S2CID 5667719.
  102. ^ Proctor Robert N (2012). "The history of the discovery of the cigarette-lung cancer link: evidentiary traditions, corporate denial, global toll" (PDF). Tobacco Control. 21 (2): 87–91. doi:10.1136/tobaccocontrol-2011-050338. PMID 22345227. S2CID 2734836.
  103. ^ Mathers C, Boerma T, Fat DM (2008). The Global Burden of Disease : 2004 Update (PDF). World Health Organization. hdl:10665/43942. ISBN 978-92-4-156371-0. OCLC 264018380. Archived from the original on February 7, 2022. Retrieved October 6, 2022.
  104. ^ "Nicotine: A Powerful Addiction". Centers for Disease Control and Prevention. Archived from the original on February 26, 2009.
  105. ^ Proctor RN (March 2012). "The history of the discovery of the cigarette–lung cancer link: evidentiary traditions, corporate denial, global toll: Table 1". Tobacco Control. 21 (2): 87–91. doi:10.1136/tobaccocontrol-2011-050338. PMID 22345227.
  106. ^ "Secondhand Smoke". BeTobaccoFree. Health and Human Services. Archived from the original on September 20, 2014.
  107. ^ Air Resources Board (June 24, 2005). Proposed Identification of Environmental Tobacco Smoke as a Toxic Air Contaminant (PDF) (Report). California Environmental Protection Agency. Archived from the original on November 27, 2021. Retrieved October 6, 2022.
  108. ^ Fischman MW, Mello NK, eds. (1989). Testing for Abuse Liability of Drugs in Humans (PDF). Rockville, MD: National Institute on Drug Abuse, Health and Human Services. p. 79. NIDA Research Monograph No. 92. Archived from the original (PDF) on December 22, 2016.
  109. ^ "Tobacco Facts – Why is Tobacco So Addictive?". Tobaccofacts.org. Archived from the original on March 14, 2007. Retrieved September 18, 2008.
  110. ^ "Philip Morris Information Sheet". Stanford University. Archived from the original on April 5, 2008. Retrieved September 18, 2008.
  111. ^ Le Foll B, Goldberg SR (April 2005). "Nicotine induces conditioned place preferences over a large range of doses in rats". Psychopharmacology. 178 (4): 481–492. doi:10.1007/s00213-004-2021-5. PMID 15765262. S2CID 34966899.
  112. ^ Nutt DJ, King LA, Phillips LD (November 2010). "Drug harms in the UK: a multicriteria decision analysis". The Lancet. 376 (9752): 1558–1565. CiteSeerX 10.1.1.690.1283. doi:10.1016/S0140-6736(10)61462-6. PMID 21036393. S2CID 5667719.
  113. ^ McAfee G (March 25, 2024). Smoking and brain dopaminergic neurochemistry (Thesis). North-West University.
  114. ^ "1,4-Naphthalenedione, 2,3,6-trimethyl-".
  115. ^ Salahshoor MR, Roshankhah S, Motavalian V, Jalili C (2019). "Effect of Harmine on Nicotine-Induced Kidney Dysfunction in Male Mice". International Journal of Preventive Medicine. 10: 97. doi:10.4103/ijpvm.IJPVM_85_18. PMC 6592107. PMID 31360344.
  116. ^ Truman P, Grounds P, Brennan KA (2017). "Monoamine oxidase inhibitory activity in tobacco particulate matter: Are harman and norharman the only physiologically relevant inhibitors?". Neurotoxicology. 59: 22–26. Bibcode:2017NeuTx..59...22T. doi:10.1016/j.neuro.2016.12.010. PMID 28057462.
  117. ^ Ding Z, Li X, Chen H, Hou H, Hu Q (2022). "Harmane Potentiates Nicotine Reinforcement Through MAO-A Inhibition at the Dose Related to Cigarette Smoking". Frontiers in Molecular Neuroscience. 15. doi:10.3389/fnmol.2022.925272. PMC 9271706. PMID 35832393.
  118. ^ Janiger O, De Rios MD (March 25, 1976). "Nicotiana an Hallucinogen?". Economic Botany. 30 (2): 149–151. Bibcode:1976EcBot..30..149J. doi:10.1007/BF02862960. JSTOR 4253715.
  119. ^ Bacher I, Houle S, Xu X, Zawertailo L, Soliman A, Wilson AA, Selby P, George TP, Sacher J, Miler L, Kish SJ, Rusjan P, Meyer JH (2011). "Monoamine Oxidase a Binding in the Prefrontal and Anterior Cingulate Cortices During Acute Withdrawal from Heavy Cigarette Smoking". Archives of General Psychiatry. 68 (8): 817–826. doi:10.1001/archgenpsychiatry.2011.82. PMID 21810646.
  120. ^ Radford EP, Hunt VR (1964). "Polonium-210: A Volatile Radioelement in Cigarettes". Science. 143 (3603): 247–249. Bibcode:1964Sci...143..247R. doi:10.1126/science.143.3603.247. JSTOR 1712451. PMID 14078362. S2CID 23455633.
  121. ^ "Big Tobacco knew radioactive particles in cigarettes posed cancer risk but kept quiet". www.uclahealth.org.
  122. ^ "British American Tobacco – The global market". www.bat.com. Archived from the original on March 10, 2018. Retrieved March 15, 2018.
  123. ^ Goodchild M, Zheng R (July 1, 2018). "Early assessment of China's 2015 tobacco tax increase". Bulletin of the World Health Organization. 96 (7): 506–512. doi:10.2471/BLT.17.205989 (inactive December 5, 2024). PMC 6022610. PMID 29962553.{{cite journal}}: CS1 maint: DOI inactive as of December 2024 (link)
  124. ^ "TOBACCO IN INDIA: 4.10 ECONOMIC SIGNIFICANCE OF TOBACCO". Food and Agriculture Organization (FAO). Retrieved October 27, 2021.
  125. ^ "Tobacco: U.S. market value 2012–2017 | Statistic". Statista. Retrieved March 15, 2018.
  126. ^ Health CO. "CDC – Trends in Current Cigarette Smoking – Smoking & Tobacco Use". Smoking and Tobacco Use. Archived from the original on March 7, 2018. Retrieved March 15, 2018.
  127. ^ a b Xu X, Shrestha SS, Trivers KF, Neff L, Armour BS, King BA (September 2021). "U.S. healthcare spending attributable to cigarette smoking in 2014". Preventive Medicine. 150: 106529. doi:10.1016/j.ypmed.2021.106529. PMC 10953804. PMID 33771566.
  128. ^ Bomey N (September 2, 2015). "Thousands of farmers stopped growing tobacco after deregulation payouts". USA Today.
  129. ^ "Tobacco: Active and Passive Smoking". Greenfacts.org. Retrieved July 5, 2016.
  130. ^ "Cost of Smoking". Tobacco-Free Life. Retrieved July 6, 2022.
  131. ^ Products Cf (January 28, 2022). "Advertising and Promotion". FDA. Retrieved July 6, 2022.

Further reading

[edit]
  • Werner, Carl Avery. Tobaccoland: A book about tobacco; its history, legends, literature, cultivation, social and hygienic influences, commercial development, industrial processes and governmental regulation. (1922) online
[edit]