Beta-phosphoglucomutase

In enzymology, a beta-phosphoglucomutase (EC 5.4.2.6) is an enzyme that catalyzes the chemical reaction

beta-D-glucose 1-phosphate $\rightleftharpoons$ beta-D-glucose 6-phosphate

Hence, this enzyme has one substrate, beta-D-glucose 1-phosphate, and one product, beta-D-glucose 6-phosphate.

This enzyme belongs to the family of isomerases, specifically the phosphotransferases (phosphomutases), which transfer phosphate groups within a molecule. The systematic name of this enzyme class is beta-D-glucose 1,6-phosphomutase. This enzyme participates in starch and sucrose metabolism.

Structural studies

As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 1LVH, 1O03, 1O08, 1Z4N, 1Z4O, and 1ZOL.

References

• Ben-Zvi R and Schramm M (1961). "A phosphoglucomutase specific for beta-glucose 1-phosphate". J. Biol. Chem. 236: 2186–2189.
• Boyer, P.D. (Ed.), The Enzymes, 3rd ed., vol. 6, 1972, p. 407-477.

External links

The CAS registry number for this enzyme class is Template:CAS registry.