BRD8: Difference between revisions

BRD8
Identifiers
Aliases	BRD8, SMAP, SMAP2, p120, bromodomain containing 8
External IDs	OMIM: 602848; MGI: 1925906; HomoloGene: 41790; GeneCards: BRD8; OMA:BRD8 - orthologs
Gene location (Human)
Chr.	Chromosome 5 (human)
End	138,178,953 bp
Gene location (Mouse)
Chr.	Chromosome 18 (mouse)
End	34,757,654 bp
RNA expression pattern
	Top expressed in
	right testis; ; left testis; ; ventricular zone; ; Pituitary Gland; ; anterior pituitary; ; right lobe of thyroid gland; ; right uterine tube; ; left lobe of thyroid gland; ; middle temporal gyrus; ; buccal mucosa cell;
	Top expressed in
	neural layer of retina; ; Rostral migratory stream; ; ventricular zone; ; tail of embryo; ; genital tubercle; ; spermatocyte; ; blastocyst; ; ganglionic eminence; ; primitive streak; ; yolk sac;
	More reference expression data
	; ;
	More reference expression data
Gene ontology
Molecular function	DNA-binding transcription factor activity; protein binding; nuclear receptor activity;
Cellular component	mitochondrion; nucleus; nucleoplasm; Swr1 complex; NuA4 histone acetyltransferase complex;
Biological process	regulation of transcription by RNA polymerase II; histone H2A acetylation; regulation of growth; cell surface receptor signaling pathway; regulation of transcription, DNA-templated; transcription, DNA-templated; signal transduction; histone H4 acetylation; positive regulation of transcription by RNA polymerase II; intracellular receptor signaling pathway; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	10902
	78656
	ENSG00000112983
	ENSMUSG00000003778
	Q9H0E9
	Q8R3B7
NM_001164326; NM_001300961; NM_001300962; NM_001300966; NM_006696;
	NM_139199; NM_183359
	NM_001289606; NM_001289607; NM_030147; NM_001361136
NP_001157798; NP_001287890; NP_001287891; NP_001287895; NP_006687;
	NP_631938
	NP_001276535; NP_001276536; NP_084423; NP_001348065
	Wikidata
View/Edit Human	View/Edit Mouse

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Latest revision as of 02:49, 29 January 2023

Bromodomain-containing protein 8 is a protein that in humans is encoded by the BRD8 gene.^[5]^[6]^[7]

The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.^[7]

Interactions

BRD8 has been shown to interact with Thyroid hormone receptor beta^[6] and Retinoid X receptor alpha.^[8]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000112983 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000003778 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nielsen MS, Petersen CM, Gliemann J, Madsen P (April 1996). "Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1306 (1): 14–6. doi:10.1016/0167-4781(95)00239-1. PMID 8611617.
^ ^a ^b Monden T, Wondisford FE, Hollenberg AN (November 1997). "Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein". The Journal of Biological Chemistry. 272 (47): 29834–41. doi:10.1074/jbc.272.47.29834. PMID 9368056.
^ ^a ^b "Entrez Gene: BRD8 bromodomain containing 8".
^ Monden T, Kishi M, Hosoya T, Satoh T, Wondisford FE, Hollenberg AN, Yamada M, Mori M (October 1999). "p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers". Molecular Endocrinology. 13 (10): 1695–703. doi:10.1210/mend.13.10.0353. PMID 10517671. S2CID 25098867.

External links

Human BRD8 genome location and BRD8 gene details page in the UCSC Genome Browser.
Human SMAP2 genome location and SMAP2 gene details page in the UCSC Genome Browser.

Doyon Y, Côté J (April 2004). "The highly conserved and multifunctional NuA4 HAT complex". Current Opinion in Genetics & Development. 14 (2): 147–54. doi:10.1016/j.gde.2004.02.009. PMID 15196461.
Maruyama K, Sugano S (January 1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Monden T, Kishi M, Hosoya T, Satoh T, Wondisford FE, Hollenberg AN, Yamada M, Mori M (October 1999). "p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers". Molecular Endocrinology. 13 (10): 1695–703. doi:10.1210/mend.13.10.0353. PMID 10517671. S2CID 25098867.
Lai F, Godley LA, Joslin J, Fernald AA, Liu J, Espinosa R, Zhao N, Pamintuan L, Till BG, Larson RA, Qian Z, Le Beau MM (January 2001). "Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q)". Genomics. 71 (2): 235–45. doi:10.1006/geno.2000.6414. PMID 11161817.
Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A (March 2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Research. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
Cai Y, Jin J, Tomomori-Sato C, Sato S, Sorokina I, Parmely TJ, Conaway RC, Conaway JW (October 2003). "Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex". The Journal of Biological Chemistry. 278 (44): 42733–6. doi:10.1074/jbc.C300389200. PMID 12963728.
Doyon Y, Selleck W, Lane WS, Tan S, Côté J (March 2004). "Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans". Molecular and Cellular Biology. 24 (5): 1884–96. doi:10.1128/MCB.24.5.1884-1896.2004. PMC 350560. PMID 14966270.
Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP (August 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Cai Y, Jin J, Florens L, Swanson SK, Kusch T, Li B, Workman JL, Washburn MP, Conaway RC, Conaway JW (April 2005). "The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes". The Journal of Biological Chemistry. 280 (14): 13665–70. doi:10.1074/jbc.M500001200. PMID 15647280.
Benevolenskaya EV, Murray HL, Branton P, Young RA, Kaelin WG (June 2005). "Binding of pRB to the PHD protein RBP2 promotes cellular differentiation". Molecular Cell. 18 (6): 623–35. doi:10.1016/j.molcel.2005.05.012. PMID 15949438.
Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Natsume W, Tanabe K, Kon S, Yoshida N, Watanabe T, Torii T, Satake M (June 2006). "SMAP2, a novel ARF GTPase-activating protein, interacts with clathrin and clathrin assembly protein and functions on the AP-1-positive early endosome/trans-Golgi network". Molecular Biology of the Cell. 17 (6): 2592–603. doi:10.1091/mbc.E05-10-0909. PMC 1475504. PMID 16571680.
Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP (October 2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nature Biotechnology. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (November 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article on a gene on human chromosome 5 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000112983 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000003778 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8611617-5] Nielsen MS, Petersen CM, Gliemann J, Madsen P (April 1996). "Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1306 (1): 14–6. doi:10.1016/0167-4781(95)00239-1. PMID 8611617.

[pmid9368056-6] Monden T, Wondisford FE, Hollenberg AN (November 1997). "Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein". The Journal of Biological Chemistry. 272 (47): 29834–41. doi:10.1074/jbc.272.47.29834. PMID 9368056.

[entrez-7] "Entrez Gene: BRD8 bromodomain containing 8".

[pmid10517671-8] Monden T, Kishi M, Hosoya T, Satoh T, Wondisford FE, Hollenberg AN, Yamada M, Mori M (October 1999). "p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers". Molecular Endocrinology. 13 (10): 1695–703. doi:10.1210/mend.13.10.0353. PMID 10517671. S2CID 25098867.

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@@ Line 1: / Line 1: @@
+{{Short description|Protein-coding gene in the species Homo sapiens}}
 {{Infobox_gene}}
-'''Bromodomain-containing protein 8''' is a [[protein]] that in humans is encoded by the ''BRD8'' [[gene]].<ref name="pmid8611617">{{cite journal | vauthors = Nielsen MS, Petersen CM, Gliemann J, Madsen P | title = Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain | journal = Biochim Biophys Acta | volume = 1306 | issue = 1 | pages = 14–6 |date=Jun 1996 | pmid = 8611617 | pmc =  | doi =  10.1016/0167-4781(95)00239-1}}</ref><ref name="pmid9368056">{{cite journal | vauthors = Monden T, Wondisford FE, Hollenberg AN | title = Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein | journal = J Biol Chem | volume = 272 | issue = 47 | pages = 29834–41 |date=Dec 1997 | pmid = 9368056 | pmc =  | doi =10.1074/jbc.272.47.29834  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: BRD8 bromodomain containing 8| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10902| accessdate = }}</ref>
+'''Bromodomain-containing protein 8''' is a [[protein]] that in humans is encoded by the ''BRD8'' [[gene]].<ref name="pmid8611617">{{cite journal | vauthors = Nielsen MS, Petersen CM, Gliemann J, Madsen P | title = Cloning and sequencing of a human cDNA encoding a putative transcription factor containing a bromodomain | journal = Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression | volume = 1306 | issue = 1 | pages = 14–6 | date = April 1996 | pmid = 8611617 | doi = 10.1016/0167-4781(95)00239-1 }}</ref><ref name="pmid9368056">{{cite journal | vauthors = Monden T, Wondisford FE, Hollenberg AN | title = Isolation and characterization of a novel ligand-dependent thyroid hormone receptor-coactivating protein | journal = The Journal of Biological Chemistry | volume = 272 | issue = 47 | pages = 29834–41 | date = November 1997 | pmid = 9368056 | doi = 10.1074/jbc.272.47.29834 | doi-access = free }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: BRD8 bromodomain containing 8| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10902}}</ref>
+The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.<ref name="entrez" />
-<!-- The PBB_Summary template is automatically maintained by Protein Box Bot.  See Template:PBB_Controls to Stop updates. -->
-{{PBB_Summary
-| section_title =
-| summary_text = The protein encoded by this gene interacts with thyroid hormone receptor in a ligand-dependent manner and enhances thyroid hormone-dependent activation from thyroid response elements. This protein contains a bromodomain and is thought to be a nuclear receptor coactivator. Three alternatively spliced transcript variants that encode distinct isoforms have been identified.<ref name="entrez" />
-}}
-==Interactions==
+== Interactions ==
-BRD8 has been shown to [[Protein-protein interaction|interact]] with [[Thyroid hormone receptor beta]]<ref name=pmid9368056 /> and [[Retinoid X receptor alpha]].<ref name=pmid10517671>{{cite journal |last=Monden |first=T |author2=Kishi M |author3=Hosoya T |author4=Satoh T |author5=Wondisford F E |author6=Hollenberg A N |author7=Yamada M |author8=Mori M  |date=Oct 1999 |title=p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers |journal=Mol. Endocrinol. |volume=13 |issue=10 |pages=1695–703 |publisher= |location = UNITED STATES| issn = 0888-8809| pmid = 10517671 | bibcode = | oclc =| id = | url = | language = | format = | accessdate = | laysummary = | laysource = | laydate = | quote = |doi=10.1210/me.13.10.1695 }}</ref>
+BRD8 has been shown to [[Protein-protein interaction|interact]] with [[Thyroid hormone receptor beta]]<ref name=pmid9368056 /> and [[Retinoid X receptor alpha]].<ref name=pmid10517671>{{cite journal | vauthors = Monden T, Kishi M, Hosoya T, Satoh T, Wondisford FE, Hollenberg AN, Yamada M, Mori M | title = p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers | journal = Molecular Endocrinology | volume = 13 | issue = 10 | pages = 1695–703 | date = October 1999 | doi = 10.1210/mend.13.10.0353 | pmid = 10517671 | s2cid = 25098867 | doi-access = free }}</ref>
-==References==
+== References ==
 {{reflist}}
+== External links ==
-==Further reading==
+* {{UCSC gene info|BRD8}}
+* {{UCSC gene info|SMAP2}}
+== Further reading ==
 {{refbegin | 2}}
+* {{cite journal | vauthors = Doyon Y, Côté J | title = The highly conserved and multifunctional NuA4 HAT complex | journal = Current Opinion in Genetics & Development | volume = 14 | issue = 2 | pages = 147–54 | date = April 2004 | pmid = 15196461 | doi = 10.1016/j.gde.2004.02.009 }}
-{{PBB_Further_reading
+* {{cite journal | vauthors = Maruyama K, Sugano S | title = Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides | journal = Gene | volume = 138 | issue = 1–2 | pages = 171–4 | date = January 1994 | pmid = 8125298 | doi = 10.1016/0378-1119(94)90802-8 }}
-| citations =
-*{{cite journal  | vauthors=Doyon Y, Côté J |title=The highly conserved and multifunctional NuA4 HAT complex |journal=Curr. Opin. Genet. Dev. |volume=14 |issue= 2 |pages= 147–54 |year= 2004 |pmid= 15196461 |doi= 10.1016/j.gde.2004.02.009 }}
+* {{cite journal | vauthors = Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S | title = Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library | journal = Gene | volume = 200 | issue = 1–2 | pages = 149–56 | date = October 1997 | pmid = 9373149 | doi = 10.1016/S0378-1119(97)00411-3 }}
-*{{cite journal  | vauthors=Maruyama K, Sugano S |title=Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides |journal=Gene |volume=138 |issue= 1–2 |pages= 171–4 |year= 1994 |pmid= 8125298 |doi=10.1016/0378-1119(94)90802-8  }}
+* {{cite journal | vauthors = Monden T, Kishi M, Hosoya T, Satoh T, Wondisford FE, Hollenberg AN, Yamada M, Mori M | title = p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers | journal = Molecular Endocrinology | volume = 13 | issue = 10 | pages = 1695–703 | date = October 1999 | doi = 10.1210/mend.13.10.0353 | pmid = 10517671 | s2cid = 25098867 | doi-access = free }}
-*{{cite journal  | vauthors=Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K |title=Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library |journal=Gene |volume=200 |issue= 1–2 |pages= 149–56 |year= 1997 |pmid= 9373149 |doi=10.1016/S0378-1119(97)00411-3  |display-authors=etal}}
+* {{cite journal | vauthors = Lai F, Godley LA, Joslin J, Fernald AA, Liu J, Espinosa R, Zhao N, Pamintuan L, Till BG, Larson RA, Qian Z, Le Beau MM | title = Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q) | journal = Genomics | volume = 71 | issue = 2 | pages = 235–45 | date = January 2001 | pmid = 11161817 | doi = 10.1006/geno.2000.6414 }}
+* {{cite journal | vauthors = Wiemann S, Weil B, Wellenreuther R, Gassenhuber J, Glassl S, Ansorge W, Böcher M, Blöcker H, Bauersachs S, Blum H, Lauber J, Düsterhöft A, Beyer A, Köhrer K, Strack N, Mewes HW, Ottenwälder B, Obermaier B, Tampe J, Heubner D, Wambutt R, Korn B, Klein M, Poustka A | title = Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs | journal = Genome Research | volume = 11 | issue = 3 | pages = 422–35 | date = March 2001 | pmid = 11230166 | pmc = 311072 | doi = 10.1101/gr.GR1547R }}
-*{{cite journal  | vauthors=Monden T, Kishi M, Hosoya T |title=p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers |journal=Mol. Endocrinol. |volume=13 |issue= 10 |pages= 1695–703 |year= 1999 |pmid= 10517671 |doi=10.1210/me.13.10.1695  |display-authors=etal}}
-*{{cite journal  | vauthors=Lai F, Godley LA, Joslin J |title=Transcript map and comparative analysis of the 1.5-Mb commonly deleted segment of human 5q31 in malignant myeloid diseases with a del(5q) |journal=Genomics |volume=71 |issue= 2 |pages= 235–45 |year= 2001 |pmid= 11161817 |doi= 10.1006/geno.2000.6414 |display-authors=etal}}
+* {{cite journal | vauthors = Cai Y, Jin J, Tomomori-Sato C, Sato S, Sorokina I, Parmely TJ, Conaway RC, Conaway JW | title = Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex | journal = The Journal of Biological Chemistry | volume = 278 | issue = 44 | pages = 42733–6 | date = October 2003 | pmid = 12963728 | doi = 10.1074/jbc.C300389200 | doi-access = free }}
-*{{cite journal  | vauthors=Wiemann S, Weil B, Wellenreuther R |title=Toward a Catalog of Human Genes and Proteins: Sequencing and Analysis of 500 Novel Complete Protein Coding Human cDNAs |journal=Genome Res. |volume=11 |issue= 3 |pages= 422–35 |year= 2001 |pmid= 11230166 |doi= 10.1101/gr.GR1547R  | pmc=311072 |display-authors=etal}}
+* {{cite journal | vauthors = Doyon Y, Selleck W, Lane WS, Tan S, Côté J | title = Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans | journal = Molecular and Cellular Biology | volume = 24 | issue = 5 | pages = 1884–96 | date = March 2004 | pmid = 14966270 | pmc = 350560 | doi = 10.1128/MCB.24.5.1884-1896.2004 }}
-*{{cite journal  | vauthors=Strausberg RL, Feingold EA, Grouse LH |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899–903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899  | pmc=139241 |display-authors=etal}}
+* {{cite journal | vauthors = Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, Cohn MA, Cantley LC, Gygi SP | title = Large-scale characterization of HeLa cell nuclear phosphoproteins | journal = Proceedings of the National Academy of Sciences of the United States of America | volume = 101 | issue = 33 | pages = 12130–5 | date = August 2004 | pmid = 15302935 | pmc = 514446 | doi = 10.1073/pnas.0404720101 | bibcode = 2004PNAS..10112130B | doi-access = free }}
-*{{cite journal  | vauthors=Cai Y, Jin J, Tomomori-Sato C |title=Identification of new subunits of the multiprotein mammalian TRRAP/TIP60-containing histone acetyltransferase complex |journal=J. Biol. Chem. |volume=278 |issue= 44 |pages= 42733–6 |year= 2003 |pmid= 12963728 |doi= 10.1074/jbc.C300389200 |display-authors=etal}}
+* {{cite journal | vauthors = Cai Y, Jin J, Florens L, Swanson SK, Kusch T, Li B, Workman JL, Washburn MP, Conaway RC, Conaway JW | title = The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes | journal = The Journal of Biological Chemistry | volume = 280 | issue = 14 | pages = 13665–70 | date = April 2005 | pmid = 15647280 | doi = 10.1074/jbc.M500001200 | doi-access = free }}
-*{{cite journal  | vauthors=Doyon Y, Selleck W, Lane WS |title=Structural and Functional Conservation of the NuA4 Histone Acetyltransferase Complex from Yeast to Humans |journal=Mol. Cell. Biol. |volume=24 |issue= 5 |pages= 1884–96 |year= 2004 |pmid= 14966270 |doi=10.1128/MCB.24.5.1884-1896.2004  | pmc=350560  |display-authors=etal}}
+* {{cite journal | vauthors = Benevolenskaya EV, Murray HL, Branton P, Young RA, Kaelin WG | title = Binding of pRB to the PHD protein RBP2 promotes cellular differentiation | journal = Molecular Cell | volume = 18 | issue = 6 | pages = 623–35 | date = June 2005 | pmid = 15949438 | doi = 10.1016/j.molcel.2005.05.012 | doi-access = free }}
+* {{cite journal | vauthors = Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M | title = Towards a proteome-scale map of the human protein-protein interaction network | journal = Nature | volume = 437 | issue = 7062 | pages = 1173–8 | date = October 2005 | pmid = 16189514 | doi = 10.1038/nature04209 | bibcode = 2005Natur.437.1173R | s2cid = 4427026 }}
-*{{cite journal  | vauthors=Beausoleil SA, Jedrychowski M, Schwartz D |title=Large-scale characterization of HeLa cell nuclear phosphoproteins |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=101 |issue= 33 |pages= 12130–5 |year= 2004 |pmid= 15302935 |doi= 10.1073/pnas.0404720101  | pmc=514446 |display-authors=etal}}
-*{{cite journal  | vauthors=Gerhard DS, Wagner L, Feingold EA |title=The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC) |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121–7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504  | pmc=528928 |display-authors=etal}}
+* {{cite journal | vauthors = Natsume W, Tanabe K, Kon S, Yoshida N, Watanabe T, Torii T, Satake M | title = SMAP2, a novel ARF GTPase-activating protein, interacts with clathrin and clathrin assembly protein and functions on the AP-1-positive early endosome/trans-Golgi network | journal = Molecular Biology of the Cell | volume = 17 | issue = 6 | pages = 2592–603 | date = June 2006 | pmid = 16571680 | pmc = 1475504 | doi = 10.1091/mbc.E05-10-0909 }}
-*{{cite journal  | vauthors=Cai Y, Jin J, Florens L |title=The mammalian YL1 protein is a shared subunit of the TRRAP/TIP60 histone acetyltransferase and SRCAP complexes |journal=J. Biol. Chem. |volume=280 |issue= 14 |pages= 13665–70 |year= 2005 |pmid= 15647280 |doi= 10.1074/jbc.M500001200 |display-authors=etal}}
+* {{cite journal | vauthors = Beausoleil SA, Villén J, Gerber SA, Rush J, Gygi SP | title = A probability-based approach for high-throughput protein phosphorylation analysis and site localization | journal = Nature Biotechnology | volume = 24 | issue = 10 | pages = 1285–92 | date = October 2006 | pmid = 16964243 | doi = 10.1038/nbt1240 | s2cid = 14294292 }}
-*{{cite journal  | vauthors=Benevolenskaya EV, Murray HL, Branton P |title=Binding of pRB to the PHD protein RBP2 promotes cellular differentiation |journal=Mol. Cell |volume=18 |issue= 6 |pages= 623–35 |year= 2005 |pmid= 15949438 |doi= 10.1016/j.molcel.2005.05.012 |display-authors=etal}}
+* {{cite journal | vauthors = Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M | title = Global, in vivo, and site-specific phosphorylation dynamics in signaling networks | journal = Cell | volume = 127 | issue = 3 | pages = 635–48 | date = November 2006 | pmid = 17081983 | doi = 10.1016/j.cell.2006.09.026 | s2cid = 7827573 | doi-access = free }}
-*{{cite journal  | vauthors=Rual JF, Venkatesan K, Hao T |title=Towards a proteome-scale map of the human protein-protein interaction network |journal=Nature |volume=437 |issue= 7062 |pages= 1173–8 |year= 2005 |pmid= 16189514 |doi= 10.1038/nature04209 |display-authors=etal}}
-*{{cite journal  | vauthors=Natsume W, Tanabe K, Kon S |title=SMAP2, a Novel ARF GTPase-activating Protein, Interacts with Clathrin and Clathrin Assembly Protein and Functions on the AP-1–positive Early Endosome/Trans-Golgi Network |journal=Mol. Biol. Cell |volume=17 |issue= 6 |pages= 2592–603 |year= 2006 |pmid= 16571680 |doi= 10.1091/mbc.E05-10-0909  | pmc=1475504 |display-authors=etal}}
-*{{cite journal  | vauthors=Beausoleil SA, Villén J, Gerber SA |title=A probability-based approach for high-throughput protein phosphorylation analysis and site localization |journal=Nat. Biotechnol. |volume=24 |issue= 10 |pages= 1285–92 |year= 2006 |pmid= 16964243 |doi= 10.1038/nbt1240 |display-authors=etal}}
-*{{cite journal  | vauthors=Olsen JV, Blagoev B, Gnad F |title=Global, in vivo, and site-specific phosphorylation dynamics in signaling networks |journal=Cell |volume=127 |issue= 3 |pages= 635–48 |year= 2006 |pmid= 17081983 |doi= 10.1016/j.cell.2006.09.026 |display-authors=etal}}
-}}
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