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{{Short description|British biotechnology company}}
{{EngvarB|date=May 2014}}
{{EngvarB|date=May 2014}}
{{Use dmy dates|date=May 2014}}
{{Use dmy dates|date=May 2014}}
{{Infobox company
{{Infobox company
| name = Abcam PLC
| name = Abcam Limited
| logo = [[Image:Abcam Logo.png|220px|Abcam]]
| logo = Abcam logo.svg
| former_name = {{Ubl
| type = Public company
| Abcam Limited (1998{{endash}}2005)
| traded_as = {{LSE|ABC}}
| Abcam plc (2005{{endash}}2023)<ref name="CompaniesHouse" />
⚫
| foundation = 1998
| location_city =
| key_people = Jonathan Milner CE-Ho
⚫
| industry = [[Biotech]], [[Life sciences]]
⚫
| products = [[Antibody|Research antibodies]], kits and assays for biological research
⚫
| divisions =
⚫
| revenue = {{profit}} £97.8m (''2012'')<ref name="Abcam Annual report 2012">{{Cite web | title=Abcam 2012 Annual Report | url= http://www.abcamplc.com/ps/downloads/Abcam2012R.pdf | publisher=Abcam PLC | date=September 2012 | accessdate=19 November 2012}}</ref>
| operating_income =
⚫
| net_income = {{profit}} £38.6m (''2012'')<ref name="Abcam Annual report 2012" />
⚫
| num_employees = > 650 (''2012'')<ref name="Abcam Annual report 2012" />
⚫
| subsid =
| homepage = {{URL|www.abcam.com}}
| intl = yes
}}
}}
| type = [[Subsidiary]]
'''Abcam plc''' is a global [[Biotechnology|biotech]] company based in the [[Cambridge Science Park]] in [[Cambridge]], England, with offices in [[Cambridge, Massachusetts|Cambridge, Massachusetts, United States]], San Francisco, Hong Kong, Shanghai, and Tokyo.
| traded_as = {{Unbulleted list|{{AIM was|ABC}}|{{NASDAQ was|ABCM}}}}
| founders = {{Unbulleted list|Jonathan Milner| [[Tony Kouzarides]]| [[David Cleevely]]}}
| key_people = Markus Lusser ([[President (corporate title)|president]])
⚫
| industry = {{Unbulleted list|[[Biotechnology]]| [[Life sciences]]}}
| products = {{Ubl
| [[Antibody|Research antibodies]]
⚫
| Kits and assays for biological research
}}
⚫
| revenue = {{profit}} £361.7 million (2022)<ref name="Abcam Annual report 2022">{{Cite web | title=Abcam 2022 Annual Report (Form 20-F) | url= https://www.sec.gov/ix?doc=/Archives/edgar/data/0001492074/000119312523074408/d433862d20f.htm | publisher=US Securities and Exchange Commission | date=20 March 2023 | accessdate=12 August 2023}}</ref>
| operating_income = {{decrease}} £(10.1) million (2022)<ref name="Abcam Annual report 2022" />
⚫
| net_income = {{decrease}} £(8.5) million (2022)<ref name="Abcam Annual report 2022" />
| assets = {{increase}} £1,057 million (2022)<ref name="Abcam Annual report 2022" />
| equity = {{increase}} £726.9 million (2022)<ref name="Abcam Annual report 2022" />
⚫
| num_employees = 1,760 (2022)<ref name="Abcam Annual report 2022" />
⚫
| divisions =
⚫
| subsid =
| homepage = {{Unbulleted list|{{URL|abcam.com}}| {{URL|abcamplc.com}}}}
⚫
| foundation = {{Start date and age|1998}}
| hq_location = [[Cambridge Biomedical Campus]]
| hq_location_city = [[Cambridge]]
| hq_location_country = UK
| parent = {{ubl|[[Danaher Corporation]] (2023–present)}}
}}
'''Abcam Limited'''<ref name="CompaniesHouse">{{Cite web |date=1998-02-12 |title=Abcam Limited overview - Find and update company information - GOV.UK |url=https://find-and-update.company-information.service.gov.uk/company/03509322 |access-date=2024-02-13 |website=[[Companies House]] |language=en}}</ref> is a producer, distributor and seller of protein research tools operating worldwide from 13 locations with 1,800 employees of which 400 work in Research and Development (R&D). Abcam was listed on the [[Nasdaq]]<ref>{{Cite web|title = ABCAM share price (ABCM) - Nasdaq|url = https://www.nasdaq.com/market-activity/stocks/abcm/real-time}}</ref> and the [[London Stock Exchange]] until it was acquired by [[Danaher Corporation]] in 2023.<ref>{{cite web |url=https://www.contractpharma.com/contents/view_breaking-news/2023-12-06/danaher-completes-57b-acquisition-of-abcam/ |title=Danaher Completes $5.7B Acquisition of Abcam |publisher= Contract Pharma |date=December 6, 2023}}</ref>


==History==
==History==
The premise of the company was incubated from a laboratory in the [[University of Cambridge]], UK in 1998. The principal founder Jonathan Milner was working as a [[Postdoctoral research]]er studying the newly discovered breast cancer protein [[BRCA2]] in Professor [[Tony Kouzarides]]' laboratory. The project slowed because of problems finding quality antibody reagents that had honest and up to date information about their uses and limitations. This scenario provided the motivation to form an on-line service, that would help themselves and researchers across the globe.
The company was founded in 1998 by Jonathan Milner with co-founders professor [[Tony Kouzarides]] and [[David Cleevely]], with the idea of making it easier for research scientists to buy antibodies across the web.<ref>{{Cite web|url=http://www.businessinsider.com/abcam-the-next-giant-of-the-life-sciences-2011-5?IR=T|title=Abcam - the next giant of the Life Sciences?|website=Business Insider|access-date=2016-06-16}}</ref> Milner was a [[postdoctoral research]]er studying the newly discovered breast cancer protein [[BRCA2]] in Kouzarides' [[University of Cambridge|Cambridge University]] laboratory. The project had slowed because of problems finding quality antibody reagents that had honest and up-to-date information about their uses and limitations. This scenario provided the motivation to form an on-line service that would help themselves and researchers across the globe.<ref>{{Cite web|url=http://www.abcamplc.com/story.html|title=Abcam plc investor relations - Abcam story|website=www.abcamplc.com|access-date=2016-06-16|archive-date=8 June 2016|archive-url=https://web.archive.org/web/20160608111739/http://www.abcamplc.com/story.html|url-status=dead}}</ref>


Since its inception in 1998, the company has diversified from carrying only antibodies. It supplies antibody related products such as immunoassays (e.g. SimpleStep ELISA Kits), peptides, proteins and protein detection products (e.g. immunohistochemistry (IHC) staining kits). Abcam also has a portfolio of non-antibody related products such as biochemicals, cellular assays, and epigenetics kits (e.g. FirePlex Multiplex miRNA Kits).
The company was founded by [[David Cleevely]], Jonathan Milner, and [[Tony Kouzarides]] in 1998, and has become one of the largest retailers of research [[antibodies]] in the world{{Citation needed|date=March 2009}}. Kouzarides invented the name, which is a [[portmanteau]] of antibody (ab) and Cambridge (cam). The idea was that Abcam would not only sell antibodies, but provide a high degree of scientific information and characterisation information associated with each antibody, such as [[Western blot]] images, and [[Immunohistochemical staining|immunohistochemistry]].


On 28 August 2023, [[Danaher Corporation]] announced that it had entered into a definitive agreement to acquire Abcam for approximately $5.7 billion at $24 per share in cash.<ref>{{Cite web |last=Mishra |first=Manas |date=August 28, 2023 |title=Danaher to buy Abcam in deal valued at $5.7 billion |url=https://www.nasdaq.com/articles/danaher-to-buy-abcam-in-deal-valued-at-$5.7-billion |access-date=August 28, 2023 |website=Nasdaq}}</ref><ref>{{Cite web |date=2023-08-28 |title=Danaher to Acquire Abcam |url=https://www.life-sciences-europe.com/news/danaher-acquire-abcam-corporation-nyse-dhr-group-plc-2001-121906.html |access-date=2023-09-27 |website=Life Sciences Europe}}</ref><ref>{{Cite web |date=2023-08-28 |title=Danaher to Acquire Abcam - Aug 28, 2023 |url=https://www.danaher.com/styles,%20https://investors.danaher.com/2023-08-28-Danaher-to-Acquire-Abcam |access-date=2023-08-28 |website=www.danaher.com |language=en}}</ref> The acquisition was completed on December 6.<ref>{{Cite web|url=https://www.prnewswire.com/news-releases/danaher-completes-acquisition-of-abcam-302007456.html|title=Danaher Completes Acquisition of Abcam|work=PR Newswire|access-date=2023-12-12|language=en-US}}</ref>
Since its inception in 1998, the company has diversified from carrying only antibodies and now supplies antibody-related products such as [[peptides]] and equipment.


⚫
==Acquisitions==
Abcam is a [[life-science]] [[e-commerce]] company which facilitates public customer feedback on products
⚫
In May 2011, Abcam announced the acquisition of MitoSciences, a privately held biotech company based in Eugene, Oregon (US).<ref name="mito">{{Cite news|title = Abcam Completes $6M Takeover of Mitochondrial Research Tools Specialist MitoSciences|url = http://www.genengnews.com/gen-news-highlights/abcam-completes-6m-takeover-of-mitochondrial-research-tools-specialist-mitosciences/81245198/|newspaper = Genetic Engineering & Biology News|date = 2011-05-24|access-date = 2015-12-21}}</ref> The company produced and distributed [[immunoassay]] platforms and high performance monoclonal antibodies. It was founded in 2004 with the mission of advancing mitochondrial research and developing products that support critical research in cancer, [[neurodegeneration]], and [[metabolic disorders]].
using reviews and ratings which customers can submit. This has given rise to the nickname "the [[Amazon.com|Amazon]] of antibodies"<ref>{{Cite web | title=Midas Extra share tips: Abcam & Vectura | url= http://www.thisismoney.co.uk/news/columnists/article.html?in_article_id=475009&in_page_id=19&in_author_id=1822 | publisher=This Is Money | date=1 February 2009| accessdate=9 March 2009}}</ref><ref>{{Cite web | title=Babraham to spin out antibody tyro | url= http://www.businessweekly.co.uk/2008031931640/life-sciences-archive/babraham-to-spin-out-antibody-tyro.html |work=Business Weekly | date=19 March 2008 | accessdate=9 March 2009}} {{Dead link|date=October 2010|bot=H3llBot}}</ref>


On 12 September 2011, Abcam completed the purchase of Ascent Scientific. Ascent Scientific was a company based in Bristol, United Kingdom that provided high-quality biochemical products that modulate the function of proteins for use in life science research. After outsourcing biochemical production, the Bristol site and manufacturing facilities were closed in 2017.<ref>{{Cite web|url=https://uploads.abcamplc.com/wp-content/uploads/2018/03/02195303/Abcam-plc-H1-2018-Interim-Report.pdf|title=Abcam H1 2018 Interim Report|last=|first=|date=|website=www.abcamplc.com|archive-url=https://web.archive.org/web/20180510051642/https://uploads.abcamplc.com/wp-content/uploads/2018/03/02195303/Abcam-plc-H1-2018-Interim-Report.pdf|archive-date=10 May 2018|access-date=2018-05-09|url-status=dead}}</ref>
Abcam is also listed on the [[London Stock Exchange]].


⚫
On 19 April 2012, Abcam completed the purchase of Epitomics. Epitomics was a privately held biotech company in Burlingame, California (US) and Hangzhou (China) that focused on the development, production, and distribution of rabbit [[monoclonal antibodies]] for biomedical research and diagnostic applications.<ref>{{Cite web|title = Abcam to buy Epitomics of San Francisco for $170M|url = http://www.marketwatch.com/story/abcam-to-buy-epitomics-of-san-francisco-for-170m-2012-03-05|website = MarketWatch|accessdate = 2015-12-21}}</ref>
⚫
==Acquisitions==
⚫
In May 2011, Abcam announced the acquisition of MitoSciences. MitoSciences was a privately held biotech company based in Eugene, Oregon (US). The Company produce and distribute [[immunoassay]] platforms and high performance monoclonal antibodies. It was founded in 2004 with the mission of advancing mitochondrial research and developing products that support critical research in cancer, [[neurodegeneration]], and [[metabolic disorders]].


On 20 January 2015, Abcam announced the acquisition of Firefly BioWorks, a privately held company based in Cambridge, Massachusetts (US),<ref>{{Cite news|title = BRIEF-Abcam to buy Firefly Bioworks for 18.5 mln stg|url = https://www.reuters.com/article/idUSASM0008T020150121|newspaper = Reuters|date = 2015-01-21|access-date = 2015-12-21}}</ref> for {{Currency|18500000|GBP}}.<ref name=":0">{{Cite news|title=Abcam Buys Firefly for $28M to Broaden Multiplex Analysis Capabilities|last=Staff|date=15 February 2015|work=[[Gen. Eng. Biotechnol. News|Genetic Engineering & Biotechnology News]]|issue=4|volume=35|page=6|type=paper}}</ref> Firefly developed a novel [[Multiplex (assay)|multiplex assay]] platform for the detection of [[biomarker]]s, based on a microfabrication technology developed by Daniel Pregibon and Patrick Doyle at [[Massachusetts Institute of Technology]], and launched its first products for the multiplex detection of [[microRNA]] from RNA and crude biofluid.<ref name=":0" /> Firefly was rebranded to FirePlex in 2016.<ref>{{cite web |last1=Dutton |first1=Gail |title=Wisdom of the Antibody Crowd |url=https://www.genengnews.com/magazine/324/wisdom-of-the-antibody-crowd/ |website=GEN |date=30 August 2018 |publisher=Mary Ann Liebert, Inc |accessdate=16 September 2019}}</ref>
On 12 September 2011, Abcam completed the purchase of Ascent Scientific. Ascent Scientific was a company based in Bristol, United Kingdom that provided high-quality biochemical products that modulate the function of proteins for use in life science research.<ref name="Abcam Annual report 2012" />


On 11 November 2015, Abcam announced the acquisition of AxioMx.<ref>{{Cite web|title = Abcam acquires AxioMx to access new growth opportunities and extend antibody leadership|url = http://www.cambridgenetwork.co.uk/news/abcam-acquires-axiomx-to-access-growth/|website = Cambridge Network|accessdate = 2015-12-21}}</ref> AxioMx, based in Branford, Connecticut (US), "provides a comprehensive custom recombinant antibody discovery and development services platform".<ref>{{Cite web|title = Corporate Overview - Axiomxinc.com|url = http://axiomxinc.com/about-us/corporate-overview/|website = Axiomxinc.com|accessdate = 2015-12-21|language = en-US|archive-url = https://web.archive.org/web/20150822022333/http://axiomxinc.com/about-us/corporate-overview/|archive-date = 22 August 2015|url-status = dead}}</ref>
⚫
On 19 April 2012, Abcam completed the purchase of Epitomics. Epitomics was a privately held biotech company in San Francisco, California, focused on the development, production and distribution of rabbit [[monoclonal antibodies]] for biomedical research and diagnostic applications.<ref name="Abcam Annual report 2012" />

Abcam acquired Calico Biolabs in January 2019. A year later, on 6 January 2020, Abcam announces the successful acquisition of Expedeon's Proteomics and Immunology business, which includes Innova and TGR Biosciences.<ref>{{cite web |title=Abcam acquires Calico Biolabs |url=https://www.manufacturingchemist.com/news/article_page/Abcam_acquires_Calico_Biolabs/151262 |website=Manufacturing Chemist |publisher=HPCi Media |accessdate=16 September 2019}}</ref><ref>{{cite web |title=Abcam announces successful acquisition of Expedeon's Proteomics and Immunology business, enhancing its conjugation capability |url=https://www.prnewswire.com/news-releases/abcam-announces-successful-acquisition-of-expedeons-proteomics-and-immunology-business-enhancing-its-conjugation-capability-300981077.html}}</ref> On 4 March 2020, Abcam extend their assay and labelling capabilities by acquiring Marker Gene Technologies for an undisclosed amount. The acquisition of Marker Gene Technologies bring expertise in the areas of biology, organic synthesis and fluorescence chemistry. The team from MGT are experienced in the creation of detection tools that enable enhanced understanding of biological processes.<ref>{{Cite web|title=Abcam Acquires Marker Gene Technologies|url=https://www.genomeweb.com/business-news/abcam-acquires-marker-gene-technologies|access-date=2020-10-06|website=GenomeWeb|date=4 March 2020 |language=en-us}}</ref>


==References==
==References==
Line 45: Line 59:


==External links==
==External links==
*[http://www.abcam.com Abcam website]
*{{official website|https://www.abcamplc.com}}

*[http://www.cambridgenetwork.co.uk/directory/orgprofile/default.aspx?objid=4620 [[Cambridge Network]] profile]
{{Authority control}}


[[Category:Biotechnology companies of the United Kingdom]]
[[Category:Biotechnology companies of the United Kingdom]]
[[Category:Companies based in Cambridge]]
[[Category:Companies based in Cambridge]]
[[Category:Companies listed on the London Stock Exchange]]
[[Category:Companies formerly listed on the Alternative Investment Market]]
[[Category:Companies established in 1998]]
[[Category:Biotechnology companies established in 1998]]
[[Category:1998 establishments in England]]
[[Category:1998 establishments in England]]
[[Category:2023 mergers and acquisitions]]
[[Category:Companies formerly listed on the Nasdaq]]
[[Category:Danaher subsidiaries]]

Latest revision as of 15:06, 2 August 2024

Abcam Limited
Formerly
  • Abcam Limited (1998–2005)
  • Abcam plc (2005–2023)[1]
Company typeSubsidiary
Industry
Founded1998; 26 years ago (1998)
Founders
HeadquartersCambridge Biomedical Campus,
Cambridge
,
UK
Key people
Markus Lusser (president)
Products
RevenueIncrease £361.7 million (2022)[2]
Decrease £(10.1) million (2022)[2]
Decrease £(8.5) million (2022)[2]
Total assetsIncrease £1,057 million (2022)[2]
Total equityIncrease £726.9 million (2022)[2]
Number of employees
1,760 (2022)[2]
Parent
Website

Abcam Limited[1] is a producer, distributor and seller of protein research tools operating worldwide from 13 locations with 1,800 employees of which 400 work in Research and Development (R&D). Abcam was listed on the Nasdaq[3] and the London Stock Exchange until it was acquired by Danaher Corporation in 2023.[4]

History

[edit]

The company was founded in 1998 by Jonathan Milner with co-founders professor Tony Kouzarides and David Cleevely, with the idea of making it easier for research scientists to buy antibodies across the web.[5] Milner was a postdoctoral researcher studying the newly discovered breast cancer protein BRCA2 in Kouzarides' Cambridge University laboratory. The project had slowed because of problems finding quality antibody reagents that had honest and up-to-date information about their uses and limitations. This scenario provided the motivation to form an on-line service that would help themselves and researchers across the globe.[6]

Since its inception in 1998, the company has diversified from carrying only antibodies. It supplies antibody related products such as immunoassays (e.g. SimpleStep ELISA Kits), peptides, proteins and protein detection products (e.g. immunohistochemistry (IHC) staining kits). Abcam also has a portfolio of non-antibody related products such as biochemicals, cellular assays, and epigenetics kits (e.g. FirePlex Multiplex miRNA Kits).

On 28 August 2023, Danaher Corporation announced that it had entered into a definitive agreement to acquire Abcam for approximately $5.7 billion at $24 per share in cash.[7][8][9] The acquisition was completed on December 6.[10]

Acquisitions

[edit]

In May 2011, Abcam announced the acquisition of MitoSciences, a privately held biotech company based in Eugene, Oregon (US).[11] The company produced and distributed immunoassay platforms and high performance monoclonal antibodies. It was founded in 2004 with the mission of advancing mitochondrial research and developing products that support critical research in cancer, neurodegeneration, and metabolic disorders.

On 12 September 2011, Abcam completed the purchase of Ascent Scientific. Ascent Scientific was a company based in Bristol, United Kingdom that provided high-quality biochemical products that modulate the function of proteins for use in life science research. After outsourcing biochemical production, the Bristol site and manufacturing facilities were closed in 2017.[12]

On 19 April 2012, Abcam completed the purchase of Epitomics. Epitomics was a privately held biotech company in Burlingame, California (US) and Hangzhou (China) that focused on the development, production, and distribution of rabbit monoclonal antibodies for biomedical research and diagnostic applications.[13]

On 20 January 2015, Abcam announced the acquisition of Firefly BioWorks, a privately held company based in Cambridge, Massachusetts (US),[14] for £18,500,000.[15] Firefly developed a novel multiplex assay platform for the detection of biomarkers, based on a microfabrication technology developed by Daniel Pregibon and Patrick Doyle at Massachusetts Institute of Technology, and launched its first products for the multiplex detection of microRNA from RNA and crude biofluid.[15] Firefly was rebranded to FirePlex in 2016.[16]

On 11 November 2015, Abcam announced the acquisition of AxioMx.[17] AxioMx, based in Branford, Connecticut (US), "provides a comprehensive custom recombinant antibody discovery and development services platform".[18]

Abcam acquired Calico Biolabs in January 2019. A year later, on 6 January 2020, Abcam announces the successful acquisition of Expedeon's Proteomics and Immunology business, which includes Innova and TGR Biosciences.[19][20] On 4 March 2020, Abcam extend their assay and labelling capabilities by acquiring Marker Gene Technologies for an undisclosed amount. The acquisition of Marker Gene Technologies bring expertise in the areas of biology, organic synthesis and fluorescence chemistry. The team from MGT are experienced in the creation of detection tools that enable enhanced understanding of biological processes.[21]

References

[edit]
  1. ^ a b "Abcam Limited overview - Find and update company information - GOV.UK". Companies House. 12 February 1998. Retrieved 13 February 2024.
  2. ^ a b c d e f "Abcam 2022 Annual Report (Form 20-F)". US Securities and Exchange Commission. 20 March 2023. Retrieved 12 August 2023.
  3. ^ "ABCAM share price (ABCM) - Nasdaq".
  4. ^ "Danaher Completes $5.7B Acquisition of Abcam". Contract Pharma. 6 December 2023.
  5. ^ "Abcam - the next giant of the Life Sciences?". Business Insider. Retrieved 16 June 2016.
  6. ^ "Abcam plc investor relations - Abcam story". www.abcamplc.com. Archived from the original on 8 June 2016. Retrieved 16 June 2016.
  7. ^ Mishra, Manas (28 August 2023). "Danaher to buy Abcam in deal valued at $5.7 billion". Nasdaq. Retrieved 28 August 2023.
  8. ^ "Danaher to Acquire Abcam". Life Sciences Europe. 28 August 2023. Retrieved 27 September 2023.
  9. ^ "Danaher to Acquire Abcam - Aug 28, 2023". www.danaher.com. 28 August 2023. Retrieved 28 August 2023.
  10. ^ "Danaher Completes Acquisition of Abcam". PR Newswire. Retrieved 12 December 2023.
  11. ^ "Abcam Completes $6M Takeover of Mitochondrial Research Tools Specialist MitoSciences". Genetic Engineering & Biology News. 24 May 2011. Retrieved 21 December 2015.
  12. ^ "Abcam H1 2018 Interim Report" (PDF). www.abcamplc.com. Archived from the original (PDF) on 10 May 2018. Retrieved 9 May 2018.
  13. ^ "Abcam to buy Epitomics of San Francisco for $170M". MarketWatch. Retrieved 21 December 2015.
  14. ^ "BRIEF-Abcam to buy Firefly Bioworks for 18.5 mln stg". Reuters. 21 January 2015. Retrieved 21 December 2015.
  15. ^ a b Staff (15 February 2015). "Abcam Buys Firefly for $28M to Broaden Multiplex Analysis Capabilities". Genetic Engineering & Biotechnology News (paper). Vol. 35, no. 4. p. 6.
  16. ^ Dutton, Gail (30 August 2018). "Wisdom of the Antibody Crowd". GEN. Mary Ann Liebert, Inc. Retrieved 16 September 2019.
  17. ^ "Abcam acquires AxioMx to access new growth opportunities and extend antibody leadership". Cambridge Network. Retrieved 21 December 2015.
  18. ^ "Corporate Overview - Axiomxinc.com". Axiomxinc.com. Archived from the original on 22 August 2015. Retrieved 21 December 2015.
  19. ^ "Abcam acquires Calico Biolabs". Manufacturing Chemist. HPCi Media. Retrieved 16 September 2019.
  20. ^ "Abcam announces successful acquisition of Expedeon's Proteomics and Immunology business, enhancing its conjugation capability".
  21. ^ "Abcam Acquires Marker Gene Technologies". GenomeWeb. 4 March 2020. Retrieved 6 October 2020.
[edit]
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