2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming): Difference between revisions
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{{Short description|Class of enzymes}} |
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{{Infobox enzyme |
{{Infobox enzyme |
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| Name = 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) |
| Name = 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) |
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| EC_number = 1.14.11.34 |
| EC_number = 1.14.11.34 |
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| IUBMB_EC_number = 1/14/11/34 |
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'''2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)''' ({{EC number|1.14.11.34}}, ''ethylene-forming enzyme'', ''EFE'') is an [[enzyme]] with |
'''2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)''' ({{EC number|1.14.11.34}}, ''ethylene-forming enzyme'', ''EFE'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''L-arginine,2-oxoglutarate:oxygen oxidoreductase (succinate-forming)''.<ref>{{cite journal | vauthors = Nagahama K, Ogawa T, Fujii T, Tazaki M, Tanase S, Morino Y, Fukuda H | title = Purification and properties of an ethylene-forming enzyme from Pseudomonas syringae pv. phaseolicola PK2 | journal = Journal of General Microbiology | volume = 137 | issue = 10 | pages = 2281–6 | date = October 1991 | pmid = 1770346 | doi = 10.1099/00221287-137-10-2281 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Fukuda H, Ogawa T, Tazaki M, Nagahama K, Fujii T, Tanase S, Morino Y | title = Two reactions are simultaneously catalyzed by a single enzyme: the arginine-dependent simultaneous formation of two products, ethylene and succinate, from 2-oxoglutarate by an enzyme from Pseudomonas syringae | journal = Biochemical and Biophysical Research Communications | volume = 188 | issue = 2 | pages = 483–9 | date = October 1992 | pmid = 1445291 | doi = 10.1016/0006-291X(92)91081-Z }}</ref><ref>{{cite journal | vauthors = Fukuda H, Ogawa T, Ishihara K, Fujii T, Nagahama K, Omata T, Inoue Y, Tanase S, Morino Y | title = Molecular cloning in Escherichia coli, expression, and nucleotide sequence of the gene for the ethylene-forming enzyme of Pseudomonas syringae pv. phaseolicola PK2 | journal = Biochemical and Biophysical Research Communications | volume = 188 | issue = 2 | pages = 826–32 | date = October 1992 | pmid = 1445325 | doi = 10.1016/0006-291X(92)91131-9 }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]] |
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: [[2-oxoglutarate]] + L-[[arginine]] + O<sub>2</sub> <math>\rightleftharpoons</math> [[succinate]] + CO<sub>2</sub> + [[guanidine]] + (S)-1-pyrroline-5-carboxylate + H<sub>2</sub>O (overall reaction) |
: [[2-oxoglutarate]] + L-[[arginine]] + O<sub>2</sub> <math>\rightleftharpoons</math> [[succinate]] + CO<sub>2</sub> + [[guanidine]] + (S)-1-pyrroline-5-carboxylate + H<sub>2</sub>O (overall reaction) |
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== External links == |
== External links == |
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*{{MeshName|2-oxoglutarate/L-arginine+monooxygenase/decarboxylase+(succinate-forming)}} |
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{{Dioxygenases}} |
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{{Enzymes}} |
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{{Portal bar|Biology|border=no}} |
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[[Category:EC 1.14.11]] |
[[Category:EC 1.14.11]] |
Latest revision as of 12:30, 26 August 2023
2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) | |||||||||
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Identifiers | |||||||||
EC no. | 1.14.11.34 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) (EC 1.14.11.34, ethylene-forming enzyme, EFE) is an enzyme with systematic name L-arginine,2-oxoglutarate:oxygen oxidoreductase (succinate-forming).[1][2][3] This enzyme catalyses the following chemical reaction
- 2-oxoglutarate + L-arginine + O2 succinate + CO2 + guanidine + (S)-1-pyrroline-5-carboxylate + H2O (overall reaction)
- (1a) 2-oxoglutarate + L-arginine + O2 succinate + CO2 + L-hydroxyarginine
- (1b) L-hydroxyarginine guanidine + (S)-1-pyrroline-5-carboxylate + H2O
2-oxoglutarate/L-arginine monooxygenase/decarboxylase catalyses two cycles of the ethylene-forming reaction.
References
[edit]- ^ Nagahama K, Ogawa T, Fujii T, Tazaki M, Tanase S, Morino Y, Fukuda H (October 1991). "Purification and properties of an ethylene-forming enzyme from Pseudomonas syringae pv. phaseolicola PK2". Journal of General Microbiology. 137 (10): 2281–6. doi:10.1099/00221287-137-10-2281. PMID 1770346.
- ^ Fukuda H, Ogawa T, Tazaki M, Nagahama K, Fujii T, Tanase S, Morino Y (October 1992). "Two reactions are simultaneously catalyzed by a single enzyme: the arginine-dependent simultaneous formation of two products, ethylene and succinate, from 2-oxoglutarate by an enzyme from Pseudomonas syringae". Biochemical and Biophysical Research Communications. 188 (2): 483–9. doi:10.1016/0006-291X(92)91081-Z. PMID 1445291.
- ^ Fukuda H, Ogawa T, Ishihara K, Fujii T, Nagahama K, Omata T, Inoue Y, Tanase S, Morino Y (October 1992). "Molecular cloning in Escherichia coli, expression, and nucleotide sequence of the gene for the ethylene-forming enzyme of Pseudomonas syringae pv. phaseolicola PK2". Biochemical and Biophysical Research Communications. 188 (2): 826–32. doi:10.1016/0006-291X(92)91131-9. PMID 1445325.
External links
[edit]- 2-oxoglutarate/L-arginine+monooxygenase/decarboxylase+(succinate-forming) at the U.S. National Library of Medicine Medical Subject Headings (MeSH)