Hypertrophy: Difference between revisions
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Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its component [[Cell (biology)|cells]].<ref name="Muscle Hypertrophy">{{cite web|last1=Hernandez|first1=Richard|last2=Kravitz|first2=Len|title=Skeletal muscle hypertrophy|url=https://www.unm.edu/~lkravitz/Article%20folder/hypertrophy.html|website=www.unm.edu}}</ref> It is distinguished from [[hyperplasia]], in which the cells remain approximately the same size but increase in number.<ref>Updated by Linda J. Vorvick. 8/14/15.[https://medlineplus.gov/ency/article/003441.htm Hyperplasia]</ref> Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the [[hormone|hormonally]]-induced proliferation and enlargement of the cells of the [[uterus]] during [[pregnancy]]. |
'''Hypertrophy''' is the increase in the volume of an organ or tissue due to the enlargement of its component [[Cell (biology)|cells]].<ref name="Muscle Hypertrophy">{{cite web|last1=Hernandez|first1=Richard|last2=Kravitz|first2=Len|title=Skeletal muscle hypertrophy|url=https://www.unm.edu/~lkravitz/Article%20folder/hypertrophy.html|website=www.unm.edu}}</ref> It is distinguished from [[hyperplasia]], in which the cells remain approximately the same size but increase in number.<ref>Updated by Linda J. Vorvick. 8/14/15.[https://medlineplus.gov/ency/article/003441.htm Hyperplasia]</ref> Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the [[hormone|hormonally]]-induced proliferation and enlargement of the cells of the [[uterus]] during [[pregnancy]]. |
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'''Eccentric hypertrophy''' is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the [[left ventricle]] of heart.<ref name=Kusumoto2004 >{{citation | last=Kusumoto | first=F. M. | year=2004 | title=Cardiovascular Pathophysiology | publisher=Hayes Barton Press | isbn=978-1-59377-189-8 | url=https://books.google.com/books?id=FHT_w_gUeK4C&q=Eccentric+hypertrophy&pg=PA22 | pages=20–22 }}</ref> [[Sarcomere]]s are added in series, as for example in [[dilated cardiomyopathy]] (in contrast to [[hypertrophic cardiomyopathy]], a type of [[concentric hypertrophy]], where sarcomeres are added in parallel). |
'''Eccentric hypertrophy''' is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the [[left ventricle]] of heart.<ref name=Kusumoto2004 >{{citation | last=Kusumoto | first=F. M. | year=2004 | title=Cardiovascular Pathophysiology | publisher=Hayes Barton Press | isbn=978-1-59377-189-8 | url=https://books.google.com/books?id=FHT_w_gUeK4C&q=Eccentric+hypertrophy&pg=PA22 | pages=20–22 }}</ref> [[Sarcomere]]s are added in series, as for example in [[dilated cardiomyopathy]] (in contrast to [[hypertrophic cardiomyopathy]], a type of [[concentric hypertrophy]], where sarcomeres are added in parallel). |
Revision as of 08:50, 9 January 2023
This article needs more reliable medical references for verification or relies too heavily on primary sources. (May 2017) |
Hypertrophy | |
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Hypertrophy results from an increase in cell size, whereas hyperplasia stems from an increase in cell number |
Hypertrophy is the increase in the volume of an organ or tissue due to the enlargement of its component cells.[1] It is distinguished from hyperplasia, in which the cells remain approximately the same size but increase in number.[2] Although hypertrophy and hyperplasia are two distinct processes, they frequently occur together, such as in the case of the hormonally-induced proliferation and enlargement of the cells of the uterus during pregnancy.
Eccentric hypertrophy is a type of hypertrophy where the walls and chamber of a hollow organ undergo growth in which the overall size and volume are enlarged. It is applied especially to the left ventricle of heart.[3] Sarcomeres are added in series, as for example in dilated cardiomyopathy (in contrast to hypertrophic cardiomyopathy, a type of concentric hypertrophy, where sarcomeres are added in parallel).
Gallery
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Hypertrophy of breast, c. 1870
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Hypertrophy of the clitoris
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Hypertrophy of the foot, partial
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Forensic post-mortem examination of a case of hypertrophic cardiomyopathy, showing thickening of the cardiac muscle
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Hypertrophy of the ear (macrotia)
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Kidney hypertrophy
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Hypertrophy of the upper lip
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Hypertrophy of the temporal muscles
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See also
- Athlete's heart
- Ventricular hypertrophy (including left ventricular hypertrophy and right ventricular hypertrophy)
- Muscle hypertrophy
- List of biological development disorders
References
- ^ Hernandez, Richard; Kravitz, Len. "Skeletal muscle hypertrophy". www.unm.edu.
- ^ Updated by Linda J. Vorvick. 8/14/15.Hyperplasia
- ^ Kusumoto, F. M. (2004), Cardiovascular Pathophysiology, Hayes Barton Press, pp. 20–22, ISBN 978-1-59377-189-8