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{{Short description|German physician}}
[[File:Josef von Mering 2.jpg|Josef von Mering|thumb]]
[[File:Josef von Mering 2.jpg|Josef von Mering|thumb]]
'''Josef, Baron von Mering''' (28 February 1849, in [[Cologne]] – 5 January 1908, at [[Halle an der Saale]], [[Germany]]) was a German physician.
'''Josef, Baron von Mering''' (28 February 1849, in [[Cologne]] – 5 January 1908, at [[Halle an der Saale]], [[Germany]]) was a German physician.
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Mering was curious about the [[pancreas]], a [[comma]] shaped organ, situated between the [[stomach]] and the [[small intestine]]. In an effort to discover its function, he removed the organ from a dog. The dog was then noticed frequently urinating on the floor, although it was house trained. Mering realised that this was a symptom of [[diabetes]] and tested the [[urine]], which was found to be high in sugar, confirming his suspicion.
Mering was curious about the [[pancreas]], a [[comma]] shaped organ, situated between the [[stomach]] and the [[small intestine]]. In an effort to discover its function, he removed the organ from a dog. The dog was then noticed frequently urinating on the floor, although it was house trained. Mering realised that this was a symptom of [[diabetes]] and tested the [[urine]], which was found to be high in sugar, confirming his suspicion.


Josef von Mering helped to discover [[barbiturates]], a class of sedative drugs used for insomnia, epilepsy, anxiety, and anesthesia. In 1903, he published observations that [[barbital]] (then known as diethyl-barbituric acid) has sedative properties in humans. In 1904, he helped to launch barbital under the brand name Veronal. Veronal was the first commercially available barbiturate sedative in any country. Von Mering collaborated with the chemist [[Hermann Emil Fischer|Emil Fischer]], who was also involved in the discovery of barbital.(2)
Josef von Mering helped to discover [[barbiturates]], a class of [[sedative]] drugs used for insomnia, epilepsy, anxiety, and anesthesia. In 1903, he published observations that [[barbital]] (then known as diethyl-barbituric acid) has sedative properties in humans. In 1904, he helped to launch barbital under the brand name Veronal. Veronal was the first commercially available barbiturate sedative in any country. Von Mering collaborated with the chemist [[Hermann Emil Fischer|Emil Fischer]], who was also involved in the discovery of barbital.<ref>{{Cite journal|last=López-Muñoz|first=Francisco|last2=Ucha-Udabe|first2=Ronaldo|last3=Alamo|first3=Cecilio|date=December 2005|title=The history of barbiturates a century after their clinical introduction|journal=Neuropsychiatric Disease and Treatment|volume=1|issue=4|pages=329–343|issn=1176-6328|pmc=2424120|pmid=18568113}}</ref>


==References==
==References==
{{Reflist}}
<references group="" responsive="0"></references>

* [http://www.britannica.com/eb/article-9052136 Joseph von Mering] at [[Encyclopædia Britannica]]
* [http://www.britannica.com/eb/article-9052136 Joseph von Mering] at [[Encyclopædia Britannica]]
* [https://www.ncbi.nlm.nih.gov/pmc/articles/pmc2424120/ The History of Barbiturates (López-Muñoz et al., 2005)]


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[[Category:1908 deaths]]
[[Category:1908 deaths]]
[[Category:19th-century German physicians]]
[[Category:19th-century German physicians]]
[[Category:People from Cologne]]
[[Category:Physicians from Cologne]]
[[Category:People from the Rhine Province]]
[[Category:People from the Rhine Province]]
[[Category:University of Bonn alumni]]
[[Category:University of Bonn alumni]]
[[Category:University of Greifswald alumni]]
[[Category:University of Greifswald alumni]]
[[Category:University of Strasbourg alumni]]
[[Category:University of Strasbourg alumni]]
[[Category:University of Strasbourg faculty]]
[[Category:Academic staff of the University of Strasbourg]]
[[Category:Martin Luther University of Halle-Wittenberg faculty]]
[[Category:Academic staff of the Martin Luther University of Halle-Wittenberg]]





Latest revision as of 12:38, 14 July 2024

Josef von Mering

Josef, Baron von Mering (28 February 1849, in Cologne – 5 January 1908, at Halle an der Saale, Germany) was a German physician.

Working at the University of Strasbourg, Mering was the first person to discover (in conjunction with Oskar Minkowski) that one of the pancreatic functions is the production of insulin, a hormone which controls blood sugar levels.

Mering was curious about the pancreas, a comma shaped organ, situated between the stomach and the small intestine. In an effort to discover its function, he removed the organ from a dog. The dog was then noticed frequently urinating on the floor, although it was house trained. Mering realised that this was a symptom of diabetes and tested the urine, which was found to be high in sugar, confirming his suspicion.

Josef von Mering helped to discover barbiturates, a class of sedative drugs used for insomnia, epilepsy, anxiety, and anesthesia. In 1903, he published observations that barbital (then known as diethyl-barbituric acid) has sedative properties in humans. In 1904, he helped to launch barbital under the brand name Veronal. Veronal was the first commercially available barbiturate sedative in any country. Von Mering collaborated with the chemist Emil Fischer, who was also involved in the discovery of barbital.[1]

References

[edit]
  1. ^ López-Muñoz, Francisco; Ucha-Udabe, Ronaldo; Alamo, Cecilio (December 2005). "The history of barbiturates a century after their clinical introduction". Neuropsychiatric Disease and Treatment. 1 (4): 329–343. ISSN 1176-6328. PMC 2424120. PMID 18568113.