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'''Bunamidine''' is an [[anthelmintic]] drug used in veterinary medicine to treat infections by tapeworm parasites of the genus ''[[Taenia (tapeworm)|Taenia]]'';<ref>{{cite web | url = https://go.drugbank.com/drugs/DB11501 | title = Bunamidine | work = [[DrugBank]] }}</ref> thus it is classified as a [[taeniacide]].
'''Bunamidine''' is an [[anthelmintic]] drug used in veterinary medicine to treat infections by tapeworm parasites of the genus ''[[Taenia (tapeworm)|Taenia]]'';<ref>{{cite web | url = https://go.drugbank.com/drugs/DB11501 | title = Bunamidine | work = [[DrugBank]] }}</ref> thus it is classified as a [[taeniacide]].


It is also effective against ''[[Echinococcus granulosus]]'' (dog tapeworm)<ref>{{Cite journal | pmid = 1169897 | date = 1975 | last1 = Andersen | first1 = F. L. | last2 = Loveless | first2 = R. M. | last3 = Jensen | first3 = L. A. | title = Efficacy of bunamidine hydrochloride against immature and mature stages of Echinococcus granulosus | journal = American Journal of Veterinary Research | volume = 36 | issue = 5 | pages = 673–675 }}</ref> and ''[[Hymenolepis diminuta]]'' (rat tapeworm).<ref>{{cite journal | doi = 10.1016/0304-4017(79)90008-6 | title = The effects of bunamidine HCL on Hymenolepis diminuta in vitro | date = 1979 | last1 = Chatfield | first1 = Ronald C. | last2 = Yeary | first2 = Roger A. | journal = Veterinary Parasitology | volume = 5 | issue = 2–3 | pages = 177–193 }}</ref>
It is also effective against ''[[Echinococcus granulosus]]'' (dog tapeworm)<ref>{{cite journal | vauthors = Andersen FL, Loveless RM, Jensen LA | title = Efficacy of bunamidine hydrochloride against immature and mature stages of Echinococcus granulosus | journal = American Journal of Veterinary Research | volume = 36 | issue = 5 | pages = 673–675 | date = May 1975 | pmid = 1169897 }}</ref> and ''[[Hymenolepis diminuta]]'' (rat tapeworm).<ref>{{cite journal | doi = 10.1016/0304-4017(79)90008-6 | title = The effects of bunamidine HCL on Hymenolepis diminuta in vitro | date = 1979 | vauthors = Chatfield RC, Yeary RA | journal = Veterinary Parasitology | volume = 5 | issue = 2–3 | pages = 177–193 }}</ref>


==References==
== References ==
{{reflist}}
{{reflist}}



Revision as of 19:07, 16 February 2024

Bunamidine
Identifiers
  • N,N-Dibutyl-4-hexoxynaphthalene-1-carboximidamide
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC25H38N2O
Molar mass382.592 g·mol−1
3D model (JSmol)
  • CCCCCCOC1=CC=C(C2=CC=CC=C21)C(=N)N(CCCC)CCCC
  • InChI=1S/C25H38N2O/c1-4-7-10-13-20-28-24-17-16-23(21-14-11-12-15-22(21)24)25(26)27(18-8-5-2)19-9-6-3/h11-12,14-17,26H,4-10,13,18-20H2,1-3H3
  • Key:FGGFIMIICGZCCJ-UHFFFAOYSA-N

Bunamidine is an anthelmintic drug used in veterinary medicine to treat infections by tapeworm parasites of the genus Taenia;[1] thus it is classified as a taeniacide.

It is also effective against Echinococcus granulosus (dog tapeworm)[2] and Hymenolepis diminuta (rat tapeworm).[3]

References

  1. ^ "Bunamidine". DrugBank.
  2. ^ Andersen FL, Loveless RM, Jensen LA (May 1975). "Efficacy of bunamidine hydrochloride against immature and mature stages of Echinococcus granulosus". American Journal of Veterinary Research. 36 (5): 673–675. PMID 1169897.
  3. ^ Chatfield RC, Yeary RA (1979). "The effects of bunamidine HCL on Hymenolepis diminuta in vitro". Veterinary Parasitology. 5 (2–3): 177–193. doi:10.1016/0304-4017(79)90008-6.