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The most well-known abortaficient drugs are [[RU 486]] ([[mifeprestone]]) and [[misoprostol]].
The most well-known abortaficient drugs are [[RU 486]] ([[mifeprestone]]) and [[misoprostol]].

Misoprostol is a prostaglandin E1 (PGE1) analogue used for the treatment and prevention of stomach ulcers. It is currently marketed by Pfizer under the trade name Cytotec.

More recently, misoprostol has been increasingly used for early termination of pregnancy (see abortion). It is used in conjunction with mifepristone (RU-486). After mifepristone is taken orally, misoprostol is taken 24-72 hours later causing the expulsion of the fetus and associated matter within four hours.

In countries where abortion is illegal, misoprostol is commonly being used to cause an abortion without medical supervision. This method is especially common in South American countries where misoprostol is avilable from pharmacies for other medical indications.

More common adverse effects of misopristol include nausea, vomiting, diarrhea, abdominal pain, chills, shivering and fever.
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Revision as of 16:30, 27 May 2005

An abortaficient is generally defined as a substance that causes premature expulsion of an embryo or fetus during pregnancy.

There exist pharmaceutical abortaficient drugs as well as herbs characterized as having abortaficient qualities. Abortaficients have the effect of causing premature uterine contractions that can end a pregnancy before the fetus has been carried to full term.

Abortaficient Drugs

The most well-known abortaficient drugs are RU 486 (mifeprestone) and misoprostol.

Misoprostol is a prostaglandin E1 (PGE1) analogue used for the treatment and prevention of stomach ulcers. It is currently marketed by Pfizer under the trade name Cytotec.

More recently, misoprostol has been increasingly used for early termination of pregnancy (see abortion). It is used in conjunction with mifepristone (RU-486). After mifepristone is taken orally, misoprostol is taken 24-72 hours later causing the expulsion of the fetus and associated matter within four hours.

In countries where abortion is illegal, misoprostol is commonly being used to cause an abortion without medical supervision. This method is especially common in South American countries where misoprostol is avilable from pharmacies for other medical indications.

More common adverse effects of misopristol include nausea, vomiting, diarrhea, abdominal pain, chills, shivering and fever.