(+)-Larreatricin hydroxylase: Difference between revisions
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{{Short description|Class of enzymes}} |
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{{Infobox enzyme |
{{Infobox enzyme |
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| Name = (+)-Larreatricin hydroxylase |
| Name = (+)-Larreatricin hydroxylase |
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| EC_number = 1.14.99.47 |
| EC_number = 1.14.99.47 |
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| IUBMB_EC_number = 1/14/99/47 |
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'''(+)-Larreatricin hydroxylase''' ({{EC number|1.14.99.47}}) is an [[enzyme]] with |
'''(+)-Larreatricin hydroxylase''' ({{EC number|1.14.99.47}}) is an [[enzyme]] with [[List of enzymes|systematic name]] ''(+)-larreatricin:oxygen 3'-hydroxylase''.<ref>{{cite journal | vauthors = Cho MH, Moinuddin SG, Helms GL, Hishiyama S, Eichinger D, Davin LB, Lewis NG | title = (+)-Larreatricin hydroxylase, an enantio-specific polyphenol oxidase from the creosote bush (Larrea tridentata) | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 100 | issue = 19 | pages = 10641–6 | date = September 2003 | pmid = 12960376 | pmc = 196857 | doi = 10.1073/pnas.1934562100 | bibcode = 2003PNAS..10010641C | doi-access = free }}</ref> This enzyme [[catalysis|catalyses]] the following [[chemical reaction]] |
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: (+)-larreatricin + O<sub>2</sub> + AH<sub>2</sub> <math>\rightleftharpoons</math> (+)-3'-hydroxylarreatricin + A + H<sub>2</sub>O |
: (+)-larreatricin + O<sub>2</sub> + AH<sub>2</sub> <math>\rightleftharpoons</math> (+)-3'-hydroxylarreatricin + A + H<sub>2</sub>O |
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This enzyme is isolated from the plant ''[[Larrea tridentata]]'' (creosote bush) and can be produced recombinantly.<ref>{{cite journal | vauthors = Martin HJ, Kampatsikas I, Oost R, Pretzler M, Al-Sayed E, Roller A, Giester G, Rompel A, Maulide N | display-authors = 6 | title = Total Synthesis, Stereochemical Assignment, and Divergent Enantioselective Enzymatic Recognition of Larreatricin | journal = Chemistry: A European Journal | volume = 24 | issue = 59 | pages = 15756–15760 | date = October 2018 | pmid = 30113748 | pmc = 6220842 | doi = 10.1002/chem.201803785 }}</ref> |
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This enzyme is isolated from the plant ''[[Larrea tridentata]]'' (creosote bush). |
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== References == |
== References == |
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{{Dioxygenases}} |
{{Dioxygenases}} |
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{{Enzymes}} |
{{Enzymes}} |
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[[Category:EC 1.14.99]] |
[[Category:EC 1.14.99]] |
Latest revision as of 12:15, 26 August 2023
(+)-Larreatricin hydroxylase | |||||||||
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Identifiers | |||||||||
EC no. | 1.14.99.47 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
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(+)-Larreatricin hydroxylase (EC 1.14.99.47) is an enzyme with systematic name (+)-larreatricin:oxygen 3'-hydroxylase.[1] This enzyme catalyses the following chemical reaction
- (+)-larreatricin + O2 + AH2 (+)-3'-hydroxylarreatricin + A + H2O
This enzyme is isolated from the plant Larrea tridentata (creosote bush) and can be produced recombinantly.[2]
References
[edit]- ^ Cho MH, Moinuddin SG, Helms GL, Hishiyama S, Eichinger D, Davin LB, Lewis NG (September 2003). "(+)-Larreatricin hydroxylase, an enantio-specific polyphenol oxidase from the creosote bush (Larrea tridentata)". Proceedings of the National Academy of Sciences of the United States of America. 100 (19): 10641–6. Bibcode:2003PNAS..10010641C. doi:10.1073/pnas.1934562100. PMC 196857. PMID 12960376.
- ^ Martin HJ, Kampatsikas I, Oost R, Pretzler M, Al-Sayed E, Roller A, et al. (October 2018). "Total Synthesis, Stereochemical Assignment, and Divergent Enantioselective Enzymatic Recognition of Larreatricin". Chemistry: A European Journal. 24 (59): 15756–15760. doi:10.1002/chem.201803785. PMC 6220842. PMID 30113748.
External links
[edit]- (+)-larreatricin+hydroxylase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)