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{{Short description|Class of enzymes}}
{{Infobox enzyme
{{Infobox enzyme
| Name = 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)
| Name = 2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)
| EC_number = 1.14.11.34
| EC_number = 1.14.11.34
| CAS_number =
| CAS_number =
| GO_code =
| IUBMB_EC_number = 1/14/11/34
| GO_code =
| image =
| image =
| width =
| width =
| caption =
| caption =
}}
}}
'''2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)''' ({{EC number|1.14.11.34}}, ''ethylene-forming enzyme'', ''EFE'') is an [[enzyme]] with system name ''L-arginine,2-oxoglutarate:oxygen oxidoreductase (succinate-forming)''.<ref>{{cite journal | title = Purification and properties of an ethylene-forming enzyme from <em>Pseudomonas syringae</em> pv. <em>phaseolicola</em> PK2 |author = Nagahama, K., Ogawa, T., Fujii, T., Tazaki, M., Tanase, S., Morino, Y. and Fukuda, H. |journal = J. Gen. Microbiol. |date = 1991 |volume = 137 |pages = 2281-2286 |pmid = 1770346}}</ref><ref>{{cite journal | title = Two reactions are simultaneously catalyzed by a single enzyme: the arginine-dependent simultaneous formation of two products, ethylene and succinate, from 2-oxoglutarate by an enzyme from <em>Pseudomonas syringae</em> |author = Fukuda, H., Ogawa, T., Tazaki, M., Nagahama, K., Fujii, T., Tanase, S. and Morino, Y. |journal = Biochem. Biophys. Res. Commun. |date = 1992 |volume = 188 |pages = 483-489 |pmid = 1445291}}</ref><ref>{{cite journal | title = Molecular cloning in <em>Escherichia coli</em>, expression, and nucleotide sequence of the gene for the ethylene-forming enzyme of <em>Pseudomonas syringae</em> pv. <em>phaseolicola</em> PK2 |author = Fukuda, H., Ogawa, T., Ishihara, K., Fujii, T., Nagahama, K., Omata, T., Inoue, Y., Tanase, S. and Morino, Y. |journal = Biochem. Biophys. Res. Commun. |date = 1992 |volume = 188 |pages = 826-832 |pmid = 1445325}}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]
'''2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)''' ({{EC number|1.14.11.34}}, ''ethylene-forming enzyme'', ''EFE'') is an [[enzyme]] with [[List of enzymes|systematic name]] ''L-arginine,2-oxoglutarate:oxygen oxidoreductase (succinate-forming)''.<ref>{{cite journal | vauthors = Nagahama K, Ogawa T, Fujii T, Tazaki M, Tanase S, Morino Y, Fukuda H | title = Purification and properties of an ethylene-forming enzyme from Pseudomonas syringae pv. phaseolicola PK2 | journal = Journal of General Microbiology | volume = 137 | issue = 10 | pages = 2281–6 | date = October 1991 | pmid = 1770346 | doi = 10.1099/00221287-137-10-2281 | doi-access = free }}</ref><ref>{{cite journal | vauthors = Fukuda H, Ogawa T, Tazaki M, Nagahama K, Fujii T, Tanase S, Morino Y | title = Two reactions are simultaneously catalyzed by a single enzyme: the arginine-dependent simultaneous formation of two products, ethylene and succinate, from 2-oxoglutarate by an enzyme from Pseudomonas syringae | journal = Biochemical and Biophysical Research Communications | volume = 188 | issue = 2 | pages = 483–9 | date = October 1992 | pmid = 1445291 | doi = 10.1016/0006-291X(92)91081-Z }}</ref><ref>{{cite journal | vauthors = Fukuda H, Ogawa T, Ishihara K, Fujii T, Nagahama K, Omata T, Inoue Y, Tanase S, Morino Y | title = Molecular cloning in Escherichia coli, expression, and nucleotide sequence of the gene for the ethylene-forming enzyme of Pseudomonas syringae pv. phaseolicola PK2 | journal = Biochemical and Biophysical Research Communications | volume = 188 | issue = 2 | pages = 826–32 | date = October 1992 | pmid = 1445325 | doi = 10.1016/0006-291X(92)91131-9 }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]]


: [[2-oxoglutarate]] + L-[[arginine]] + O<sub>2</sub> <math>\rightleftharpoons</math> [[succinate]] + CO<sub>2</sub> + [[guanidine]] + (S)-1-pyrroline-5-carboxylate + H<sub>2</sub>O (overall reaction)
: [[2-oxoglutarate]] + L-[[arginine]] + O<sub>2</sub> <math>\rightleftharpoons</math> [[succinate]] + CO<sub>2</sub> + [[guanidine]] + (S)-1-pyrroline-5-carboxylate + H<sub>2</sub>O (overall reaction)
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== External links ==
== External links ==
* {{MeshName|2-oxoglutarate/L-arginine+monooxygenase/decarboxylase+(succinate-forming)}}
*{{MeshName|2-oxoglutarate/L-arginine+monooxygenase/decarboxylase+(succinate-forming)}}

{{Dioxygenases}}
{{Enzymes}}
{{Portal bar|Biology|border=no}}


[[Category:EC 1.14.11]]
[[Category:EC 1.14.11]]

Latest revision as of 12:30, 26 August 2023

2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming)
Identifiers
EC no.1.14.11.34
Databases
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2-oxoglutarate/L-arginine monooxygenase/decarboxylase (succinate-forming) (EC 1.14.11.34, ethylene-forming enzyme, EFE) is an enzyme with systematic name L-arginine,2-oxoglutarate:oxygen oxidoreductase (succinate-forming).[1][2][3] This enzyme catalyses the following chemical reaction

2-oxoglutarate + L-arginine + O2 succinate + CO2 + guanidine + (S)-1-pyrroline-5-carboxylate + H2O (overall reaction)
(1a) 2-oxoglutarate + L-arginine + O2 succinate + CO2 + L-hydroxyarginine
(1b) L-hydroxyarginine guanidine + (S)-1-pyrroline-5-carboxylate + H2O

2-oxoglutarate/L-arginine monooxygenase/decarboxylase catalyses two cycles of the ethylene-forming reaction.

References

[edit]
  1. ^ Nagahama K, Ogawa T, Fujii T, Tazaki M, Tanase S, Morino Y, Fukuda H (October 1991). "Purification and properties of an ethylene-forming enzyme from Pseudomonas syringae pv. phaseolicola PK2". Journal of General Microbiology. 137 (10): 2281–6. doi:10.1099/00221287-137-10-2281. PMID 1770346.
  2. ^ Fukuda H, Ogawa T, Tazaki M, Nagahama K, Fujii T, Tanase S, Morino Y (October 1992). "Two reactions are simultaneously catalyzed by a single enzyme: the arginine-dependent simultaneous formation of two products, ethylene and succinate, from 2-oxoglutarate by an enzyme from Pseudomonas syringae". Biochemical and Biophysical Research Communications. 188 (2): 483–9. doi:10.1016/0006-291X(92)91081-Z. PMID 1445291.
  3. ^ Fukuda H, Ogawa T, Ishihara K, Fujii T, Nagahama K, Omata T, Inoue Y, Tanase S, Morino Y (October 1992). "Molecular cloning in Escherichia coli, expression, and nucleotide sequence of the gene for the ethylene-forming enzyme of Pseudomonas syringae pv. phaseolicola PK2". Biochemical and Biophysical Research Communications. 188 (2): 826–32. doi:10.1016/0006-291X(92)91131-9. PMID 1445325.
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